• 한국식품과학회지
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• 제9권3호
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• pp.194-198
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• 1977

제주산(濟州産) 감태(甘苔)에 $0.1{\sim}6\;Mrad$의 감마선을 조사(照射)후 알진산(酸)의 추출수율(收率)과 점도(粘度)특성을 알아본 결과는 다음과 같다. 1 Mrad 이하의 감마선 조사는 대조구보다 70% 이상의 수율증가를 가져왔으며 그 이상의 감마선 조사는 오히려 수율이 약간 떨어졌다. 알진산(酸)의 점도(粘度)특성은 0.5 Mrad 조사구까지 대조구와 큰차이가 없었으나 1 Mrad 이상의 조사는 중합도(重合度)의 저하(低下)에 따른 점도(粘度)의 감소를 초래하였다.

• 한국수산과학회지
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• 제17권5호
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• pp.391-397
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• 1984

The seasonal and portional variation in the composition of uronic acid of alginic acid from Eckionia cava was investigated. The sample was collected from the coast of Ieechun Illkwangmyun, Yangsangun, Kyungnam, Korea, in the period of January to December in 1982. In seasonal variation of the content of alginic acid, the range of variation was larger in the frond than in the stipe, It was the highest content in between February to April, and the lowest in between August to October, and the content was more in the stipe than in the frond. The uronic acid ratio(M/G ratio) was varied seasonaly in a relationship with the variation of the alginic acid content. The maximum M/G ratio appeared in the period of December to March and minimum May to August, and the average values of the M/G ratios in the periods were 3.08, 2.64 in the frond and 2.91, 1.39 in the stipe, respectively. Additively a year mean values were 3.22 in the frond and 2.18 in the stipe.

• 한국식품영양과학회지
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• 제34권8호
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• pp.1293-1296
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• 2005

일상 식생활에서 널리 섭취하고 있는 식용 및 미식용인 16종의 해조류를 사용하여 니트로사민의 직접적인 생성인자인 아질산염 소거작용에 관하여 검토하였다. 그 결과, 갈조류의 경우가 녹조류 및 홍조류에 비해 우수한 분해효과를 나타내었으며 갈조류 중에서도 다시마과의 감태, 곰피, 구멍쇠 미역이 뛰어난 아질산염 분해효과를 나타내었다. 또한 각 시료 모두 pH의존성이 크게 나타나 pH 4.2 및 6.0에서 보다 pH 1.2에서 아질산염 분해효과가 뛰어났으며 아질산염 분해효과가 우수할수록 환원력이 높아 아질산염 분해능과 환원력은 밀접한 관련성을 나타내었다.

• 약학회지
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• 제40권5호
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• pp.574-581
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• 1996

The study was initiated to elucidate the protective mechanism by examining in vivo effect of some marine natural products, Styela plicata, Ecklonia stolonifera and Pachymeniopsis elliptica on acetaminophen-induced lipid peroxidation. The methanol extract of S. plicata prevented acetaminophen (800mg/kg, i.p.)-induced hepatotoxicity in rats as evidenced by the decreased formation of lipid peroxide. But the methanol extracts of E. stolonifera and P. elliptica were not affected on the formation of lipid peroxidation. The activities of cytochrome P-450, animopyrine N-demethylase and aniline hydroxylase were not changed by the treatment with S. plicata in comparison with acetaminophen-teated group. In acetaminophen-treated control rats, the glutathione S-transferase activity was decreased markably. However. in S. plicata pretreated group, the effect caused by acetaminophen was markably reduced. A-cetaminophen decreased the level of hepatic, glutathione, which was restored to same degree by S. plicata pretreatment. And activity of ${\gamma}$-glutamylcystein synthetase was not changed by S. plicata pretreatment, but the activity of glutathione reductase was increased significantly.

• 한국환경성돌연변이발암원학회지
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• 제25권4호
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• pp.129-133
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• 2005

We investigated the cytoprotective effect of phloroglucinol, which was isolated from Ecklonia cava (brown seaweed), against oxidative stress induced cell damage in Chinese hamster lung fibroblast(V79-4) cells. Phloroglucinol was found to scavenge intracellular reactive oxygen species (ROS) generated by $\gamma-ray$ radiation. In addition, Phloroglucinol inhibited cell damage induced by radiation through scavenging ROS. Phloroglucinol increased the superoxide dismutase and glutathione peroxidase activity, Taken together, the results suggest that phloroglucinol protectes V79-4 cells against oxidative damage by enhancing the cellular antioxidant enzymes activity.

