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Dosimetric Characteristics of Multileaf Collimator-based Intensity-modulated Arc Therapy for Stereotactic Radiosurgery (방사선수술 시 다엽 콜리메이터를 기초로 한 IMAT의 선량분포)

  • Yun, Sang-Mo;Kim, Sung-Kyu
    • Progress in Medical Physics
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    • v.18 no.2
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    • pp.93-97
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    • 2007
  • This study was designed to evaluate radiosurgery technique using multiple noncoplanar arc therapy with intensity modulated fine MLC shaped photon beam. The stereotactic radiosurgery was performed with 6-MV X-ray beams from a Clinac 21EX LINAC (Varian, Palo Alto, CA, USA) with a MLC-120, which features a full $40{\times}40cm$ field and is the first MLC for general use that offers 0.5 cm resolution for high precision treatment of small and irregular fields. We used a single isocenter and five gantry-couch combinations with a set of intensity modulated arc therapy. We investigated dosimetric characteristics of 2 cm sized spherical target volume with film (X-OMAT V2 film, Kodak Inc, Rochester NY, USA) dosimetry within $25{\times}25cm$ acrylic phantom. A simulated single isocentric treatment using inversely Planned 3D radiotherapy planning system demonstrated the ability to conform the dose distribution to an spherical target volume. The 80% dose level was adequate to encompass the target volume in frontal, sagittal, and transverse planes, and the region between the 40% and 80% isodose lines was $4.0{\sim}4.5mm$ and comparable to the dose distribution of the Boston Arcs. We expect that our radiosurgery technique could be a treatment option for irregular-shaped large intracranial target.

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Growth of Graphene Films from Solid-state Carbon Sources

  • Kwak, Jinsung;Kwon, Tae-Yang;Chu, Jae Hwan;Choi, Jae-Kyung;Lee, Mi-Sun;Kim, Sung Youb;Shin, Hyung-Joon;Park, Kibog;Park, Jang-Ung;Kwon, Soon-Yong
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.181.2-181.2
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    • 2014
  • A single-layer graphene has been uniformly grown on a Cu surface at elevated temperatures by thermally processing a poly (methyl methacrylate) (PMMA) film in a rapid thermal annealing (RTA) system under vacuum. The detailed chemistry of the transition from solid-state carbon to graphene on the catalytic Cu surface was investigated by performing in-situ residual gas analysis while PMMA/Cu-foil samples being heated, in conjunction with interrupted growth studies to reconstruct ex-situ the heating process. We found that the gas species of mass/charge (m/e) ratio of 15 ($CH_3{^+}$) was mainly originated from the thermal decomposition of PMMA, indicating that the formation of graphene occurs with hydrocarbon molecules vaporized from PMMA, such as methane and/or methyl radicals, as precursors rather than by the direct graphitization of solid-state carbon. We also found that the temperature for dominantly vaporizing hydrocarbon molecules from PMMA and the length of time, the gaseous hydrocarbon atmosphere is maintained, are dependent on both the heating temperature profile and the amount of a solid carbon feedstock. From those results, we strongly suggest that the heating rate and the amount of solid carbon are the dominant factors to determine the crystalline quality of the resulting graphene film. Under optimal growth conditions, the PMMA-derived graphene was found to have a carrier (hole) mobility as high as ${\sim}2,700cm^2V^{-1}s^{-1}$ at room temperature, which is superior to common graphene converted from solid carbon.

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An analysis of the genetic diversity of a riparian marginal species, Aristolochia contorta (수변 경계종인 쥐방울덩굴의 유전적 다양성 분석)

