• Title/Summary/Keyword: ERT

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The Complete Chloroplast Genome Sequence and Intra-Species Diversity of Rhus chinensis

  • Kim, Inseo;Park, Jee Young;Lee, Yun Sun;Joh, Ho Jun;Kang, Shin Jae;Murukarthick, Jayakodi;Lee, Hyun Oh;Hur, Young-Jin;Kim, Yong;Kim, Kyung Hoon;Lee, Sang-Choon;Yang, Tae-Jin
    • Plant Breeding and Biotechnology
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    • v.5 no.3
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    • pp.243-251
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    • 2017
  • Rhus chinensis is a shrub widely distributed in Asia. It has been used for traditional medicine and ecological restoration. Here, we report the complete chloroplast genome sequence of two R. chinensis genotypes collected from China and Korea. The assembled chloroplast genome of Chinese R. chinensis is 149,094 bp long, consisting of a large single copy (97,246 bp), a small single copy (18,644 bp) and a pair of inverted repeats (16,602 bp). Gene annotation revealed 77 protein coding genes, 30 tRNA genes, and 4 rRNA genes. A phylogenomic analysis of the chloroplast genomes with 11 known complete chloroplast genomes clarified the relationship of R. chinensis with the other plant species in the Sapindales order. A comparative chloroplast genome analysis identified 170 SNPs and 85 InDels at intra-species level of R. chinensis between Chinese and Korean collections. Based on the sequence diversity between Korea and Chinese R. chinensis plants, we developed three DNA markers useful for genetic diversity and authentication system. The chloroplast genome information obtained in this study will contribute to enriching genetic resources and conservation of endemic Rhus species.

A Study on the Seeding Mixture Improvements for the Restoration and Revegetation of the Slopes by the Thin-Layer-Soil-Media Hydroseeding Revegetation Measures (생육보조재 취부 공법에 의한 비탈면 녹화 식생배합의 적정성에 관한 연구)

  • Kim, Jung-Hoon;Heo, Young-Jin;Kim, Nam-Choon;Cheong, Yong-Moon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.2
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    • pp.90-97
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    • 2005
  • This study aimed to address problems and suggest solutions in applying seed mixture design criterior of slope revegetation works according to the "Slope revegetation design and guidelines(proposed)" proposed by the Ministry of Construction and Transportation. To do this, a proper thickness of attaching soil media was identified in April experiment where the thickness and slopes varied. The results were as follows. In the test, the coverage rate of plot where exotic grass was not sowed increased with time and was 79.3% after three months of seeding, which indicated less risk of soil erosion. When applying the provisional standards of the plant mix proposed by the Ministry of Construction and Transportation, tree seeds and native plants were found ill in the early stage in all test lands due to exotic grass. This was because exotic grass which grew well in the early stage, could grow densely, so it might hamper the growth of other plants. When slope revegetation were planted and goals were set for herb, shrub and tree dominant mixture types, it was required to shift focus toward nursing up native plants first rather than early plantation of exotic grass.

A Study on the Seeding Mixture and Application Test for the Restoration and Revegetation of the Slopes by theThin-Layer-Soil-Media Hydroseeding Measures - Application by the S.O-Soil spray Measures - (얇은 식생기반재 취부공법에 의한 비탈면 녹화 식생배합 및 적용시험 연구 - S.O-Soil spray공법을 중심으로-)

  • Kim, Jung-Wan;Jung, Tea-Geun;Kim, Nam-Choon;Kwon, Byeong-Soung
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.9 no.6
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    • pp.143-151
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    • 2006
  • Currently, there are researches about environment-friendly road construction plans led by the Ministry of Construction and Transportation in progress. Therefore, in order to create the revegetation techniques of thin layer-soil combination media hydroseeding measures by actively using native herbs and native woody plants instead of using imported foreign grasses as a concept of sustainable environment-friendly land development, this thesis is going to identify problems that can appear when applying the thin- layer-soil-media hydroseeding measures by the suggested in the "Slope revegetation design and guidelines" proposed by the Ministry of Construction and Transportation, and to propose improvement plans for the problems.To this aim, a seeding mixture selection test was conducted by the goal of slope restoration, and a test group for artificial slope was created. As for a test for June sowing, it was intended to identify appropriate combination quantity by conducting a test that differentiates the combination quantity, and as for a test for September sowing, an artificial slope test was conducted by creating an artificial bank for earth and soil and applying 1~2cm and 3~4cm thickness after differentiating the seed combination volume and slope aspects.

