• Korean Journal of Child Studies
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• v.29 no.5
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• pp.285-299
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• 2008

This study examined the moderating role of self-control and emotion regulation in the relationship between academic stress and mental health among Korean adolescents. The Korean Youth Panel Study (KYPS) was used as sample data with a total of 3121 $11^{th}$ grade students involved in this study. Hierarchical multiple regression was applied to test the moderation model following Baron & Kenny's (1986) model. Results revealed that self-control (for male adolescents) and emotion regulation (for female adolescents) played the role of moderators in the relationship between academic stress and mental health problems. Academic stress proved to have a negative effect on mental health of adolescents.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.05b
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• pp.651-656
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• 1997

Efforts are made to examine the role nuclear energy under the international carbon emissions regulation. To do so, an econometric model for energy demand and supply is developed. Here, several scenarios on the regulation are assumed and then each scenario is analyzed by using this model. This model also makes it Possible to analyze the effect of carbon tax. The results show that share nuclear increases up to 60% in 2020 Instead 45% makes GDP rise by 1.9% while the electricity price lower by 46% in carbon emission regulation.

• BMB Reports
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• v.57 no.3
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• pp.149-154
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• 2024

The stomach has emerged as a crucial endocrine organ in the regulation of feeding since the discovery of ghrelin. Gut-derived hormones, such as ghrelin and cholecystokinin, can act through the vagus nerve. We previously reported the satiety effect of hypothalamic clusterin, but the impact of peripheral clusterin remains unknown. In this study, we administered clusterin intraperitoneally to mice and observed its ability to suppress fasting-driven food intake. Interestingly, we found its synergism with cholecystokinin and antagonism with ghrelin. These effects were accompanied by increased c-fos immunoreactivity in nucleus tractus solitarius, area postrema, and hypothalamic paraventricular nucleus. Notably, truncal vagotomy abolished this response. The stomach expressed clusterin at high levels among the organs, and gastric clusterin was detected in specific enteroendocrine cells and the submucosal plexus. Gastric clusterin expression decreased after fasting but recovered after 2 hours of refeeding. Furthermore, we confirmed that stomachspecific overexpression of clusterin reduced food intake after overnight fasting. These results suggest that gastric clusterin may function as a gut-derived peptide involved in the regulation of feeding through the gut-brain axis.

• BMB Reports
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• v.54 no.2
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• pp.124-129
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• 2021

In current times, obesity is a major health problem closely associated with metabolic disease such as diabetes, dyslipidemia, and cardiovascular disease. The direct cause of obesity is known as an abnormal increase in fat cell size and the adipocyte pool. Hyperplasia, the increase in number of adipocytes, results from adipogenesis in which preadipocytes differentiate into mature adipocytes. Adipogenesis is regulated by local and systemic cues that alter transduction pathways and subsequent control of adipogenic transcription factors. Therefore, the regulation of adipogenesis is an important target for preventing obesity. Myonectin, a member of the CTRP family, is a type of myokine released by skeletal muscle cells. Although several studies have shown that myonectin is associated with lipid metabolism, the role of myonectin during adipogenesis is not known. Here, we demonstrate the role of myonectin during adipocyte differentiation of 3T3-L1 cells. We found that myonectin inhibits the adipogenesis of 3T3-L1 preadipocytes with a reduction in the expression of adipogenic transcription factors such as C/EBPα, β and PPARγ. Furthermore, we show that myonectin has an inhibitory effect on adipogenesis through the regulation of the p38 MAPK pathway and CHOP. These findings suggest that myonectin may be a novel therapeutic target for the prevention of obesity.

• Molecules and Cells
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• v.38 no.1
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• pp.75-80
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• 2015

Osteoclasts are unique cells responsible for the resorption of bone matrix. MicroRNAs (miRNAs) are involved in the regulation of a wide range of physiological processes. Here, we examined the role of miR-26a in RANKL-induced osteoclastogenesis. The expression of miR-26a was upregulated by RANKL at the late stage of osteoclastogenesis. Ectopic expression of an miR-26a mimic in osteoclast precursor cells attenuated osteoclast formation, actin-ring formation, and bone resorption by suppressing the expression of connective tissue growth factor/CCN family 2 (CTGF/CCN2), which can promote osteoclast formation via upregulation of dendritic cell-specific transmembrane protein (DC-STAMP). On the other hand, overexpression of miR-26a inhibitor enhanced RANKL-induced osteoclast formation and function as well as CTGF expression. In addition, the inhibitory effect of miR-26a on osteoclast formation and function was prevented by treatment with recombinant CTGF. Collectively, our results suggest that miR-26a modulates osteoclast formation and function through the regulation of CTGF.

