• Journal of Korean Academy of Nursing
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• v.31 no.5
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• pp.921-931
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• 2001

The purpose of this study was to investigate the rate of pregnancy, abortion, delivery and contraceptive use and the relationship between the related factors and the early coitus among Korean teenagers. Method: The subjects of this study were 12,733 teenagers age 13-19 years in 7 major cities and 9 provinces in Korea. Data was collected from 2 Oct., to 28 Oct., 2000 and analyzed by using SPSS 10.0 Program. Results: The results showed pregnancy rate 4.5%, delivery rate 0.5%, abortion rate 0.4%. Adolescent girls who experienced coitus relatively went to vocational school, coeduaction school, night school in the general characteristics (p=0.000). Adolescent girls who experienced coitus tend to go to video room (18.5%), go the singing room (60.7%), the bar (54.8%), petting with the partner during the dates. There were overlapping juvenile delinquencies such as drinking (89.2%), pornography (65.3%), bond inhalation (2.7%), leaving homes (43.7%), smoking (14.5%), cyber sex (70.8%), phone sex (12.9%). Adolescent girls who experienced coitus were more suffering from Wangtta (26.1%) than who had not. They showed significant positive attitudes toward coitus; such as feeling of excitement (6.6%), nature (37.9%), beauty (8.7%). On the other hand, they had more guilty (2.8%) than the inexperienced (p=0.000). The main factors relating to early coitus were 'to confirm love' (46.9%), 'afraid of rejection' (32.2%). They think the benefits of coitus were 'more intimacy with boyfriends' (20.6%), 'satisfaction of curiosity' (16.8%). The losses on coitus were 'worry about pregnancy' (73.7%) and 'unability to refuse sexual contacts' (28.7%) Conclusion: It could be concluded that it is necessary to plan different sex education programs according to general characteristics and delinquency behaviors of teenage girls in Korea.

• Biomolecules & Therapeutics
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• v.30 no.4
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• pp.320-327
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• 2022

Neurodevelopmental disorders are complex conditions that pose difficulty in the modulation of proper motor, sensory and cognitive function due to dysregulated neuronal development. Previous studies have reported that an imbalance in the excitation/inhibition (E/I) in the brain regulated by glutamatergic and/or GABAergic neurotransmission can cause neurodevelopmental and neuropsychiatric behavioral deficits such as autism spectrum disorder (ASD). NMDA acts as an agonist at the NMDA receptor and imitates the action of the glutamate on that receptor. NMDA however, unlike glutamate, only binds to and regulates the NMDA receptor subtypes and not the other glutamate receptors. This study seeks to determine whether NMDA administration in mice i.e., over-activation of the NMDA system would result in long-lasting behavioral deficits in the adolescent mice. Both gender mice were treated with NMDA or saline at early postnatal developmental period with significant synaptogenesis and synaptic maturation. On postnatal day 28, various behavioral experiments were conducted to assess and identify behavioral characteristics. NMDA-treated mice show social deficits, and repetitive behavior in both gender mice at adolescent periods. However, only the male mice but not female mice showed increased locomotor activity. This study implies that neonatal exposure to NMDA may illicit behavioral features similar to ASD. This study also confirms the validity of the E/I imbalance theory of ASD and that NMDA injection can be used as a pharmacologic model for ASD. Future studies may explore the mechanism behind the gender difference in locomotor activity as well as the human relevance and therapeutic significance of the present findings.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.32 no.4
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• pp.129-136
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• 2021

Objectives: To investigate the relationship between brain structure and empathy in early adolescents with attention-deficit/hyperactivity disorder (ADHD). Methods: Nineteen early adolescents with ADHD and 20 healthy controls underwent 3T MRI. All the participants were assessed for different aspects of empathy using measures including the Interpersonal Reactivity Index and Empathy Quotient. Cortical thickness and subcortical structural volume based on T1-weighted scans were analyzed using FreeSurfer. Results: Cognitive empathy (t=-2.52, p=0.016) and perspective taking (t=-2.10, p=0.043) were impaired in the ADHD group compared with the control group. The cluster encompassing the left posterior insular, supramarginal, and transverse temporal cortices [cluster-wise p-value (CWP)=0.001], which are associated with emotional empathy, was significantly smaller in the ADHD group, and the volume of the left nucleus accumbens was greater than that of the control group (F=10.12, p=0.003, effect size=0.22). In the control group, the left superior temporal (CWP=0.002) and lingual cortical (CWP=0.035) thicknesses were positively associated with cognitive empathy, while the right amygdala volume was positively associated with empathic concern (Coef=14.26, t=3.92, p=0.001). However, there was no significant correlation between empathy and brain structure in the ADHD group. Conclusion: The ADHD group had a smaller volume of the cortical area associated with emotional empathy than the control group, and there was no brain region showing significant correlation with empathy, unlike in the control group.