  • Nam, Bo Eun;Park, Hyun Jun;Son, Ga Yeon;Kim, Jae Geun
    • Journal of Wetlands Research
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    • v.22 no.2
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    • pp.100-105
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    • 2020
  • Northern pipevine (Aristolochia contorta) commonly inhabits marginal areas between waterside and terrestrial vegetation. In particular, A. contorta is ecologically important in the marginal areas as a food plant of dragon swallowtail butterfly (Sericinus montela), which is designated as vulnerable species in the Republic of Korea. For long-term sustainability of the plant population, assessment of the genetic diversity of exist populations should be conducted. Genomic DNA of A. contorta leaf samples were extracted from four populations where the vigorous growth were observed in the South Korea. Intra-population genetic diversity and inter-population genetic distance were assessed using randomly amplified polymorphic DNA (RAPD) with five polymorphic random primers. Overall genetic diversity was lower, compared to other wetland species (h: 0.0607 ~ 0.1401; I: 0.0819 ~ 0.1759), while GP showed the highest intra-population genetic diversity. Despite of the geographical distance, GP showed the larger genetic distance from other populations. This result seemed to be caused by the fragmented habitat and lower sexual reproduction of A. controta. Mixture of the different source populations and construction of the proper environmental condition such as shade and physical support for sexual reproduction should be considered for conservation of A. contorta population.

A GINGIVAL MARGINAL FIT OF THE ADHESIVE CLASS II CAST GOLD INLAY (접착형 2급 주조 금 인레이의 치은변연 접합도에 관한 연구)

  • Choi, Hee-Kyung;Shin, Dong-Hoon;Hong, Chan-Ui
    • Restorative Dentistry and Endodontics
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    • v.19 no.2
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    • pp.473-484
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    • 1994
  • To investigate the effect of resin cement, which had been known to increase the adhesive capacity of the cast gold inlay, on the gingival marginal fit and whether the tin-planting of the beveled area affects the marginal fit, Class II cast gold inlays were made on the 25 sound molars. Control group(ZPC goup) was cemented with the ZPC by conventional method. Experimental groups were cemented with the resin cement(Super-hond & $Panavia_{EX}$) and subdivided further by the existence or nonexistence of the tin-plating of the beveled area(ST & PT groups: with plating, SNT & PNT groups: without plating). So, each group was consisted of 5 teeth and the gingival margin of each specimen was mesiodistally sectioned by 3 times and the marginal and internal gap were evaluated by the Stereo Microscope (${\times}180$) and the Scanning Electron Micrascope(${\times}5,000$) was used for examining the adhesive relationship of the resin cement to the cavity wall and to the cast gold surface. The results were as follows : 1. Marginal gap was less than internal gap in all groups. 2. ZPC and SNT(bevel without tin-plating) groups showed the least gap and gap in PNT(bevel without tin-plating) group, ST(bevel with tin-plating) group, PT(bevel with tin-plating) group showed the greater value in order in evaluation of the both internal gap and marginal gap. 3. With the exception of the relationships between ZPC and SNT groups, ST and PNT groups, relationships between any other groups showed the statistical significance in the internal gap(p<0.05). 4. In the marginal gap, all relationships between groups showed the statistical significance (p<0.05) except the relationships between ZPC and SNT groups, ST and PNT groups, ZPC and PNT groups. 5. ZPC group showed more soluble phenamena than the resin groups(ST, SNT, PT, PNT). 6. Resin cement showed the void spaces in spite of good penetration into the micro-irregularities on both the tooth surface and the cast surface. The void was shown more in PT and PNT groups than in the ST and SNT groups. 7. After the treatment of heat and desiccation for SEM specimen, resin cements were detached more easily from the tooth surface than from the cast surface.

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Generation Method of Expression Space for Realtime Facial Expression Control of 3D Avatar (3차원 아바타의 실시간 얼굴표정제어를 위한 표정공간의 생성방법)

