• PNF and Movement
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• 제16권2호
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• pp.239-248
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• 2018

Purpose: This study aimed to examine the elderly physical fitness test for elderly people living in urban areas and to evaluate the physical fitness level according to gender and age groups. Methods: The subjects were 180 elderly people aged 65 and over living in urban areas. The elderly people were classified into early old age, middle old age, and advanced old age groups. Five items of the physical fitness test for the elderly (arm curl, chair stand, 2 min step test, back scratch, and chair sit and reach). Results: In analyzing the average of each item by gender and age, a significant difference was found in the results of each item as age increased in all sports, but no difference was observed according to gender except dumbbell lifting. Conclusion: Although the physical fitness level of all ages decreased from early age to late age, the difference in physical fitness according to gender was not significant except the arm curl test. The results of this study can be used as basic data for a new "age-specific exercise program" for the elderly.

• 대한족부족관절학회지
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• 제19권3호
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• pp.81-85
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• 2015

Acute sprain of the ankle requires comprehensive history taking and physical examination in diagnosing the type of severity and deciding on the plan of treatment. Literature supports functional treatment as the treatment of choice for grade I and II injuries. During the acute phase, the goal of treatment focuses on controlling pain and swelling. PRICE (protection, rest, ice, compression, and elevation) is a well-established protocol at this phase. There is some evidence that application of ice and use of nonsteroidal anti-inflammatory drugs improves healing and speeds recovery. Then the functional treatment (motion restoration and strengthening exercises) is administered to progress the rehabilitation appropriately in order to facilitate healing and restore the mechanical strength and proprioception. Early mobilization has been shown to result in more rapid return to work and daily activities than immobilization. Grade III injuries still generate controversy in terms of the best management available, and more studies on early mobilization, cast immobilization, or surgery are needed. Even the Cochrane reviews published to date are not conclusive.

• Clinics in Shoulder and Elbow
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• 제8권2호
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• pp.135-140
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• 2005

Purpose: To find out the early results after surgical treatment of the acute acromioclavicular dislocation with LIGASTIC artificial ligament. Material and Method: 6 patients who were diagnosed as acute acomioclavicular joint dislocation and treated with LIGASTIC artifical ligament through March 2005 to July 2005. The radiologic and clinical results using Imatani evaluation system were analyzed. Results: By clinical evaluation, 4 cases(67%) were excellent and 2 cases(33%) were good. By radiologic evaluation, 3 cases(50%) were excellent and 3 cases(50%) were good. All cases showed satisfactory results. Till the final follow up, there were no complication. Conclusion: Surgical treatment of the acute acromioclavicular dislocation with LIGASTIC articifial ligament is simple, but provides enough stability for early postoperative rehabilitation, decreases arthritis of acomioclavicular joint and there is no burden of removal of the fixture, so it is thought as a very effective surgery.

• 국제물리치료학회지
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• 제11권1호
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• pp.1969-1974
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• 2020

Background: Early rehabilitation after partial meniscectomy is important to recover the balance of the vastus medialis oblique and vastus lateralis and prevent pathological problems in the lower extremities and the whole body. Objective: To compare muscle activations for patients after partial meniscectomy. Design: Dual-group Pretest-Posttest Design from the Quasi-Experimental Research. Methods: Twenty participants after partial meniscectomy were recruited and were randomly divided into a Q-setting sensorimotor training group (QSMTG) and Q-setting exercise group (QSEG). Muscle activity of the vastus medialis oblique and vastus lateralis was measured before and after intervention. Results: In the two groups, the vastus medialis oblique and vastus lateralis activations increased significantly (P<.05). The Q-setting sensorimotor training group showed more increases than the Q-setting exercise group, and there were significant differences between the groups (P<.05). The activation ratio of the vastus medialis oblique and vastus lateralis had increasingly significant differences in the Q-setting sensorimotor training group (P<.05), and there were no significant differences between the groups (P>.05). Conclusion: Q-setting exercise with sensorimotor training was a useful method that improved the balance of vastus medialis oblique (VMO) and vastus lateralis (VL) activity after meniscectomy.

