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Who Gets Government SME R&D Subsidy? Application of Gradient Boosting Model (Gradient Boosting 모형을 이용한 중소기업 R&D 지원금 결정요인 분석)

  • Kang, Sung Won;Kang, HeeChan
    • The Journal of Society for e-Business Studies
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    • v.25 no.4
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    • pp.77-109
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    • 2020
  • In this paper, we build a gradient Boosting model to predict government SME R&D subsidy, select features of high importance, and measure the impact of each features to the predicted subsidy using PDP and SHAP value. Unlike previous empirical researches, we focus on the effect of the R&D subsidy distribution pattern to the incentive of the firms participating subsidy competition. We used the firm data constructed by KISTEP linking government R&D subsidy record with financial statements provided by NICE, and applied a Gradient Boosting model to predict R&D subsidy. We found that firms with higher R&D performance and larger R&D investment tend to have higher R&D subsidies, but firms with higher operation profit or total asset turnover rate tend to have lower R&D subsidies. Our results suggest that current government R&D subsidy distribution pattern provides incentive to improve R&D project performance, but not business performance.

A STUDY ON THE PHYSICAL PROPERTIES OF GLASS IONOMER CEMENT FOR RESTORATIVE FILLING USING VISIBLE LIGHT POLYMERIZATION (가시광선중합화에 따른 충전용 Glass Ionomer Cement의 물리적 성질에 관한 연구)

  • Shin, Dong-Hoon;Kwon, Hyuk-Choon
    • Restorative Dentistry and Endodontics
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    • v.17 no.2
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    • pp.307-330
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    • 1992
  • The aim of this study was to investigate the physical properties of visible light curing Glass Ionomer cement for restorative esthetic filling. The control group was the autopolymerizing GC Fuji II Glass Ionomer cement (2.2: 1 P/L ratio) and the experimental groups were made by following procedure. To induce the polymerization by visible light, the powder of GC Fuji II GI cement and the liquid of Vitrabond for base & liner were mixed in an amalgam capsule with 2.5:1, 3.0:1, 3.5:1 P/L ratio (% wt/wt). After fabrication of specimens, compressive strength, fracture toughness ($K_{IC}$) Scanning Electron Microscope and X-ray Diffraction, water-leachable content, marginal leakage and surface roughness were studied. The results were as follows: 1. Only experimental No. 1 group (visible light curing) showed less compressive strength than control group 1 hour after curing. Strength was increased with aging in all groups, so the compressive strength of light curing groups was no less than that of autopolymerizing group after 3 weeks. 2. Experimental No.3 group (visible light curing) was inferior to No.2 group (visible light curing) in fracture resistance but light curing groups were more resistant to fracture than autopolymerizing group and showed ductile fracture pattern as compared with the brittle fracture pattern of autopolymerizing group. 3. From scanning electron microscopic image, various sized unreacted powder particles, surrounded by silica gel, were embedded in polysalt matrix. Light curing groups showed little crack and more dense unreacted particles than autopolymerizing group. 4. From X-ray diffraction analysis, GC Fuji II Glass Ionomer cement powder and all groups showed glassy appearance but light curing groups seemed to be more intensive in crystaline than autopolymerizing group. S. The most significant dissolution was shown in early setting period in all group. Light curing groups were dissolved less than autopolymerizing group. 6. Marginal leakage was not different significantly in case of cavity margin composed of same tooth structure (ex. only enamel margin, only dentin margin) but much more leakage was shown in dentin/cementum margin than enamel margin. In only case of only enamel margin, light curing groups were superior to autopolymerizing group. 7. All groups showed relatively smooth surface, which irregularity was less than $1{\mu}m$. Light curing groups were smoother than autopolymerizing group.

