• Genomics & Informatics
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• v.17 no.1
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• pp.9.1-9.5
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• 2019

In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first intron sites by estimating the quantity of rare alleles in the first intron. A basic hypothesis posited herein is that genomic regions carrying more functionally important sites will have a higher proportion of rare alleles. We estimated the proportions of rare single nucleotide polymorphisms with a minor allele frequency < 0.01 located in several histone marks in the first introns of various genes, and compared them with those in other introns and those in 2-kb upstream regions. As expected, rare alleles were found to be significantly enriched in most of the regulatory sites located in the first introns. Meanwhile, transcription factor binding sites were significantly more enriched in the 2-kb upstream regions (i.e., the regions of putative promoters of genes) than in the first introns. These results strongly support our proposal that the first intron sites of genes may have important regulatory functions in gene expression independent of promoters.

• 한국HCI학회:학술대회논문집
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• 2008.02b
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• pp.608-613
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• 2008

Web usability for e-commerce sites becomes a more important issue as e-commerce gains its popularity. As for fresh foods, consumers are especially sensitive to the quality of information during transaction process. Successful fresh food e-commerce sites, such as Wine. com and Tesco, identified regular usability testing as part of key success factors. This paper aims to identify processes for evaluating usability of fresh food e-commerce sites and provide recommendations to improve usability. The study aims to evaluate Web usability of selected Web sites using heuristic evaluation to provide objective Web usability analysis for each transaction process and think aloud method to understand how users actually evaluate the Web site.

• Korean Journal of Plant Taxonomy
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• v.34 no.2
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• pp.87-96
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• 2004

Father, U. Faurie visited Korea (Busan, Incheon, Nampo, Pyongyang, Seoul, Wonsan, Mt. Geumgang of Gangwon-do, and Jeju-do) three times for his plant collections (1901, 1906, and 1907). During his plant explorations, Faurie collected many specimens which were investigated and studied by T. Nakai and H. L$\acute{e}$veill$\acute{e}$ later. Unfortunately all collection sites were simply described in his collection sites in Romanized character, so that it is difficult to pinpoint those sites using the current or old Korean map. From this study, many locality names were reviewed based on his own collections and literatures, and those were listed as the order of his collection dates.

• Bulletin of the Korean Chemical Society
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• v.32 no.3
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• pp.988-992
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• 2011

$CO_2$ adsorption on mineral sorbents has a potential to sequester $CO_2$. This study used a density functional theory (DFT) study of $CO_2$ adsorption on barium oxide (BaO) in the presence of $H_2O$ to determine the role of $H_2O$ on the $CO_2$ adsorption properties on the ($2{\times}2$; $11.05\;{\AA}{\times}11.05\;{\AA}$) BaO (100) surface because BaO shows a high reactivity for $CO_2$ adsorption and the gas mixture of power plants generally contains $CO_2$ and $H_2O$. We investigated the adsorption properties (e.g., adsorption energies and geometries) of a single $CO_2$ molecule, a single $H_2O$ molecule on the surface to achieve molecular structures and molecular reaction mechanisms. In order to evaluate the coordinative effect of $H_2O$ molecules, this study also carried out the adsorption of a pair of $H_2O$ molecules, which was strongly bounded to neighboring (-1.91 eV) oxygen sites and distant sites (-1.86 eV), and two molecules ($CO_2$ and $H_2O$), which were also firmly bounded to neighboring sites (-2.32 eV) and distant sites (-2.23 eV). The quantum mechanical calculations show that $H_2O$ molecule does not influence on the chemisorption of $CO_2$ on the BaO surface, producing a stable carbonate due to the strong interaction between the $CO_2$ molecule and the BaO surface, resulting from the high charge transfer (-0.76 e).

• Journal of Information Technology Services
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• v.14 no.4
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• pp.31-44
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• 2015

Local governments in Korea are involved in three types of online shopping sites : 'direct operation', 'outsourced operation', and 'sales agency.' They are different in terms of the site operator and the charging mechanism among a local government, the site operator, and local producers. This study analyzes their differences in site traffic, local producers' participation, promotion, and partnership. The results from the investigation of 72 shopping sites are the following. First, shopping sites of the 'direct operation' type and the 'outsourced operation' type show significantly higher participation of local producers. Second, the 'marketing agency' type has significantly higher number of promotional activities than the 'oursourced type' which has significantly higher number than the 'direct operation' type. Third, the number of partnerships in the 'marketing agency' type is the highest. The 'direct operation' type is the second and significantly higher than the 'outsourced type.' On the basis of the analysis results, this paper suggests an incubation ecosystem model as a better way of involvement by local governments in online shopping sites.

