• Title/Summary/Keyword: EN 1993

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The Crystal Structure of Fluoxymesterone, $C_{20}H_{29}FO_3$ (Fluoxymesterone, $C_{20}H_{29}FO_3$의 결정구조)

  • Kim, Ui-Seong;Park, Gwon-Il;Jo, Seong-Il
    • Korean Journal of Crystallography
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    • v.4 no.1
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    • pp.6-10
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    • 1993
  • 11 β ,17 β -dihydroxy-9a-fluoro-l7a-methyl androst-4-en-3-one (Fluoxymesterone), CgoH29 FO,, orthorhombic, P2,2,2,, a=13.468(5) A, b= 19.554 (2)A, c=6.578(9)A, a=b=r=90˚, A (CuKa)=1.5406 A , Dm=1.289cm-3, Dc=1.299cm-3 and Z=4 at T=298k. The structure was solved by direct method using seminvariants of ggg Parity group and refined by the full-matrix least-square method, resulting model with reliability factor R=0.069 for 1098 unique reflection over 3σ . Ring A is an 1β-2a-half chair, 5 ring has a highly symmetrical chair conformation, C ring is in a distorted chair conformation and D ring is a 13aenveLope conformation. In the crystal structure, the molecules are packed with a hydrogen bond of 011-H23‥‥03(0.5+x, 1.5-y, 1.0-z) [1.94(9) A of H‥‥0.2.786(9)A of 0‥‥0 and 165(8) ˚ of

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OZONE MEASUREMENTS IN THE STRATOSPHERE FROM KSR420S-1 AND -2 (과학 1, 2호 로켓 실험을 통한 성층권 오존량 측정)

  • Lee, K. Y.;Lee, D. H.;Kim, J.;Park, C. J.;Cho, H. K.
    • Journal of Astronomy and Space Sciences
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    • v.11 no.1
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    • pp.53-70
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    • 1994
  • The Korean sounding rockets(KSR420S-1, -2) equipped with ozone detectors have b3en launched at An-heung, Chungchungnam-do, on June 4 and September 1, 1993, respectively. The ozone detector is used to measure the attenuation of solar UV radiation for various frequency bands in the stratosphere, to obtain vertical profiles of the ozone number density in the stratosphere. They confirm that the maximum ozone densities occur near 25 km, which is quite consistent with the mean value in the mid-latitude region. Our results from KSR420S-1 and -2 are compared with the other observation data from the Dobson spectrophotometer at Yonsei Univ., the LIDAR at Kyunghee Univ., the SBUV from Nimbus satellite, and the TOVS from NOAA satellite, which were performed simultaneously with the sounding rocket experiments.

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Ultimate capacity of welded box section columns with slender plate elements

  • Shen, Hong-Xia
    • Steel and Composite Structures
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    • v.13 no.1
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    • pp.15-33
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    • 2012
  • For an axially loaded box-shaped member, the width-to-thickness ratio of the plate elements preferably should not be greater than 40 for Q235 steel grades in accordance with the Chinese code GB50017-2003. However, in practical engineering the plate width-to-thickness ratio is up to 120, much more than the limiting value. In this paper, a 3D nonlinear finite element model is developed that accounts for both geometrical imperfections and residual stresses and the ultimate capacity of welded built-up box columns, with larger width-to-thickness ratios of 60, 70, 80, and 100, is simulated. At the same time, the interaction buckling strength of these members is determined using the effective width method recommended in the Chinese code GB50018-2002, Eurocode 3 EN1993-1 and American standard ANSI/AISC 360-10 and the direct strength method developed in recent years. The studies show that the finite element model proposed can simulate the behavior of nonlinear buckling of axially loaded box-shaped members very well. The width-to-thickness ratio of the plate elements in welded box section columns can be enlarged up to 100 for Q235 steel grades. Good agreements are observed between the results obtained from the FEM and direct strength method. The modified direct strength method provides a better estimation of the column strength compared to the direct strength method over the full range of plate width-to-thickness ratio. The Chinese code and Eurocode 3 are overly conservative prediction of column capacity while the American standard provides a better prediction and is slightly conservative for b/t = 60. Therefore, it is suggested that the modified direct strength method should be adopted when revising the Chinese code.

