• 보건교육건강증진학회지
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• 제22권2호
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• pp.97-110
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• 2005

Objectives: Recent studies have shown that tailored messages for cancer screening to the beliefs and stage of cancer screening behavior of individual women increases the take-up probability. Many studies on cancer screening have used the Transtheoretical Model (TTM) to identify variables associated with cancer screening behavior. This study was carried out to identify the cognitive-behavioral factors associated with stomach cancer screening among women aged 40 years and over, and to develop and evaluate a tailored educational program for stomach cancer screening by stages of change. Methods: Building on the TTM constructs, we conducted a quasi-experimental study(N=283) to test the effectiveness of a tailored educational program for endoscopic stomach cancer screening. We carried out pre and post tests in the experimental group(N=162) and the control group(N=121), and the experimental group was subdivided into an on-line group(N=81) and an off-line group(N=81) by educational methodology using e-mail and the postal service. We used the chi-square test, trend test, and paired t-test to test the effectiveness of the program for stomach cancer using a tailored stage-matched messages. Results: To examine the effectiveness of the program for stomach cancer screening by the tailored stage-matched messages, the stage-matched materials were offered to the experimental group(N=162) four times for 4 weeks. The stage-matched materials consisted of the four types for stomach cancer. The tailored message was effective in changing the cognitive-behavioral factors, such as experience process, behavior process, con opinion for stomach cancer, self-efficacy, and the behavioral stages for stomach cancer screening. The stomach cancer screening adherence was higher for the stage-matched materials using postal mail than for those using e-mail. Conclusion: To improve the stomach cancer screening rate, the use of tailored messages for stomach cancer screening will be generated using an expert system. Therefore the implementation of tailored educational program will be supported a partnership between public and private health organizations and increasing awareness of the necessity of community-based interventions.

• 한국전자거래학회지
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• 제17권4호
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• pp.117-140
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• 2012

본 연구는 경쟁분석을 통해 효율적인 벤치마킹 대상을 파악 후 개선점을 도출하는 컨설팅기법의 활용에 관한 연구이다. 경쟁자 분석을 위해 상대적 효율성 분석도구인 DEA(Data Envelopment Analysis, 자료포락분석)을 이용하여 컨설팅현장 또는 기업 내부에서 효율적으로 적용이 가능한 컨설팅 분석기법을 개발하여 기존 경쟁분석기법과 비교하여 제시하였다. 본 연구는 먼저 문헌고찰을 통해 컨설팅 방법론의 경쟁분석 기법과 상대적 효율성 분석 기법인 DEA에 대한 기존학자들의 연구를 살펴보고 DEA를 기반으로 한 경쟁분석인 다차원효율분석방법을 제시한 후 이 분석 방법의 적합성 및 실용성을 확인하기 위해 공기업 "A"를 대상으로 사례 연구를 실시하였다.

• 한국전자거래학회지
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• 제17권4호
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• pp.17-37
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• 2012

소셜 네트워크 서비스(SNS) 등 정보통신 기술의 빠른 진화는 사용자들 간의 소통과 응집을 가능하게 하는 순기능과 허위 사실의 유포나 소수의 여론 독점 등 역기능 요소로써 소비자의 문제행동을 유발시킬 가능성이 있다. 소비자의 문제행동이 점차 증가하고 있으며 이에 따라 많은 사업자들이 피해를 입고 있음에도 불구하고 소비자 문제행동에 관한 선행연구들이 미미하여 체계적인 대응 전략 마련이 어려운 상황이다. 따라서 본 연구에서는 소비자 문제행동에 대한 선행연구와 구조 기반 신뢰 연구에 기반하여 소비자의 문제행동 방어전략을 모색하였다. 본 연구를 통해 소비자의 비윤리적 행위의 영역에 이르기 까지 연구의 영역을 넓힘과 동시에 실무적으로는 소비자 문제행동에 대응한 사업자 전략 및 제도적 장치 보완에 기여할 수 있을 것으로 판단한다.