• Journal of Information Technology Services
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• v.14 no.2
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• pp.177-193
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• 2015

A great number of customers, who want to watch movies usually check out online reviews before choosing what to watch a movie. The most representative online media that customers consult are portal sites and SNS (Social Network Service). Although there have been numerous studies on online eWOM (e-Word of Mouth) and the effects of online media in businesses, it remains a question that which media is best for WOM (Word of Mouth) when selecting movies. This research examines customer's intention for consulting eWOM and for watching movies according to the number and tendency of online replies. We have compared portal sites and SNS about information of movie. The study shows that a large number of positive replies can affect the intention for WOM and choosing movies. Facebook has more influence than portal sites when choosing what to watch when replies consist of large and positive comments. However, there is no difference between the two types of media when they consist of negative comments.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.8
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• pp.3842-3861
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• 2019

In cut throat competition, organizations all over the world try to utilize the immense opportunities the Internet has to offer in almost all of their operations. Today, Social networking sites (SNSs) provide utilities designed to help companies to recruit right personnel. Considering the implication of social media for recruitment at infancy stage in Pakistan and lack of studies related to it, this study aims to investigate the role of different SNSs qualities (Easily navigate, Secure process, Eminence Proficiency, Candidate's Attraction and Network Expedition) in effective E-recruitment (EER). Data were collected through structured questionnaire from employees and managers of major telecom companies of Pakistan. Finally, the result of 355 returned and valid questionnaire with 55% response rate show that the relationship between SNSs qualities and EER is significant. Moreover, results also prove that EER is better than the tradition recruitment and a SNSs comparison show that Facebook is more effective than LinkedIn for EER. The results of this study will help Pakistani companies to develop a successful e-HRM and EER strategy in the current scenario.

• Development and Reproduction
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• v.26 no.1
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• pp.1-12
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• 2022

This study aimed to investigate the signal transduction of phosphorylation sites at the carboxyl (C)-terminal region of equine luteinizing hormone/chorionic gonadotropin receptor (eLH/CGR). The eLH/CGR has a large extracellular domain of glycoprotein hormone receptors within the G protein-coupled receptors. We constructed a mutant (eLH/CGR-t656) of eLH/CGR, in which the C-terminal cytoplasmic tail was truncated at the Phe656 residue, through polymerase chain reaction. The eLH/CGR-t656 removed 14 potential phosphorylation sites in the intracellular C-terminal region. The plasmids were transfected into Chinese hamster ovary (CHO)-K1 and PathHunter Parental cells expressing β-arrestin, and agonist-induced cAMP responsiveness was analyzed. In CHO-K1 cells, those expressing eLH/CGR-t656 were lower than those expressing eLH/CGR wild-type (eLH/CGR-wt). The EC₅₀ of the eLH/CGR-t656 mutant was approximately 72.2% of the expression observed in eLH/CGR-wt. The maximal response in eLH/CGR-t656 also decreased to approximately 43% of that observed in eLH/CGR-wt. However, in PathHunter Parental cells, cAMP activity and maximal response of the eLH/CGR-t656 mutant were approximately 173.5% and 100.8%, respectively, of that of eLH/CGR-wt. These results provide evidence that the signal transduction of C-terminal phosphorylation in eLH/CGR plays a pivotal role in CHO-K1 cells. The cAMP level was recovered in PathHunter Parental cells expressing β-arrestin. We suggest that the signal transduction of the C-terminal region phosphorylation sites is remarkably different depending on the cells expressing β-arrestin in CHO-K1 cells.

• Economic and Environmental Geology
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• v.27 no.1
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• pp.49-63
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• 1994

Paleomagnetic study of Tertiary rocks in Pohang area has been carried out to determine the characteristic directon of natural remanent magnetization, the position of paleomagnetic pole, the stratigraphic correlation, and the tectonic movement. A total of 196 specimens was collected from 5 sites in the Pohang Basin, 19 sites in the Janggi Basin, and 10 sites in the Eoil Basin, respectively. The mean declination and inclination of 4 sites (3 sites in the Yonil Group and 1 site in the Yonil Basalt) are $-3.2^{\circ}$ and $54.3^{\circ}$, and yield the paleomagnetic pole position $86.9^{\circ}N$ and $7.7^{\circ}E$. These are the characteristic direction and pole position of Miocene Epoch by comparison with contemporary Eurasian and Chinese data. The characteristic direction and pole position of remaining 30 sites are $47.6^{\circ}$ and $57.5^{\circ}$, and $52.3^{\circ}N$ and $201.5^{\circ}E$, respectively. These show clockwise rotation of $50.8^{\circ}$ with respect to the Miocene ones resulted by a tectonic movement before the deposition of the Hakjeon Formation of the Yonil Group about 15~16 Ma in the study area. The mechanism of the clockwise rotation is considered to be the dextral movement of the Yangsan Fault presumably caused by the opening of the East Sea. The Yonil Basalt is reclassified into pre- and post-deposition of the Yonil Group, i.e. the former is early Miocene and the latter late Miocene.

• The Journal of the Korea Contents Association
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• v.4 no.3
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• pp.21-40
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• 2004

Trade portal site is one of the tools which make it possible for small and medium-sized enterprises(SMEs) to manage international trade activities more efficiently by using the newest information and telecommunication technology. So Korean SMEs should utilize trade portal sites more actively to promote global competitive power. Based on the theory of service quality and existing researches related to using information technology, this paper analyzed the primary factors which affect user's utilization satisfaction in using trade portal sites. According to the results of the empirical study on actual users of the representative trade portal sites by multiple regression analysis, the primary factors, such as service quality, government policy and cost factor have affected user's utilization satisfaction in using trade portal sites. And user's utilization satisfaction have positive effect on continuous using intention. These research results will provide many useful insights to trade portal site managers, e-trade system developers and government policy makers.