• Journal of the Ergonomics Society of Korea
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• v.26 no.3
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• pp.35-43
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• 2007

This study aims at providing some basic material to be made use of for establishing plans through which one can reduce job-related stress, through conducting a survey on the sources of stress and then distinguishing its symptoms by the sources. As the methods of the study, we conducted a questionnaire survey of some selected medium enterprises' employees in the National Capital region and analysed the results. The questionnaire was designed by using the dynamic stress model of Cooper and Eaker and consisted of 85 questions to examine the sources of stress, the characteristics of personalities, and symptoms by each type of stress. The total valid respondents were 392 persons indicating 65.3% of the response rate. For analysing the results, a rating scale was used, and the reliability and validity were tested by using Cronbach's alpha coefficient. As the result of the study, those workers in medium enterprises were found to be put under much stress by responsibility, physical environment factors and career development factors and so on. As physical symptoms of job-related stress, eye fatigue, stiffness in their shoulders, headache, worry or anxiety, and waist ache presented most in the respondents. In addition, as behavioral symptoms, chronic fatigue was most indicated. In organizational symptoms, dissatisfaction about the company and lack of self-motivation for the job performance were found to show most. Moreover, the results indicated that the closer personalities to those appearing in persons mostly of type A they had, the more they were put under intensive stress by the vagueness of their roles and responsibility among all the job characteristics.

• Journal of Acupuncture Research
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• v.31 no.1
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• pp.159-165
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• 2014

Background and objectives : Social phobia is a nervous anxiety characterized by one or more constant fear in social activity or specific situation which causes serious damage to individual's social functions leading to chronic functional impairment when it is untreated. The objective of this study is to report a new finding of a possible subtype of social phobia according to a case survey and study of sufferers found via online support group. Methods : A single case review using survey and interview on patient was employed. Following a no-treatment baseline period for examination and interview, biweekly acupuncture treatment with interview for in-depth examination was delivered for 6months. Also, for in-depth investigation of peripheral vision phobia, survey questionnaire was done by the members of a Korean support group on on-line social group forum. Result : A new type of social phobia which has not yet been reported nor mentioned in any journals, namely called 'peripheral vision phobia' has been identified. Biweekly acupuncture treatment reached a comfort state of mental status on one case of patient with social phobia. Limitation : Due to the shift of environment on patient's part, the termination of the school session at where the phobia occur the most, the reoccurrence of the phobia is yet to be examined. Also, the generalization of the new type of phobia as a subtype only by reviewing one case alone with survey interview of on-line social group has limitation. Conclusion : The result of the case review suggests that 'peripheral vision phobia' is strictly concentrated on malfunctioning of peripheral vision without functional or organic hindrance of pupils or of any parts of eyes including eye muscles due to peripheral vision phobia. PVP is similar to social phobia and it may be a subtype of social phobia, however, since etiology, diagnosis, medical treatment methods are under researched, investigation is yet to be done.

• The Korean Journal of Zoology
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• v.24 no.3
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• pp.123-131
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• 1981

The purple $(pr^+)$ gene of Drosophila and its associated enzyme, sepiapterin synthase, were employed in a study of the relationship between ontogenic expression and the location of the gene in the genome, Enzyme assays performed at different developmental stages indicate the $T(Y:2)pr^c5, cn/pr^c4 cn$ flies (files in which $pr^+$ has been translocated and which exhibit variegation) have a reduced amount of enzyme activity as compared with both wild-type and $pr^1$ flies. This reduction in activity was not found in larval stages, which suggests that the inactivation process probably occurs in late larval or early pupal stages. Tryptophan pyrrolase, the enzyme system associated with vermilion $(v^+)$, was also examined for activity in different developmental stages of the fly. Genotype carrying a translocated $v^+$ shows a peak of tryptophan pyrrolase activity in late larval stages, whereas, Oregon-R exhibits the lowest activity at this period.

• Parasites, Hosts and Diseases
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• v.46 no.3
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• pp.157-164
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• 2008

Three Acanthamoeba isolates (KA/E9, KA/E17, and KA/E23) from patients with keratitis were identified as Acanthamoeba triangularis by analysis of their molecular characteristics, a species not previously recognized to be a corneal pathogen. Epidemiologic significance of A. triangularis as a keratopathogen in Korea has been discussed. Morphologic features of Acanthamoeba cysts were examined under a microscope with differential interference contrast (DIC) optics. Mitochondrial DNA (mtDNA) of the ocular isolates KA/E9, KA/E17, and KA/E23 were digested with restriction enzymes, and the restriction patterns were compared with those of reference strains. Complete nuclear 188 and mitochondrial (mt) 16S rDNA sequences were subjected to phylogenetic analysis and species identification. mtDNA RFLP of 3 isolates showed very similar patterns to those of SH621, the type strain of A. triangularis. 16S and 18S rDNA sequence analysis confirmed 3 isolates to be A. triangularis. 18S rDNA sequence differences of the isolates were 1.3% to 1.6% and those of 16S rDNA, 0.4% to 0.9% from A. triangularis SH621. To the best of our knowledge, this is the first report, confirmed by 18S and 16S rDNA sequence analysis, of keratitis caused by A. triangularis of which the type strain was isolated from human feces. Six isolates of A. triangularis had been reported from contaminated contact lens cases in southeastern Korea.

