• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제18권4호
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• pp.217-223
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• 2015

The obesity epidemic is a worldwide problem. Factors predisposing to obesity include genetics, race, socioeconomic conditions, birth by cesarean section, and perinatal antibiotic use. High protein (HP) content in infant formulas has been identified as a potential culprit predisposing to rapid weight gain in the first few months of life and leading to later obesity. In a large multicountry study the effects of lower protein (LP) formula (1.77 and 2.2 g protein/100 kcal, before and after the 5th month, respectively) were compared to those of higher protein (2.9 and 4.4 g protein/100 kcal, respectively). Results indicated that at 24 months, the weight-for-length z score of infants in the LP formula group was 0.20 (0.06, 0.34) lower than that of the HP group and was similar to that of the breastfed reference group. The authors concluded that a HP content of infant formula is associated with higher weight in the first 2 years of life but has no effect on length. LP intake in infancy might diminish the later risk of overweight and obesity. At 6 years of age HP children had a significantly higher body mass index (by 0.51; 95% confidence interval [CI], 0.13-0.90; p=0.009) and a 2.43 (95% CI, 1.12-5.27; p=0.024) fold greater risk of becoming obese than those who received the LP. In conclusion, several factors may influence development of metabolic syndrome and obesity. Breastfeeding should always be encouraged. An overall reduction of protein intake in formula non breastfed infants seems to be an additional way to prevent obesity.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2011년도 제40회 동계학술대회 초록집
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• pp.490-490
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• 2011

Graphene, hexagonal network of carbon atoms forming a one-atom thick planar sheet, has been emerged as a fascinating material for future nanoelectronics. Huge attention has been captured by its extraordinary electronic properties, such as bipolar conductance, half integer quantum Hall effect at room temperature, ballistic transport over ${\sim}0.4{\mu}m$ length and extremely high carrier mobility at room temperature. Several approaches have been developed to produce graphene, such as micromechanical cleavage of highly ordered pyrolytic graphite using adhesive tape, chemical reduction of exfoliated graphite oxide, epitaxial growth of graphene on SiC and single crystalline metal substrate, and chemical vapor deposition (CVD) synthesis. In particular, direct synthesis of graphene using metal catalytic substrate in CVD process provides a new way to large-scale production of graphene film for realization of graphene-based electronics. In this method, metal catalytic substrates including Ni and Cu have been used for CVD synthesis of graphene. There are two proposed mechanism of graphene synthesis: carbon diffusion and precipitation for graphene synthesized on Ni, and surface adsorption for graphene synthesized on Cu, namely, self-limiting growth mechanism, which can be divided by difference of carbon solubility of the metals. Here we present that large area, uniform, and layer controllable graphene synthesized on Cu catalytic substrate is achieved by acetylene-assisted CVD. The number of graphene layer can be simply controlled by adjusting acetylene injection time, verified by Raman spectroscopy. Structural features and full details of mechanism for the growth of layer controllable graphene on Cu were systematically explored by transmission electron microscopy, atomic force microscopy, and secondary ion mass spectroscopy.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2004년도 추계학술대회 논문집
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• pp.1131-1137
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• 2004

With the recent continuous expansion of subways, newly created subways tend to have lower locations and wider sections. Furthermore. since box structures and evacuating tunnels are classified into a category of mass-concrete. the thermal-stress, emitted from the inside. causes cracks to structures from the inception of constructing. In this paper, thermal-stress analysis and durability evaluation of box structure were carried out to investigate relationship between durability and parameter causing the heat of hydration. Through the examination, this paper tries to find out satisfactory solutions to regulated thermal crack and ensure the required duration period. The results of this paper showed that to control thermal crack and guarantee the required duration period it was more effective to use low-heat-portland cement and moderateheat-portland cement. As cement volume due to reduction of water-cement ratio increased, the possibility of thermal cracks occurrence increased but results of durability evaluation was different depending on evaluation method. The results showed that the appropriate water-cement ratio to control the heat of hydration and satisfy the required durability was $45\∼55\%$. And it was showed that during placement of concrete blocks ambient temperature affect the heat of hydration. thermal crack and long-term durability largely and when concrete was placed at low temperature to control thermal crack. it need to try to guarantee the required duration period. Henceforth, by studying not only internal and external conditions, such as the relative humidity and the unit weight. but also methods, to evaluate durability, in accordance with domestic situations, more reasonable design of durability should be achieved.

