• Title/Summary/Keyword: Effect of Regulation

Search Result 3,136, Processing Time 0.041 seconds

Regulation of $\beta$-Galactosidase Biosynthesis in Alkalophilic, Thermophilic Bacillus sp. TA-11 (호알칼리성, 고온성 Bacillus sp. TA-11의 $\beta$-galactosidase의 생합성 조절)

  • Lee, Jong-Su;Lee, Hyang-Sook
    • The Journal of Natural Sciences
    • /
    • v.5 no.2
    • /
    • pp.13-17
    • /
    • 1992
  • Regulation of $\beta$-galactosidase biosynthesis was studied with alkalophilic, thermophilic Bacillus sp. TA-11. Biosynthesis of the enzyme was effectively induced by lactose and some low level by isoprophyl-$\beta$-D-thiogalactopyranoside(IPTG). When 30mM glucose was added at the different intervals to the culture that had been in contact with lactose, the different levels of the enzyme synthesis were observed. So, this suggests that glucose interfered with the entry of the lactose into the cells.The glucose inhibitory effect was not relieved by adding cAMP to the culture.

  • PDF

A Comparative Analysis of the Functional Values for Wastewater Treatment and Atmospheric Regulation in Coastal Wetland and Rice Paddy Ecosystems (갯벌과 간척농지의 수질 및 대기조절가치의 비교분석)

  • Pyo, Hee-Dong
    • Environmental and Resource Economics Review
    • /
    • v.10 no.1
    • /
    • pp.95-126
    • /
    • 2001
  • Functional values for wastewater treatment and atmospheric regulation in coastal wetland and rice paddy ecosystems are quantified, and an illustration is given on how to integrate biophysical parameters into a valuation framework. This is one of most controversial issues in economic analysis for wetland preservation versus wetland conversion to agricultural use. This paper includes theoretical considerations for estimating functional values of environmental ecosystems, and the integration of biophysical data and replacement cost method employed. Specific physical and geographical characteristics and data on ecosystem functions and services in coastal wetlands and rice paddies are addressed for evaluating their values in economic terms. In particular this paper indicates double counting problems and overestimation in the previous studies, and demonstrates how to avoid them and to maintain the consistency of valuation process involving a least-cost method, thus enables an accurate integration of the coastal wetland ecology and wetland economics. As a result which is far away from the previous studies, the total economic present value of wastewater assimilation by coastal wetland is estimated at 7,484,640 won/ha, and the net present value of positive effect for atmospheric regulation, negative effects for air pollution and water pollution by rice paddy is estimated at -37,934 won/ha, assuming that resources are infinitely long-lived and the annual value and the rate of discount (10%) is constant every year. In conclusion, for further reliability and validity of functional values for natural resources it is very noteworthy that a general equilibrium framework that could directly incorporate the interdependence between ecosystem functions and services would be preferred to the partial equilibrium framework.

  • PDF

Effect Factors of Adolescences' Suicide risk (청소년 자살위험성에 영향을 미치는 요인)

  • Kim, Hyun-Ju
    • Journal of the Korean Society of Child Welfare
    • /
    • no.27
    • /
    • pp.69-93
    • /
    • 2008
  • The study tried to identify suicidal factors of adolescences by analyzing effect factors of adolescences' suicide. Demographic factor, Self-respect, depression, suicidal ideation, and school adjustment scale, Social support, self-regulation, and problem solving scale were analyzed as effect factors. 307 junior high and high school students in Pusan city were surveyed by community education experts for this research. As a result, there are significant differences between high suicidal risk group and low suicidal group in all subcategories including economic status. As for the correlation analysis between risk factors and preventive factors, variables, it was analyzed that each variable was correlated to other variables. In addition, multiple regression analysis was conducted to find out affecting factors of adolescence suicide categorized into demographic factor, personal factor, school factor, and social factor. As a result, it was founded that the affecting factors of adolescence suicide were school adjustment, problem solving ability, suicidal ideation, depression and neighborsupport, and self-regulation. That is, to prevent adolescence suicide, the adolescence who are exposed to suicidal risk should be identified by measuring the degree of suicidal ideation, strengthened their school adjustment, and then conducted group therapy to strengthen their problem solving ability and self-regulation. In addition, adolescence suicide can be prevented by strengtheningsocial support for adolescences.

