• Title/Summary/Keyword: Dynamic resolution

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DNA의 구조적, 기능적 특성과 이의 환경, 의료 분야에의 응용

  • Lee, Jeong-Heon;Odom, Teri;Lu, Yi
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2012.05a
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    • pp.55.1-55.1
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    • 2012
  • In the first part of this talk, I will introduce an effort to use gold nanoparticles and UO22+ (uranyl) specific DNAzyme for development of highly sensitive and selective colorimetric uranyl sensors. In addition, I will discuss how DNA aptamers can be delivered by nanoparticles to cancer cell nucleus and released by ultrafast femtosecond pulsed laser for targeted cancer therapy. Finally, I will show how proteins such as streptavidin and myoglobin, or nanoparticles can be precisely aligned on DNA with nanometer resolution via backbone-modified phosphorothioate DNA and bifunctional linkers. These interesting functional and structural properties of DNA can provide new opportunities to develop dynamic DNA structures for potential use as intracellular sensors and drug delivery agents.

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Performance Evaluation of the Dynamic Slot Assignment Protocol using Collision Resolution Algorithm (충돌해결기법을 적용한 동적슬롯할당 프로토콜의 성능 개선)

  • 강경훈;임석구;김수중
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.36S no.5
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    • pp.1-11
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    • 1999
  • 유선망이 ISDN/B-ISDN으로 확장되고, 서비스도 음성에서 데이터, 영상 등의 멀티미디어로 통합 및 발전됨에 따라 무선망에서의 가입자 서비스 요구도 유선망과 대등한 수준으로 확대될 것이다. 이러한 무선 ATM망은 초기 사설망으로부터 서비스가 도입되기 시작하여 마이크로 셀을 기반으로 한 공중망으로 확장되어, 궁극적으로 유무선 통합 transparent 망으로 발전하게 될 것이다. 무선 ATM 망에서는 한정된 무선 자원을 이용하여 다양한 응용 서비스를 효율적으로 제공할 수 있는 다중접속 프로토콜을 필요로 한다. 본고에서는 먼저 현대 MBS에서 연구되고 있는 단일 및 다중 동적슬롯할당 기법을 소개하고 다양한 소스 트래픽에 대한 시뮬레이션을 통해 문제점을 분석하였으며, DSA 프로토콜의 단점을 개선한 두가지 방안의 충돌 해결 알고리즘을 제안하고 동질 및 이질 트래픽에 대한 성능을 비교 검토하였다. 제안된 알고리즘을 이용하여 연결상태에 있는 가상채널의 개수가 증가할수록 시스템 전체의 지연 성능을 현저하게 개선하였다.

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Analysis of Broad-Range DNA Fragments with Yttrium Oxide or Ytterbium Oxide Nanoparticle/Polymer Sieving Matrix Using High-Performance Capillary Electrophoresis

  • Kwon, Hae-Myun;Kim, Yong-Seong
    • Bulletin of the Korean Chemical Society
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    • v.30 no.2
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    • pp.297-301
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    • 2009
  • We have developed the yttrium oxide (YNP) or ytterbium oxide (YbNP) nanoparticle/polymer matrices for the size-dependent separation of DNA ranging from 100 bp to 9,000 bp. High separation efficiency (> $10^6$ plates/m) and the baseline resolution for various DNA standards (100 bp, 500 bp, and 1 kbp DNA ladder) were obtained in 10 min with these matrices. The effects of concentrations of both polyethylene oxide (PEO) and nanoparticles were investigated and the highest performance was obtained at 0.02% PEO with 0.02% YNP or YbNP. Similar sieving power for both YNP and YbNP matrices was observed probably due to the similar sizes of nanoparticles, resulting in the formation of comparable sieving networks for DNA separation. For the reduction of electrosmotic flow, either dynamic or permanent coating of the capillary inner wall was compared and it turned out that PEO was superior to polyvinylpyrrolidone (PVP) or polyacrylamide (PAA) for better separation efficiency.

해난사고 분석을 위한 Full-mission Shiphandling Simulator(FMSS) - 한국해양수산연수원 FMSS를 기준으로 -

  • Lee, Dong-Seop
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2011.06a
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    • pp.71-73
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    • 2011
  • 다기능 선박조종시뮬레이터(Full-mission Shiphandling Simulator)는 항해사, 선장 및 도선사의 자질 향상을 위한 교육뿐만 아니라 항만개발을 위한 사전 검토와 해난사고 발생 시, 원인규명을 위한 분석에도 이용되고 있다. 한국해양수산연수원에서는 이러한 목적을 위하여 2011년 2월 28일 Russia Transas 제품의 선박조종시뮬레이터를 설치 완료 하였다. 이 FMSS는 적어도 360도의 수평시각을 가진 대형 구형화면에 여섯(6) 자유도 운동을 하는 본선 및 타선을 실시간으로 표현하는 photo-realistic high resolution computer graphic visual system과 같은 최신기술을 사용하는 가장 현대화된 최고급 해상용 시뮬레이터로 해난 사고 윈인규명을 위한 분석 연구 목적을 위하여 광범위한 출처로부터 모델시험과 자료의 신뢰할만한 공식적 기록들에 근거한 매우 정확한 수력학적 선박 모델링 소프트웨어로 이루어졌다. 여기서는 이 FMSS의 형태와 복잡성을 상세하게 소개한다.