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2차원 중성자수송모델 합성법에 의한 노외계측기 교정법

  • 하창주;성기봉;이해찬;유상근;정선교;이덕중;김윤호;김용배
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.10a
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    • pp.335-341
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    • 1997
  • 운전중 노심의 출력변화를 감시하는 노외계측기(Excore Detector)는 노내계측기(Incore Detector)를 통하여 측정되어진 축방향 출력편차(Axial Offset)를 이용하여 교정되고 있다. 노외 계측기의 전류와 축방향출력편차의 선형적인 관계를 가정하여 노내계측기로 최소한 4회 노심출력을 측정한후 최소자승법(Least Square Method)으로 비례상수들을 구하는 기존의 방법을 대신하여, 단순 노외계측기 교정법은 노내계측기로 1회 측정되어진 자료들을 이용하여 계측기 반응상수(Detector Response Factor)를 계산한 후 비례상수를 계산한다. 계측기반응상수는 2차원 중성자수송모델로부터 계산된 weighting factor와 3차원 확산이론으로부터 구한 노심출력을 이용하여 계산된다. 중성자수송계산은 (R-Z)와 (R-$ heta$)모델을 합성하여 3차원 weighting factor를 계산하므로 축방향 영향뿐만 아니라 집합체별 영향을 고려하였다. 또한 노심의 복잡한 구조로 인하여 근사적인 weighting (actor와 노심출력분포의 사용은 노외계측기의 전류와 계측기반응율의 불일치를 초래하며, 이를 해결하는 상수를 소개하여 보다 정확한 교정결과를 얻도록하였다. 이와 같은 방법을 고리 3호기 9, 10주기 전주기와 11주기초에 적용하여 노심의 연소분포, 냉각수의 온도분포, 노심의 연소도, 노심출력준위등에 대한 단순 노외계측기 교정법의 오차를 분석하여 최적의 노외계측기 교정모델을 제시하였다. 2차원 중성자수송모델 합성법에 의한 단순노외계측기 교정법은 2차원 (R-Z) 중성자수송모델보다 개선된 결과와 평균오차 0.179% 최대 오차 0.624%를 보여주고 있다.하면 조사 후의 조직안정성에도 크게 기여할 것으로 기대된다.EX>O가 각각 첨가된 경우, Ar-4vol.%H$_2$ 분위기보다 H$_2$분위기에서 소결했을 때 밀도가 더 높았다. 그러나, 결정립은 $UO_2$$UO_2$-Li$_2$O의 경우, 수소분위기에서 소결했을 때, (U,Ce)O$_2$와 (U,Ce)O$_2$-Li$_2$O에서는 Ar-4vol.%H$_2$분위기에서 소결했을 때 더욱 성장하였다.설명해 줄 수 있다. 넷째, 불규칙적이며 종잡기 힘들고 단편적인 것으로만 보이던 중간언어도 일정한 체계 속에서 변화한다는 사실을 알 수 있다. 다섯째, 종전의 오류 분석에서는 지나치게 모국어의 영향만 강조하고 다른 요인들에 대해서는 다분히 추상적인 언급으로 끝났지만 이 분석을 통 해서 배경어, 목표어, 특히 중간규칙의 역할이 괄목할 만한 것임을 가시적으로 관찰할 수 있 다. 이와 같은 오류분석 방법은 학습자의 모국어 및 관련 외국어의 음운규칙만 알면 어느 학습대상 외국어에라도 적용할 수 있는 보편성을 지니는 것으로 사료된다.없다. 그렇다면 겹의문사를 [-wh]의리를 지 닌 의문사의 병렬로 분석할 수 없다. 예를 들어 누구누구를 [주구-이-ν가] [누구누구-이- ν가]로부터 생성되었다고 볼 수 없다. 그러므로 [-wh] 겹의문사는 복수 의미를 지닐 수 없 다. 그러면 단수 의미는 어떻게 생성되는가\ulcorner 본 논문에서는 표면적 형태에도 불구하고 [-wh]의미의 겹의문사는 병렬적 관계의 합성어가 아니라 내부구조를 지

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Transfection of Mesenchymal Stem Cells with the FGF-2 Gene Improves Their Survival Under Hypoxic Conditions

