• 비파괴검사학회지
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• 제17권4호
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• pp.262-269
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• 1997

발전 설비중 열교환기 튜브와 같이 단면 형상이 원형인 부품의 원주 방향으로 마모, 침식 등에 의해 발생할 수 있는 단면 형상 변화를 검사(profilometry)하기 위한 와전류 탐촉자를 임피던스 등가회로이론을 적용하여 개발하였다. 본 연구에서는 외경 9.68mm, 벽두께 0.47mm인 SS304 튜브 외부에 발생할 수 있는 마모, denting 등의 결함을 모의한 시편을 제작하여 실험을 통해 검출 감도와 S/N비가 최적인 탐촉자의 코일치수, 전기적 특성, 적용 시험 주파수 등을 설정하였다. 이 결과에 따라 단면 형상 검사용 $8{\times}1$ 다중표면 탐촉자를 설계 제작하여 모의시편의 각 결함별 마모율을 검사한 결과 튜브 외부 발생 단면 형상 변화를 튜브외경의 ${\pm}0.2%$ (0.022mm) 측정 오차 범위로 측정이 가능함을 확인하였다.

• 대한디지털의료영상학회논문지
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• 제9권2호
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• pp.11-16
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• 2007

We have evaluated and compared of gradient echo and spin echo EPI for compensating about deeply distortion aspect in case of post-operation patients in magnetic resonance image. A total of 100 patients were performed on 3.0 T(GE Signa Excite E2, USA) with 8ch head coil. As a result of analysis, The SNRs of whiter and gray matter areas were 36.74 $\pm$ 06 and 39.96 $\pm$ 09 in the gradient echo EPI, the SNRs which white and gray matter areas were slightly higher than gradient echo EPI(P<0.005, paired student t-test). It was 46.24 $\pm$ 11 and 51.38 $\pm$ 13 in gradient and spin echo EPI, respectively. The signal intensity in the whiter and gray matter areas also were 87.33 $\pm$ 15.24 and 140.66 $\pm$ 13.45 in the gradient echo EPI techniques, The signal intensity of gradient echo EPI showed higher values compared to spin echo EPI. Otherwise, gradient echo EPI technique is distortion enough to operation wound and edge of the image, while spin echo EPI technique did not appear almost. In this point, the spin echo EPI technique, after surgical operation according to patient state beside gradient echo EPI techniques that signalbeside gradient echo EPI techniques that signal intensity is high and patient's case which image distortion is serious by metal etc, will be provide the useful information in adults and pediatric patients.

• 폴리머
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• 제24권6호
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• pp.802-809
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• 2000

Poly(L-glutamic acid) (PLGA)와 PVA 블렌드막을 제조한 후, ethanol 수용액중에서 막증의 polypeptide 사슬의 2차구조 전이거동에 미치는 용매조성 및 대이온종의 영향과 알칼리 금속 이온 (Li, na, K, Cs)에 대한 투과특성을 조사하였다. 막중 PLG 알칼리 금속염의 helix 형성거동에 있어 대이온 선택성은 Li>Na>K>Cs의 순으로 관찰되었고, 이와 같은 특이성은 탈용매화 에너지와 정전에너지의 감소에 따른 고분자 하전기와 대이온과의 contact ion-pair 형성에 의한 것으로 설명하였다. 또한 PLGA/PVA 블렌드막의 ethanol 수용액 중에서의 알칼리 금속이온의 투과거동을 살펴보면, ethanol 농도가 점차 증가함에 따라 K, Cs의 경우는 투고도가 증가한, Li, Na의 경우에는 감소하였다. K, Cs 이온의 경우 대이온과 염소이온간의 ion-pair (M$^{+}{\cdot}$Cl$^{-}$)형성에 의한 Donnan배제효과의 감소와 중성염 형태로의 분배량 증가때문인 것으로, Li, Na 이온의 경우 막중의 coil-helix 구조전이에 따른 자유체적의 감소와 고분자 하전기와의 상호작용이 증가하여 확산성이 크게 감소하였기 때문인 것으로 생각된다.