A Study of Workers' Knowledge, Attitude, and Practice of the Occupational Health Services in Industries Located in Seoul (서울지역 산업장 근로자의 산업보건관리에 대한 지식, 태도, 실천 연구)

  • Jung, Yeun-Gang;Park, Shin-Ae;Lee, Na-Mi;Yoon, Soon-Young;Kim, Young-Im;Wang, Myoung-Ja;Lee, Soon-Nam;Kim, En-Hee;Ko, Young-Ae
    • Research in Community and Public Health Nursing
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    • v.4 no.2
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    • pp.91-99
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    • 1993
  • This research is undertaken for the purpose of providing basic data to improve the occupational health service for future. 415 workers of 46 firms in Seoul are included in this data points. Results from this analyzing are the following. 1) The level of knowledge, attitude and practice of workers on the occupational health is moderate. 2) The cognition of necessity about special health examination gains the highest point(3.94), but the understanding of the occupational health educational program gains the lowest point (.85) in the knowledge region. 3) In the attitude region, the highest point is marked by the workers' prudence of expending time on medical examination(3.45). The lowest one by the workers' feeling of satisfaction of the follow-up service after medical examination(1.79). 4) The workers' participation in medical examination is the most active(3.15), and that in occupational health education in the least active(.86) in the practical region.

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A Survey of Current Status on the Science Education of the Special Classroom(School) managed by Firm (산업체(産業體) 부설(附設) 특별학급(特別學級) (학교(學校))의 과학교육(科學敎育) 실태(實態) 조사(調査))

  • Chung, Won-Woo;Yoh, Sao-Dong;Park, Jong-Hwan;Kim, En-Kyung
    • Journal of The Korean Association For Science Education
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    • v.13 no.2
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    • pp.282-295
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    • 1993
  • This study was accomplished to survey of current situation and management of science education in the special classroom(school) managed by firm. The status of management and the evalution of the scientific inquiry ability were taken on workers attending 17 Special Classes and 9 Special Schools located in Taegu City and Kyungpuk Province. As a responses, most students chose the subject "Science"as an option within their limited 8 units credits. About 88.5% of the students were female. About 78.3% of the classes/schools were conducted in the evening only. About 59.4% of teaching staffs were prevailed with female in these classes, and most of them were young, naive, and unexperienced with their major in chemistry and physics. Insufficient facilities and equipments, crowded classes, understaffed instructors, and inappropriated text materials. etc., were reasons for the students not receiving maximum benefit from these classes and schools. In order to evaluate of scientific inquiry ability, 25 items were constructed and administered to 250 students. The processes of scientific inquiry were classified into 5 categories(category I : establishing a subjects, category II : planning a experiments, category III : conducting a experiments. category IV : interpreting a result of experiments, category V : formulating generalization). As the result obtained from the achivement test analysis, the scores for all the students were significantly low, and the scores for girls were higher than those for boys. The results of test in the selected students showed that inquiry abilities in the category I, II and V were higher than those in category III and IV.

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Radiation Induced $G_2$ Chromatid Break and Repair Kinetics in Human Lymphoblastoid Cells (인체 임파양세포에서 $G_2$기 염색체의 방사선 감수성)

  • Seong, Jin-Sil
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.193-203
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    • 1993
  • In understanding radiosensitivity a new concept of inherent radiosensitivity based on individuality and heterogeneity within a population has recently been explored. There has been some discussion of possible mechanism underlying differences in radiosensitivity between cells. Ataxia telangiectasia (AT), a rare autosomal recessive genetic disorder, is characterized by hypersensitivity to ionizing radiation and other DNA damaging agents at the cellular level. There have been a lot of efforts to describe the cause of this hypersensitivity to radiation. At the cellular level, chromosome repair kinetics study would be an appropriate approach. The purpose of this study was to better understand radiosensitivity En an approach to investigate kinetics of induction and repair of $G_2$ chromatic bleaks using normal, AT heterozygous (ATH), and AT homozygous lymphoblastoid cell lines. In an attempt to estimate initial damage, $9-{\beta}-D-arabinosyl-2-fluoroadenine,$ an inhibitor of DNA synthesis and repair, was used in this study. It was found from this study that radiation induces higher chromatid breaks in AT than in normal and ATH cells. There was no significant differences of initial chromatid breaks between normal and ATH cells. Repair kinetics was the same for all. So the higher level of breaks in AT $G_2$ cells is thought to be a reflection of the increased initial damage. The amount of initial damage correlated well with survival fraction at 2 Gy of cell survival curve following radiation. Therefore, the difference of radiosensitivity in terms of $G_2$ chromosomal sensitivity is thought to result from the difference of initial damage.

