• Title/Summary/Keyword: E-box

Search Result 494, Processing Time 0.028 seconds

Variation Calcium Carbonate Content in Deep-Sea Pelagic Sediments of the Western Pacific Ocean (서태평양 심해 원양성 퇴적물의 탄산염 함량 변화)

  • Khim, Boo-Keun;Kim, Yeo-Hun;Kim, Hyung-Jeek;Hyeong, Ki-Seong;Yoo, Chan-Min
    • Ocean and Polar Research
    • /
    • v.32 no.1
    • /
    • pp.15-22
    • /
    • 2010
  • Calcium carbonate ($CaCO_3$) content was measured from 3 box core (BC060301, BC060303, BC070301) sediments, in addition to pilot core (PC313) sediments, from deep waters within the Western Pacific Ocean. At the two collection sites (BC060301, PC313) located close to the equator, downcore variation exhibited low $CaCO_3$ content during the interglacial period and high $CaCO_3$ content during the glacial period. Variation of coarse fraction (>$63\;{\mu}m$) content also followed changes in $CaCO_3$ content, indicating that dissolution effect of bottom water decreased during the glacial period. Such variation pattern is typical of the Pacific Ocean. However, downcore variation at the two collection sites (BC060303, BC070301) in the Philippine Sea contrasted the trend of the previous two cores (i.e., high $CaCO_3$ content during the interglacial period and low during the glacial period). This pattern is typical of the Atlantic Ocean. Such results may be attributed to the increasing dilution effect, initiated possibly by the increased transportation of terrigenous materials from nearby continent and archipelago during the glacial period when sea level was low. Alternatively, it is possible that the non-carbonate biogenic particles may have been responsible for dilution. Because of these uncertainties, the record of $CaCO_3$ variation in the deep Western Pacific Ocean is not regionally consistent.

Multiple Linkage Disequilibrium Mapping Methods to Validate Additive Quantitative Trait Loci in Korean Native Cattle (Hanwoo)

  • Li, Yi;Kim, Jong-Joo
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.28 no.7
    • /
    • pp.926-935
    • /
    • 2015
  • The efficiency of genome-wide association analysis (GWAS) depends on power of detection for quantitative trait loci (QTL) and precision for QTL mapping. In this study, three different strategies for GWAS were applied to detect QTL for carcass quality traits in the Korean cattle, Hanwoo; a linkage disequilibrium single locus regression method (LDRM), a combined linkage and linkage disequilibrium analysis (LDLA) and a $BayesC{\pi}$ approach. The phenotypes of 486 steers were collected for weaning weight (WWT), yearling weight (YWT), carcass weight (CWT), backfat thickness (BFT), longissimus dorsi muscle area, and marbling score (Marb). Also the genotype data for the steers and their sires were scored with the Illumina bovine 50K single nucleotide polymorphism (SNP) chips. For the two former GWAS methods, threshold values were set at false discovery rate <0.01 on a chromosome-wide level, while a cut-off threshold value was set in the latter model, such that the top five windows, each of which comprised 10 adjacent SNPs, were chosen with significant variation for the phenotype. Four major additive QTL from these three methods had high concordance found in 64.1 to 64.9Mb for Bos taurus autosome (BTA) 7 for WWT, 24.3 to 25.4Mb for BTA14 for CWT, 0.5 to 1.5Mb for BTA6 for BFT and 26.3 to 33.4Mb for BTA29 for BFT. Several candidate genes (i.e. glutamate receptor, ionotropic, ampa 1 [GRIA1], family with sequence similarity 110, member B [FAM110B], and thymocyte selection-associated high mobility group box [TOX]) may be identified close to these QTL. Our result suggests that the use of different linkage disequilibrium mapping approaches can provide more reliable chromosome regions to further pinpoint DNA makers or causative genes in these regions.

The Effect of Intrathecal Epigallocatechin Gallate on the Development of Antinociceptive Tolerance to Morphine (척수강 내로 투여한 Epigallocatechin Gallate이 모르핀의 항침해 작용에 대한 내성 발생에 미치는 효과)