• 한국미생물·생명공학회지
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• 제9권3호
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• pp.165-171
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• 1981

E. coil ATCC 9637의 균체를 젤라틴과 DEAE-cellulose의 혼합 성형 후 글루트알데히드 가교법으로 제조론 고정화 penicillin amidase의 differential column reactor에서의 반응속도를 논의하였다. 이러한 반응조의 최적 조작조건은 효소충진량 1g, 기질농도30mM(0.1M 인산완충액, pH8.0), 유출속도 4 $m\ell$/min, 온도 4$0^{\circ}C$이었다. 이 최적조건에서 고정화효소의 일반적인 성질을 조사하였다. Km 상수는 4.8mM 이었고 specific activity 308 units/g 고정화 효소이 었다. 또한 고정화효소에서는 기질에 의한 효소반응 저해효과가 보이지 않았다. 이러한 differential column reactor에서는 column내에서의 pH 감소효과 및 외부 화산효과가 없어지기 때문에 이러한 외부적 영향을 받지 않는 고정화효소의 반응 속도론적 연구에 적합함을 알았다.

• Journal of Astronomy and Space Sciences
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• 제35권3호
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• pp.185-193
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• 2018

Jang Bogo Station (JBS), the second Korean Antarctic research station, was established in Terra Nova Bay, Antarctica ($74.62^{\circ}S$ $164.22^{\circ}E$) in February 2014 in order to expand the Korea Polar Research Institute (KOPRI) research capabilities. One of the main research areas at JBS is space environmental research. The goal of the research is to better understand the general characteristics of the polar region ionosphere and thermosphere and their responses to solar wind and the magnetosphere. Ground-based observations at JBS for upper atmospheric wind and temperature measurements using the Fabry-Perot Interferometer (FPI) began in March 2014. Ionospheric radar (VIPIR) measurements have been collected since 2015 to monitor the state of the polar ionosphere for electron density height profiles, horizontal density gradients, and ion drifts. To investigate the magnetosphere and geomagnetic field variations, a search-coil magnetometer and vector magnetometer were installed in 2017 and 2018, respectively. Since JBS is positioned in an ideal location for auroral observations, we installed an auroral all-sky imager with a color sensor in January 2018 to study substorms as well as auroras. In addition to these observations, we are also operating a proton auroral imager, airglow imager, global positioning system total electron content (GPS TEC)/scintillation monitor, and neutron monitor in collaboration with other institutes. In this article, we briefly introduce the observational activities performed at JBS and the preliminary results of these observations.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.513-514
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• 2006

Recently intradiscal electrothermal therapy is introduced, which is a new and minimally invasive technique fer the treatment of discogenic low back pain. This procedure involves the percutaneous threading of a flexible catheter into the disc under fluoroscopic guidance. The catheter, composed of thermal resistive coil, heats the posterior annulus of the disc, causing contraction of collagen fibers and destruction of afferent nociceptors. This study tries to investigate the effects of the important factors of this procedure such as heat source temperature and heat applying time on the temperature distribution within the intervertebral disc. This study utilized both computer simulation and the experiment for the verification of finite element analysis. FE analysis was carried out with ANSYS v7.0 (ANSYS Inc, USA) using 10,980 number of brick element and 12,551 number of node. The functional spinal units of 5 month old swine were used for the experiment and the temperature was monitored using 10 channel temperature measurement device MV200. Through this study, it was able to analyze the temperature range of inner intervertebral disc by two mechanisms which are known to alleviate pain clinically. The results showed that when the heat source temperature was kept up 80 degree for 1,020 seconds, the temperature of inner annulus reached at 45 degree up to the distance of 15.6mm from heat source, which explains coagulation of inner annulus by heat. When the same heat source was used, the temperature of inner nucleus reached at 60 degree up to the distance of 9mm from heat source, which explains contraction of inner nucleus by heat.

• 센서학회지
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• 제6권6호
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• pp.466-475
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• 1997

본 논문에서는 초소형 코일-마그넷으로 구성되는 전자 트랜스듀서를 이용하는 청각보조용 이식형 인공중이를 설계하였다. 세라믹 방식의 진동체에 비하여 음향특성은 우수하나 효율이 낮은 것이 문제점으로 지적되고 있는 전자 트랜스듀서 방식의 진동체를 효과적으로 구현하기 위하여 객관화된 진동체의 설계방안을 제시하였으며 시스템의 전력 전달 효율을 향상시킬 수 있도록 FM방식의 음성신호 전달용 체외기와 체내기를 설계하였다. 설계된 트랜스듀서 및 체외기와 체내기의 실험세트를 만들어 금속스트립 및 사체의 측두골을 대상으로 진동특성을 측정하였다. 그 결과 FM방식의 신호전달기법이 갖는 장점을 확인할 수 있었으며 증폭된 입력 음압에 해당하는 진동을 효과적으로 이소골에 전달할 수 있음을 보였다.

