• 제목/요약/키워드: EH grade

검색결과 11건 처리시간 0.018초

Low Microsomal Epoxide Hydrolase Expression is Associated with Bladder Carcinogenesis and Recurrence

  • Zhang, Zhe;Yu, Xiu-Yue;Zhang, Guo-Jun;Guo, Kun-Feng;Kong, Chui-Ze
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권2호
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    • pp.521-525
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    • 2012
  • Microsomal epoxide hydrolase (mEH) plays a significant role in the metabolism of numerous xenobiotics and is associated with several forms of cancer. Here, we investigated the role of mEH expression in bladder carcinogenesis, subsequent progression and recurrence. The expression of mEH was analyzed by Western blot in 50 bladder urothelial carcinoma and 20 normal epithelial tissues. There was a significantly higher mEH expression in the normal epithelium (P<0.05) and mEH expression was lower in high stage than in low stage tumors (P<0.05). Further, immunohistochmistry in 106 bladder urothelial carcinoma demonstrated mEH expression to be negatively correlated with histological grade, pT stage and recurrence (P<0.05). These findings suggest the important role of mEH in bladder carcinogenesis, cancer development and recurrence, providing support for efforts to develop mEH-based gene therapy.

1mm 응력 기법을 적용한 EH 강재 필릿 용접 이음부 피로 강도 평가 (A Study of Assessment for Fatigue Strength of EH Steels at Fillet Welded Joints using 1mm Stress Method)

  • 신문걸;오동진;김영남;김명현
    • 대한조선학회논문집
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    • 제51권1호
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    • pp.26-33
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    • 2014
  • In this study, Non-load-carrying EH Grade steels in fillet welded joints were evaluated with both the hot spot stress method and the 1mm stress method. The thickness effect criterion for fatigue strength evaluation of welded of welded steel structures recommendations of the IIW was used to evaluate the fatigue strength of EH40 and EH36 and Both EH40 and EH36 have been compared with FAT 125 curve recommended in the IIW. Furthermore, fatigue strength of the welded tow and the ground conditions for Non-load-carrying EH36 based on the 1mm stress method has been discussed.

메탈코어드 콤포지트 와이어를 사용한 SAW 용접금속 성분변화 (Chemical composition of SAW weld metal welded with metal cored composite wire)

  • 정동희;방국수;정홍철;이종봉;박철규
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 2007년 추계학술발표대회 개요집
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    • pp.310-312
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    • 2007
  • Two metal cored composite wires were manufactured to satisfy AWS F7A4-EC-G specification. They were used to weld EH36 grade steels with three different fluxes. Variation of carbon, manganese, silicon, titanium, and boron contents which affect the weld metal strength in weld metal was investigated.

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선급 극후물재의 취성균열 전파 정지 인성에 미치는 용접변수의 영향 (Effect of welding variables on the crack arrest toughness of thick steel plate)

  • 류강묵;안규백;김태수;이태영;이종섭
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 2009년 추계학술발표대회
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    • pp.103-103
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    • 2009
  • As the size of containership increased over 14,000TEU, thick steel plate with high strength has been used. The plate thickness increased over 70mm and yield strength of the steel plate was around $47kg_f/mm^2$. Many researchers reported that the thick welded plate has low crack arrest toughness. They noticed the crack arrest ability is dependent on the plate thickness. In other words, brittle crack propagates straightly along the welded line and make abrupt fracture in the thick plate which causes low $K_{ca}$. In this study, the other factors, especially welding heat input, to cause low crack arrest toughness was investigated for thick steel plate welds. EH grade steel plates were used in this study and 50 to 80 thick plates were tested to confirm thickness sensitivity. Electro gas welding (EGW) and flux cored arc welding (FCAW) were adopted to prepare the welded joints. Temperature gradient ESSO test was performed to measure $K_{ca}$ values with the variation of welding variables. As a result of this study, regardless of plate thickness, welding heat input to cause welding residual stress around crack path is a key factor to control the brittle crack propagation in welded joints.