  • Song, Heesang;Kwon, Kihwan;Lim, Soyeon;Kang, Seok-Min;Ko, Young-Guk;Xu, ZhengZhe;Chung, Ji Hyung;Kim, Byung-Soo;Lee, Hakbae;Joung, Boyoung;Park, Sungha;Choi, Donghoon;Jang, Yangsoo;Chung, Nam-Sik;Yoo, Kyung-Jong;Hwang, Ki-Chul
    • Molecules and Cells
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    • v.19 no.3
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    • pp.402-407
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    • 2005
  • Bone marrow mesenchymal stem cells (MSCs) have shown potential for cardiac repair following myocardial injury, but this approach is limited by their poor viability after transplantation. To reduce cell loss after transplantation, we introduced the fibroblast growth factor-2 (FGF-2) gene ex vivo before transplantation. The isolated MSCs produced colonies with a fibroblast-like morphology in 2 weeks; over 95% expressed CD71, and 28% expressed the cardiomyocyte-specific transcription factor, Nkx2.5, as well as ${\alpha}$-skeletal actin, Nkx2.5, and GATA4. In hypoxic culture, the FGF-2-transfected MSCs (FGF-2-MSCs) secreted increased levels of FGF-2 and displayed a threefold increase in viability, as well as increased expression of the anti-apoptotic gene, Bcl2, and reduced DNA laddering. They had functional adrenergic receptors, like cardiomyocytes, and exposure to norepinephrine led to phosphorylation of ERK1/2. Viable cells persisted 4 weeks after implantation of $5.0{\times}10^5$ FGF-2-MSCs into infarcted myocardia. Expression of cardiac troponin T (CTn T) and a voltage-gated $Ca^{2+}$ channel (CaV2.1) increased, and new blood vessels formed. These data suggest that genetic modification of MSCs before transplantation could be useful for treating myocardial infarction and end-stage cardiac failure.

A Study on Korean Security association - In comparison with All Japan Security Service Association - (한국경비협회(韓國警備協會)의 활성화(活性化) 방안(方案) -한일경비협회(韓日警備協會)의 비교(比較)를 중심으로-)

  • Choi, Eun-Ha;Kim, Hak-Bu
    • Korean Security Journal
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    • no.15
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    • pp.317-336
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    • 2008
  • Thus in order to have a better understanding about the KSA(Korean Security association) and to express opinions on its role and security, this paper introduces and discusses about All Japan Security Service Association(AJSSA), which is the prototype of the KSA. There are several positive aspects to consider the introduction of, when these two associations are compared: the traffic security, a supporting member, ex-high-ranking police executive directors practically run AJSSA. These are to enhance financial ability and to promote better relationship with police. KSA needs to improve such relationship and to diversify activities as well. In addition, not just dismissing their duty by giving them the license, AJSSA provides several educations to revitalize the related people so that they can deal in effective and productive services. In another words, JSA perceives it is indispensable to educate the relevant people in the business. In contrast, it is reality that KSA has not put much emphasis on educations. Concisely, the most prompt issue is it should be more beneficial to its members by strengthening itself. Not simply following the example of foreign cases, but putting diverse efforts, KSA can make it substantial and stabilize future private security market in a long term.

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Floristic Study of Mt. Segeolsan in Korea (세걸산의 관속식물상)

  • Kim, Yoon-Young;Na, Nu-Ree;Song, Hye-In;Jang, Changgee
    • Korean Journal of Plant Resources
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    • v.29 no.1
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    • pp.110-127
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    • 2016
  • This floristic study was conducted from April to September, 2014 in 12 days. The investigated area was Mt. Segeolsan (1,261 m) which is the part of Chirisan National Park and its neighbor region, Goan-ri, Sandeuk-ri. Based on voucher specimens, flora of this area consisted of 108 families, 376 genera, 584 species, 5 subspecies, 73 varieties, and 16 forma, totally 679 taxa. 17 taxa were endemic to Korea such as Carex okamotoi Ohwi, Cimicifuga austrokoreana H.W. Lee & C.W. Park., Thalictrum rochebrunianum var. grandisepalum (H.Lév.) Nakai, Fallopia koreana B.U. Oh & J.G. Kim, Asarum patens (Yamaki) Yamaki ex Y.N. Lee, and Stewartia pseudocamellia Maxim. etc. Among these species, C. austrokoreana, T. rochebrunianum var. grandisepalum, F. koreana, A. patens are considered having a southern boundary line of distribution in the Chirisan National Park region. And so Carex okamotoi has main distribution center in the Chirisan National Park region, this study region is assumed important in phytogeography. The useful plants were 633 taxa, ethonobotanic plants were 359 taxa in this area. Invasive alien species were 61 taxa, which were naturalized rate (9.0%) and urbanized index (17.4%).