• Journal of Genetic Medicine
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• 제15권2호
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• pp.110-114
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• 2018

Ataxia-telangiectasia (AT; OMIM 208900) is a rare autosomal recessive inherited progressive neurodegenerative disorder, with onset in early childhood. AT is caused by homozygous or compound heterozygous mutations in ATM (OMIM 607585) on chromosome 11q22. The average prevalence of the disease is estimated at 1 of 100,000 children worldwide. The prevalence of AT in the Republic of Korea is suggested to be extremely low, with only a few cases genetically confirmed thus far. Herein, we report a 5-year-old Korean boy with clinical features such as progressive gait and truncal ataxia, both ankle spasticity, dysarthria, and mild intellectual disability. The patient was identified as a compound heterozygote with two novel genetic variants: a paternally derived c.5288_5289insGA p.(Tyr1763*) nonsense variant and a maternally derived c.8363A>C p.(His2788Pro) missense variant, as revealed by next-generation sequencing and confirmed by Sanger sequencing. Based on claims data from the Health Insurance Review and Assessment Service Republic of Korea, we calculated the prevalence of AT in the Republic of Korea to be about 0.9 per million individuals, which is similar to the worldwide average. Therefore, we suggest that multi-gene panel sequencing including ATM should be considered early diagnosis.

• Mycobiology
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• 제51권1호
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• pp.1-15
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• 2023

Wound care has become increasingly important over the years. Various synthetic products for wound care treatment have been reported to cause toxic side effects and therefore natural products are in significant demand as they have minimal side effects. The presence of bioactive compounds in medicinal mushrooms contributes to various biological activities which assist in the early inflammatory phase, keratinocyte proliferation, and its migration enhancement which are pertinent to wound rehabilitation. Lignosus rhinocerus (tiger milk mushroom) can reduce the inflammation phase in wound healing by fighting off bacterial infection and modulating pro-inflammatory cytokines expression in the early stage to avoid prolonged inflammation and tissue damage. The antibacterial, immunomodulating, and anti-inflammatory activities exhibited by most macrofungi play a key role in enhancing wound healing. Several antibacterial and antifungal compounds sourced from traditional botanicals/-products may prevent further complications and reoccurrence of injury to a wounded site. Scientific studies are actively underway to ascertain the potential use of macrofungi as a wound healing agent.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.1059-1066
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• 2022

In 2020, it was estimated that more than 2.4 million households in South Korea are over 30 years old. That is, more than 40% of all houses in Korea are old and that they require proper rehabilitation. The two options to improve poor living conditions are reconstruction and remodeling. Compared to reconstruction, remodeling has advantages in terms of the construction period, cost, and environmental impact. As such, the current Korean regulations are more favorable for remodeling than reconstruction. Typically, several candidate floor plans are presented in the early stages of an apartment remodeling project. Extracting information about bearing walls and other structural elements from the multiple plans to compare those plans quantitatively is one of the essential tasks during the early stage of a project. To cope with this task, an automated data extraction method for walls and slabs from before and after remodeling plans is developed. Through the developed program, load-bearing walls, non-bearing walls, slabs, and weight changes after remodeling can be analyzed and visualized in a fast and automated manner.

• IMMUNE NETWORK
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• 제20권3호
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• pp.23.1-23.20
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• 2020

Sepsis is conceptually defined as life-threatening organ dysfunction that is caused by a dysregulated host response to infection. Although there has been significant advancement in recent decades in defining and understanding sepsis pathology, clinical management of sepsis is challenging due to difficulties in diagnosis, a lack of reliable prognostic biomarkers, and treatment options that are largely limited to antibiotic therapy and fundamental supportive measures. The lack of reliable diagnostic and prognostic tests makes it difficult to triage patients who are in need of more urgent care. Furthermore, while the acute inpatient treatment of sepsis warrants ongoing attention and investigation, efforts must also be directed toward longer term survival and outcomes. Sepsis survivors experience incomplete recovery, with long-term health impairments that may require both cognitive and physical treatment and rehabilitation. This review summarizes recent advances in sepsis prognosis research and discusses progress made in elucidating the underlying causes of prolonged health deficits experienced by patients surviving the early phases of sepsis.

