• The Korean Journal of Food And Nutrition
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• v.18 no.4
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• pp.367-372
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• 2005

Antimicrobial effects of the extracts from Castanea crenata leaf were investigated. The antimicrobial effects of methanol extract (8 mg, 20 mg) of 0.2 g and 0.5 g. eq. of Castanea crenata leaf was stronger than that of 0.65 mg of benzoic acid against Gram(+) bacteria such as Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Leuconostoc mesenteroides and Bacillus subtilig and Gram(-) bacteria such as Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa. Growth inhibition of various microorganisms was observed in Castanea crenata leaf, therefor the Castanea crenata leaf were solvent fractionated. The ethyl acetate-soluble acidic and phenolic fraction were showed remarkable antimicrobial activity against microorganisms tested. The acidic fraction was purified with silica gel adsorption column chromatography, Sephadex LH-20 column chromatography and HPLC, subsequantly. The antimicrobial active substance isolated from the acid fraction of Castanea crenata leaf was characterized as stigmast-5-en-3-ol($\beta$-sitosterol) by MS and NMR analysis.

• Journal of Korean Society of Forest Science
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• v.95 no.5
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• pp.556-561
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• 2006

This study was conducted to choose end-members and tracers for application of End Member Mixing Analysis (EMMA) model for the coniferous forest catchment, Gwangneung Gyeongi-do near Seoul metropolitan of South Korea (N $37^{\circ}$ 45', E $127^{\circ}$ 09'). This coniferous forest of Pinus Korainensis and Abies holophylla was planted at stocking rate of $3.0stems\;ha^{-1}$ in 1976. Thinning and pruning were carried out two times in the spring of 1996 and 2004 respectively. We monitored two successive rainfall events during ten days from June 26, 205 to July 5, 2005. Two storm events were selected to determine the end members and natural traces for hydrograph separation. The event 1 amounts to 161.9 m for two days from June 26 to 27, 2005. The event 2 precipitates to 139.2 mm for one day of July 1, 205. Throughfall, groundwater, soil water and stream water of the two events above were sampled through the bulk and automatic sampler. Their chemical properties were analyzed for prediction of the main tracer. The end members that contribute to the stream runoff were identified from the three components including groundwater, soil water and throughfall. Each component and stream water in the two events formed the suitable mixing diagram in case of chloride-nitrate ion and sulfate-potassium ion. Especially, chloride-nitrate ion was found to be the most suitable tracers for EMMA model in the two events.

• Journal of Broadcast Engineering
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• v.24 no.5
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• pp.827-835
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• 2019

In the pooling stage of a full reference image quality assessment (FR-IQA) technique, the global perceived quality for any distorted image is usually measured from the quality of its local image patches. But all the image patches do not have equal contribution when estimating the overall visual quality since the degree of degradation on those patches depends on various considerations i.e., types of the patches, types of the distortions, distortion sensitivities of the patches, saliency score of the patches, etc. As a result, weighted pooling strategy comes into account and different weighting mechanisms are used by the existing FR-IQA methods. This paper performs a thorough analysis and proposes a novel weighting function by considering the luminance adaptation as well as the visual saliency effect to offer more appropriate local weights, which can be adopted in the existing FR-IQA frameworks to improve their prediction accuracy. The extended experimental results show the effectiveness of the proposed weighting function.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.519-519
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• 2016

Upper Chenab Canal (UCC) is a non-perennial canal in Punjab Province of Pakistan which provides irrigation water only in summer season. Winter and summer are two distinct cropping season with an average rainfall of about 161 mm and 700 mm respectively. Wheat-rice is common crop rotation being followed in the UCC command area. During winter season, groundwater and rainfall are the main sources of irrigation while canal and ground water is used to fulfil the crop water requirements (CWR) during summer. The objective of current study is to estimate how the irrigation water requirements (IWR) of the two crops are going to change under different conditions of temperature and rainfall. For this purpose, 12 different climatic scenarios were designed by combining the assumptions of three levels of temperature increase under dry, normal and wet conditions of rainfall. Weather records of 13 years (2000-2012) were obtained from PMD (Pakistan Meteorological Department) and CROPWAT model was used to simulate the IWR of the crops under normal and scenarios based climatic conditions. Both crops showed a maximum increase in CWR for temperature rise of $+2^{\circ}C$ i.e. 8.69% and 6% as compared to average. Maximum increment (4.1% and 17.51% respectively) in IWR for both wheat and rice was recorded when temperature rise of $+2^{\circ}C$ is coupled with dry rainfall conditions. March & April during winter and August & September during summer were the months with maximum irrigation requirements. Analysis also showed that no irrigation is needed for rice crop during May and June because of enough rainfall in this area.