  • Kim, Woong Mo;Bae, Hong Beom;Choi, Jeong Il
    • The Korean Journal of Pain
    • /
    • v.22 no.3
    • /
    • pp.199-205
    • /
    • 2009
  • Background: A major ingredient of green tea is epigallocatechin-3-gallate (EGCG), and this is known to have many beneficial effects for cancer prevention and also on the cardiovascular system and neurodegenerative diseases through its anti-oxidant, anti-angiogenic, anti-inflammatory, lipid-lowering and neuroprotective properties. Its actions on nociception and the spinal nervous system have been examined in only a few studies, and in these studies EGCG showed an antinociceptive effect on inflammatory and neuropathic pain, and a neuroprotective effect in motor neuron disease. This study was performed to investigate the effect of EGCG on acute thermal pain and the development of morphine tolerance at the spinal level. Methods: The experimental subjects were male Sprague-Dawley rats and the Hot-Box test was employed. A single or double-lumen intrathecal catheter was implanted at the lumbar enlargement for drug administration. An osmotic pump was used to infuse morphine for 7 days for induction of morphine tolerance. EGCG was injected repeatedly for 7 days at twice a day through the intrathecal catheter. Results: Intrathecal EGCG increased the paw withdrawal latency (PWL) after repeated administration for 7 days at twice a day, but this did not happen with administering on single bolus injection of EGCG. In addition, the antinociceptive effect of intrathecal morphine was not affected by co-administration with EGCG. A continuous 7-day infusion of morphine caused a significant decrease of the PWL in the control group (M + S, morphine plus saline). In contrast, intrathecal EGCG injection over 7 days blocked the decrease of the PWL in the experiment group (M + E, morphine plus EGCG). Conclusions: Intrathecal ECGC produced a weak antinociceptive effect for acute thermal pain, but it did not change the morphine's analgesic effect. However, the development of antinociceptive tolerance to morphine was attenuated by administering intrathecal EGCG.

A New Investigation Methodology of Marine Casualties and Incidents using Digital Forensic Techniques (디지털 포렌식 기법을 이용한 해양사고 조사 방법론)

  • Baek, Myeong-Hun;Lee, Sangjin
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.23 no.3
    • /
    • pp.515-530
    • /
    • 2013
  • The results of investigations into marine incidents have become an important basis in determining not only possible causes, but also the extent of negligence between the perpetrator and victim. However, marine incidents occur under special circumstances i.e. the marine environment, and this leads to difficulties in identifying causes due to problems in scene preservation, reenactment and acquisition of witnesses. Given the aforementioned characteristic of marine incidents, the International Convention for the Safety of Life at Sea (SOLAS) has adopted mandatory regulations on the carriage of Voyage Data Recorders (VDRs) and Automatic Identification Systems (AIS) for ships of a certain gross tonnage and upwards, so as to reflect recent developments in radio communication and marine technology. Adopted to provide an international standard for investigations and to promote cooperation, the Code of the International Standards and Recommended Practices for a Safety Investigation into a Marine Casualty or Marine Incident (Casualty Investigation Code) recommends member states to build capacity for analysis of VDR data. Against this backdrop, this paper presents methods for efficient investigations into the causes behind marine incidents based on data analysis of VDR, which serves as the black box of ships, as well as digital forensic techniques.

Logical view based Copy-Ahead technique for P2P IPTV (P2P IPTV 성능향상을 위한 논리 뷰 기반 Copy-Ahead기법)

  • Song, Young-Ho;Kwon, Taeck-Geun
    • Journal of Korea Multimedia Society
    • /
    • v.13 no.7
    • /
    • pp.933-942
    • /
    • 2010
  • The convergence of the telecommunication industry through the combination of existing network technology and multimedia technology has brought along interactive data services in addition to the traditional broadcast services by providing direct connections between the users and the broadcasters. The interactive data service technology has developed a network which is able to fully support QoS and also a fast enough channel changing technology that is satisfactory to the user, are prerequisites for IPTV success, to provide satisfactory levels of service to exist users. However the current server-client system can't support all increasing needs of users. To overcome these limitations, P2P based IPTV service is currently under researched. Therefore, this thesis proposes a logical view based copy-ahead technique for P2P IPTV to improve the performance of IPTV system.

A Study on Bending Fatigue Strength of One Side Fillet Welded T-Joint by SM 490A steel (Sm 490A강으로 제작된 T형 편면용접이음재의 굽힘피로강동에 관한 연구)

  • 엄동석;강성원;이태훈;이해우;조수형
    • Journal of Welding and Joining
    • /
    • v.16 no.5
    • /
    • pp.134-141
    • /
    • 1998
  • In this study, a fillet size for bending fatigue strength of one side fillet welded T-joint, used in box type girder and other welding structure, was investigated by bending fatigue test with or without edge preparation and burn through, with variation of joint shape. As a result, the following conclusions were obtained. (1) In one side fillet welded T-joint, the larger the leg length, the greater the bending fatigue strength. The increase in bending fatigue strength. (2) One side filet welded T-joint with edge preparation showed higher bending fatigue strength than that with twofold-large leg length and without edge preparation. (3) In one side fillet welded T-joint without edge preparation, both manual welding and automatic welding were carried out with same condition. In this case, automatic welding shoed deeper penetration and more increased horizontal leg length than manual welding, so that automatic welding offers grater bending fatigue strength. (4) For one side fillet welded T-joint without edge preparation, the ratio(h/t) of the leg length (h) and the main plate thickness (t) in which toe crack can occur was 1.2 over. (5) In one side fillet welded T-joint with edge preparation, the burn through led to reduced bending fatigue strength. However, this bending fatigue strength was higher than that of one side fillet welded T-joint without edge preparation and with a larger leg length.