A Study on the Use of Wood Waste for Slope Revegetation Techniques (임목폐기물 파쇄칩을 활용한 녹화기술의 비탈면 적용성에 관한 연구)

  • Koh, Jeung-Hyun;Hur, Young-Jin;Lee, Yong-Koo;Kim, Nam-Choon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.13 no.1
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    • pp.47-56
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    • 2010
  • The main objectives of this comparative study were 1) to quantify the potential contribution of wood chips to revegetation on the cut slope in a constructed area, 2) to compare the floristic similarity of species composition whether existing of wood chips in the soil media or not. Wood chips were combined with soil media in the ratio of 30%. The thin layer (1 cm, 3 cm) soil media revegetation methods and the thick layer (10 cm) soil media revegetation method were constructed on the cut slopes by machineries respectively. Also, comparative experiments the existence of wood chips in the soil media were conducted to evaluate the effects of wood chips on revegetation works. The total size of quadrat was $300m^2$ ($100m^2{\times}3$). The results of monitoring for 3 years on cut slopes were as follows: 1) All the quadrat existed in the proper range for vegetation. 2) Species richness of quadrat including wood chips was 10% more than those of commercial soil medias. 3) The coverage rates of quadrat including wood chips were similar or superior to those of conventional methods. It can be concluded that the use of wood chips would be effective to promote establishment of diverse landscape and vegetation. However, it behooves to continue monitoring on succession of vegetation for ecological restoration. Finally, adequate wood chips deposit and gathering methods should be studied properly.

Monitoring $CO_2$ injection with cross-hole electrical resistivity tomography (시추공간 전기비저항 토모그래피를 이용한 $CO_2$ 주입 모니터링)

  • Christensen, N.B.;Sherlock, D.;Dodds, K.
    • Geophysics and Geophysical Exploration
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    • v.9 no.1
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    • pp.44-49
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    • 2006
  • In this study, the resolution capabilities of electrical resistivity tomography (ERT) in the monitoring of $CO_2$ injection are investigated. The pole-pole and bipole-bipole electrode configuration types are used between two uncased boreholes straddling the $CO_2$ plume. Forward responses for an initial pre-injection model and three models for subsequent stages of $CO_2$ injection are calculated for the two different electrode configuration types, noise is added and the theoretical data are inverted with both L1- and L2-norm optimisation. The results show that $CO_2$ volumes over a certain threshold can be detected with confidence. The L1-norm proved superior to the L2-norm in most instances. Normalisation of the inverted models with the pre-injection inverse model gives good images of the regions of changing resistivity, and an integrated measure of the total change in resistivity proves to be a valid measure of the total injected volume.

Three-Dimensional Subsurface Resistivity Profile using Electrical Resistance Tomography for Designing Grounding Grid (접지 그리드 설계를 위한 전기 저항 단층촬영법에 기반한 지표의 3차원 저항률 분포 추정)

  • Khambampati, Anil Kumar;Kim, Kyung Youn
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.4
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    • pp.117-128
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    • 2016
  • Installation of earth grounding system is essential to ensure personnel safety and correct operation of electrical equipment. Earth parameters, especially, soil resistivity has to be determined in designing an efficient earth grounding system. The most common applied technique to measure soil resistance is Wenner four-point method. Implementation of this method is expensive, time consuming and cumbersome as large set of measurements with variable electrode spacing are required to obtain a one dimensional resistivity plot. It is advantageous to have a method which is of low cost and provides fast measurements. In this perspective, electrical resistance tomography (ERT) is applied to estimate subsurface resistivity profile. Electrical resistance tomograms characterize the soil resistivity distribution based on the measurements from electrodes placed in the region of interest. The nonlinear ill-posed inverse problem is solved using iterated Gauss-Newton method with Tikhonov regularization. Through extensive numerical simulations, it is found that ERT offers promising performance in estimating the three-dimensional soil resistivity distribution.