• Journal of Korean Academy of Nursing
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• v.48 no.2
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• pp.232-240
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• 2018

Purpose: The aim of this study is to identify the types of gambling among adolescents and provide basic prevention information regarding adolescents' gambling problems. Methods: Secondary data from representative national survey on 2015 Youth Gambling Problems of Korea Center on Gambling Problems were used. Using latent class analysis (LCA), 13 gambling types such as offline and online games of 14,011 adolescents were classified, and gambling experiences and characteristics were analyzed. Results: The subgroups of adolescent gambling were identified as four latent classes: a rare group (84.5% of the sample), a risk group (1.0%), an offline group (11.9%), and an expanded group (2.6%). The types and characteristics of gambling among the latent classes differed. In the risk group, adolescents participated in online illegal sports betting and internet casino, and gambling time, gambling expenses, and the number of gambling types were higher than other groups. Conclusion: Gambling frequently occur among adolescent, and the subtypes of gambling did not reveal homogeneous characteristics. In order to prevent adolescent gambling problems, it is a necessary to develop tailored prevention intervention in the nursing field, which is appropriate to the characteristics of adolescent gambling group and can help with early identification.

• Nutrition Research and Practice
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• v.17 no.4
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• pp.780-788
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• 2023

BACKGROUND/OBJECTIVES: This study examined the relationship between famine exposure in early life and the risk of type 2 diabetes in adulthood during the 1959-1961 Chinese Famine. SUBJECTS/METHODS: A total of 3,418 individuals aged 35-74 years free of diabetes from two studies in 2006 and 2009 were followed up prospectively in 2009 and 2012, respectively. Famine exposure was classified as unexposed (individuals born in 1962-1978), fetal exposed (individuals born in 1959-1961), child exposed (individuals born in 1949-1958), and adolescent/adult exposed (born in 1931-1948). A logistic regression model was used to assess the relationship between famine exposure and diabetes after adjustment for potential covariates. RESULTS: During a three-year follow-up, the age-adjusted incidence rates of type 2 diabetes were 5.7%, 14.5%, 12.7%, and 17.8% in unexposed, fetal-exposed, child-exposed, and adolescent/adult-exposed groups, respectively (P < 0.01). Relative to the unexposed group, the relative risks (95% confidence interval) for diabetes were 2.15 (1.29-3.60), 1.53 (0.93-2.51), and 1.65 (0.75-3.63) in the fetal-exposed, child-exposed, and adolescent/adult-exposed groups, after controlling for potential covariates. The interactions between famine exposure and obesity, education level, and family history of diabetes were not observed, except for the urbanization type. Individuals living in rural areas with fetal and childhood famine exposure were at a higher risk of type 2 diabetes, with relative risks of 8.79 (1.82-42.54) and 2.33 (1.17-4.65), respectively. CONCLUSIONS: These findings indicate that famine exposure in early life is an independent predictor of type 2 diabetes, particularly in women. Early identification and intervention may help prevent diabetes in later life.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.17 no.2
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• pp.91-97
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• 2006

The effects of the Attachment Promotion Therapy (APT) program for the autistic children were reviewed by 8 papers. The program was consisted with play activity centered mother-child interaction, educational activity for parents, lecture, video-feedback, and support. APT program was effective to improve the attachment behaviors and attachment security. And the mother's behaviors to her child became more child-centered, positively responsive, expressive supportively. Ninety six point seven percent of the mothers were satisfied with the APT program. They described that it was helpful to understand their children's developmental limitation and strength, to learn how to play with their children, to make supportive social network among the mothers, to minimize familial conflicts, and to make them much more comfortable with their children. They thought the APT Program was to be a steppingstone of the further educational program. APT program is an effective early intervention to promote social development and decrease autistic problems.

