• Journal of Trauma and Injury
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• 제26권3호
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• pp.151-156
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• 2013

Purpose: Traumatic cervical SCI is frequently accompanied by dural tear and the resulting cerebrospinal fluid (CSF) leak after surgery can be troublesome and delay rehabilitation with increasing morbidity. This study evaluated the incidence of intraoperative CSF leaks in patients with traumatic cervical spinal cord injury (SCI) who underwent anterior cervical surgery and described the reliable management of CSF leaks during the perioperative period. Methods: A retrospective study of medical records and radiological images was done on patients with CSF leaks after cervical spine trauma. Results: Seven patients(13.2%) were identified with CSF leaks during the intraoperative period. All patients were severely injured and showed structural abnormalities on the initial magnetic resonance image (MRI) of the cervical spine. Intraoperatively, no primary repair of dural tear was attempted because of a wide, rough defect size. Therefore, fibrin glue was applied to the operated site in all cases. Although a wound drainage was inserted, it was stopped within the first 24 hours after the operation. No lumbar drainage was performed. Postoperatively, the patients should kept their heads in an elevated position and early ambulation and rehabilitation were encouraged. None of the patients developed complications related to CSF leaks during admission. Conclusion: The incidence of CSF leaks after surgery for cervical spinal trauma is relatively higher than that of cervical spinal stenosis. Therefore, one should expect the possibility of a dural tear and have a simple and effective management protocol for CSF leaks in trauma cases established.

• 대한물리의학회지
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• 제15권3호
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• pp.109-116
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• 2020

PURPOSE: The objective of this study was to provide a basis for the need to apply psychological factors-based rehabilitation programs to osteoarthritis patients by understanding how the limitations on the activities of osteoarthritis patients relate to the health-related quality of life and depression. METHODS: This study assessed 1,994 osteoarthritis patients from the 7th Korea National Health and Nutrition Examination Survey (KNHANES, 2016-2018). The subjects were divided into two categories: with activity limitation and without activity limitation. A Chi-square test and logistic regression analysis were conducted. RESULTS: The EQ-5D index of subjects with activity limitation was .84 ± .16, it was .94 ± .12 in those with no activity limitation (p < .05). The diagnosis of depression was 16.8% and; 8.3% in those with and without activity limitation, respectively (p < .05). There was a significant difference in the odds ratio for each item in the EQ-5D. Moreover, the odds ratio for depression with an activity limitation was 2.171 (1.512 - 3.118) compared with no activity limitation. CONCLUSION: The activity limitation of osteoarthritis patients reduces the health-related quality of life significantly and increases the probability of depression. Therefore, the treatment of osteoarthritis patients should be approached considering the psychological conditions. Moreover, early diagnosis of depressive symptoms is needed to prevent symptom deterioration and increase the compliance with rehabilitation therapy.

• Annals of Clinical Neurophysiology
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• 제16권2호
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• pp.62-69
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• 2014

Background: Neuromodulation therapy has been used to an adjunctive treatment promoting motor recovery in stroke patients. The objective of the study was to determine the effect of repetitive transcranial magnetic stimulation (rTMS) on neurobehavioral recovery and evoked potentials in rats with middle cerebral artery occlusion. Methods: Seventy Sprague-Daley rats were induced permanent middle cerebral artery occlusion (MCAO) stroke model and successful stroke rats (n=56) assigned to the rTMS (n=28) and sham (n=28) group. The 10 Hz, high frequency rTMS gave on ipsilesional forepaw motor cortex during 2 weeks in rTMS group. The somatosensory evoked potential (SSEP) and motor evoked potential (MEP) were used to evaluate the electrophysiological changes. Behavioral function of the stroke rat was evaluated by the Rota rod and Garcia test. Results: Forty rats ($N_{rTMS}=20;\;N_{sham}=20$) completed all experimental course. The rTMS group showed better performance than sham group in Rota rod test and Garcia test at day 11 (p<0.05) but not day 18 (p>0.05). The amplitude of MEP and SSEP in rTMS group was larger than sham group at day 18 (p<0.05). Conclusions: These data confirm that the high frequency rTMS on ipsilesional cerebral motor cortex can help the early recovery of motor performance in permanent middle cerebral artery stroke model and it may simultaneously associate with changes in neurophysiological activity in brain.