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TMCP 고장력강 용접부의 피로 특성에 관한 연구 (Fatigue properties of welded joints for TMCP steels)

  • 임채범;권영각;엄기원
    • Journal of Welding and Joining
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    • 제8권2호
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    • pp.40-52
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    • 1990
  • Fatigue behavior of the AH, DH and EH grade TMCP(Thermo-Mechanical Control Process) steels was studied. High cycle and low cycle fatigue tests were carried out for the weldment and base metal of each steel. The results showed that the fatigue limit at 2 * $10^6$ cycles was 33 to 37 kg/$mm^2$ for the base metal and 30 to 34 kg/$mm^2$ for the weldment. The ratio of fatigue limit to tensile strength for TMCP steels was 0.65 to 0.71, which was a value close to the upper limit for the ordinary steels. It was also found that the high cycle fatigue behavior of TMCP steels could be affected by the microstructures of base metal. It will be necessary to have fine structure for TMCP steels to increase the fatigue resistance. In low cycle fatigue test, the fatigue lifetime of AH and DH steels accorded well with the ASME best fit curve, while that of EH steel was considerably lower than the fatigue lifetime of the other steels. Fatigue resistance of the weldment made by high heat input(180kJ/cm) welding was not lower than that made by low heat input(80kJ/cm) welding in case of high cycle fatigue, but the high heat input welding decreased the fatigue resistance in case of low cycle fatigue.

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연관 마이닝과 고객 선호도 기반의 인터넷 상품 검색 시스템 설계 및 구현 (Design and Implementation of Product Searching System on Internet using the Association Mining and Customer's Preference)

  • 황현숙;어윤양
    • Asia pacific journal of information systems
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    • 제12권1호
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    • pp.1-16
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    • 2002
  • Most of searching systems used by shopping-mall provide too much information for user requirements or fail to provide appropriate items reflecting customer's preference. This paper aims to design and implement the product searching systems based on customer preference which will enable efficient product selection in the internet shopping-mall. The proposed system consists of user/provider interface, searching and model agent, data management system, and model management system. Especially, we construct the searching pattern database to support fast search using association mining method. And this system includes the customer-oriented decision model which shows the highly preferred products. Input weight value per attribute and preference level should be needed to compute priority grade of preference.

구조 응력 기법을 적용한 필릿 용접부 두께 지수 산정에 관한 연구 (A Study of the Thickness Effect using Structural Stress Approach for Fillet Welded Joints)

  • 신문걸;오동진;김명현
    • Journal of Welding and Joining
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    • 제32권2호
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    • pp.37-42
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    • 2014
  • In this study, non-load-carrying fillet welded joints fabricated using EH grade-steel are evaluated with the structural stress approach. The thickness effect was investigated by a study on welded steel joints with thickness ranging from 25 to 80mm. As-welded joint for main plate thickness of 25 to 80mm, the fatigue strength is reduced gradually. On the other hand, in case of main plate thickness of 25 to 80mm, the structural stress concentration factor increases gradually. As a result, for structural stress approach, thickness effect is not required for correction. Based on these results, a new evaluation fillet welded joint for fatigue design purposes has been proposed FAT 125.

임프란트의 상부구조물 형상과 하중조건에 따른 3차원 유한요소해석을 이용한 하악골의 응력분포에 관한 연구 (THREE-DIMENSIONAL STRESS ANALYSIS OF IMPLANT SYSTEMS IN THE MANDIBULAR BONE WITH VARIOUS ABUTMENT TYPES AND LOADING CONDITIONS)

  • 신하식;전흥재;한종현;이수홍
    • 대한치과보철학회지
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    • 제41권5호
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    • pp.617-625
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    • 2003
  • Statement of problem : There are many studies focused on the effect of shape of futures on stress distribution in the mandibular bone. However, there are no studies focused on the effect of the abutment types on stress distribution in mandibular bone. Purpose : The purpose of this study is to investigate the effect of three different abutment types on the stress distributions in the mandibular bone due to various loads by performing finite element analysis. Material and method : Three different implant systems produced by Warantec (Seoul, Korea), were modeled to study the effect of abutment types on the stress distribution in the mandibular bone. The three implant systems are classified into oneplant (Oneplant, OP-TH-S11.5). internal implant (Inplant, IO-S11.5) and external implant (Hexplant, EH-S11.5). All abutments were made of titanium grade ELI. and all fixtures were made of titanium grade IV. The mandibular bone used in this study is constituted of compact and spongeous bone assumed to be homogeneous, isotropic and linearly elastic. A comparative study of stress distributions in the mandibular bone with three different types of abutment was conducted. Results : It was found that the types of abutments have significant influence on the stress distribution in the mandibular bone. It was due to difference in the load transfer mechanism and the size of contact area between abutment and fixture. Also the maximum effective stress in the mandibular bone was increased with the increase of inclination angle of load. Conclusion : It was concluded that the maximum effective stress in the bone by the internal implant was the lowest among the maximum effective stresses by other two types.

