• 제목/요약/키워드: ESI

검색결과 647건 처리시간 0.023초

온라인 자동화 시료 전처리 및 HR Orbitrap LC/ESI-MS를 이용한 환경시료 중 잔류 의약물질 분석방법 확립 (Establishment of the Analytical Method for Residual Pharmaceuticals in Raw Water Using Online Sample Preparation and High Resolution Orbitrap LC/ESI-MS)

  • 황윤정;신상희;박종숙
    • 한국물환경학회지
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    • 제29권3호
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    • pp.409-419
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    • 2013
  • In this study, the analytical method for 27 residual pharmaceuticals in raw water was developed. Online sample preconcentration/extraction and analysis with high resolution Orbitrap mass spectrometry (LC-ESI/Orbitrap MS) were performed. The calibration curves showed good linearities (above $r^2$ = 0.998) in the range of 5 ~ 1,000 ng/L. The method detection limit and the limit of quantification were 1.1 ~ 10.0 ng/L and 3.4 ~ 31.7 ng/L, respectively. Recoveries of the target compounds were between 70.1% and 115.8% (except cefadroxil, cefradine, vancomycin, and iopromide (50.2 ~ 67.0%)). The optimized analytical method can be useful to determine the residual pharmaceuticals in raw water.

Intracranial Chronic Subdural Hematoma Presenting with Intractable Headache after Cervical Epidural Steroid Injection

  • Kim, Myungsoo;Park, Ki-Su
    • Journal of Korean Neurosurgical Society
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    • 제58권2호
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    • pp.144-146
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    • 2015
  • Postdural punctural headache (PDPH) following spinal anesthesia is due to intracranial hypotension caused by cerebrospinal fluid (CSF) leakage, and it is occasionally accompanied by an intracranial hematoma. To the best of our knowledge, an intracranial chronic subdural hematoma (CSDH) presenting with an intractable headache after a cervical epidural steroid injection (ESI) has not been reported. A 39-year-old woman without any history of trauma underwent a cervical ESI for a herniated nucleus pulposus at the C5-6 level. One month later, she presented with a severe headache that was not relieved by analgesic medication, which changed in character from being positional to non-positional during the preceding month. Brain magnetic resonance imaging revealed a CSDH along the left convexity. Emergency burr-hole drainage was performed and the headache abated. This report indicates that an intracranial CSDH should be considered a possible complication after ESI. In addition, the event of an intractable and changing PDPH after ESI suggests further evaluation for diagnosis of an intracranial hematoma.

요통과 하지방사통에 대한 경막외 스테로이드 주입후 발생한 치명적 합병증 - 증례보고 - (Fatal Complications Following to Epidural Steroid Injections for Lumbago and Sciatica - Case Report -)

  • 김태준;김충현;정진환;백광흠;김재민;오석전
    • Journal of Korean Neurosurgical Society
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    • 제29권3호
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    • pp.420-425
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    • 2000
  • Epidural steroid injection(ESI) has been a commonly applied conservative therapy for the management of chronic low back pain and sciatica. However, there are many reports concerning various local, systemic and neurological complications related to ESI. We report two cases with fatal complications after ESI for low back pain and sciatica. In both patients, ventriculitis and meningitis were causative factors to be fatal. Aseptic procedures and careful post-procedure assessment are essential to avoid serious complications following ESI.

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Simultaneous determination of low molecular weight amines and quaternary ammonium ions by IC/ESI-MS

  • Jung, Joo-Young;Park, Han-Seok;Kim, Kang-Jin
    • 분석과학
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    • 제20권3호
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    • pp.255-260
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    • 2007
  • A new method for the simultaneous determination of low molecular weight amines and quaternary ammonium ions based on the separation by IC with a suppressor and the detection by MS with ESI has been developed. The method has been applied to the analysis of a mixture containing tetramethylammonium ion, tetraethylammonium ion, tetrapropylammonium ion, triethanolamine, trimethylamine and triethylamine. The constituents were separated by isocratic elution using an IonPac CS17 column, a cation-exchange column, and detected by conductivity and mass spectrometry. The newly developed method for the six components demonstrated that the repeatability in terms of relative standard deviation for three measurements was in the range of 0.1-0.5 %. The detection limits were between 0.2 and $0.9{\mu}g/mL$ by the IC/ESI-MS.

Comparison of clinical efficacy in epidural steroid injections through transforaminal or parasagittal approaches