The Dual Mediating Effect of Fear of Compassion and the Difficulties of Emotional Regulation on the Relationship between Attachment Trauma and Interpersonal Problems (애착외상과 대인관계문제의 관계에서 자비두려움과 정서조절곤란의 이중매개효과)

  • Kang, Minjeong;Cho, Hyunju
    • Korean Journal of School Psychology
    • /
    • v.18 no.1
    • /
    • pp.71-97
    • /
    • 2021
  • The purpose of this study was to examine the mediating effects of the fear of compassion and the difficulties of emotional regulation on the relationship between attachment trauma and interpersonal problems. The participants in this study were 296 Korean university students. The participants completed self-report questionnaires that assessed their attachment trauma, fear of compassion, emotional regulation difficulties, and interpersonal problems. Those with high attachment trauma had significantly more interpersonal problems, fear of compassion from others, fear of self-compassion, and emotional regulation difficulties than those with low attachment trauma. Further, fear of compassion and difficulties in emotional regulation were shown to fully mediate and fully dual-mediate the relationship between attachment trauma and interpersonal problems. These findings suggest that attachment trauma affects the degree to which university students experience interpersonal problems and that fear of compassion and emotional regulation difficulties may be the mechanism underlying that relationship. This paper discusses several limitations of this study and areas for future research.

Immunocytochemical Localization of c-raf Protein Kinase in EC-4 Cell (EC-4 세포에 있어서 c-raf Protein Kinase의 면역세포화학적 위치)

  • 최원철
    • The Korean Journal of Zoology
    • /
    • v.33 no.3
    • /
    • pp.266-275
    • /
    • 1990
  • c-raf protein kinase, a kind of oncogene, is a cytopiasmic serine / threonine-specific protein and is activated by mitogenic or oncogenic signals. The strncture and functions of c-raf protein kinase are considered very similar to those of protein kinase C. Using immunocytochemical approach, the time course of singal transduction of c-raf protein kinase in EC-4 cell was examined with 12-0-tetradecanoylphorbol-13-acetate (TPA) as tumor promotor and plateletderived growth factor (PDGF) as mitogenic factor. Immunoreactive c-raf was initially bound to the perinuclear membrane and then moved into the nucleus. The effect of the long-term treatment with TPA or PDGF was taken place down regulation at different time point. These results indicate that TPA and PDGF give rise to the translocation of c-raf protein kinase through the two different pathways.

  • PDF

Effect of Horticultural Therapy on Anger Control of the Primary Caregivers for Dementia Patients (원예치료가 치매 환자 주 부양자의 분노조절에 미치는 영향)

  • Kyung-Nam Park;Gye-yeong Heo
    • Journal of Environmental Science International
    • /
    • v.32 no.1
    • /
    • pp.1-9
    • /
    • 2023
  • In this study, a horticultural therapy program was performed by employing the anger experienced by people during daily life activities in the emotion regulation strategy-based program to identify the influence of the horticultural program on anger control in the caregivers for patients with dementia. To measure this influence, two tools were used: a self-administered questionnaire survey, which is a subjective test, and an instrumental test, which can measure the physical index that detects the physical changes through anger. For the preliminary test, depression, stress, self-esteem, anxiety, and anger state-characteristic were tested using the self-administered questionnaire. For the follow-up test, the self-administered survey and the test using the physical index were performed in a manner similar to that of the preliminary test. The self-administered questionnaire comprised questions suitable to this study and considered the age, education level, and economic aspect of the subjects. The test results indicated that the experimental group subjected to the emotion regulation strategy-based horticultural therapy showed very significant reduction in depression and anger and significant reduction in stress, self-esteem, and anxiety. In the physical index test, the systolic and diastolic blood pressures were reduced, and the pulse rate and respiration rate reduced before and after the therapy, thus, proving the effectiveness of the therapy in anger control.

Systematic Review of the Effects of Blood Flow Exercise for Health-care Promotion: A Focus on Korean Domestic Research (헬스케어 증진을 위한 혈류조절 가압 운동의 효과에 대한 체계적 문헌고찰 ; 국내 연구 중심으로)

  • Seo, Tae-Hwa;Kim, Dong-Won
    • Journal of Korea Entertainment Industry Association
    • /
    • v.14 no.8
    • /
    • pp.447-454
    • /
    • 2020
  • The purpose of this study was to determine the clinical effects of blood flow regulation exercise for improving patients' health care and its usefulness as a rehabilitation model for various diseases by analyzing and examining the existing literature. A literature review of Korean academic journals published over a 10-year period, from 2010 to 2019, was conducted using words such as "blood flow regulation," "blood flow restriction," "low-intensity exercise," and "Kaatsu." Kaatsu is a blood flow regulation exercise developed in 1966 by Dr. Yoshiaki Sato of Japan. It is an efficient and effective exercise method that uses blood flow regulation bands that increase the secretion of growth hormones to develop muscles within a short time, improves blood circulation and metabolism to prevent and improve adult diseases, shortens the rehabilitation period, and improves cardiovascular function. The study participants consisted of 10 patients, of whom four were elderly, four had obesity, one was a stroke patient, and one was a trauma patient. The results of this study show that the blood flow regulation exercise, which is a low-intensity exercise, has the same effect as high-intensity exercise, which supports the evidence that it is a highly efficient exercise method for muscle development and rehabilitation of the elderly, adolescents, and patients with injuries who have difficulty in general exercising. For future studies, further reviews are necessary to verify the effectiveness of the exercise method according to blood flow regulation site and type of disease.