  • PDF

Construction and Calibration Test of a Transmission-type Circular Polariscope for Photoelastic Stress Measurement (광탄성 응력측정을 위한 투과형 원형편광기 제작 및 시험)

  • Baek, T.H.;Koh, S.K.;Na, E.G.;Kim, J.S.;Cha, B.S.;Cho, C.H.
    • Proceedings of the KSME Conference
    • /
    • 2001.11a
    • /
    • pp.437-441
    • /
    • 2001
  • This paper describes the construction of a circular polariscope. Generally, a circular polariscope contains four optical elements and a light source. The first element following the light source is called the polarizer. It converts the ordinary light into plane-polarized light. The second element is a quarter wave plate which converts the plane-polarized light into circularly polarized light. Following the quarter wave plate, a specimen made of transparent photoelastic material is located in a loading device. The second quarter wave plate is set and the last element is the analyzer. These polarizing elements, two quarter wave plates and two polarizing filters, were purchased from the USA. Frames and other structures for holding polarizing filters were machined and assembled to be rotated. Light box, which include four incandescent lamps and two sodium-vapor lamps, was made. In order to proof the function of the newly built polariscope, Tardy compensation test was applied to a rectangular shaped specimen made of poly-carbonate material (PSM1). The error of the fringe constant, which was measured by the newly built polariscope, was within 4.4 percent compared to the standard value of this material. It is possible to make a good quality of polariscope if accurate polarizing filters will be used.

  • PDF

Alternative Sigma Factor HrpL of Pectobacterium carotovorum 35 is Important for the Development of Soft-rot Symptoms

  • Nam, Hyo-Song;Park, Ju-Yeon;Kang, Beom-Ryong;Lee, Sung-Hee;Cha, Jae-Soon;Kim, Young-Cheol
    • Research in Plant Disease
    • /
    • v.17 no.2
    • /
    • pp.111-120
    • /
    • 2011
  • A bacterial artificial chromosome library of Pectobacterium carotovorum 35 was constructed to characterize the genome and to sequence its hrp region. The hrp cluster of P. carotovorum 35 consisted of 26 open reading frames in five operons. A promoter-based green fluorescent protein technology was used to identify the genes regulated by the alternative sigma factor, HrpL, in P. carotovorum 35. The majority of the selected clones contained the hrpJ operon promoter sequence, which harbors a hrp box, but no putative hrp boxes were detected within the promoter sequences of two other hrpL-regulated genes encoding for pectate lyase and large repetitive protein. Although the promoters of five other hrp operons also contained hrp boxes, their expression was not HrpL-dependent in the promoter-based selection in E. coli. However, transcriptional analysis showed that expression from all operons harboring hrp boxes, except for the hrpN operon, was reduced significantly in the hrpL mutant. The severity of soft-rot symptoms when the hrpL mutant was applied to the surface of tobacco leaves, mimicking natural infection, was greatly attenuated. These results indicate that the hrpL gene of P. carotovorum 35 may be involved in the development of soft-rot symptoms.

SEX DIFFERENCES IN BEHAVIOR PROBLEM PATTERNS (문제행동 양상에서의 성차이)

  • Oh, Kyung-Ja;Lee, He-Len;Hong, Kang-E
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
    • /
    • v.2 no.1
    • /
    • pp.125-134
    • /
    • 1991
  • In an attempt to study sex differences in child behavior disorders, 834 clinic-refered children(582 boys and 252 girls) between the ages of 6 to 11 were assessed using CBCL parental form and the data were factor analysed to form empirically derived syndromes for each sex. The analyses yielded eight behavior disorder syndromes for boys and ten, for girls. Six syndromes(aggressive, hyperactive, delinquent, social withdrawal, emotional lability, physical complaints) were found in both sexes while obsessive, depressive and psychotic syndromes were organized differently in boys and girls. There were also considerable differences in item composition of the six syndromes common to box sexes, suggesting that clinical features of common behavior disorders such as aggression and hyperactiveity might be different for boys and girls despite their apparent similarity. The results were discussed in terms of culturally shared attitudes and beliefs concerning sex differences in behaviors.

  • PDF

Study on the Vibration Control of Footbridge by Using Tuned Mass Damper(TMD) (Tuned Mass Damper(TMD)를 이용한 보도교의 진동제어에 대한 연구)

  • 권영록;최광규
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.7 no.6
    • /
    • pp.9-15
    • /
    • 2003
  • This paper describes a vibration control by using tuned mass damper(i.e., TMD) for an existing footbridge. The footbridge is the simple steel box girder bridge with main span length of 47.7m. This bridge has light weight, low damping and the 1st bending frequency of 1.84㎐. Its frequency is close to a walking cycle, which is 2㎐. Therefore the uncomfortable resonant vibrations due to a pedestrian walking have occurred frequently. The vibration control by means of TMD for suppressing the pedestrian induced vibration was conducted. Taking into account economical benefits and the easiness of installation, a compact TMD installed within a handrail was designed. From field tests of the TMD, it was confirmed that the structural damping of the bridge via. the compact TMD was enhanced by 13 times and the resonant vibration due to pedestrian walking was suppressed.