Substrate reduction therapy in three patients with Gaucher disease

  • Kim, Soo Hyun;Kang, Eungu;Kim, Yoon-Myung;Kim, Gu-Hwan;Choi, In-Hee;Choi, Jin-Ho;Yoo, Han-Wook;Lee, Beom Hee
    • Journal of Genetic Medicine
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    • v.13 no.2
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    • pp.72-77
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    • 2016
  • Purpose: Gaucher disease (GD) is the most common lysosomal storage disease caused by beta-glucocerebrosidase (GBA) deficiency. Oral substrate reduction therapy with miglustat ($Zavesca^{(R)}$) was approved for the treatment of adults with GD type 1, for whom enzyme replacement therapy (ERT) is unsuitable or not a therapeutic option. In this study, we report the effect of miglustat ($Zavesca^{(R)}$) in three Korean GD patients. Materials and Methods: Clinical findings comprising age at diagnosis, presenting signs, laboratory findings at diagnosis, GBA activity and mutations, and clinical courses of the three patients were reviewed. Results: Miglustat was administered to three patients who reported allergic reactions during intravenous imiglucerase infusions. One patient withdrew after 15 months of miglustat administration owing to continuous elevation of disease biomarker levels (chitotriosidase, acid phosphatase, and angiotensin-converting enzyme). Poor adherence to medication was suspected but was denied by the patient. In the other two patients, platelet count and levels of hemoglobin and other biomarkers remained stable during miglustat administration. However, they suffered from severe diarrhea and weight loss, which led to miglustat discontinuation after 1 and 12 months of administration. Conclusion: Our study shows that although miglustat is suggested to GD patients as an alternative treatment to ERT, significant adverse reactions may lead to discontinuation of miglustat. In addition, it is difficult to monitor the drug adherence.

Growth hormone treatment for children with mucopolysaccharidosis I or II

  • Minji Im;Chiwoo Kim;Juyoung Sung;Insung Kim;Ji-Hoon Hwang;Min-Sun Kim;Sung Yoon Cho
    • Journal of Genetic Medicine
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    • v.20 no.2
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    • pp.60-69
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    • 2023
  • Purpose: Despite enzyme replacement therapy (ERT) and/or allogeneic hematopoietic stem cell transplantation, individuals with mucopolysaccharidosis (MPS) I or II often experience significant growth deficiencies. This study aimed to assess the safety and efficacy of recombinant human growth hormone (hGH) treatment in children diagnosed with MPS I or II. Materials and Methods: A total of nine pediatric patients-four with MPS I and five with MPS II-underwent treatment with ERT and hGH at Samsung Medical Center. Results: The mean hGH dose administered was 0.26±0.03 mg/kg/week. In the MPS I group, three patients showed an increase in height Z-score from -4.09±0.83 to -3.68±0.43 after 1 year of hGH treatment, and to -3.10±0.72 by the end of the hGH regimen. In the MPS II group, while the height Z-score of four patients decreased according to standard growth charts, it improved from 1.61±1.79 to 2.71±1.68 based on the disease-specific growth chart through hGH treatment. Two patients discontinued hGH treatment due to lack of efficacy after 22 and 6 months each of treatment, respectively. No new-onset neurological symptoms or necessity for prosthetic or orthopedic surgery were reported during hGH treatment. Conclusion: This study provides insights into the impact of hGH on MPS patients, demonstrating its potential to reverse growth deceleration in some cases. Further research is needed to explore the long-term effects of hGH on changes in body composition, muscle strength, and bone health in this population.

Electrical Resistivity Tomography for Inverse Problem Using FEM (유한요소법을 이용한 전기 비저항 탐사법의 저항역산)

  • Lim, Sung-Ki;Kim, Min-Kyu;Jung, Hyun-Kyo;Koh, Chang-Seop
    • Proceedings of the KIEE Conference
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    • 1996.07a
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    • pp.154-156
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    • 1996
  • A new method for electric resistivity tomography(ERT) is developed for geophysical inverse problems by adapting the sensitivity analysis. The outputs of the potential electrodes are computed using two dimensional finite element method in the wave number space by Fourier transforming the governing equations. The resistance distribution in the region of interests, which makes the computed potential distribution coincide with the measured potential, is found by minimizing the objective function using an optimization method. In this process the sensitivity analysis is introduced in order to compute the derivatives of the objective function. And an adjoint variable method is used to save the computational efforts for sensitivity coefficients.

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Electrical Resistance Tomography: Mesh Grouping and Boundary Estimation Algorithms

  • Kim Sin;Cho Hyo-Sung;Lee Bong-Soo
    • International Journal of Contents
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    • v.1 no.1
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    • pp.1-5
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    • 2005
  • This paper presents the development and application of electrical resistance imaging techniques for the visualization of two-phase flow fields. Two algorithms, the so-called the mesh grouping and the boundary estimation, are described for potential applications of electrical resistance tomography (ERT) and results from extensive numerical simulations are also presented. In the electrical resistance imaging for two-phase flows, numerical meshes fairly belonging to each phase can be grouped to improve the reconstruction performance. In many cases, the detection of phase boundary is a key subject and a mathematical model to estimate phase boundary can be formulated in a different manner. Our results indicated that the mesh grouping algorithm is effective to enhance computational performance and image quality, and boundary estimation algorithm to determine the phase boundary directly.

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