• Journal of Industrial Convergence
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• v.20 no.3
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• pp.1-10
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• 2022

The results(Boje et al. 2004) suggest that corporate image is severely damaged due to arrogance and a sense of power among some of the executives. With the advent of the MZ generation, the humility of leaders who lead the organization becomes more and more important(Morris et al. 2005; Vera, Rodriguez-Lopez, 2004; Owens et al. 2013). This paper tried to empirically analyze the mediating effect of emotional regulation in the relationship between humble leadership, voice behavior, and innovative behavior. To this end, a survey was conducted from November to December 2021 for corporate employees in Busan, Gyeongnam, and Gyeongbuk, and was empirically analyzed through the results of a total of 145 surveys. As a result, it was verified that humble leadership had a positive(+) effect on voice behavior and innovative behavior, and the mediating effect of emotional regulation in the relationship between humble leadership and voice behavior and innovative behavior was also verified. Through this, this study expanded the scope of research by newly illuminating the relationship between humble leadership and emotional regulation, which are the core competencies of leaders, and revealing the causal relationship. In future research, we intend to explore the relationship between humble leadership and various variables and to investigate the relationship through various research methods.

• Korean Journal of Family Social Work
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• no.56
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• pp.105-133
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• 2017

The purpose of this study was to examine the relationship between family strength and career decision-making difficulties and the mediating effect or career self-regulation. The results of the present study suggested the significance of family strength and career self-regulation in understanding career decision-making difficulties. With 172 Korean college students, there were both significant direct and indirect effects from family strength to career decision-making difficulties. Specifically, the mediation roles of career self-regulation was confirmed. Comparing the partial mediation model with full mediation model, the partial mediation model fits better with the data. These results have significant clinical implication that counseling practitioners need to address the possible influence of family strength on college student's perceived difficulties in career decision-making process and to assist students develop appropriate level of competencies of regulating one's emotion, thoughts, and behavior related to career problems.

• Microbiology and Biotechnology Letters
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• v.34 no.1
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• pp.35-39
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• 2006

One of the fermentative metabolism of enteric Escherichia coli was imitated after rumen bacteria, which have high C4 metabolism. E. coli expresses phosphenolpyruvate carboxylase (PPC) for the pathway between phosphoenolpyruvate (PEP) and oxaloacetate (OAA) during glycolytic condition while expresses phosphoenolpyruvate carboxykinase (PCK) during gluconeogenic condition. In contrast to enteric E. coli, rumen bacteria express the PEP-OAA pathway only by PCK. To verify the effect of the regulation imitation on the C4 metabolism of E. coli, PPC-deficient E. coli strain with PCK expression in glycolytic condition was constructed. The PEP-OAA regulation modified E. coli strain increased 2.5-folds higher C4 metabolite than the wild type strain. The potential use of C4 metabolism by regulation control is discussed.

• Korea Journal of Hospital Management
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• v.22 no.4
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• pp.102-112
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• 2017

[purpose] This study was conducted to identify how a hospital's outsourcing workers' QWL influences Turnover Intention and to determine Dual Commitment cause any discrepancies in regards to the link between QWL and Turnover Intention. [Methodology/Approach] The study is based on 254 survey sheets answered by outsourcing employees working at general hospitals with more than 300 beds in Seoul and the methods of analysis used are as follows: reliability analysis, correlation analysis, multiple regression analysis, and hierarchical regressions analysis. [Findings] The study results First, analyzing how different types of QWL (individual, organizational, managemental) influence Turnover Intention, R2 turned out to be 30.7% and organizational factors and managemental factors show a statistically significant difference. In addition, organizational and managemental factors have negative effects on Turnover Intention while that of organization factors has a bigger influence. Second, verifying regulation effects of Dual Commitment in regards to the link between QWL and Turnover Intention, it is learned that Dual Commitment (hiring firm) has no regulation effects on the link. However, it does have a regulation effect on the link between QWL (managemental) and Turnover Intention. Moreover, after verifying regulation effects of Dual Commitment (client's firm), it is learned that it has regulation effect on the link between QWL (organizational and managemental) and Trunover Intention. [Practical Implications] In conclusion, lower Turnover Intention, it is necessary to impose tasks that suit the employees' competence and to encourage efficiency throughout clear communications and accurate directions.

• Journal of Digital Convergence
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• v.19 no.1
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• pp.295-305
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• 2021

This study identifies the relationship between the anger expression and interpersonal problems of college students, and then confirms the influence on emotion regulation difficulties as a mediating effect. And, it was conducted to understand college students who complain of interpersonal problems and to provide basic data for developing programs that can solve their problems. As a result of the study, anger expression showed a positive correlation in interpersonal relations problem and emotion regulation difficulty, and interpersonal relations problem showed somewhat high positive correlation with emotion regulation difficulty. In addition, it was found that emotion control difficulties were partially mediated in the anger expression among college students and interpersonal relationships. In conclusion, we could see the need for future research to develop educational programs that reduce the difficulty of emotion control and lead to positive anger expression among college students, and intervention programs that can improve interpersonal relationships.