• Journal of Environmental Health Sciences
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• v.45 no.2
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• pp.154-163
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• 2019

Objectives: The hazardous heavy metal contents of cosmetics were investigated and the resulting values were compared by type of cosmetics: skin care preparations (SCP), hair preparations (HP), makeup preparations (MP), and eye makeup preparations (EMP). Methods: The hazardous heavy metal contents (Pb, As, Cd, Sb, Ni and Hg) were analyzed for 358 cosmetics products (187 SCP, 82 HP, 56 MP, and 33 EMP). Hg was measured by the amalgamation method, and other hazardous heavy metals were measured by inductively coupled plasma optical emission spectrometer (ICP-OES) after decomposition using the microwave method. Results: The mean contents of Pb, As, Cd, Sb, Ni, and Hg in cosmetics were 0.424, 0.068, 0.024, 0.398, $0.567{\mu}/g$, and Not Detected, respectively. All of the hazardous heavy metals were detected in most products, but below the recommended maximums of the Ministry of Food and Drug Safety. The level of Cd was the lowest at 14.8%, and Sb was the highest at 41.2%. Pb, Sb and Ni showed the highest mean value and detection rate in EMP. As, Cd, and Hg showed the highest in SCP, HP, and MP, respectively. Conclusion: Hazardous heavy metals were detected in most products. In particular, Pb, Sb, and Ni were broadly detected in EMP, meaning more stringent quality control is required.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.34 no.11
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• pp.95-104
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• 2018

Healthcare technology has been growing and fostering cooperation between industry, university and hospitals as growth engines in korea. So, the medibio research institutes in hospital have been constructed to promote research and industrialization centering on healthcare technology. The purpose of this study is to investigate the cases of research institutes in hospitals, and search the characteristics of building organization of medibio research laboratory facilities. Case study is investigated by floor plan, homepage and site visits about five research institutes selected in research-driven hospitals. The facility title and size of research laboratory is originated from site area and research building location. The building function include not only the research lab and business office reflecting on the development platform, and but assembly and meeting room in the ground level. Laboratory floor plans have three types, rectangular, rectangular+linear and linear type, one is traditional and efficient, the others are people and friendly. And building core types are correlated with lab space unit modules, single and double side core are shown in rectangular type. All the laboratories are open lab, composed with laboratory bench and research note writing desk facing the lab service and enclosed lab-support area. And they have communication space looking as warm and cozy common area for the innovation, convergence and collaboration. As the high risk of contamination and high standard for safety and security, equipment and facilities are well managed with biological environment including BSC, fume hood, PCR classification, eye washing and emergency shower.

• Journal of Korean Academy of Nursing
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• v.52 no.1
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• pp.24-35
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• 2022

Purpose: This study investigated the incidence and risk factors of cataract in people with diabetes mellitus (DM) using data from Ansan cohort of the Korean Genome and Epidemiology Study (KoGES). Methods: Data from a total of 329 patients with type 2 DM without cataract who participated in Ansan cohort of the KoGES from baseline survey (2001-2002) to fifth follow-up visit (2011-2012) were examined. The characteristics of the subjects were analyzed with frequency and percentage, and mean and standard deviation. Cataract incidence was measured as incidence proportion (%). For risk factors of cataract, hazard ratio (HR) and 95% confidence interval (CI) were obtained using the Cox proportional hazard model. Results: The cataract incidence over a 10-year follow-up period was 19.1% (15.1 in males and 25.8 in females), and mean age at the incidence of cataract was 63.48 years (61.58 years in males and 65.31 years in females). Age (HR=1.09, 95% CI=1.05-1.13) and HbA1c (HR=1.21, 95% CI=1.07-1.37) or the duration of DM (HR=1.05, 95% CI=1.00-1.09) were found to be independently associated with cataract development. Conclusion: Cataract development in people with DM is common, and its likelihood increases with age, HbA1c, and the duration of DM. Considering negative effect of cataract on their quality of life and economic burden, nurses should identify people with DM at a higher risk of cataract development, and plan individual eye examination programs to detect cataract development as early as possible.