Effects of a Plant Water Extract Mixture(Ixeris sonchifolia Hance, Oenanthe javanica, Fagopyrum esculentum Moench, Hizikia fusiforme, Zingiber officinale Roscoe) on Mouse Immune Cell Activation (식물 혼합(고들빼기, 돌미나리, 메밀, 톳, 생강) 추출물이 마우스 면역 세포 활성에 미치는 영향)

  • Kim, Jung-Hee;Kim, Hyun-Sook;Ryu, Hye-Sook
    • The Korean Journal of Food And Nutrition
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    • v.20 no.1
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    • pp.74-78
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    • 2007
  • Ixeris sonchifolia Hance(Godulbaegi), Oenanthe javanica(Dolminari), Fagopyrum esculentum Moench(Buckwheat), Hizikia fusiforme(Seaweed Fusiforme) and Zingiber officinale Roscoe(Ginger) have all been used as one of the traditional remedies as well as food source. There are few studies However, on their immunomodulating effects have been reported. We previously reported that ex vivo supplementation of each of the Ish, Oj, Fem, Hf and Zor water extracts enhanced the splenocytes proliferation compared to the control group. In this study, the combined immunomodulative effects of a plant water extract mixture containing these five food sources(Ish+Oj+Fem+Hf+Zor) was compared to the individual effect of each. The production of cytokine(IL-1${\beta}$, IL-6, and TNF-${\alpha}$), secreted by macrophages stimulated with LPS or without, were detected via ELISA assay using a cytokine kit. After 48hrs of incubation with mitogen(ConA or LPS) stimulation, the mouse splenocyte proliferation in the experimental group had significantly increased at two different concentrations compared to the control group. The results of this study may suggest that the supplementing with a plant water extract mixture could regulate immune function by increasing splenocyte proliferation as well as enhance immune function by regulating the cytokine production capacity activated macrophages in mice.

Determination of Governing Law in International Commercial Arbitration (국제상사중재(國際商事仲裁)에서 준거법(準據法)의 결정(決定))

  • Oh, Won-Suk
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.29
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    • pp.39-61
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    • 2006
  • The governing law in international commercial arbitration may be divided into governing arbitration law and governing substantive law. The former governs the parties' arbitration agreement and the conduct of any subsequent arbitration. But the later governs the parties' substantive rights and obligations, which means the law that governs contract formation and performance, and the law to be applied by the arbitrator to the merits of the dispute. The purpose of this paper is to examine how to determine the substantive governing law when there is express choice or implied choice between parties. Moreover this author checked any restrictions on party autonomy and also any possibilities to deviate from the governing law. In case of express choice the sources of the law or rules of law might be the national law of one of the parties, the neutral law, the general principles of law or lex mercatoria according to the arbitration law selected by the arbitral tribunal. Some arbitration laws or rules empower the arbitrator to decide the case ex aequo et bono or to act as amiable compositions. If the governing law could be determined expressly or impliedly by the parties, the arbitral tribunal would make a selection. In this case the criteria for selecting a governing law are not exactly same from country to country. But failing any indication by the parties as to governing law, the arbitral tribunal should apply the rules of law, the law or the law under the rule of conflict that the arbitrators consider applicable, according to the governing arbitration law. Among the connecting factors offered by the conflict rules, (which means the factors that the arbitrators consider applicable), some legal systems give precedence to the formation of the contract, other system to the place of performance of the contract, and others to the closest connection or centre of gravity. But the Rome Convention, which unified the conflict rules of the contracting states, gives precedence to the law of the domicile of the party which has to effect the performance which is characteristic of the contract. Finally this author suggested the Choice of Law Clause which covers governing substantive law and governing arbitration law at the same time. Thus the UNIDROIT Principles as well as any national law may be included as a governing law in international arbitration. So when we make sales or service contract, we should take into consideration of the UNIDROIT Principles as a governing law or a supplement to the governing law.

