• Journal of Microbiology and Biotechnology
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• v.17 no.3
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• pp.398-402
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• 2007

Abstract Female mice post weaning were exposed to 20 kHz sawtooth electric and magnetic fields (EMF) with $6.25{\mu}T$ peak intensity for 6 weeks. Estrous cycles were checked using vaginal smears over the last 10 days of the experimental period. The vaginal smears from EMF-exposed mice revealed an increase in the frequency of one or two phases persisting. The number of estrous cycles less than 1 was more in the EMF-exposed group than in the sham control group. Furthermore, in the EMF-exposed group, the duration of proestrous and metestrous stages of the estrous cycle was significantly increased compared with the control group. In conclusion, our results suggest that exposure to 20 kHz sawtooth EMF may affect normal cycling of the estrous cycle by disrupting the female reproductive endocrine physiology. We should not disregard the possible adverse reproductive effect of the 20 kHz sawtooth EMF generated under the occupational exposure situation in females.

• The Journal of the Korea institute of electronic communication sciences
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• v.14 no.3
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• pp.613-618
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• 2019

EMF (Electromagnetic Field) is a valuable resource for living in a knowledge-based information society. The EMF is used in home appliances that make our lives easy and convenient, and in telecommunication devices such as mobile phones, personal computers, medical devices and broadcasting towers. However, the biological hazards associated with EMF exposure are also increasing in signal from telecommunication devices. Studies of the effects of EMF exposure on humans have been conducted for a long time, but it has not yet been demonstrated whether the EMF effect is harmful. In this paper, we examine the electromagnetic field emitted from various electronic devices around living and its effect.

• Journal of electromagnetic engineering and science
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• v.15 no.3
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• pp.151-157
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• 2015

The increasing use of mobile phones has raised public concern about the possible biological effects of radiofrequency electromagnetic field (RF-EMF) exposure on the human brain. To investigate the potential effect of RF-EMF exposure on the brain, we examined the behaviors and hippocampal morphology of C57BL/6 mice after sub-chronic exposure to RF-EMFs with a relatively high SAR level (5.0 W/kg). We applied a 2-hour daily exposure of WCDMA 1,950 MHz using a reverberation chamber that was designed for whole-body exposure for 60 days. In the behavioral tests, RF-EMF did not alter the physical activity or long-term memory of mice. Moreover, no alteration was found in the neuronal and glial cells in the hippocampus by RF-EMFs. In this study, we showed that sub-chronic whole body RF exposure did not produce memory impairment and hippocampal morphological alteration in C57BL/6 mice.

• Clinical and Experimental Pediatrics
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• v.63 no.11
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• pp.422-428
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• 2020

In today's world, most children are exposed to various manmade electromagnetic fields (EMFs). EMFs are electromagnetic waves less than 300 GHz. A developing child's brain is vulnerable to electromagnetic radiation; thus, their caregivers' concerns about the health effects of EMFs are increasing. EMF exposure is divided into 2 categories: extremely low frequencies (ELFs; 3-3,000 Hz), involving high-voltage transmission lines and in-house wiring; and radiofrequencies (RFs; 30 kHz to 300 GHz), involving mobile phones, smart devices, base stations, WiFi, and 5G technologies. The biological effects of EMFs on humans include stimulation, thermal, and nonthermal, the latter of which is the least known. Among the various health issues related to EMFs, the most important issue is human carcinogenicity. According to the International Agency for Research on Cancer's (IARC's) evaluation of carcinogenic risks to humans, ELFs and RFs were evaluated as possible human carcinogens (Group 2B). However, the World Health Organization's (WHO's) view of EMFs remains undetermined. This article reviews the current knowledge of EMF exposure on humans, specifically children. EMF exposure sources, biological effects, current WHO and IARC opinions on carcinogenicity, and effects of EMF exposures on children will be discussed. As well-controlled EMF experiments in children are nearly impossible, scientific knowledge should be interpreted objectively. Precautionary approaches are recommended for children until the potential health effects of EMF are confirmed.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.3
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• pp.277-289
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• 2018

The exponential increase in the use of mobile communication has triggered public concerns about the potential adverse effects of radiofrequency electromagnetic fields (RF-EMF) emitted by mobile phones on the central nervous system (CNS). In this study, we explored the relationship between calcium channels and apoptosis or autophagy in the hippocampus of C57BL/6 mice after RF-EMF exposure with a specific absorption rate (SAR) of 4.0 W/kg for 4 weeks. Firstly, the expression level of voltage-gated calcium channels (VGCCs), a key regulator of the entry of calcium ions into the cell, was confirmed by immunoblots. We investigated and confirmed that pan-calcium channel expression in hippocampal neurons were significantly decreased after exposure to RF-EMF. With the observed accumulation of autolysosomes in hippocampal neurons via TEM, the expressions of autophagy-related genes and proteins (e.g., LC3B-II) had significantly increased. However, down-regulation of the apoptotic pathway may contribute to the decrease in calcium channel expression, and thus lower levels of calcium in hippocampal neurons. These results suggested that exposure of RF-EMF could alter intracellular calcium homeostasis by decreasing calcium channel expression in the hippocampus; presumably by activating the autophagy pathway, while inhibiting apoptotic regulation as an adaptation process for 835 MHz RF-EMF exposure.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.12
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• pp.942-952
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• 2018

A wireless power transfer (WPT) system for an urban railroad is currently under development in S. Korea. This system supplies power to railroad cars using 60 kHz magnetic fields. The electromagnetic fields (EMFs) generated by the WPT system should satisfy established safety requirements for exposure of the human body to these fields. However, EMF measurements and the safety assessment methods for fields generated by the WPT system have not yet been established. As such, a measurement and safety assessment method for EMF generated by a WPT system for an urban railroad is proposed in this report. The EMF generated by this WPT system on a test railroad was measured and compared to the reference level set by the human safety standard for EMF exposure.