• Journal of the Society of Naval Architects of Korea
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• v.31 no.4
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• pp.66-72
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• 1994

For the reliable prediction of maneuverability of a ship, lots of captive model tests have been carried out for over 10 years. But the parameters appearing in the mathematical model are so versatile and showing complex characteristics, and it is still hard to establish the useful formulae that we can adopt directly in the design stage. In this paper, the most important parameters in the mathematical model. i.e.($1-\omega_P$) the effective wake fraction at propeller, and $\delta_R(\beta_R)$), the effective rudder inflow angles are investigated by the captive model tests at the circulating water channel. The model is tested at designed speed and at low speed, and the drafts at both full load and ballast load conditions are taken. Propeller thrusts and rudder normal forces are measured at the given drift angle and propeller revolution. These forces are used for the analysis of the effective flow velocity or flow direction, to the propeller or rudder.

• Korean Journal of Human Ecology
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• v.6 no.2
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• pp.1-12
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• 2003

This study is designed to analyse the difference between consciousness and behaviors for environmental preservation dependant on independent variables and to identify factors that affect the behaviors of environmental preservation. For this study, a questionnaire that included measurements of environmental preservation consciousness and behaviors was produced as a studying tool. Targets were 520 boy and girl students in the second grade of two high schools in Gwangju and three high schools in small districts of Chonnam Province and 482 questionnaires were distributed for the analysis. The data collected was analysed using SAS Program Package to obtain frequency, percentage, standard deviation, and correlation and T-Test One-way ANOVA, Duncan's M411ip1e Range Test, Multiple Regression were performed. The results of the analyses are as follows : 1. Overall, environmental preservation consciousness is higher than preservation behaviors. Interest in air pollution is the highest in both environmental preservation consciousness and behaviors and it is low in recycling. 2. The environmental preservation consciousness has a significant difference dependant on sex, regions, order of birth, educational background of parents and income level. the performing degree of environmental education, consciousness about kinds of environmental preservation, and whether the learning of theory and practice of environmental education is performed. 3. The environmental preservation behaviors has a significant difference dependant on regions, educational background of mother, mother's job, income level, acquiring of information, performing degree of environmental education and consciousness of kinds of environmental education. 4. Variables that affect environmental preservation behavior are environmental preservation consciousness, acquiring information, performing degree of environmental education and awareness of environmental preservation. Their power of explanation is 15%.

• Journal of Microbiology and Biotechnology
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• v.31 no.10
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• pp.1401-1408
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• 2021

This study examined whether the oral administration of low-molecular-weight collagen peptide (LMCP) containing 3% Gly-Pro-Hyp with >15% tripeptide (Gly-X-Y) content could ameliorate osteoarthritis (OA) progression using a rabbit anterior cruciate ligament transection (ACLT) model of induced OA and chondrocytes isolated from a patient with OA. Oral LMCP administration (100 or 200 mg/kg/day) for 12 weeks ameliorated cartilage damage and reduced the loss of proteoglycan compared to the findings in the ACLT control group, resulting in dose-dependent (p < 0.05) improvements of the OARSI score in hematoxylin & eosin (H&E) and Safranin O staining. In micro-computed tomography analysis, LMCP also significantly (p < 0.05) suppressed the deterioration of the microstructure in tibial subchondral bone during OA progression. The elevation of IL-1β and IL-6 concentrations in synovial fluid following OA induction was dose-dependently (p < 0.05) reduced by LMCP treatment. Furthermore, immunohistochemistry illustrated that LMCP significantly (p < 0.05) upregulated type II collagen and downregulated matrix metalloproteinase-13 in cartilage tissue. Consistent with the in vivo results, LMCP significantly (p < 0.05) increased the mRNA expression of COL2A1 and ACAN in chondrocytes isolated from a patient with OA regardless of the conditions for IL-1β induction. These findings suggest that LMCP has potential as a therapeutic treatment for OA that stimulates cartilage regeneration.