• 대한정형도수물리치료학회지
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• 제11권1호
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• pp.65-73
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• 2005

Osteoarthritis has been considered a disease of the elderly because it is uncommon before the age of 40 years and is seen in approximately 80% of United States citizens older than 65 years. general population on kuri city in korea revealed that prevalence of knee osteoarthritis is 10.2%, increasing with age. High level of physical activity in men and age, post-menopause and obesity in women can be risk factor. Osteoarthritis is no evidence that a acquired process initiated much earlier in life through mechanical, metabolic, genetic, or other origins. A high tibial osteotomy alters static lower extremity alignment thereby decreasing medial compartment loading. As well, conservative treatment strategies, such as knee braces and valgus heel wedges, affect lover limb mechanics and attempt to reduce medial compartment loading. It was hypothesized that valgus heel wedges and modified orthoses would shift the center of pressure laterally on the foot during level walking, reducing the moment arm of the adduction moment in the frontal plane, thereby resulting in a decrease in the knee adduction moment. In the 1980s, the effect of wearing a laterally wedged insole on osteoarthritic patients with a varus deformity of the knee was firsted, and since then, kinematic and kinetic analyses concerning this condition have mainly focused on a static standing position. Since the early 1990s, the beneficial effect of wearing a laterally wedged insole to treat osteoarthritis of the knee has also been reported in dynamic conditions, but these studies did not answer the question of the kinematic and kinetic mechanisms that resulted in the reduced symptoms in patents with knee osteoarthritis. therefore, the effect of wearing laterally wedged insole has not been sufficiently studied.

• 한국콘텐츠학회논문지
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• 제16권12호
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• pp.327-345
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• 2016

본 연구는 인간발달 과정을 신경과학, 심리학, 운동학습, 근육 생리학 등의 행동과학 자료와 생체역학, 인체운동 분석, 운동조절 기반의 인지 동작치료 프로그램을 정서 행동장애 아동들에게 실시하여 표정에 따른 얼굴 움직임이 감정과 정서변화에 따라 어떤 특성을 갖는지를 표정 움직임의 변화로 정량화 하고자 하였다. 본 연구에서는 영상측정 및 키네마틱 분석의 정서 행동장애 아동의 표정변화를 중재 프로그램 피드백 자료로 활용하였고, 표정 변화를 통해 인지동작 치료프로그램 효과를 알 수 있었다. 또한 정서 및 행동치료의 영상분석과 키네마틱 분석의 정량적 데이터를 통하여 인간발달에 대한 융 복합적 측정 및 분석법을 적용하여 발달장애의 조기발견과 치료과정에 따른 데이터를 축적하는 것도 기대할 수 있었다. 따라서 본 연구의 결과는 아동뿐만이 아니라 자기표현이 부족한 장애와 노인, 환자에게도 확대 적용할 수 있을 것이다.

• The Journal of Korean Physical Therapy
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• 제33권5호
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• pp.231-237
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• 2021

Purpose: This study sought to investigate the effects of robot-assisted gait training on balance in total hip arthroplasty (THA) patients after bilateral avascular necrosis (AVN). Methods: This case study in two patients utilized an 'A-B-A' single-subject experimental design that included five days of pre-intervention, followed by five days of intervention, and five days of post-intervention. The intervention involved the use of a standing inclined robot (R-bot) for 15 minutes. The outcome measures were evaluated using the Functional Reaching Test (FRT), Time Up to Go (TUG), and the Modified One Leg Standing Test (OLST). Results: Patient 1 showed improvement based on data gathered from baseline A to intervention period B, with results as follows: FRT improved from 27.7 cm to 41.28 cm, OLST LT from 14.03 seconds to 67.37 seconds, OLST RT from 2.94 seconds to 35.97 seconds, and TUG from 12.96 seconds to 7.82 seconds. Patient 2 also showed improvement from baseline A to intervention period B, with results as follows: FRT improved from 17.18 cm to 24.3 cm, OLST LT from 11.53 seconds to 52.01 seconds, OLST RT from 12.99 seconds to 62.19 seconds, and TUG from 27.31 seconds to 12.99 seconds. Conclusion: Based on the results of this study, robotic rehabilitation during the early stages after surgery is effective for promoting balance in patients who have undergone THA due to bilateral AVN.

• 동의신경정신과학회지
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• 제32권3호
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• pp.285-302
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• 2021

Objectives: To examine the effect of long-term Korean medicine treatment on mild cognitive impairment (MCI). Methods: This study was conducted on two patients who were diagnosed with mild cognitive impairment and received long-term Korean medicine treatment. In order to evaluate the degree of cognitive decline, SNSB and K-MMSE were performed 2~3 times at the first visit and during the treatment process. Results: Both cases 1 and 2 were diagnosed with MCI with a high possibility of developing dementia. In case 1, MCI progressed to early dementia at one year after the diagnosis of MCI. However, in case 2, that MCI status was maintained without progressing to dementia for 4 years after the diagnosis of MCI. The cause of such difference in the course of MCI might be attributed to the fact that Case 1 had lower K-IADL level but higher SGDS level than Case 2 at the time of initial diagnosis, with weak family support and irregular herbal medicine intake. Conclusions: Korean medicine treatment could improve and manage symptoms of cognitive decline due to MCI.