FGB SAW 용접부 물성에 미치는 Ni과 Mo의 영향에 관한 연구 (Effect of Ni and Mo on Mechanical Properties of Submerged Arc Welds with Flexible Glasswool Backing)

  • 지춘호;최준태;김대주
    • 대한용접접합학회:학술대회논문집
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    • 대한용접접합학회 2009년 추계학술발표대회
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    • pp.55-55
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    • 2009
  • FGB(Flexible Glasswool Backing) Submerged Arc Welding has been one of the main welding processes for one side butt welding in shipbuilding industries, which can efficiently improve the welding productivity by the addition of a supplementary filler metal into the molten weld pool. As recent ships have become larger in size, the application of high tensile and higher grade of steels has been continuously increased. Single pass FGB SA welding process accompanies such a high heat input when welding thick plates that the mechanical properties of weld metal can be dramatically degraded. This study has been performed in order to obtain high toughness and tensile properties of high heat input FGB SA welds, and to evaluate the effect of alloy elements on their mechanical properties. To complete welding 25mm-thick EH36 grade steel plate by single pass, 1.2mm diameter and 1.0mm long cut wires has been distributed in the groove before welding, and three different test coupons have been made using C-1.5%Mn, C-1.8%Mn-0.5%Mo, and C-1.4%Mn-1.7%Ni cut wires to investigate the influence of nickel(Ni) and molybdenum(Mo) on the mechanical properties of welds. Test results showed that the addition of Ni and Mo effectively promotes the formation of Acicular Ferrite(AF), while significantly reducing the amount of Grain Boundary Ferrite(GBF) in weld metal microstructures, which resulted in a beneficial effect on low temperature impact toughness and strength.

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카자흐스탄 제스카즈간 동광상의 성인 고찰 (Discussion on Genesis of the Zhezkazgan Copper Deposit in Kazhkstan)

  • 문건주
    • 자원환경지질
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    • 제30권4호
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    • pp.379-393
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    • 1997
  • Geology of the Zbezkazgan copper deposit in Kazhkstan is mainly composed of Permian and Carboniferous sedimenary rocks in which copper minerals are mainly contained in grey sandstone of Carboniferous age. There are 28 layers of copper ore bodies in Zbezkazgan suite. Thickness of the ore bodies ranges from one to 35 meters, grade of the crude ore ranges from 2 to 5 wt % Cu and the extension of the orebodies is 5 to 7 km. Microscopic study on specimens from the Zbezkazgan ore deposit has exposed clues to understand the origin of this deposit. Alternatively deposited grey sandstone and red sandstone are mainly composed of quartz and feldspar grains. A big difference between the grey sandstone and the red sandstone is in grain size, the former is larger than the latter. Chalcocites as main copper minerals have cemented through grain boundary. It is assumed that quartz, feldspar and copper were derived from granitoid in which copper mineralization had taken place before exposing to weathering. The chalcocites were precipitated by a sudden change of geochemical condition (Eh, pH, temperature, etc.) of fluid which had carried quartz, feldspars, copper ions and sulphate during formation of grey sandstones. The copper ions and sulphate were stable in fluid during sedimentation of oxidation environment, however, the copper ions were no more stable at the reduced environment and changed to stable forms to precipitate copper minerals by reaction of copper ions and hydrogen sulfides. This chemical precipitation of copper minerals in the sandstone attributes to the assumption of hydrothermal origin on this sedimentary origined deposit.

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