• 한국지하수토양환경학회지:지하수토양환경
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• 제29권1호
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• pp.18-27
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• 2024

In this study, the pump and fertilize (PAF) was applied to reduce nitrogen infiltration into groundwater at three corn cultivation sites over a three-year period, and its effectiveness was evaluated. PAF involves pumping nitrate-contaminated groundwater and using it for irrigation, thereby replacing the need for chemical fertilizers. This method not only substitutes chemical fertilization, but also reduces nitrogen infiltration into groundwater through root zone consumption. To confirm PAF's effectiveness, an equal amount of nitrogen was applied in each cultivation plot, either through chemical fertilizer or irrigation with nitrate-contaminated groundwater. Regular monitoring of infiltrating pore water and groundwater was conducted in each cultivation plot. The linear regression slope for nitrate concentration in the pore water after repeated application of PAF ranged from -3.527 to -8.3485 mg-N/L/yr, confirming that PAF can reduce nitrate concentration in the pore water. With an increasing proportion of PAF, the infiltrating nitrate mass in pore water was reduced by 42% compared to plots fertilized with chemical fertilizer. Additionally, the linear regression slope of nitrate concentration in groundwater was calculated as -2.2999 and -9.2456 mg-N/L/yr. Therefore, continuous application of PAF in rural areas is expected to significantly contribute to reducing nitrate concentration in groundwater.

• Journal of Microbiology and Biotechnology
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• 제33권12호
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• pp.1648-1656
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• 2023

We have previously observed that feeding with single-cell hemoprotein (heme-SCP) in dogs (1 g/day for 6 days) and broiler chickens (1 ppm for 32 days) increased the proportion of lactic acid bacteria in the gut while reducing their body weights by approximately 1~2%. To define the roles of heme-SCP in modulating body weight and gut microbiota, obese C57BL/6N mice were administered varied heme-SCP concentrations (0, 0.05, and 0.5% heme-SCP in high fat diet) for 28 days. The heme-SCP diet seemed to restrain weight gain till day 14, but the mice gained weight again later, showing no significant differences in weight. However, the heme-SCP-fed mice had stiffer and oilier bodies compared with those of the control mice, which had flabby bodies and dull coats. When mice were dissected at day 10, the obese mice fed with heme-SCP exhibited a reduction in subcutaneous fat with an increase in muscle mass. The effect of heme-SCP on the obesity-associated dyslipidemia tended to be corroborated by the blood parameters (triglyceride, total cholesterol, and C-reactive protein) at day 10, though the correlation was not clear at day 28. Notably, the heme-SCP diet altered gut microbiota, leading to the proliferation of known anti-obesity biomarkers such as Akkermansia, Alistipes, Oscillibacter, Ruminococcus, Roseburia, and Faecalibacterium. This study suggests the potential of heme-SCP as an anti-obesity supplement, which modulates serum biochemistry and gut microbiota in high-fat diet-induced obese mice.

• 콘크리트학회지
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• 제7권6호
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• pp.176-185
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• 1995

매스콘크리트 구조물에서 시멘트의 수화발열반응에 발생된 열은 약재령 콘크리트에서 내부온도의 증가와 체적변화를 일으키게 된다. 이와 같은 온도증가에 외부구속조건이 존재하게 되면, 구조물에는 인장응력이 발생하고 이는 구조물에 균열을 일으킬 수 있다. 따라서 매스콘크리트 구조물 건설시 수화열에 의한 온도증가를 제어하기 위해 다양한 시공기법을 이용하고 있으며, 이들 공법 중 하나가 관에 냉각수를 유입시켜 온도를 하강시키는 파이프쿨링 공법이다. 이 논문의 목적은 파이프쿨링을 실시할 때 수화열로 인한 온도이력을 모사할 수 있는 유한요소해석 프로그램을 개발하는 것이다. 이 연구에서 개발된 해석 프로그램의 결과와 실제 구조물의 기초부(11$\times$22cm)의 실측 결과가 잘 일치함을 보였다. 따라서 여기서 제시된 방법은 파이프쿨링으로 인한 콘크리트의 수화온도 예측에 유용하게 이용될 수 있을 것으로 판단된다.