• 한국동물위생학회지
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• 제44권4호
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• pp.185-194
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• 2021

Polyglutamine extension in the coding sequence of mutant huntingtin causes neuronal degeneration associated with the formation of insoluble polyglutamine aggregates in Huntington's disease (HD). Mutant huntingtin can form aggregates within the nucleus and processes of neurons possibly due to misfolding of the proteins. To better understand the mechanism by which an elongated polyglutamine causes aggregates, we have developed an in vitro binding assay system of polyglutamine tract from truncated huntingtin. We made GST-HD exon1 fusion proteins which have expanded polyglutamine epitopes (e.g., 17, 23, 32, 46, 60, 78, 81, and 94 CAG repeats). In the present emergence of new study adjusted nanotechnology on protein chip such as surface plasmon resonance strategy which used to determine the substance which protein binds in drug discovery platform is worth to understand better neurodegenerative diseases (i.e., Alzheimer disease, Parkinson disease and Huntington disease) and its pathogenesis along with development of therapeutic measures. Hence, we used strengths of surface plasmon resonance (SPR) technology which is enabled to examine binding specificity and explore targeted molecular epitope using its electron charged wave pattern in HD pathogenesis utilize conjugated mutant epitope of HD protein and its interaction whether wild type GST-HD interacts with mutant GST-HD with maximum binding affinity at pH 6.85. We found that the maximum binding affinity of GST-HD17 with GST-HD81 was higher than the binding affinities of GST-HD17 with other mutant GST-HD constructs. Furthermore, our finding illustrated that the mutant form of GST-HD60 showed a stronger binding to GST-HD23 or GST-HD17 than GST-HD60 or GST-HD81. These results indicate that the binding affinity of mutant huntingtin does not correlate with the length of polyglutamine. It suggests that the aggregation of an expanded polyglutamine might have easily occurred in the presence of wild type form of huntingtin.

• Journal of Preventive Medicine and Public Health
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• 제56권5호
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• pp.449-457
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• 2023

Objectives: This study investigated the association between baseline exposures to particulate matter with a diameter <2.5 microns (PM_2.5) and subsequent temporal changes in PM_2.5 exposure with the incidence of type 2 diabetes among Royal Thai Army personnel. Methods: A retrospective cohort study was conducted using nationwide health check-up data from 21 325 Thai Army personnel between 2018 and 2021. Multilevel mixed-effects parametric survival statistics were utilized to analyze the relationship between baseline (i.e., PM_2.5-baseline) and subsequent changes (i.e., PM_2.5-change) in PM_2.5 exposure and the occurrence of type 2 diabetes. Hazard ratios (HRs) and 95% confidence intervals (CIs) were employed to assess this association while considering covariates. Results: There was a significant association between both PM_2.5 baseline and PM_2.5-change and the incidence of type 2 diabetes in a dose-response manner. Compared to quartile 1, the HRs for quartiles 2 to 4 of PM_2.5-baseline were 1.11 (95% CI, 0.74 to 1.65), 1.51 (95% CI, 1.00 to 2.28), and 1.77 (95% CI, 1.07 to 2.93), respectively. Similarly, the HRs for quartiles 2 to 4 of PM_2.5-change were 1.41 (95% CI, 1.14 to 1.75), 1.43 (95% CI, 1.13 to 1.81) and 2.40 (95% CI, 1.84 to 3.14), respectively. Conclusions: Our findings contribute to existing evidence regarding the association between short-term and long-term exposure to PM_2.5 and the incidence of diabetes among personnel in the Royal Thai Army.

• 한국환경보건학회지
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• 제46권5호
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• pp.525-531
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• 2020

Objectives: This study was performed to identify the epidemiological features of a food poisoning outbreak in a company cafeteria located in Chungcheongnam-do Province, Korea in June of 2020 and to suggest preventive measures for a similar incidence. Methods: A total of 84 patients with acute gastroenteritis were examined. Environmental samples were obtained from 16 food handlers, six food utensils, 135 preserved foods served over three days and nine menus, and six drinking water samples. These are analyzed to detect viruses and bacteria. Results: Ninety-four out of the 402 people who were served meals (23.4%) predominantly showed symptoms of diarrhea, and the number was over 3 times. Among the 84 patients under investigation, 17 cases (20.2%) were positive for Enteropathogenic E. coli (EPEC) and 18 cases were positive for Clostridium (C.) perfringens (21.4%). Based on the investigation, it was concluded that the main pathogens were EPEC and C. perfringens. For EPEC, it was detected in three of the food service employees and in the preserved food and curry rice. The results of pulsed field gel electrophoresis indicate that all EPEC cases are closely related except for one food service employee. Assuming that isolated EPEC originated from the preserved food, the incubation period is about 25 hours. The origin of the C. perfringens was not determined as it was not detected in the food service employees or environmental samples. Conclusions: This case suggests that food provided in group food service centers must be thoroughly managed. In addition, identifying the pathogens in preserved food is very important for tracing the causes of food poisoning, so food must be preserved in an appropriate condition. To prevent similar food poisoning cases, analyzing cases based on epidemiological investigation and sharing the results is needed.