• Tuberculosis and Respiratory Diseases
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• 제44권5호
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• pp.1040-1050
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• 1997

연구배경 : 만성폐쇄성폐질환 환자의 치료에 널리 적용되고 호흡재활치료는 폐기능을 호전시키지는 못하지만 호흡곤란 등의 증상과 운동능력을 호전시키는 것으로 알려져 있다. 그러나 이런 운동능력 개선의 기전은 여러 각도에서 해석되고 있다. 저자들은 $^{31}P$ MRS를 이용하여 만성 폐질환 환자들을 호흡재활치료 전후 전박근의 대사 변화를 관찰함으로써, 호흡재활치료 후 운동능력호전에 골격근 대사개선을 기여할 가능성을 조사하였다. 방 법 : 총 9명의 만성 폐질환을 갖고 있는 남자 환지들을 대상으로 하였고 이들의 평균 연령은 $58{\pm}11$세였으며, 이들의 기저 질환은 만성폐쇄성폐질환 8예 및 폐유육종증 1예였다. 호흡재활치료는 근육강화운동, 답차운동(treadmill walking), 자전거 운동(stationary bicycle riding) 및 상지 운동력측정계(arm ergometer)를 이용한 상지운동으로 구성했으며, 호흡재활치료 전후로 폐기능 검사, 운동부하 검사, 상하지의 지구력 측정 및 6분 보행거리 검사를 실시하였다. $^{31}P$ MRS검사를 치료 전후 전박근을 대상으로 안정시, 운동시 및 20분간의 회복시에 시행하여 세포내 산소성 인산화 능력을 반영하는 Pi/PCr의 비와 pHi(intracellular pH)를 구하여 비교하였다. 결 과 : 호흡재활치료 후 환자의 폐기능과 가스 교환의 호전은 없었으나, 운동지구력 및 보행능력은 현저한 호전을 보였으며 최대산소섭취량은 증가하는 경향을 보였고, 동 운동량에서의 분당환기량은 감소하는 경향을 나타내었다. $^{31}P$ MRS를 이용하여 재활치료 전후의 골격근 대사를 비교해 본 결과, 치료 후 운동시 및 극심한 피로상태에서의 pHi는 유의하게 높았고 산소성 인산화 과정을 반영하는 지표인 Pi/PCr는 감소하는 경향을 보였으나 안정시 및 회복기의 골격근 대사과정은 변화가 없었다. 결 론 : 이상으로 만성 폐질환 환자에서 6주간의 호흡재활치료는 운동지구력 및 보행 호전시켰으며 이러한 운동능력 호전에는 골격근 대사의 개선으로 초래된 골격근 세포내의 산성화 지연으로 인한 환기량의 감소가 기여할 사료되었다.

• Journal of Gastric Cancer
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• 제20권3호
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• pp.267-276
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• 2020

Purpose: The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) risk calculator is useful in predicting postoperative adverse events. However, its accuracy in specific disorders is unclear. We validated the ACS NSQIP risk calculator in patients with gastric cancer undergoing curative laparoscopic surgery. Materials and Methods: We included 207 consecutive early gastric cancer patients who underwent laparoscopic gastrectomy between January 2018 and January 2019. The preoperative characteristics and risks of the patients were reviewed and entered into the ACS NSQIP calculator. The estimated risks of postoperative outcomes were compared with the observed outcomes using C-statistics and Brier scores. Results: Most of the patients underwent distal gastrectomy with Roux-en-Y reconstruction (74.4%). We did not observe any cases of mortality, venous thromboembolism, urinary tract infection, renal failure, or cardiac complications. The other outcomes assessed were complications such as pneumonia, surgical site infections, any complications requiring re-operation or hospital readmission, the rates of discharge to nursing homes/rehabilitation centers, and the length of stay. All C-statistics were <0 and the highest was for pneumonia (0.65; 95% confidence interval: 0.58-0.71). Brier scores ranged from 0.01 for pneumonia to 0.155 for other complications. Overall, the risk calculator was inconsistent in predicting the outcomes. Conclusions: The ACS NSQIP surgical risk calculator showed low predictive ability for postoperative adverse events after laparoscopic gastrectomy for patients with early gastric cancer. Further research to adjust the risk calculator for these patients may improve its predictive ability.