• 한방재활의학과학회지
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• 제29권2호
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• pp.91-99
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• 2019

Objectives The loss of maternal care during early postnatal period may increase development of mood-related disorders, such as depression, anxiety, and personality disorders. In this study, the effect of acupuncture on depression in relation with cell proliferation in the hippocampal gyrus dentatus was investigated using maternal-separated rat pups. Methods On the postnatal 14th day, rat pups from six dams were grouped into following groups: maternal care group, maternal separation group, maternal separation and non-acupoint-acupunctured group, maternal separation and Zusanli-acupunctured group, and maternal separation and fluoxetine-treated group. Acupuncture was performed from postnatal 28th day to postnatal 37th day. The rat pups that belong in the maternal separation and fluoxetine-treated group were injected subcutaneously with 5 mg/kg fluoxetine hydrochloride once a day for the same period of time. To evaluate activity of the rat pups, open field test was performed. Immunohistochemistry for serotonin (5-hydroxytryptamine, 5-HT) and tryptophan hydroxylase (TPH) in the dorsal raphe and for 5-bromo-2'-deoxyuridine (BrdU) in the hippocampal gyrus dentatus was conducted. Results The present results reveal that the activity was decreased by maternal separation. In contrast, acupuncture at Zusanli overcame maternal separation-induced hypoactivity. Maternal separation suppressed TPH expression and 5-HT synthesis in the dorsal raphe and decreased cell proliferation in the hippocampal gyrus dentatus of rat pups. In contrast, acupuncture at Zusanli alleviated maternal separation-induced decrease of 5-HT synthesisand TPH expression. Conclusions The present results demonstrate that acupuncture at Zusanli ameliorated depressive state through increasing cell proliferation and enhancing 5-HT synthesis.

• 디지털융복합연구
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• 제17권2호
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• pp.283-292
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• 2019

초기의 인지 감퇴를 판단하는 요소로 의미지식 및 의미 연관관계의 범주별 손상 유무가 주목을 받고 있다. 본 연구에서는 정상 및 주관적 기억장애, 경도인지장애 노인을 대상으로 의미연상과제를 사용하여 인지 감퇴의 정도에 따라 관찰되는 의미 하위범주별 수행과 오류유형의 차이를 살펴보고자 하였다. 연구 결과, 의미연상과제 범주별 정반응 점수와 반응시간에서 세 군 간 유의한 차이를 보였으며, 하위범주 중, '기능'에서 가장 높은 수행력을, '상위'와 '부분/전체'에서 가장 낮은 수행력을 보였다. 또한, 오류유형별 산출 횟수는 정상에서 경도인지장애 노인으로 갈수록 유의하게 높아졌으며, 무반응은 주관적 기억장애 노인부터 유의하게 증가하였다. 결론적으로, 인지 감퇴가 진행될수록 의미연결망에서 범주별 손상의 정도와 과정이 다르므로, 기억장애 노인의 인지적 감퇴를 확인하고 추적 관찰하기 위한 지표로 의미연상과제 수행력을 활용할 수 있을 것이다.

• 대한정형외과학회지
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• 제55권2호
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• pp.103-116
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• 2020

회전근 개 파열은 인구의 고령화 및 영상 진단의 발전 등으로 인해 그 빈도가 빠르게 증가하고 있다. 최근에는 관절경적 봉합술이 일반화되어 있으며 수술 결과 역시 관혈적 봉합술과 대등한 유합률을 보이고 있다. 관절경적 수술 자체가 최소 침습적 방법이므로 수술 후 통증 감소와 조기 기능 향상이라는 부가적인 이점을 가질 수 있지만 최근에는 견관절의 관절경 수술 후 환자의 기능 회복을 더욱 향상시키기 위한 다양한 방법에 대한 관심이 높아지고 있다. 견관절 관절경 수술 후 기능 회복 치료 방법들은 수술 후 시기별로 나누어져 있으며 각 단계별로 활발히 연구되고 개선되고 있다. 그러나 각 시기별, 재활 단계별, 환자 개개인의 특성, 회전근개 파열의 정도 및 기저 질환에 따라 다양한 방법들이 많아 관절경적 회전근 개 봉합술 후 정상 견관절 상태로의 기능 회복을 위해 각 시기에 맞는 적합한 견관절의 기능 회복 방법에 대한 확립이 필요하다고 할 수 있다.