• Clinical Nutrition Research
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• v.12 no.3
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• pp.169-176
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• 2023

Glucose transporter type 1 (GLUT1) deficiency syndrome (DS) is a metabolic brain disorder caused by a deficiency resulting from SLC2A1 gene mutation and is characterized by abnormal brain metabolism and associated metabolic encephalopathy. Reduced glucose supply to the brain leads to brain damage, resulting in delayed neurodevelopment in infancy and symptoms such as eye abnormalities, microcephaly, ataxia, and rigidity. Treatment options for GLUT1 DS include ketogenic diet (KD), pharmacotherapy, and rehabilitation therapy. Of these, KD is an essential and the most important treatment method as it promotes brain neurodevelopment by generating ketone bodies to produce energy. This case is a focused study on intensive KD nutritional intervention for an infant diagnosed with GLUT1 DS at Gangnam Severance Hospital from May 2022 to January 2023. During the initial hospitalization, nutritional intervention was performed to address poor intake via the use of concentrated formula and an attempt was made to introduce complementary feeding. After the second hospitalization and diagnosis of GLUT1 DS, positive effects on the infant's growth and development, nutritional status, and seizure control were achieved with minimal side effects by implementing KD nutritional intervention and adjusting the type and dosage of anticonvulsant medications. In conclusion, for patients with GLUT1 DS, it is important to implement a KD with an appropriate ratio of ketogenic to nonketogenic components to supply adequate energy. Furthermore, individualized and intensive nutritional management is necessary to improve growth, development, and nutritional status.

• Korean Journal of Human Ecology
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• v.12 no.1
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• pp.75-84
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• 2003

The objective of this paper was to analyse the foot type of female university students by the direct and indirect measure of foot and the measures of foot outline. The results were as follow: 1. The length and the width of foot were small and ankle slender and the modification of the big toe slight. 2. The analysis on the 16 measure items revealed five factors; the first factor was related to the width and girth of foot, the second one to the length of foot, the third one to the transformation of the little toe, the fourth one to the height of foot, the fifth one to transformation of the big toe. 3. The grouping on the shape of foot revealed three types. The inline angle of foot was the smallest in average in the type 1, while it appeared to be middle in the other types. The wider foot shapes were grouped as type 2 because their inline and outline angles of foot were the biggest in average. In the type 3, the big toe was curved a lot, since it was the largest in average. 4. From the naked eye measuring method, classification from which toe was popped-out told that Egyptian foot was 30.9%, Greek foot 27.9%. On the other hand, the instrumental method showed that Egyptian foot was 57.3%, Squared foot 35.3% and Greek foot 7.4%. 5. The result from the analysis about the traits of foot shape by the degree of the arch formation of bottom foot, showed that 33.8% had the normal foot, 66.2% slightly flat foot or middle one. There was no one with rigid flat foot. 6. The shoes size they declared were that 240cm was 33.3%, 235cm 18.1% and 245cm 18.1%. The shape of their shoe heel were flat heel(34.8%), cuban heel(25.5%), and narrow straight heel(19.9%); and that of the shoe toe were round toe(25.4%), oval toe(20.4%) and squared toe(20.4%). 7. The discomforting parts when they wear shoes were the little toe(35.4%), the rear of foot(13.9%), and the width of foot(13.9%), which was related to their dislike of shoe with the pointed toe.

• Journal of Aquaculture
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• v.10 no.2
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• pp.179-187
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• 1997

Early development growth and sexual phenomena of the hybrid between male spotted flounder (Verasper variegatus) and female olive flounder (Paralichthys olivaceus) were investigated. The hybrid produced was newly called the "Bumnupchi" in Korean name, "Mottled flounder" in English name. Fertilization rate, hatching rate and early survival rate of the mottled flounder were 56.9~72.3%, 86.7~92.5% and 89.1~96.0%, respectively. At 50th day and 240th day after hatching, they were 2.1$\pm0.2cm\;and\;22.9\pm2.1cm\;in\;total\;length, \;0.10\pm0.002g\;and\;179.0\pm38.5g$ in body weight, respectively. Eye position of the mottled flounder was mixed with both dextral (77.7%) and sinistral type (22.3%). Gonads were differentiated into ovarian type and testis type at 80th day after hatching, and its ratio was 1:1 (P>0.05). Most Gonads seemed to be sterile without having germ cell, whereas only 3.6% of investigated indiciduals turned out to have oocytes in the gonad. When the induction of sex reversal were attempted by daily oral administration of $17\beta$-methyltestosterone (0.5mg/kg fish) andestradiol-17$17\beta$(0.5mg/kg fish)from 40th to 100th day after hatching, both testis and ovary type were induced 81.9% and 87.7% of each hormone-treated fish, respectively.fish, respectively.