  • Hong, Ji Hee;Park, Eun Kyul;Park, Ki Bum;Park, Ji Hoon;Jung, Sung Won
    • The Korean Journal of Pain
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    • 제30권3호
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    • pp.220-228
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    • 2017
  • Background: The transforaminal (TF) epidural steroid injection (ESI) is suggested as more effective than the interlaminar (IL) route due to higher delivery of medication at the anterior epidural space. However, serious complications such as spinal cord injury and permanent neural injury have been reported. The purpose of this study is to evaluate and compare the clinical effectiveness, technical ease, and safety of the TF and parasagittal IL (PIL) ESI. Methods: A total of 72 patients were randomized to either the PIL group (n = 41) or the TF group (n = 31) under fluoroscopic guidance. Patients were evaluated for effective pain relief by the numerical rating scale (NRS) and Oswestry Disability Index (ODI) (%) before and 2 weeks after the ESI. The presence of concordant paresthesia, anterior epidural spread, total procedure time, and exposed radiation dose were also evaluated. Results: Both the PIL and TF approach produced similar clinically significant improvements in pain and level of disability. Among the 72 patients, 27 PIL (66%) and 20 TF (64%) patients showed concordant paresthesia while 14 (34%) and 11 (36%) patients in the same respective order showed disconcordant or no paresthesia. Radiation dose and total procedure time required were compared; the PIL group showed a significantly lower radiation dose ($30.2{\pm}12$ vs. $80.8{\pm}26.8$ [$Cgy/cm^2$]) and shorter procedure time ($96.2{\pm}31$ vs. $141.6{\pm}30$ seconds). Conclusions: ESI under fluoroscopic guidance with PIL or TF approach were effective in reducing the NRS and ODI. PIL ESI was a technically easier and simple method compared to TF ESI.

해양 유출유 사고 방제 지원 GIS 프로그램 개발 (Building of GIS Program for Controlling Oil Spill Accident)

  • 김혜진;이한진;이문진
    • 한국지리정보학회지
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    • 제9권3호
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    • pp.58-66
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    • 2006
  • 환경 민감도 정보는 해양 유출유 사고시 효율적이고 신속한 방제 업무를 위한 유용한 정보이다. 유출유에 관련된 환경 민감도 정보의 종류가 다양하기 때문에 방제 현장에서 환경 민감도 정보에 대한 효율적인 접근과 활용 방안이 요구된다. 현장에서의 방제 업무 효율성을 높이기 위해서 환경 민감도 지도를 수치지도로 구축하고, GIS 기술을 이용한 전용 프로그램 개발이 필요하다. 본 연구에서는 경기만과 여수 지역을 대상으로 방제 업무 지원을 위한 환경 민감도 정보를 GIS 데이터베이스로 구축하고 GIS 프로그램을 개발하였다. 이를 위해 IMO/IPIECA의 환경 민감도 작성 지침과 해양경찰청의 방제 정보 지도 작성을 위한 정보 수집 지침에 따라 환경 민감도 정보를 수집하고, 환경 민감도 정보 표시 기호의 정의 및 업무 분석을 통한 방제 업무 지원 요소를 추출하였다. 향후 본 프로그램은 전 해역에 대한 환경 민감도 지도 전용 프로그램으로 활용될 수 있으며, 국가 차원의 해양 오염 방제 업무 지원 시스템 구축의 요소 기술로서의 가능성을 기대할 수 있다.

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위성영상기반 증발스트레스지수를 활용한 필지단위 논 가뭄 모니터링 (Drought Monitoring for Paddy Fields Using Satellite-derived Evaporative Stress Index)

  • 이희진;남원호;윤동현;김하영;우승범;김대의
    • 한국농공학회논문집
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    • 제63권3호
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    • pp.47-57
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    • 2021
  • Drought monitoring over paddy field area is an important role as the frequency and intensity of drought due to climate change increases. This study analyzed the applicability of drought monitoring on paddy crops using MODIS-based field surveys. As a satellite-based drought index using evapotranspiration for quantitative drought determination, ESI (Evaporative Stress Index), was applied and calculated through the ratio of MODIS- based actual and potential evapotranspiration. For the irrigated areas of Idong, Gosam, Geumgwang, and Madun reservoirs the availability of irrigation water supply, ponding depth, precipitation, paddy growth were investigated for the paddy field within one grid of MODIS. In addition, the percentile-based ESI drought severity was calculated to compare the growth process of paddy and changes in the drought category of ESI. The Idong area was irrigated about a week later than other reservoirs for the period of water supply, transplanting, and water drainage and the ESI drought category tended to be different. The Gosam, Geumgwang, and Madun area expressed moderate drought prior to the farming season, and indicated normal as the water was supplied. During the water drainage, the drought category intensified, indicating that the water available on land was decreasing. These results demonstrated that the MODIS-based ESI could be an effective tool for agricultural drought monitoring over paddy field area.

Quantitative assessment of steroid amount in the tissue after epidural steroid injection: a new rabbit model