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A study en the preference and food behavior of the children in primary school foodservice II (아동의 기호도와 식습관에 관한 조사연구 ( II ))

  • Lee, Won-Myo;Bang, Hyeong-Ae
    • Journal of the Korean Dietetic Association
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    • v.2 no.1
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    • pp.69-80
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    • 1996
  • This study was performed to investigate the food preference trends of the children according to age increase and change of the times. The subjects were 1,450 children who are fifth grade of primary school and 2,000 juveniles who are senior high school in 1993. This survey data were compared with the Food preference study of the primary school aged children in 1987.' The results of this study can be summarized as follows 1. State of the general taste The subject had a high preferences to bulgogi(roast beef), panbroiled cuttlefish, steamed egg, fried sausage and donuts among the all sorts of 165 principal and subsidiary foods. But, fried beef liver, pancake, sweet potato with syrup, spinach soup and boiled rice with red bean didn't suit for their taste. Compared with survey data done in 1987, in present study significantly increased preferences to steamed food, pan frying and parboiled vegetables were shown. Particularly, food preference was changed with the cooking methods rather than materials. 2. Differences of the preference according to change of the times In present study, except the rice cakes preferences to all sorts of foods were improved and markedly increased preferences to steamed food, parboiled vegetables and mixed with seasonings were observed. Compared with 87's study deviation of the preference to cooking materials was decreased considerably. Preferences to salty tasted foods as like as stew and salted food were low no better than before. 3. Changes of preference according to age increase Among the principal foods, increased preferences to boiled rice and cereals were shown but to one-dish meal, bread and rice cake were decreased. Among the subsidiary foods, significantly decreased preference to frying was observed. Irrespectively of the cooking methods, preferences to fish and vegetables were improved. And in the frying and panbroiled foods, deviation of preferences to cooking materials were considerable, which means the fixation of food behavior.

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Purification of Thiazole- and Pyrazine-inducible Microsomal Epoxide Hydrolase: Induction of Epoxide Hydrolase-related Novel 43 kDa Protein (Thiazole 또는 Pyrazine유도성 Microsomal Epoxide Hydrolase의 순수정제: Epoxide Hydrolase-관련성 43 kDa 단백질의 유도증가)

  • Kim, Sang-Geon
    • The Korean Journal of Pharmacology
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    • v.29 no.2
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    • pp.275-282
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    • 1993
  • Liver microsomal epoxide hydrolase (mEH) is active in the detoxification of epoxide-containing reactive intermediate. Previous studies in this laboratory have shown that thiazole and pyrazine are efficacious inducers of mEH in rats with large increases in mEH mRNA levels (Carcinogensis, Kim et al, 1993). mEH was purified to electrophoretic homogeneity from thiazole-induced rat hepatic microsomes using DEAE-cellulose column chromatography whereas another protein $({\sim}43\;kDa)$ was co-purified with mEH from pyrazine-induced rat hepatic micrsomes (200 mg/kg body weight/day, ip, 3d). The antibody raised from a rabbit against mEH protein purified from thiazole-induced rat hepatic microsomes appeared to specifically recognize mEH protein in rat hepatic microsomes, as assessed by immunoblotting analysis. Immunoblotting analyses revealed a 10- and 7-fold increase in mEH levels in the hepatic microsomes isolated from thiazole- and pyrazine-treated rats, respectively. Moreover, immunoblotting analysis showed cross-reactivity of the mEH antibody with a 43 kDa protein in pyrazine-induced rat hepatic microsomes and with co-purified 43 kDa protein in purified fractions. The ratio between the 43 kDa protein and mEH in pyrazine-induced rat microsomes or in purified fractions was ${\sim}1$ to 15. N-terminal amino acid sequence analysis of both purified rat mEH and 43 kDa protein revealed that 10 out of 12 amino acids in N-terminus of the 43 kDa protein were identical with the mEH sequence with two amino acid residues of the 43 kDa protein undetermined. Either thiazole or pyrazine treatment, however, failed to increase the levels of mEH protein in rabbits while pyrazine caused elevation of the 43 kDa protein in this species, as determined by irnrnunoblotting analysis. These results demonstrated that treatment of rats with either thiazole or pyrazine causes elevation in hepatic mEH expiession whereas pyrazine treatment results in induction of another mEH-related 43 kDa protein and that a distinct species difference exists between rats and rabbits in the induction of mEH by these xenobiotics.