• Journal of Microbiology and Biotechnology
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• 제28권9호
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• pp.1527-1535
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• 2018

Bacterial strain BAS23 was isolated from rice field soil and identified as Bacillus amyloliquefaciens. Based on dual culture method results, the bacterium BAS23 exhibited potent in vitro inhibitory activity on mycelial growth against a broad range of dirty panicle fungal pathogens of rice (Curvularia lunata, Fusarium semitectum and Helminthosporium oryzae). Cell-free culture of BAS23 displayed a significant effect on germ tube elongation and mycelial growth. The highest dry weight reduction (%) values of C. lunata, H. oryzae and F. semitectum were 92.7%, 75.7%, and 68.9%, respectively. Analysis of electrospray ionization-mass spectrometry (ESI-MS) and $^1H$ nuclear magnetic resonance (NMR) spectroscopy revealed that the lipopeptides were iturin A with a C14 side chain (C14 iturinic acid), and a C15 side chain (C15 iturinic acid), which were produced by BAS23 when it was cultured in nutrient broth (NB) for 72 h at $30^{\circ}C$. BAS23, the efficient antagonistic bacterium, also possessed in vitro multiple traits for plant growth promotion and improved rice seedling growth. The results indicated that BAS23 represents a useful option either for biocontrol or as a plant growth-promoting agent.

• 한국식품과학회지
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• 제29권6호
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• pp.1202-1207
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• 1997

가열 살균을 대체하여 식품의 신선도를 유지하면서 효과적으로 미생물을 사멸시킬 수 있는 새로운 비가열 살균기술로서 고압 $CO_2$, 처리를 고찰하고자 하였다. 이를 위해 김치에서 분리한 Leuconostoc sp.를 대상 미생물로 가압 조절인자를 달리하여 이 균주에 미치는 고압 $CO_2$의 살균 효과를 검토하였다. 사용 압력과 온도, 처리시간이 증가할수록, 이에 반해 작업용량은 감소할수록 균체의 사멸율이 증가하였으며, $30^{\circ}C$, $60\;kg/cm^2$의 $CO_2$가압 조건에서 젖산균 배양액을 $10^{-3}$만큼 감균하는데 약 150분이 소요되었다. 실험 결과로부터 고압 $CO_2$에 의한 미생물 살균은 기본적으로 $CO_2$의 세포내 침투에 의해 좌우되며, 따라서 세포 내부로의 $CO_2$ 전달 과정이 전체적인 살균 효율을 결정짓는 가장 중요한 단계임을 확인할 수 있었다.

• 대한화장품학회지
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• 제48권1호
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• pp.25-32
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• 2022

본 연구에서는 20 대 ~ 40 대 한국 여성을 대상으로 피부 수분량, 피부 멜라닌, 피부 붉은기, 피부 비틀림 탄력을 측정하여 기초 피부 특성 데이터를 수집하고, 이를 나이와 상관성 분석을 진행하여 피부 지수를 만들고 이에 기반 하여 4 개의 군집으로 분류하여 그 특성을 확인하였다. 그 후 시제품 2 종을 2 주간 사용하여 피부 수분량, 피부 붉은기, 피부 각질량 감소에 대한 개선 효과를 확인한 후, 해당 시험자 중 피부 특성시험에 참여했던 피험자들을 대상으로 어느 군집에서 어떤 제품이 더 효과적이었는지 분석하였다. 이를 통해 피부 지수와 군집분석결과를 제품 효능평가에 반영하여 맞춤형 화장품 시장에 대비할 수 있는 가능성을 확인하였다.

• 한국구조물진단유지관리공학회 논문집
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• 제13권1호통권53호
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• pp.97-105
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• 2009

건설산업에서 혼합콘크리트의 개발 및 사용은 내구성 측면에서의 공극구조개선 및 투수성 감소등의 확장 연구를 통해 나날이 증가하고 있는 실정이다. 한편, 콘크리트내의 균열은 투수성, 염해 침투속도 및 압축강도등을 결정하는 중요한 인자이며, 이는 철근의 부식과도 밀접한 관련을 가지는 것으로 알려져 있다. 더욱이 콘크리트 구조물의 피복두께에 균열이 발생한 경우, 이를 통해 철근 부식이 가속화됨은 주지의 사실이다. 최근에 콘크리트내의 침투를 고려한 균열효과와 관련하여 다수의 연구가 수행되어져 온 것이 사실이며, 그에 따라 내구성을 고려한 균열 혼합콘크리트의 사용수명 평가에 관한 연구도 필요한 것이 사실이다. 본 연구에서는 0.3mm의 균열을 변수로 두고, OPC, 30% PFA, 60% GGBS 및 10% SF의 결합재를 혼입하여 사용한 혼합콘크리트보의 부식평가를 자연 및 인공 환경조건에 맞추어 반전지전위측정시험, 갈바닉전류측정시험, 무게감량법등으로 측정 및 비교분석하였다.