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An Analysis of Fall Incidence Rate and Its Related Factors of Fall in Inpatients (입원환자 낙상 발생 실태와 원인에 관한 분석 연구)

  • Kim, Chul-Gyu;Suh, Moon-Ja
    • Quality Improvement in Health Care
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    • v.9 no.2
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    • pp.210-228
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    • 2002
  • Background: The purpose of this research was to examine the fall incidence rate and its related factors of fall in inpatients. Methods: The data were collected from the 138 fall incident reports in one tertiary hospital in Seoul from April 1st 1999 to September 30th 2001. The Fall Incident Report Form was originally developed based on that of Massachusetts General Hospital revised in 1995. And this was modified for this survey by the collaborating work of QI team including researcher and department of nursing service of this particular hospital. The contents of Fall Incident Form were general characteristics of patient. factors related to fall. types and places of fall. circumstances, nursing interventions. and outcome. Results: 1) The incidence rate of fall was 0.08% of total discharged patients and 0.081 per 1000 patient-day. This incidence rate is much lower than that of several hospitals in USA. This finding might result from the different incidence report system of each hospital. 2) The characteristics of fall-prone patient were found as follows. They were mostly over 60 years old, in alert mental status, ambulatory with some assistance, and dependent on ambulatory device. The types of diseases related high incidence rate were cerebrovascular disease(3.2), hypertension(1.6), cardiovascular disease(1.4), diabetes(1.3) and liver disease(0.6). 3) The majority of fall events usually occurred m bed. bedside(walking or standing) and bathroom in patient room. Usually they were up on their own when they fell. And there were more falls of elderly occurred during night time than day or evening. 4) 63.8% of fall events resulted in physical injuries such as fracture and usually the patients had diagnostic procedures and some treatment(ex. suture) which caused additional cost to the patients and their families. 5) The found risk factors of fall were drugs(antihypertensive drug, diuretics) and environmental factors like too high bed height, long distance of bedside table and lamp switch, and slippery tile of bathroom floor. Conclusion: Considering these results, every medical and nursing staff should be aware of the risk factors of patients in hospital, and should intervene more actively the preventive managements, specially for the elderly patients during night. Therefore, it is recommended that the development of Fall Prevention Programs based on these results.

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Examination of the Production of Extracellular $\alpha$-Amylase by Bacillus thuringiensis, 19 serotypes (Bacillus thuringiensis, 19 혈청형의 세포외 $\alpha$-Amylase 생산 검색)

  • 이건주;박동왕;이형환;이영주
    • Microbiology and Biotechnology Letters
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    • v.16 no.5
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    • pp.348-351
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    • 1988
  • The production of extracellular $\alpha$-amylase by Bacillus thuringiensis 19 serotypes was examined by the hydrolysis test of starch. Thirteen serotypes produced the amylase. B. thuringiensis serovar thuringiensis alesti, kurstaki, sotto, kenya, israelensis, morrisoni, entomocidus, tolworthi, thompsoni, toumanoffi, pakistani, and indiana produced tee enzyme. The amylase produced by B. thuringiensis serovar israelensis showed highest activity around pH 6.7 to 7.2 and 55$^{\circ}C$ to $65^{\circ}C$. The high production medium of the amylase was composed of 1% bactopeptone, 0.3% beef-extract, 0.3% yeast ex-tract, 0.5% NaCl, 0.3% $K_2$HPO$_4$, 0.1% KH$_2$PO$_4$, 0.2% Soluble Starch, 0.012% CaCl$_2$.2$H_2O$$_2$, 0.005% MnCl$_2$, and 0.03% MgCl$_2$.7$H_2O$. The highest production of the enzyme was observed at 4 hours culture in the soluble starch (0.6 units/$m\ell$) or glucose (0.43 units/$m\ell$) substrate.

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