• 한국비블리아학회지
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• 제6권1호
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• pp.133-160
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• 1984

The main purpose of the present study is to survey the major abstracting bulletins of national nature in Korea, to define such problem areas as lacunae, duplicates and limitation in coverage in the abstracting services currently available in Korea, and to make some suggestions for action for improving the abstracting services in the light of general principles and the tradition and situations unique to Korea. The major conclusions reached at this study are summarised as follows: (A) A new abstracting bulletin of general nature covering the whole field needs to be created in each of the following fields where no established abstracting service is available for the outcome of research and development activities in Korea. (1) Language (2) Religion (3) Art (4) Language (5) Literature (6) History (B) A new specialised abstracting bulletin needs to be created in each of the following fields of science where abstracting services limited in coverage are partially available. (a) Statistics (b) Sociology (c) political science (d) Public administration (e) Law (f) Folk lore (g) Military science (2) Pure sciences (a) Mathematics (b) Chemistry (c) Astronomy (d) Geology (e) Mineralogy (f) Life sciences (g) Botany (h) Zoology (3) Applied sciences (a) Agriculture (b) Architectural engineering (c) Mechanical engineering (d) Electrical engineering (e) Chemical engineering (f) Manufacturing industry (g) Domestic science (C) Publication of the abstracting bulletins suggested in (A) and (B) above may be ideally carried on by a qualified learned society established in the respective field. and should be financially supported by the public fund under the provisions of Art. 27 of the Research Promotion Act of 1979. (D) The current practice of adding the author's abstract and keywords to each of the records of the "Doctoral Theses in Humanities and Social Sciences" part of the" Catalogue of Doctoral and Master's Theses Submitted to the Universities in Korea" published by the National Assembly Library should be applied to all the other parts, i. e. to the parts of the "Master's Theses in Humanities and Social Sciences" and of the "Doctoral and Master's Theses in Natural Sciences': which will not only increase the Catalogue's use value but also discourage appearance of various theses abstracts of individual academic institutions such as the" Abstracts of the Doctoral and Master's Theses Submitted to Korea Advanced Institute of Science and Technology" which will in turn reduce inefficiency involved in the abstracting services at national level. (E) A general abstracting bulletin covering most part of the outcome of research and development activities in Korea other than that covered by the existing abstracts needs to be created to be temporarily. used till the abstracting journals suggested in this study will be fully available. A realistic way of having such a bulletin may be to expand the present coverage of "The Abstracts of the Reports of the Government-sponsored Projects" currently published by Korean Research Foundation.

• 한국컴퓨터정보학회논문지
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• 제12권3호
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• pp.225-234
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• 2007

본 연구는 오늘날 뉴테러리즘 환경 하의 테러대응체제를 구축하기 위하여, 그 중에서도 특히 테러 피해의 최소화를 위한 가장 효과적인 대응책 중의 하나인 예방홍보에 대한 중요성을 일깨우고, 나아갈 방향을 제시하여 준다는 목적을 연구의 출발점으로 삼아 이를 법사회학적 측면에서 고찰하였다. 공공매체를 통한 정부기관의 홍보는 국민들의 참여를 촉진시키고 인식을 향상시키는데 중요한 역할을 수행하게 된다. 따라서 테러발생의 환경 변화에 따른 테러예방을 강화하기 위해서는 고도 정보화 사회에 적합한 테러예방 홍보수단으로서 국민에게 한 발짝 다가설 수 있는 적극적인 방안이 모색되어야 한다. 이를 위한 방안으로써 본 연구에서는 우선적으로 테러 대응체제로서 경찰조직과 공중과의 관계성에 대하여 논의하였으며, 양자의 관계정립의 활성화 통하여 효율적인 테러예방을 위한 홍보방안들에 대해서 논의하였다. 여기에는 오늘날 인터넷이 갖는 장점을 최대한 활용하여 어떻게 하면 테러예방 홍보효과를 극대화할 것인가에 궁극적인 목적을 가지고 e-CRM의 도입 등을 통한 운영방안을 제시하였다. 또한 대국민 홍보활동을 강화하여 언론매체 등을 활용하여 정부차원의 대테러 정보자료의 배포 범위의 확대를 통한 정보서비스 활동의 필요성과 기타 테러예방 홍보의 관리전략들을 제시하였다.