  • Cho, Jungheum;Lee, Joon Woo;Lee, Eugene;Kang, Yusuhn;Cho, Ha Ra;Kim, Dong Yoon;Ho, Myoung Jin;Kang, Myung Joo;Choi, Yong Seok
    • The Korean Journal of Pain
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    • 제32권4호
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    • pp.264-270
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    • 2019
  • Background: To develop a rabbit epidural steroid injection (ESI) model for analyzing steroid retention in the tissue, and to assess the difference in steroid retention in the model according to the location and time elapsed after ESI. Methods: Fluoroscopy-guided ESI was performed using the interlaminar approach between the lowest two lumbar segments in 13 female New Zealand white rabbits. Four rabbits were allocated to each of three different groups according to the time of sacrifice: 3, 7, and 15 days post-ESI; the remaining rabbit was sacrificed immediately post-ESI to obtain baseline data. After sacrifice, two segments were harvested: the lowest two lumbar vertebrae and another two lumbar vertebrae immediately above these. The residual steroid amount (RSA) and residual steroid concentration (RSC) in the collected spinal columns were analyzed. A linear mixed model was used to compare RSAs and RSCs between the injected and adjacent segments, and among the number of days until sacrifice; P < 0.05 was considered statistically significant. Results: Both RSA and RSC of the injected segment were significantly higher than those of the adjacent segment (P < 0.001, both). The RSA and RSC significantly decreased over time (P = 0.009 and P = 0.016, respectively). Conclusions: The developed rabbit ESI model verified that significantly more steroid was retained at the injected segment than at the adjacent segment and the residual steroid decreased over time. This model could be useful not only for comparing current steroid medications, but also for developing new, better steroid formulations.

Evaporative Stress Index (ESI)를 활용한 국내 지역별 가뭄 특성 및 경향 분석 (Regional Drought Characteristics and Trends using the Evaporative Stress Index (ESI) in South Korea)

  • 윤동현;남원호;이희진;김대의
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2019년도 학술발표회
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    • pp.365-365
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    • 2019
  • 가뭄은 전 세계적으로 농업을 비롯한 사회, 경제적으로 큰 피해를 주는 자연 재해이며, 향후 피해 저감을 위해 가뭄의 경향을 파악하고 지역별 가뭄 특성을 파악할 필요가 있다. 위성영상을 활용한 가뭄 판단은 광역적 범위를 대상으로 다양한 밴드를 활용한 데이터를 주기적이고 일정한 수준으로 취득 가능하다는 장점이 있다. 농업 가뭄 분야의 위성영상 활용은 미계측 지역에 대한 정확한 데이터 취득이 어려운 지점데이터의 단점을 보완할 수 있다. 위성영상을 활용한 가뭄 지수로는 Leaf Area Index (LAI), Vegetation Health Index (VHI), Enhanced Vegetation Index (EVI) 등 다양한 지수들이 있으며, 본 연구에서는 단기 가뭄 판단에 활용되고 있는 Evaporative Stress Index (ESI)를 활용하였다. 국내 행정구역 기반의 가뭄 판단을 위해 Moderate Resolution Imaging Spectramadiometer (MODIS)위성의 MOD16A2 영상을 사용하였다. MOD16A2는 land surface temperature (LST)과 LAI의 계산을 통한 실제 증발산량과 FAO-56 Penman-Monteith 공식을 사용한 잠재증발산량을 포함한 다양한 데이터를 8일 주기의 500m 해상도로 제공하고 있다. 2001년부터 2018년까지 500m 해상도의 ESI를 산정하였으며, 국내의 과거 가뭄 경향 분석과 지역별 특성 파악을 위한 표준화를 수행하였다. 그 결과 과거 극심한 가뭄이 있었던 해 (2000-2001년, 2015-2017년 등)에 대한 농업 가뭄 경향 분석이 가능하였으며, 지역별 특성을 파악한 결과 상습가뭄 지역에서 가뭄 경향을 확인하였다. 농업 가뭄 분야에서 ESI의 활용은 가뭄 조기 경보 시스템 개발 및 위성영상 기반 가뭄 모니터링 기술 개발 등에 활용 가능할 것으로 기대된다.

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증발산 기반 ESI와 EDDI를 활용한 2022년 남부지역의 농업 가뭄 분석 (Comparative Analysis of the 2022 Southern Agricultural Drought Using Evapotranspiration-Based ESI and EDDI)

  • 박광수;남원호;이희진;서찬양;하태현;조영준
    • 한국농공학회논문집
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    • 제66권3호
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    • pp.25-37
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    • 2024
  • Global warming-induced drought inflicts significant socio-economic and environmental damage. In Korea, the persistent drought in the southern region since 2022 has severely affected water supplies, agriculture, forests, and ecosystems due to uneven precipitation distribution. To effectively prepare for and mitigate such impacts, it is imperative to develop proactive measures supported by early monitoring systems. In this study, we analyzed the spatiotemporal changes of multiple evapotranspiration-based drought indices, focusing on the flash drought event in the southern region in 2022. The indices included the Evaporative Demand Drought Index (EDDI), Standardized Precipitation Evapotranspiration Index (SPEI) considering precipitation and temperature, and the Evaporative Stress Index (ESI) based on satellite images. The Standardized Precipitation Index (SPI) and SPEI indices utilized temperature and precipitation data from meteorological observation stations, while the ESI index was based on satellite image data provided by the MODIS sensor on the Terra satellite. Additionally, we utilized the Evaporative Demand Drought Index (EDDI) provided by the North Oceanic and Atmospheric Administration (NOAA) as a supplementary index to ESI, enabling us to perform more effective drought monitoring. We compared the degree and extent of drought in the southern region through four drought indices, and analyzed the causes and effects of drought from various perspectives. Findings indicate that the ESI is more sensitive in detecting the timing and scope of drought, aligning closely with observed drought trends.