Line Voltage Regulation of Urban Transit Systems Using Supercapacitors (슈퍼커패시터를 이용한 도시형 철도의 가선전압 안정화)

  • Son, Kyoung-Min;Choi, Jae-Ho;Kim, Hyung-Chul
    • The Transactions of the Korean Institute of Power Electronics
    • /
    • v.14 no.6
    • /
    • pp.481-487
    • /
    • 2009
  • This paper proposes a regulation method of DC line voltage for urban transit system fluctuated during the acceleration or deceleration by using supercapacitor. Supercapacitor is modelled electrically under the assumption of three different time constants of RC circuits with variable capacitances depending on the voltage. And its parameters are determined by the experimental measurements. The energy storage system using supercapacitors is installed based on this model, and the proposed model is tested through the simulations and experiments, and the controller for charging and discharging is designed. Finally, it is tested at Kyoungsan test site for the urban light rail road system and the energy saving effect is evaluated economically.

Convergence study of the factors affecting positive psychology capital among nursing students (간호대학생의 긍정심리자본에 대한 융합적 영향요인)

  • Lee, So-Young;Lee, Kyung-hee
    • Journal of the Korea Convergence Society
    • /
    • v.9 no.5
    • /
    • pp.269-279
    • /
    • 2018
  • This study aimed to investigate the relationship among positive psychology capital, social support and emotion regulation ability of nursing college students and to examine the effect of social support and emotion regulation ability on positive psychology capital. 157 nursing college students were participated in the study. Data were collected by structured questionnaire and analyzed by SPSS / Win 21.0 program. The results showed that the level of positive psychology capital among nursing college students was above middle level(3.68/5), and there was a significant positive correlation among positive psychology capital and social support and emotional regulation ability. The results showed that factors affecting positive psychological capital were gender (${\beta}=-.11$), teaching relationship (${\beta}=.16$), evaluation support (${\beta}=.40$) and self emotion regulation (${\beta}=.39$). The overall explanatory power of the model was 68%, and by emotional self control of the emotion regulation ability explanatory power of the positive psychological capital was 9%. In order to enhance positive psychology capital of nursing college students, it is an effective strategy to develop and provide an emotional regulation program.

Antiproliferative Effect and Apoptotic Mechanism of Extract of Corydalis Yanhusuo on Human Hepatocarcinoma Cells (현호색(玄胡索)이 인체간암세포 증식억제 및 apoptosis 유발에 미치는 영향)

  • Oh, Myun- Taek;Eom, Hyun-Sup;Chi, Gyoo-Yong
    • Journal of Physiology & Pathology in Korean Medicine
    • /
    • v.21 no.6
    • /
    • pp.1437-1449
    • /
    • 2007
  • In this study, the effect of extract of Corydalis yanhusuo (ECT) used in Oriental medicine therapy was investigated on the cell growth and apoptosis of HepG2 human hepatoma cells. It was found that ECT could inhibit the cell growth effectively in a dose-dependent manner, which was associated with morphological change and apoptotic cell death such as formation of apoptotic bodies, DNA fragmentation and increased populations of apoptotic-sub G1 phase. And we observed the effects of ECT on loss of mitochondrial membrane potential (MMP), using the JC-1 probe by DNA flow cytometric analysis. Apoptosis of HepG2 cells by ECT was associated with a down-regulation of anti apoptotic Bcl-2 expression, inhibitor of apoptosis proteins (IAPs) expression and proteolytic activation of caspase-3 and caspase-9. However, ECT did not affect the pro-apoptotic Bax expression and activity of caspase-8. ECT treatment also concomitant degradation and /or inhibition of poly (ADP-ribose) polymerase (PARP), phospholipase C-1 ($PLC{\gamma}1$). Furthermore, ECT treatment caused a dose-dependent inhibition of iNOS and cyclooxygenase-2 (Cox-2). Additionally ECT have been implicated in the regulation of telomerase expression. ECT treatment induced the down-regulation of telomerase reverse transcriptase mRNA (hTERT) expression of HepG2 cells. Taken together, these findings suggest that ECT may be a potential chemotherapeutic agent for the control of HepG2 human hepatoma cells.