• Journal of Ginseng Research
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• v.35 no.2
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• pp.138-148
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• 2011

Exponential rise in the use of mobile communication devices has generated health concerns due to radiofrequency (RF) exposure due to its close proximity to the head. Calcium binding proteins like calretinin regulate the levels of calcium ($Ca^{2+}$) which plays an important role in biological systems. Ginseng is known for maintaining equilibrium in the human body and may play a beneficial radioprotectant role against electromagnetic field (EMF) exposure. In the present study, we evaluated the radioprotective effects of red ginseng (RG) extract in a mouse model. Calretinin (CR) expression was measured using a free-floating immunohistochemical method in the hippocampus of mice after 835 MHz EMF exposure for 5 h/d for 5 d at specific absorption rate=1.6 W/kg for the different experimental groups. The control animals were treated with NaCl while the experimental animals received 10 mg/kg ginseng, or 30 mg/kg; EMF exposed mice were also treated with NaCl, 10 mg/kg ginseng (E10), or 30 mg/kg (E30). Decreases in CR immunoreactivity (IR) along with loss of CA1 and CA3 interneurons and infragranular cells were observed in the ENaCl group while such losses were not observed in the E10 and E30 groups. CR IR significantly increased in the RG-treated group compared to control and EMF-exposed groups treated with NaCl. The study demonstrates that RG extract can serve as a radioprotective agent that maintains $Ca^{2+}$ homeostasis and prevents neuronal loss in the brain hippocampal region caused by RF exposure.

• The Korean Journal of Physiology and Pharmacology
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• v.14 no.6
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• pp.427-433
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• 2010

This study was conducted to investigate the effects of extremely low frequency electromagnetic fields (EMF) on signal pathway in plasma membrane of cultured cells (RAW 264.7 cells and RBL 2H3 cells), by measuring the activity of phospholipase $A_2$ ($PLA_2$), phospholipase C (PLC) and phospholipase D (PLD). The cells were exposed to the EMF (60 Hz, 0.1 or 1 mT) for 4 or 16 h. The basal and $0.5\;{\mu}M$ melittin-induced arachidonic acid release was not affected by EMF in both cells. In cell-free $PLA_2$ assay, we failed to observe tbe change of $cPLA_2$ and $sPLA_2$ activity. Also both PLC and PLD activities did not show any change in the two cell lines exposed to EMF. This study suggests that the exposure condition of EMF (60 Hz, 0.1 or 1 mT) which is 2.4 fold higher than the limit of occupational exposure does not induce phospholipases-associated signal pathway in RAW 264.7 cells and RBL 2H3 cells.

• Journal of Electrical Engineering and Technology
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• v.7 no.3
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• pp.376-383
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• 2012

A number of scientific researches are currently being conducted on the potential health hazards of power frequency electric and magnetic field (EMF). There exists a non-objective and psychological belief that they are harmful, although no scientific and objective proof of such exists. This possible health risk from ELF magnetic field (MF) exposure, especially for children under 17 years of age, is currently one of Korea's most highly contested social issues. Therefore, to assess the magnetic field exposure levels of those children in their general living environments, the personal MF exposure levels of 436 subjects were measured for about 6 years using government funding. Using the measured database, estimation formulas were developed to predict personal MF exposure levels. These formulas can serve as valuable tools in estimating 24-hour personal MF exposure levels without directly measuring the exposure. Three types of estimation formulas were developed by applying evolutionary computation methods such as genetic algorithm (GA) and genetic programming (GP). After tuning the database, the final three formulas with the smallest estimation error were selected, where the target estimation error was approximately 0.03 ${\mu}T$. The seven parameters of each of these three formulas are gender (G), age (A), house type (H), house size (HS), distance between the subject's residence and a power line (RD), power line voltage class (KV), and the usage conditions of electric appliances (RULE).

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.23 no.1
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• pp.132-140
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• 2009

For human exposure assessment of UHF RFID system, electric field distribution of commercial 900[MHz] RFID antenna was measured and analyzed. Also, SAR(Specific Absorption Rate) of RFID antenna was calculated by simulation, and compared with basic restrictions in EMF guidelines. For EMF exposure assessment according to EN and IEC standards, the reader was tested for the normal operation, and electric field from RFID antenna was measured at various distances and angles. For electric field measurement, narrow band isotropic electric field probe was used, and the measurements were made at 0.3, 0.5, 1.0 and 1.5[m] for every 15[$^{\circ}$] angle from the antenna. Also, the rationale for measurement distance in EN and IEC standards is analyzed from the measurement results.