• 생약학회지
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• 제24권4호
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• pp.299-303
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• 1993

The antioxidant activity of methanol extracts of plants and marine algae was tested by using 1,1-diphenyl-2-picrylhydrazyl(DPPH). Five plant extracts(Prunus davidiana, Eriobotrya japonica, Artemisia iwayomogi, Stirodella tolyrrhiza and Ulmus davidiana) and two algae (Ecklonia stolonifera and Symphycoladia latiuscula) were found to be the most effective in DPPH radical scavenging activity. The methanol extract obtained from the stems of Prunus davidiana was fractionated with several solvents. The ethylacetate soluble fraction exhibiting the strongest antioxidant activity was further purified by repeated silica gel and Sephadex LH-20 column chromatography. Antioxidant flavonoids and flavonoid glycosides were isolated and the most active ones was identified as (+)-catechin by MS, $^1H-NMR$ and $^{13}C-NMR$. Its antioxidant activity was higher than that oil vitamin C.

• 한국패류학회지
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• 제25권3호
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• pp.231-236
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• 2009

This study describes biological environmental characteristics in natural habitats of Haliotis diversicolor in the coastal area of Sungsanpo located in the eastern coast of Jeju-do, Korea. The field survey was monthly conducted from May 2006 to February 2007. H. diversicolor, sea urchin, turban shell and marine algae were collected by two divers using SCUBA. The species composition of demersal fishes were seasonally investigated by fish traps in 2007. During the study period, more than 67% of H. diversicolor and sea urchin were found in the depth shallower than 5 m, and more than 64% of turban shell were found in the depth deeper than 3 m. The dominant algal species in May were generally Undaria pinnatifida, Ecklonia cava, Sargassum. spp. and coralline algae. Most of demersal fishes collected by the fish traps were wrasses which have been reported as a major predator of young abalone.

• Fisheries and Aquatic Sciences
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• 제26권3호
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• pp.181-187
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• 2023

The control of intestinal α-amylase and α-glucosidase is an effective therapeutic strategy for prevention of post-prandial hyperglycemia associated with diabetes mellitus. The objective of this study was to evaluate the anti-diabetes activities of Korean edible seaweed against α-amylase and α-glucosidase, two carbolytic enzymes involved in serum glucose regulation. Of the 41 species initially screened, Cladophora wrightiana var. minor, Eisenia bicyclis, Ecklonia cava, Ishige foliacea, and Ishige okamurae exhibited the strongest inhibitory activities from brown seaweeds. Asparagopsis taxiformis showed the strongest inhibitory effects from red seaweeds. The results of this study suggest that the crude brown seaweed extracts (C. wrightiana var. minor, E. bicyclis, E. cava, I. foliacea, and I. okamurae) and crude red seaweed extracts (A. taxiformis) may have beneficial effects suppressing the rise in postprandial hyperglycemia through the inhibition of α-amylase and α-glucosidase.

• Biomolecules & Therapeutics
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• 제23권3호
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• pp.238-244
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• 2015

Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22 levels are elevated in atopic dermatitis, which suggests that the chemokines produced from keratinocytes are responsible for attracting inflammatory lymphocytes to the skin. A major signaling pathway in the interferon-${\gamma}$ (IFN-${\gamma}$)-stimulated inflammation response involves the signal transducers and activators of transcription 1 (STAT1). In the present study, we investigated the anti-inflammatory effect of dieckol and its possible action mechanisms in the category of skin inflammation including atopic dermatitis. Dieckol inhibited MDC/CCL22 production induced by IFN-${\gamma}$ (10 ng/mL) in a dose dependent manner. Dieckol (5 and $10{\mu}M$) suppressed the phosphorylation and the nuclear translocation of STAT1. These results suggest that dieckol exhibits anti-inflammatory effect via the down-regulation of STAT1 activation.

• Environmental Analysis Health and Toxicology
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• 제17권4호
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• pp.341-346
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• 2002

제주도 연안의 수산물 생산력 향상을 위해서는 연안 해양환경 보전이 무엇보다 중요하다. 특히 골프장의 농약 오염원이 연안환경과 수산생물에 미치는 영향을 규명할 필요가 있다. 따라서 제주도의 농업 오염물질 중 유기인계 농약에 의한 연안해역의 오염을 규명하고자, 1997년 7월과 8월에 남제주도에 위치한 중문골프장에 인접한 색달동과 대포동 근해 해양환경시료에서 monocrotophos와 EPN 유기 인계 농약 잔류를 조사하였다. GC-FPD에 의한 monocrotophos와 EPN의 시료중 최소 검출농도는 동·식물의 고체시료에서는 0.024 ng/g, 0.020 ng/g이었다. 또한 해수에서는 각각 0.012 ng/mL, 0.010 ng/mL이었다. 식물시료인 우뭇가사리와 미역, 동물시료인 소라와 성게에 대한 유기인계 농약의 잔류량 조사 결과 모든 시료에서 monocrotophos와 EPN이 검출되지 않았다. Monocrotophos와 EPN은 색달동과 대포동에서의 해수와 저니토에서도 검출되지 않았으며, 이러한 결과는 7월, 8월에서도 동일하였다. 따라서 남제주도 중문골프장 근해 해양 환경 중에서는 monocrotophos와 EPN의 유기인계 농약오염은 없는 것으로 나타났다.