• Proceedings of the Korean Geotechical Society Conference
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• 2005.03a
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• pp.838-845
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• 2005

Slope stability analyses have been carried out to investigate surcharge loading effects. Finite Element Analysis (FEA) involves the stress-strain behaviour of soils achieving reasonably accurate and useful results of slope stability analysis. Therefore, in this study, one of well known FEA programs, SIGMA/W, has been used to do slope stability analyses with respect to various upper slope angles and surcharge loadings. Factor of Safety(FS) exponentially decreases and significantly good correlation with the increased slope angle for upper slopes. As the surcharge loading increases from 10 t/m to 90 t/m for nail-reinforced slopes, the FS in fully saturated condition decreases from 42% to 47% and from 17% to 25% for relatively low and high strength of soils, respectively, than in dry condition.

• International Journal of Concrete Structures and Materials
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• v.19 no.1E
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• pp.41-48
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• 2007

Addition of latex to concrete is known to increase its durability and permeability. The purpose of this study is to analyze air void systems in latex-modified concretes using a reasonable and objective method of image analysis with such experimental variables as water-cement (w/c) ratios, latex contents (0%, 15%) and cement types (ordinary portland cement (OPC), high-early strength (HES) cement and very-early strength (VES) cement). The results are analyzed by spacing factor, air volume (content) after hardening, air void distribution and structure. Additionally, air void systems and permeability of latex-modified concrete (LMC) are compared by a correlation analysis. The results are as follows. The LMC of the same w/c ratio showed better air entraining (AE) effect than OPC with AE water reducer. The VES-LMC showed that the quantity of entrained air below $100{\mu}m$ increased more than four times. For the case of HES-LMC, microscopic entrained air between the range of 50 to $500{\mu}m$ increased greater than 7 times even in the absence of anti-foamer. Although spacing factor was measured rather low, the permeability of latex-modified concrete was good. It is construed that air void system does not have a considerable effect on the property of latex-modified concrete, but latex film (membrane) has a definite influence on the durability of LMC.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2000.04a
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• pp.81-88
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• 2000

Unlike structures in the air, the vibration analysis of a submerged or floating structure such as offshore structures or ships is possible only when the fluid-structure interaction is understood, as the whole or part of the structure is in contact with water. Specially, the importance of the added mass is not necessary to say like the submerged vehicle, all of the hull body, is positioned in the water. This paper introduce two method to find natural frequency in consideration of fluid-structure modal coupled vibration analysis. The purpose of this study is to analyze of the vibration characteristic of submerged vehicle to obtain the anti-vibration design data, which could be used in the preliminary design stage data. Underwater pressure hull of submerged vehicle is used as the model of this study. The F.E.M model is meshed by shell and beam element. Also, considering of the inner hull weight, mass element is distributed in the direction of hull length. Numerical calculations are accomplished using the commercial B.E.M code. The characteristics of natural frequency(eigenvalues), mode shape(eigenvectors) and frequency-displacement response are analyzed. The results of this study will be used as the useful design data in preliminary anti-vibration design stage.

• Journal of The Korean Society of Agricultural Engineers
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• v.60 no.3
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• pp.15-25
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• 2018

Estimating the reference evapotranspiration is an important factor to consider in irrigation system design and agricultural water use. However, there is a limitation in using the FAO Penman-Monteith (FAO P-M) equation, which requires various meteorological data. The purpose of this study is to compare three reference evapotranspiration (ETo) equations in the case of meteorological data missing for 11 study weather stations. Firstly, the FAO P-M equation is used for reference potential evapotranspiration estimation with the actual solar radiation data $R_n$ and the actual vapor pressure $e_a$. Then, in the case of $R_n$, and $e_a$ are missed, the reference evapotranspirations applying FAO P-M, Priestley-Taylor (P-T), Hargreaves (HG) equation were calculated using other meteorological factors. Secondly, MAE, RMSE, $R^2$ were calculated to compare ETo relationship from the ETo equations. From the results, ETo with Hargreaves equation in coastal areas and the Priestley-Taylor equation in the inland areas showed relatively high correlation with FAO P-M when $e_a$ data is missed. In the case of $R_n$ data is missed or two weather data, $e_a$, and $R_n$ data are all missed, $R^2$ value in Priestley-Taylor equation was highest in coastal areas, and $R^2$ values in Hargreaves equation were the high values for 7 inland areas. The results of sensitivity analysis showed that net radiation was the most sensitive for P-T and HG equation, and for FAO P-M, the most sensitive factor was net radiation and relative humidity, air temperature and wind speed were follows. Therefore, in considering of the accessibility to the coast, the types of the missing wether data, and the correlation and the magnitude of error, the reference evapotranspiration equations would be selected in sense of different conditions.