  • Kim Sung-Ho
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.06a
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    • pp.109-111
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    • 2006
  • 본 논문은 애니메이터로 하여금 얼굴 표정들의 공간으로부터 일련의 표정을 선택하게 함으로써 3차원 아바타의 표정을 실시간적으로 제어할 수 있도록 하기 위한 표정공간의 생성방법에 관하여 기술한다. 본 시스템에서는 약 2400여개의 얼굴 표정 프레임을 이용하여 표정공간을 구성하였다. 본 기법에서는 한 표정을 표시하는 상태표현으로 얼굴특징 점들 간의 상호거리를 표시하는 거리행렬을 사용한다. 이 거리행렬의 집합을 표정공간으로 한다. 그러나 이 표정공간은 한 표정이 다른 표정까지 이동할 때 두 표정간의 직선경로를 통해 이동할 수 있는 그런 공간이 아니다. 본 기법에서는 한 표정에서 다른 표정까지 거쳐 갈 수 있는 경로를 캡쳐된 표정 데이터로부터 근사적으로 유추한다. 우선, 각 표정상태를 표현하는 거리행렬간의 거리가 일정 값 이하인 경우 두 표정을 인접해 있다고 간주한다. 임의의 두 표정 상태가 일련의 인접표정들의 집합으로 연결되어 있으면 두 표정간에 경로가 존재한다고 간주한다. 한 표정에서 다른 표정으로 변화할 때 두 표정간의 최단경로를 통해 이동한다고 가정한다. 두 표정간의 최단거리를 구하기 위해 다이내믹 프로그래밍 기법을 이용한다. 이 거리행렬의 집합인 표정공간은 다차원 공간이다. 3차원 아바타의 얼굴 표정 제어는 애니메이터들이 표정공간을 항해할 때 실시간적으로 수행된다. 이를 도와주기 위해 표정공간을 차원 스케일링 기법을 이용하여 2차원 공간으로 가시화하였고, 애니메이터들로 하여금 본 시스템을 사용하여 실시간 표정 제어를 수행하게 했는데, 본 논문은 그 결과를 평가한다.참여하는 빈들 간의 관계를 분석하여 워크플로우에 대한 성능 측정이 가능하도록 한다. 또한 제안된 메트릭을 통하여 EJB 어플리케이션의 성능 향상을 도모할 수 있도록 한다.로 표면 위로 자라났고, 부종은 창상 밑 조직까지 감소하였으며, 육아조직은 교원질 섬유로 대체되었다. 창상 유발 21일 후, 다른 창상에 비해, HG 처치창은 유의적으로 창상 표면이 거의 재생성 상피로 덮였으며, 육아조직은 창상 유발 14일 후와 비교해서 유의적으로 교원질 섬유로 대체되었다. 위의 모든 결과에서 보듯이, 개에서 전층피부 창상의 처치 시 HG의 사용은 HC와 생리 식염수에 비해 창상치유 복구기의 치유 속도를 촉진하는 것으로 사료된다.시범학교의 자녀를 들 부모들은 환경관련문제에 대한 의식 및 환경관련 제품에 대한 구매행동의 변화가 두드러지게 나타났다.EX>$d^{2+}$ + SA처리구는 두 화합물의 이중 효과에 의해 전반적인 생리 활성을 억제하여, 결국에는 식물의 고사를 유도하는 것으로 사료된다.목에 대한 보안'이 가장 중요한 것으로 나타났다. 본 연구에서는 솔루션 선정요인에 관한 중요도를 e-마켓플레이스의 유형과 산업 별로 평가해보았는데, 여기에서 밝혀진 중요도를 통해 e 마켓플레이스를 구축하고 자 하는 기업은 솔루션을 자체 개발하거나 구입할 때 올바른 의사결정을 할 수 있다. 그리고 솔루션을 제공하려는 기업측면에서는 e-마켓플레이스를 구축하고자 하는 기업에게 유형과 산업별로 적절한 솔루션을 제공할 수 있다.순환이 뇌대사 및 수술 후 신경학적 결과에 보다 유익한 효과를 제공해 줄 수 있음

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A Test on the Volatility Feedback Hypothesis in the Emerging Stock Market (신흥주식시장에서의 변동성반응가설 검정)