• 한국초전도ㆍ저온공학회논문지
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• 제14권3호
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• pp.9-12
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• 2012

Usually, the AC loss from the superconducting element of an SFCL due to the load current is very small because it is composed of the combination of bifilar windings with very small reactance. Although the AC loss is small enough, we should be albe to predict for the design and control of the cryogenic system. In fact, an SFCL for the transmission voltage class may not generate ignorable AC loss because of the inevitable space between the HTS wires for the high voltage insulation and cryogenic efficiency. To measure the AC loss dependency on the space between the 2G HTS wires with the width of 4.4 mm, we prepared an experimental setup which could adjust the distance between the wires. We used two 500-mm length HTS wires in parallel and applied the current in the opposite direction for each wire to simulate a part of a current limiting module for a high voltage SFCL. We also put two couples of voltage taps at the ends of each wire and a cancel coil in the voltage measurement circuit to compensate the reactive component from the voltage taps. In this condition, we varied the distance between the wires to investigate the change of the transport current loss. A similar experimental study with HTS wire with the width of 12 mm is now in progress.

• 대한치과교정학회지
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• 제21권3호
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• pp.635-656
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• 1991

It was the aim of this investigation to evaluate some histologic aspect of rat pulp tissue after it had been compromised by an experimental orthodontic force. Experimental animals of thirty five Spraque-Dawley rats were employed. The first upper molars had been successively mesial moved (initial load 100 gr.) with a closed coil spring during 21 days. The experimental periods were set on immediate, 1 day, 1 week, 2 weeks, 3 weeks, 4 weeks following retention time. On each experimental period, the rats were killed and prepared for the light microscopy. After prepared with H/E stain and Gomori's one-step trichrome stain, the specimens were analyzed with evaluation criteria which were adopted in this study. The result may be summarized as follows; 1. The main pulp changes due to experimental orthodontic force included vacuolization of odontoblastic layer, circulation disturbance, root resorption, reduced pulp collagenous fiber density and mean cell count of pulp fibroblast in the immediate group. 2. The pulp tissue changes were revealed reversible because the relieved pulp tissues from experimental orthodontic force were recovered rapidly in each evaluation criteria during retention periods. 3. Compared with normal control group, pulp collagenous fiber density were decreased in immediated group (p < 0.01), but increased in each retention groups. These seem to suggest that the pulp tissues were aged after experimental orthodontic force conditions. 4. Compared with normal control group, mean cell counts of pulp fibroblasts were decreased in immediate group (p < 0.05), but increased continuous in each retention groups. These seem to indicate that the pulp tissues were highly regenerative after experimental orthodontic force conditions. 5. Compared with normal control group, root resorptions occurred in all immediate specimens (p < 0.01) and they were healed in each retention periods, but often observed in 4 weeks retention group. These seem to indicate that root resorptions were recovered slowly after experimental orthodontic force conditions.

• Molecules and Cells
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• 제39권6호
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• pp.495-500
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• 2016

We have solved the crystal structure of a predicted fructose-specific enzyme $IIB^{fruc}$ from Escherichia coli ($EcEIIB^{fruc}$) involved in the phosphoenolpyruvate-carbohydrate phosphotransferase system transferring carbohydrates across the cytoplasmic membrane. $EcEIIB^{fruc}$ belongs to a sequence family with more than 5,000 sequence homologues with 25-99% amino-acid sequence identity. It reveals a conventional Rossmann-like ${\alpha}-{\beta}-{\alpha}$ sandwich fold with a unique ${\beta}$-sheet topology. Its C-terminus is longer than its closest relatives and forms an additional ${\beta}$-strand whereas the shorter C-terminus is random coil in the relatives. Interestingly, its core structure is similar to that of enzyme $IIB^{cellobiose}$ from E. coli ($EcIIB^{cel}$) transferring a phosphate moiety. In the active site of the closest $EcEIIB^{fruc}$ homologues, a unique motif CXXGXAHT comprising a P-loop like architecture including a histidine residue is found. The conserved cysteine on this loop may be deprotonated to act as a nucleophile similar to that of $EcIIB^{cel}$. The conserved histidine residue is presumed to bind the negatively charged phosphate. Therefore, we propose that the catalytic mechanism of $EcEIIB^{fruc}$ is similar to that of $EcIIB^{cel}$ transferring phosphoryl moiety to a specific carbohydrate.