• Atmosphere
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• v.32 no.4
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• pp.307-322
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• 2022

A drone has recently got attention as an instrument for weather observation in lower atmosphere because it can produce the high spatiotemporal resolution weather data even though the weather phenomenon is inaccessible. Sea fog is a weather phenomenon occurred in lower atmosphere, and has observational limitations because it occurs on the sea. Therefore, goal of this study is to analyze the vertical structures about inflow, development and dispersion of sea fog using the high-resolution weather data with the meteorological sensor-equipped drone. This study observed sea fogs in the west coast of the Korean peninsula from March to October 2021 and investigated one sea fog inflowed into the coast on June 8th 2021. θ_e - q_v diagrams (θ_e: equivalent potential temperature, q_v: water vapor ratio) and vertical wind structures were analyzed. At inflow of sea fog, moist adiabatically stable layer was formed in 0-300 m and prevailing wind was switched from south-southwesterly to west-southwesterly under 120 m. Both changes are favorable for sea fog on the location. θ_e and q_v plummeted in a layer 0-183 m. The inflowed sea fog developed from 183 m to 327 m by mixing with ambient atmosphere on top of sea fog. Also, strong mechanical turbulence near ground drove a vertical mixing under stable layer. At dispersion of sea fog, as θ_e on ground gradually increased, air condition was changed to neutral. Evaporation occurred on both bottom and top in sea fog. These results induced dissipation of sea fog.

• Journal of Microbiology and Biotechnology
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• v.24 no.1
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• pp.70-79
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• 2014

In an attempt to develop a variety of expression vector systems for Corynebacterium glutamicum, six types of promoters, including $P_{tac}$, $P_{sod}$, $P_{sod}$ with a conserved Shine-Dalgarno (SD) sequence from C. glutamicum, $P_{ilvC}$, $P_{ilvC}$ with a conserved SD-1 ($P_{ilvC-M1}$), and $P_{ilvC}$ with a conserved SD-2 ($P_{ilvC-M2}$), were cloned into a modified shuttle vector, pCXM48. According to analysis of promoter strength by quantitative reverse transcription PCR, $P_{sod}$ and $P_{sod-M}$ were superior to tac and ilvC promoters in terms of transcription activity in C. glutamicum. All of the promoters have promoter activities in Escherichia coli, and $P_{sod-M}$ displayed the highest level of transcriptional activity. The protein expression in constructed vectors was evaluated by measuring the fluorescence of green fluorescent protein (GFP) and SDS-PAGE. C. glutamicum harboring plasmids showed GFP fluorescence with an order of activity of $P_{ilvC}$ > $P_{ilvC-M1}$ > $P_{sod}$ > $P_{ilvC-M2}$ > $P_{sod-M}$, whereas all plasmids except pCSP30 with $P_{sod}$ displayed fluorescence activities in E. coli. Of them, the strongest level of GFP was observed in E. coli with $P_{sod-M}$, and this seems to be due to the introduction of the conserved SD sequence in the translational initiation region. These results demonstrate that the expression vectors work well in both C. glutamicum and E. coli for the expression of target proteins. In addition, the vector systems harboring various promoters with different strengths, conserved SD sequences, and multiple cloning sites will provide a comfortable method for cloning and gene expression, and consequently contribute to the metabolic engineering of C. glutamicum.

• Environmental Analysis Health and Toxicology
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• v.22 no.3
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• pp.263-269
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• 2007