  • Kim, Byoung-Joon
    • The Korean Journal of Financial Management
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    • v.26 no.4
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    • pp.191-234
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    • 2009
  • This study examined on the volatility feedback hypothesis through the use of threshold GARCH-in-Mean (GJR-GARCH-M) model developed by Glosten, Jaganathan, and Runkle (1993) in the stock markets of 14 emerging countries during the period of January, 1996 to May, 2009. On this study, I found successful evidences which can support the volatility feedback hypothesis through the following three estimation procedures. First, I found relatively strong positive relationship between the expected market risk premiums and their conditional standard deviations from the GARCH-M model in the basis of daily return on each representative stock market index, which is appropriate to investors' risk-averse preferences. Second, I can also identify the significant asymmetric time-varying volatility originated from the investors' differentiated reactions toward the unexpected market shocks by applying the GJR-GARCH-M model and further find the lasting positive risk aversion coefficient estimators. Third, I derived the negative signs of the regression coefficient of unpredicted volatility on the stock market return by re-applying the GJR-GARCH-M model after I controlled the positive effect of predicted volatility through including the conditional standard deviations from the previous GARCH-M model estimation as an independent explanatory variable in the re-applied new GJR-GARCH-M model. With these consecutive results, the volatility feedback effect was successfully tested to be effective also in the various emerging stock markets, although the leverage hypothesis turned out to be insufficient to be applied to another source of explaining the negative relationship between the unexpected volatility and the ex-post stock market return in the emerging countries in general.

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The Variation of Germination, Growth and Leaf Form of Open-Pollinated Progenies of Cornus kousa Buerger ex Miquel in Korea (산딸나무(Cornus kousa) 풍매차대(風媒次代)의 발아(發芽), 생장(生長)및 엽형(葉型) 변이(變異))

  • Song, Jeong-Ho;Goo, Young-Bon;Han, Sim-Hee;Yang, Byeung-Hoon;Park, Hyung-Soon
    • Journal of Korean Society of Forest Science
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    • v.95 no.3
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    • pp.261-267
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    • 2006
  • A nursery trial comprising 109 progenies of 5 populations of Cornus kousa was analysed using multivariate analysis of 12 quantitative traits (growth and leaf form). The aim of this study was to examine geographic variation of the species based on the single, existing nursery trial to support a genetic resource conservation plan of Cornus kousa in Korea. Nested Anova showed that there were statistically significant differences among populations as well as among families within populations in all 12 quantitative traits. In 10 of 12 traits, variance components among families within populations were higher than those among populations. Cluster analysis using complete linkage method showed three groups to Euclidean distance 0.8. Among principal components, primary 2 principal components appeared to be major variables because of the loading contribution of 91.9%. The first contribution component was maximum width, vein number, blade length/petiole length and upper 1/3 width lower 1/3 width; the second one was height, diameter at root collar, blade length, upper 1/3 width, petiole length and petiole length/vein number, respectively. But all characters showed no significant difference with the pattern of geographic distribution.

Studies on the Host Selectivity and Pathogenicity of White Pine Blister Rust Fungus (Cronartium ribicola J. C. Fischer ex Rabenhorst) in Korea (우리나라 잣나무 털녹병균(病菌)의 기주선택성(寄主選擇性)과 병원성조사(病原性調査))

  • Yi, Chang Keun;Kim, Hyun Joong
    • Journal of Korean Society of Forest Science
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    • v.62 no.1
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    • pp.76-81
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    • 1983
  • Pedicularis spp. are the alternate hosts of the white pine blister rust fungi in the forests of Korea, and Ribes spp. were found as other alternate hosts by artificial inoculation test. New biotypes (races) with different host selectivity and pathogenicity of the causal fungi were speculated at various places in Korea. The aeciospores of the fungi were collected from two isolated places, Pyeongchang and Namwoen, and artificially inoculated on Pedicularis resupinata and six species of the genus Ribes. Among the tested alternate host species, P. resupinata and R. montigenum were only susceptible to both the Pyeongchang population and the Namwoen population, showing similar pathogencity between the two fungai populations. Three white pine species were planted in fungus-infested stands to study the susceptibility of each tree species. Four years later, 17.7% of Pinus koraiensis and 26.3% of the P. strobus were infected, but P. parviflora was free from attack. From the above results, it was concluded that the white pine blister rust fungus populations in Korea are of the same biotype, with P. koraiensis and P. strobus as aecial hosts, and Pedicularis spp. and Ribes spp. as telial hosts.