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Some Considerations on the Establisment of the Exclusive Economic Zone in Korea (한국의 배타적 경제수역 설정에 관한 연구)

  • 이윤철
    • Journal of the Korean Institute of Navigation
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    • v.17 no.4
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    • pp.1-21
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    • 1993
  • The purpose of this paper is to search for reasonable and fair principles applicable to the delimitation of the Exclusive Economic Zone(which is called the EEZ, hereinafter) around the Korean Peninsula th-rought the comprehensive study of maritime boundary, which is one of the most important issues in the law of the Sea. So far, the sea has been exploited for activities such as fishery, transport and military stratedy, and en-vironmental policy and so on. From this time on, however, it becomes important to us as the major trea-sure-house of various resources which will be developed and used for diversified purposes. For these rea-sons, nowadays, more and more countries of the world are competing to secure waters as much as possible within their jurisdiction. And the regime of the EEZ was created as a result of this international trend. At last, it has been institutionalized as the 200-mile EEZ of a legal notion in the Convention on the Law of the Sea, which was adopted at the Third United Nations Conference on the Law of the Sea, in Jamaica on December 10, 1982. In adapting to this EEZ institution, Korea is faced with several complicated problems as it is bounded on three sides by the sea and all of its neighboring countries such as the PRC, the DPRK, Japan, Russia etc are less than 400 miles away between opposite countries. Therefore, when trying to delimit the boun-dary for the EEZ, it appears necessary to analyze applicable principles and rules of international law for delimitation mainly through the Convention on the Law of the Sea, and studies the trends of actual State practices and recent international precedents. It is hoped that such knowledge will enable Korea to secure sufficient resources and other sovereign rights without conflicting with the neighboring countries concer-ned. For the achievement of the above mentioned object. I analyzed the necessities of the establishment of the EEZ in Korea, the difficulties and practices of Korea's neighbors, and the changes and forthcoming trends in Korea's relations with its neighbors concerned on the basis of the general explanation of the EEZ regime. In conclusion, it is my opinion that for the establishment of the EEZ delimitation which neighbors around the Korean Peninsula should be applied reasonable and equitable principles considering the rele-vant circumstances which characterize the area definitely as well as the UN Convention on the Law of the Sea, 1982.

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A Study on the Health Care Management of Industries in Seoul (서울지역 산업장의 보건관리)

  • Jung, Yeun-Gang;Park, Shin-Ae;Lee, Na-Mi;Yoon, Soon-Young;Kim, Young-Im;Wang, Myoung-Ja;Lee, Soon-Nam;Kim, En-Hee;Ko, Young-Ae
    • Research in Community and Public Health Nursing
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    • v.4 no.1
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    • pp.5-13
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    • 1993
  • The objective of this study was to analyze the status of health examination, and the health care management of industries in Seoul. This will provide effective industrial health care services. 46 industries were selected as a sample, and were given self administered questionnaire developed by the academic affairs of community health nursing. The results of this study are as follows: (1) The general characteristics of industries: The greater part of the industries were manu facturing companies, 300-900 workers, in a one shift system. (2) The general characteristics of health man ager: 96% of the companies had industrial nurses and the larger industries had comprehensive health managers. 90% of the industrial nurses were full-time employees and 77% of the industrial physician were part time employees. 80% of the industrial physician were age 50 or older, while 59% of the industrial nurses were 25-29 years of age. (3) Health examination and follow up care: The proportions of the workers who took general health examination was 94%. Of those, 12% took secondary examinations. In secondary examinations, 36% were evaluated at the C-grade, 20% were evaluated at the D-grade. The proportion of the workers who were required to take special examination were 29% and of that, the proportion of the workers who actually took the examination was 88%. 85% of the workers who were recommended for follow up cares were given follow up care while working. The physical agents among the special examination were done the most frequently to detect the examination effects. (4) Health care services: Industrial nurses performed health examination most frequently and health education was done the least. There were significant differences in health care services according to the size of the industries. Companies with 300 workers or less had higher health care services than other groups. The three primary reasons of health care management and examinations of workers are: First, industrial nurses are requires to accumulate professional knowledge and experience through continuos' activities. Second, systematic and concert examination for industrial workers should be performed periodically. Third, it needs developing health education strategies that are important workers for health promotion in industries.

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