• Journal of Families and Better Life
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• v.33 no.1
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• pp.1-17
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• 2015

This study investigated how variables of internalizing and externalizing problematic behaviors change according to gender and as time passes by and how the variables influence adolescent problematic behaviors. The variables selected for the analysis are personal variables, parent variables, peer and school variables, and community variables. longitudinal data collected for 4 years from the Korea Youth Panel Survey(KYPS) were utilized for the analysis. Data were collected initially from 2,707 fifth grade elementary students in 2005 and they were traced until 2008. The final respondents were 2,448 students. The findings are as follows. Frist, the statistical significance was found in changes of problematic behavioral variables in terms of the gender difference. Second, variables, such as self-esteem and self-control are negatively correlated to the problematic behaviors and stress level is strongly positively correlated to the behaviors. Third, the study pressure and peer attachment level are correlated to the initial value of internalizing problematic behaviors. In conclusion, given that more statistical significances were found at initial values than the change rates among variables, early intervention is important in addressing adolescent problematic behaviors.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.24 no.1
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• pp.13-20
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• 2013

Neuroleptic malignant syndrome (NMS) is a severe iatrogenic complication of treatment with antipsychotic medication. The aim of this review is to provide the clinical characteristics and treatments of children and adolescents with NMS. Searches were conducted in Medline, Korean studies Information Service System (KISS), and Research Information Service System (RISS). Sixteen case reports and two review articles were selected in Medline, and two Korean cases reported in department of emergency medicine and pediatrics were selected from RISS. Heterogeneous and atypical presentations of NMS were observed in children and adolescents. Some noticeable differences were observed between adult patients and child patients with NMS. In addition, symptom presentations related to atypical antipsychotic agents differed from those of typical ones. In treatment, bromocriptine and benzodiazepine were recommended for management of symptoms. In particular, electroconvulsive therapy (ECT) was a useful treatment option. For prevention and early detection of NMS in children and adolescents, evaluation of risk factors and understanding of diagnostic features of NMS are very important.

• Journal of Nutrition and Health
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• v.25 no.5
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• pp.413-418
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• 1992

The prevalence of childhood and adolescents obesity at ages 6 to 17 in Seoul were investigated on 1992. The number of children and adolescents comprised of 3310 boys and 3270 girls. Obesity was defined as weight that exceeded the standard weighter for heigher and sex by more than 20%(relative weight>120%) The results were as follows : 1) The overall prevalence rate of childhood and adolescent obesity was 14.45% The prevalence rate of boys was 15.83% and that of girls was 13.06% on 1992. The overall difference of prevalence rate between boys and girls in significant(p<0.001) 2) The highest peak age is 11 years old. There were two peaks in the prevalence rate of obesity one is from 9 to 11 years old. the other is from 15 to 17 years old. 3) The prevalence rate of overweight that exceeded the standard weight by more than 20% to 29% was 8.62% by more than 30% to 49% was 5.58% and by more than 50% was 0.25% Our study suggests than the prevalence rate of obesity among the children and adolescent in Seoul, Korea is gradually increasing which will affect the future adult population. We feel it is needed further investigation to determine the causes of increasing rate of obesity and early establishment of preventive programs.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.34 no.1
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• pp.40-50
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• 2023

Objectives: This study examined the validity of the Childhood Autism Rating Scale, Second Edition (CARS-2) compared with the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2) in identifying autism spectrum disorder (ASD). Methods: A total of 237 children were tested using both the CARS-2 and ADOS-2. We examined the correlation using Pearson's correlation analysis. In addition, we used a receiver operating characteristic graph to determine the optimal standard version of the CARS-2 (CARS2-ST) cutoff score for ASD diagnosis using the ADOS-2. Results: The concurrent validity of the CARS2-ST was demonstrated by a significant correlation with the ADOS-2 (r=0.864, p<0.001). The optimal CARS2-ST cutoff scores were 30 and 28.5 for identifying autism and autism spectrum, respectively, based on the ADOS-2. Conclusion: We suggest a newly derived CARS2-ST cutoff score of 28.5 for screening ASD and providing early intervention.