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Frequency and Wood Decaying Ability of Butt-rot Fungig Isolated form Larch (Larix leptolepis) (낙엽송근주심재부후병균(根株心材腐朽病菌)의 분포빈도(分布貧道)와 목재열화능력(木材劣化能力))

  • Kim, Hyun Joong;Cha, Ju Youngl;Yi, Chang Keun
    • Journal of Korean Society of Forest Science
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    • v.80 no.3
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    • pp.311-316
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    • 1991
  • Butt-rot fungi were isolated from decayed portion in butt rotted larch trees[Larix leptolepis(Sieb. et Zucc.) Gord.]. From a total of 216 affected trees in 38 forests of five provinces, Sparassis crispa(Wulf. ex Fr.) Fr. was isolated with the highest frequency, i.e.. 28% of the total trees. Laetiporus sulphureus(Fr.) Bond. et Sing, with 19%, and Phaeolus schweinitzii(Fr.) Pat. with 8%. However, none of these fungi was isolated from 45% of the trees. Wood decaying abilities and interaction of four basidiomycetous and three non-basidiomyo:etous fungi isolated from butt rotted trees were investigated. The weight loss of larch wood blocks, when exposed to the culture of a fungus for six months, was 19.6% for P. schweinitzii, 10% for S. crispa, 8.2% for L. sulphurous, 5.1% for Coriolus hirsutus, and less than 4.4% for three non-basidiomycetous fungi. In incubation with combinations of the fungi, the wood decay activity of S. crispa, L. sulphurous and C. hirsutus was increased by the non-basidiomycetous fungi of Geotrichum candidacy, G. sp. and Verticillium sp., but that of P. schweinitzii was not.

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The Effect of the Bujeonghangam-tang Extract on Hepatocellular Carcinogenesis and Hepatic Cirrhosis Induced by Diethylnitrosarnine and CCl4 in Rats (부정항암탕(扶正抗癌湯) 추출액이 Diethylnitrosamine과 CCl4로 유발된 흰쥐의 간암 형성 및 간경화에 미치는 영향)

  • Moon, Young-Ho;Won, Jin-Hee;Moon, Goo;Heo, Rae-Kyong;Seung, Kee-Moon;Lee, In-Young;Jang, Myung-Joon;Kwon, So-Yeon;Yu, Deok-Seon
    • Journal of Pharmacopuncture
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    • v.13 no.2
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    • pp.13-31
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    • 2010
  • Objective : Bujeonghangam-tang(BH) has been used for cure of tumor as a traditional medicine. This study was carried out to clarify the effect of BH extract on hepatocellular carcinogenesis and hepatic cirrhosis induced by Diethylnitrosamine(DENA) and $CCl_4$ in Rats. Method : Experimental groups were divided into two, 8th and 12th week groups, and subdivided into four; normal group(Nor), cirrhosis and hepatic cancer inducing control group(Con), and BH extract 320 mg/kg/day(BHA) or 640 mg/kg/day(BHB) administered groups to Con. Results: In the 8th week group: The body weight decreased significantly in Con compared with the Nor. The activities of transaminase, alkaline phosphatase(ALP), and lactacte dehydrogenase(LDH) were significantly increased(p<0.05) in the Con compared with Nor, but decreased in the BHA and BHB compared with Con. Alpha fetoprotein(AFP) were the most increased in the Con compared to BHA and BHB. The results of light microscopical observation, a number of hepatocytes were damaged in the Con compared with Nor and BH extract administerd groups. The number of hepatic p53 positive cells was reduced in the BH extract administered groups. According to the electron microscopical observation, hepatocarcinoma cells were observed distinctly in the Con compared with BH extract administered groups. In the 12 weeks group: The results of body were similar to 8th week groups. The activities of transaminase and ALT were significantly increased(p<0.05) in the Con compared with Nor. LDH was significantly(p<0.05) increased in the Con compared with Nor but significantly (p<0.05) decreased in the BHB. Alpha fetoprotein(AFP) were the most increased in the Con among ex perimental groups. The activities of superoxide dismutase(SOD) were significantly (p<0.05) increased in the Con, but the activities of catalase were not increased(p<0.05) compared with Nor. The number of hepatic p53 positive cells was increased in the Con. The results of electron microscopical observation were similar to 8th week groups. Conclusion : These results suggest that ad ministration of BH extract suppress or retard DENA and $CCl_4$-induced hepatocellular carcinogenesis and hepatic cirrhosis in rats.