• 정보처리학회논문지D
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• 제15D권2호
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• pp.223-234
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• 2008

최근 웹 서비스 분야는 기업내외의 효율적인 통합 환경을 제공해 주면서 웹 서비스의 도입을 원하는 업체가 증가하고 있다. 또한 웹 서비스가 발전하면서 새로운 비즈니스 모델이 등장하고, 웹 서비스로 인해 국내 기업 환경 및 e-비즈니스 환경이 변화하고 있다. 유사한 기능을 제공하는 웹 서비스가 증가함에 따라 사용자의 요구에 가장 적합한 서비스를 찾는 방법이 더욱 중요시 되고 있다. 많은 유사한 웹 서비스들 가운데 하나를 선택해야 할 때, 서비스 사용자는 일반적으로 웹 서비스의 품질 정보를 필요로 하게 된다. 그러나 웹 서비스의 광고 QoS 정보는 항상 신뢰성이 있지는 않다는 문제점이 있다. 서비스 제공자가 더 많은 사용자들을 끌어들이기 위해 부정확한 QoS 정보를 게시하거나, 게시된 QoS 정보가 오래 되었을 수도 있다. 따라서 현재의 사용자들이 웹 서비스로부터 받는 QoS를 평가하고 이러한 평가를 공유하는 중개자의 존재는 새로운 사용자들에게 가치 있는 정보를 제공할 수 있다. 본 논문에서는 서비스 사용자의 입장에서 사용자가 원하는 최적의 품질을 제공하는 서비스를 찾도록 도와주는 에이전트 기반 품질 브로커 아키텍처를 제안한다. 동적으로 웹 서비스를 선정하는 아키텍처를 사용자에 제공함으로서 사용자의 품질 요구 변경 문제를 해결할 수 있다. 즉 사용자는 품질 브로커 서버에 연결된 UDDI 브라우저를 통해 최적의 품질 척도를 제공하는 서비스를 검색할 수 있다. 또한 각 서비스의 품질척도 값 결정에는 사용자 개입이 최대한 배제된다. 기존 선정 아키텍처에서는 사용자의 주관적 서비스 등급 선정으로 객관적 평가가 어려웠으나, 에이전트가 사용자 위치에서 모니터링 한 바인딩 정보를 통한 품질 척도 값 결정으로 객관성을 확보할 수 있다. 즉, 제공자들이 제공하지 못하는 서비스의 QoS 정보를 사용자측 에이전트들의 피드백으로 인한 QoS 정보 공유로 해결하고자 한다.

• 한국동물위생학회지
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• 제34권1호
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• pp.45-54
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• 2011

This study was conducted to investigate the distribution of Salmonella spp. from pigs and cattle in slaughterhouse, the antimicrobial resistance pattern and the prevalence of resistance genes of isolates. A total of 640 fecal samples from pigs and cattle in slaughterhouse were collected for isolation of Salmonella spp.. Isolation rate was revealed as 15% in pigs and 1.6% in cattle. As result of serotyping, group B (56.6%) were identified as most common in pigs and cattle isolates, in order of group C (24.5%) and group E (15.1%). S. Typhimurium (50.9%) was most common serotype. The major serotypes were in order of S. Rissen and S. London (11.3%) and S. Riggil (7.6%). In antimicrobial test, all isolates were demonstrates susceptibility to nitrofurantoin. But isolates were revealed resistance other antibiotics in order of tetracycline (64.6%), streptomycin (68.3%), ampicillin and amoxicillin (56.3%) and spectinomycin (47.9%). With polymerase chain reaction, antimicrobial resistance gene strA (75.0%) and aadA1 (3.1%) were detected in streptomycin resistance isolates and tetA (94.3%) and tetB (11.3%) gene were detected in tetracycline resistant isolates, but tetG was not detected. Class 1 integron gene was detected in all Salmonella isolates.