Chitosan is a depolymerized and partially deacetylated derivative of chitin. We investigated the cytotoxicity of chitosan in cancer cell lines, such as P388, L1210, HCT-15, SK-HepG-1 and mouse splenocytes as a normal cell by MTT assay. To clarify whether chitosan enhances cytotoxicity of anticancer drugs, we also examined the cytotoxicity of combined treatment with chitosan and anticancer drugs, such as cisplatin, mitomycin C, and 5-fluorouracil in cancer cell lines in vitro. Chitosan ($37.5\;{\mu}g/mL,\;75\;{\mu}g/mL,\;112.5\;{\mu}g/mL,\;and\;150\;{\mu}g/mL$) showed concentration-dependent cytotoxicity in the cancer cell lines. In addition, chitosan showed relatively lower cytotoxicity in normal cells than in the cancer cell lines. Particularly, this trend was significant at high doses of chitosan, i.e. $112.5\;{\mu}g/mL,\;and\;150\;{\mu}g/mL$. Thus, these results suggest that chitosan may selectively induce the growth inhibition in cancer cell lines, compared to normal cells. Furthermore. the co-treatment of chitosan and anticancer drugs exhibited an apparant synergistic cytotoxicity in murine lymphoma cell lines, i.e. P388 and L1210 at $37.5\;{\mu}g/mL$ of chitosan rather than at $75\;{\mu}g/mL$ of chitosan, but such phenomenon could not be observed in solid tumor cell lines, i.e. HCT-15 and SK-HepG-1. However, chitosan did'nt reduced the cytotoxicity against normal mouse splenocytes induced by anticancer drugs. Therefore, it is concluded that the combination of chitosan and anticancer drugs might be useful for the cancer chemotherapy.

• Journal of applied mathematics & informatics
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• v.36 no.5_6
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• pp.567-574
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• 2018

Let $f:f(z)=z+{\sum^{{\infty}}_{n=2}}a_nz^n$ be analytic in the open unit disc E. Then f is said to belong to the class $M_{\alpha}$ of alpha-convex functions, if it satisfies the condition ${\Re}\{(1-{{\alpha})}{\frac{zf^{\prime}(z)}{f(z)}}+{{\alpha}}{\frac{(zf^{\prime}(z))^{\prime})}{f^{\prime}(z)}}\}$ > 0, ($z{\in}E$). In this paper, we introduce and study q-analogue of the class $M_{\alpha}$ by using concepts of Quantum Analysis. It is shown that the functions in this new class $M(q,{\alpha})$ are q-starlike. A problem related to q-Bernardi operator is also investigated.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.9 no.2
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• pp.100-109
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• 1999

This study evaluates the pretreatment for analysis of benzidine metabolites in urine by measuring the recovery rates according to the temperature and periods of storage of the urine. By the solid phas e extraction, the recovery rates of basic hydrolysis are benzidine 67.4 %, monoacetylbenzidine 105.1 %, and diacetylbenzidine 115.8 %, respectively. By the liquid extraction, the recovery rates of back-extraction into 0.1 M perchloric acid are benzidine 105.7%, monoacetylbenzidine 94.2 %, diacetylbenzidine 72.8 %, respectively. The difference of the recovery rates between the back-extraction into 0.1 M HCl and 0.1 M perchloic acid after basic hydrolysis are 101 % and 98.8 %, respectively. When the recovery rates of the urinary s amples of pH 3, pH 7, pH 12 at $25^{\circ}C$ and $-76^{\circ}C$ are compared for four weeks, there are no differences according to the temperature and the periods of storage. The above results show that the solid phase extraction and back-extraction by 0.1 M perchloric acid after basic hydrolys is are suitable for the analysis of benzidine metabolites. There are no difference of the recovery rates of the urinary samples stored at $25^{\circ}C$ and $-76^{\circ}C$ at pH 3, pH 7, pH 12, respectively for 28 days.

• Food Science and Biotechnology
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• v.15 no.4
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• pp.612-616
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• 2006

The protective effect of water extract of ash tree leaves (ALE) against oxidative damages was investigated in paracetamol-induced BALB/c mice. Biochemical analysis of anti-oxidative enzymes, immunoblot analyses of hepatic cytochrome P450 2El (CYP2E1), and the gene expression of tumor necrosis factor (TNF-${\alpha}$) were examined to determine the extract's protective effect and its possible mechanisms. BALB/c mice were divided into three groups: normal, paracetamol-administered, and ALE-pretreated groups. A single dose of paracetamol led to a marked increase in lipid peroxidation as measured by malondialdehyde (MDA). This was associated with a significant reduction in the hepatic antioxidant system, e.g., glutathione (GSH). Paracetamol administration also significantly elevated the expression of CYP2E1, according to immunoblot analysis, and of TNF-${\alpha}$ mRNA in liver. However, ALE pretreatment prior to the administration of paracetamol significantly decreased hepatic MDA levels. ALE restored hepatic glutathione and catalase levels and suppressed the expression of CYP2E1 and TNF-${\alpha}$ observed in inflammatory tissues. Moreover, ALE restored mitochondrial ATP content depleted by the drug administration. These results show that the extract of ash tree leaves protects against paracetamol-induced oxidative damages by blocking oxidative stress and CYP2E1-mediated paracetamol bioactivation.