• Journal of Breast Cancer
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• v.21 no.4
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• pp.391-398
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• 2018

Purpose: The aim of this study was to investigate the association of telomere length with breast cancer risk. We simultaneously explored the association between telomerase reverse transcriptase gene polymorphisms and telomere length. Methods: We used real-time quantitative polymerase chain reaction to measure relative telomere length (RTL) in genomic DNA extracted from peripheral blood from 183 breast cancer cases and 191 healthy controls. Genotyping was performed using the Sequenom MassARRAY platform. Results: Our results show that breast cancer patients had significantly shorter RTLs than control subjects (p<0.05). When the RTLs were categorized into tertiles, we found that the lowest RTL was significantly associated with increased breast cancer risk compared with the highest RTL (odds ratio [OR], 2.33; 95% confidence interval [CI], 1.40-3.90; p=0.001). Subgroup analyses indicated that risk of breast cancer was also significantly increased in the lowest RTL compared with the highest RTL in age >40 years (OR, 2.41; 95% CI, 1.31-4.43;p=0.005), body mass index ${\leq}24kg/m^2$ (OR, 2.81; 95% CI, 1.55-5.10; p=0.001), and postmenopausal women (OR, 3.94; 95% CI, 1.63-9.51; p=0.002), respectively. In addition, individuals with the AA genotype of rs2853677 have longer telomeres than those of breast cancer patients with the AG genotype (p=0.011). Conclusion: Our results suggest that shorter RTL was associated with an increased risk of breast cancer. An association was found between the AA genotype of rs2853677 and longer RTLs in the case group. Functional studies are warranted to validate this association and further investigate our findings.

• Food Science of Animal Resources
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• v.38 no.6
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• pp.1144-1154
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• 2018

Both the calcium and collagen in bone powder are hard to be absorbed by the body. Although enzymatic hydrolysis by protease increased the bio-availability of bone powder, it was a meaningful try to further increase $Ca^{2+}$ release, oligopeptide formation and antioxidant activity of the sheep bone hydrolysate (SBH) by lactic acid bacteria (LAB) fermentation. Lactobacillus helveticus was selected as the starter for its highest protease-producing ability among 5 tested LAB strains. The content of liberated $Ca^{2+}$ was measured as the responsive value in the response surface methodology (RSM) for optimizing the fermenting parameters. When SBH (adjusted to pH 6.1) supplemented with 1.0% glucose was inoculated 3.0% L. helveticus and incubated for 29.4 h at $36^{\circ}C$, $Ca^{2+}$ content in the fermented SBH significantly increased (p<0.01), and so did the degree of hydrolysis and the obtaining rate of oligopeptide. The viable counts of L. helveticus reached to $1.1{\times}10^{10}CFU/mL$. Results of Pearson correlation analysis demonstrated that LAB viable counts, $Ca^{2+}$ levels, obtaining rates of oligopeptide and the yield of polypeptide were positively correlated with each other (p<0.01). The abilities of SBH to scavenge the free radicals of DPPH, OH and ABTS were also markedly enhanced after fermentation. In conclusion, L. helveticus fermentation can further boost the release of free $Ca^{2+}$ and oligopeptide, enhance the antioxidant ability of SBH. The L. helveticus fermented SBH can be developed as a novel functional dietary supplement product.

• Journal of Information Processing Systems
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• v.15 no.4
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• pp.865-889
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• 2019

The need for cyber resilience is increasingly important in our technology-dependent society where computing devices and data have been, and will continue to be, the target of cyber-attackers, particularly advanced persistent threat (APT) and nation-state/sponsored actors. APT and nation-state/sponsored actors tend to be more sophisticated, having access to significantly more resources and time to facilitate their attacks, which in most cases are not financially driven (unlike typical cyber-criminals). For example, such threat actors often utilize a broad range of attack vectors, cyber and/or physical, and constantly evolve their attack tactics. Thus, having up-to-date and detailed information of APT's tactics, techniques, and procedures (TTPs) facilitates the design of effective defense strategies as the focus of this paper. Specifically, we posit the importance of taxonomies in categorizing cyber-attacks. Note, however, that existing information about APT attack campaigns is fragmented across practitioner, government (including intelligence/classified), and academic publications, and existing taxonomies generally have a narrow scope (e.g., to a limited number of APT campaigns). Therefore, in this paper, we leverage the Cyber Kill Chain (CKC) model to "decompose" any complex attack and identify the relevant characteristics of such attacks. We then comprehensively analyze more than 40 APT campaigns disclosed before 2018 to build our taxonomy. Such taxonomy can facilitate incident response and cyber threat hunting by aiding in understanding of the potential attacks to organizations as well as which attacks may surface. In addition, the taxonomy can allow national security and intelligence agencies and businesses to share their analysis of ongoing, sensitive APT campaigns without the need to disclose detailed information about the campaigns. It can also notify future security policies and mitigation strategy formulation.