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Fiber Fabry-Perot Sensor using SLD Light Source (SLD 광원을 이용한 광섬유 패브리페로 센서)

  • Kim, Kwang-Soo;Lee, Byong-Yoon;Lee, Hong-Sik;Rim, Geun-Hie
    • Proceedings of the KIEE Conference
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    • 2000.07c
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    • pp.2186-2188
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    • 2000
  • A fiberoptic sensor using an SLD as a light source has been studied. The sensor system employs an intrinsic fiber Fabry-Perot interferometer as a sensing tip and a fiber Mach-Zehnder interferometer as a processing one. A free loading test for temperature application shows that the fiberoptic sensor has a wide-dynamic range as well as high resolution. Due to the inherent property of the optical fiber itself and the intrinsic Fabry-Perot interferometer. the fiberoptic sensor gives obvious benefits when it is applied to harsh environments to monitor some physical parameters such as temperature, strain, pressure and vibration.

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Small-molecule probes elucidate global enzyme activity in a proteomic context

  • Lee, Jun-Seok;Yoo, Young-Hwa;Yoon, Chang No
    • BMB Reports
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    • v.47 no.3
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    • pp.149-157
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    • 2014
  • The recent dramatic improvements in high-resolution mass spectrometry (MS) have revolutionized the speed and scope of proteomic studies. Conventional MS-based proteomics methodologies allow global protein profiling based on expression levels. Although these techniques are promising, there are numerous biological activities yet to be unveiled, such as the dynamic regulation of enzyme activity. Chemical proteomics is an emerging field that extends these types proteomic profiling. In particular, activity-based protein profiling (ABPP) utilizes small-molecule probes to monitor enzyme activity directly in living intact subjects. In this mini-review, we summarize the unique roles of smallmolecule probes in proteomics studies and highlight some recent examples in which this principle has been applied.

Constructing the mode shapes of a bridge from a passing vehicle: a theoretical study

  • Yang, Y.B.;Li, Y.C.;Chang, K.C.
    • Smart Structures and Systems
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    • v.13 no.5
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    • pp.797-819
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    • 2014
  • This paper presents a theoretical algorithm for constructing the mode shapes of a bridge from the dynamic responses of a test vehicle moving over the bridge. In comparison with those approaches that utilize a limited number of sensors deployed on the bridge, the present approach can offer much more spatial information, as well as higher resolution in mode shapes, since the test vehicle can receive the vibration characteristics of each point during its passage on the bridge. Basically only one or few sensors are required to be installed on the test vehicle. Factors that affect the accuracy of the present approach for constructing the bridge mode shapes are studied, including the vehicle speed, random traffic, and road surface roughness. Through numerical simulations, the present approach is verified to be feasible under the condition of constant and low vehicle speeds.

A Study on the Magnetic Suspension Type Linear Actuator for a Non-contact Surface Actuator (비접촉 평면구동기를 위한 자기 서스펜션방식 직선구동기)

  • Lee, Sang-Heon;Jung, Kwang-Suk;Baek, Yoon-Su
    • Proceedings of the KSME Conference
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    • 2001.06b
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    • pp.735-740
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    • 2001
  • With the development of micro-technology, the demand for micro actuator is increasing. But, it is difficult to achieve high resolution and long travel range simultaneously with the conventional actuators. So, the noncontact surface actuator was proposed. This actuator can realize high dynamic range and the planar motion without complex cross-axis linear slides. This paper describes a magnetically suspended linear actuator for developing a non-contact surface actuator. The operating principle and the structure of the proposed linear actuator are similar to switched reluctance motor, but the proposed linear actuator utilizes normal force and propulsion force simultaneously. With this characteristic, the system can be simpler than other non-contact surface actuator.

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Evaluation of Characteristics of Oxidized Thin LPCVD-$Si_{3}N_{4}$ Film (얇은 열산화-질화막의 특성평가)

  • 구경완;조성길;홍봉식
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.9
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    • pp.29-35
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    • 1992
  • Dielectric thin film of N/O (Si$_{3}N_[4}/SIO_{2}$) for high density stacked dynamic-RAM cell was formed by LPCVD and oxidation(Dry & pyrogenic oxidation methods) of the top Si$_{3}N_[4}$ film. The thickness, structure and composition of this film were measured by ellipsometer, high frequency C-V meter, high resolution TEM, AES, and SIMS. The thickness limit of Si$_{3}N_[4}$ film in making thin N/O structure layer was 7nm. In this experiment, the film with thinner than 7nm was not thick enough as oxygen diffusion barrier, and oxygen punched through the film and interfacial oxidation occurred at the phase boundary between Si$_{3}N_[4}$ and polycrystalline silicon electrode.

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Multi-camera based Images through Feature Points Algorithm for HDR Panorama

  • Yeong, Jung-Ho
    • International journal of advanced smart convergence
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    • v.4 no.2
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    • pp.6-13
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    • 2015
  • With the spread of various kinds of cameras such as digital cameras and DSLR and a growing interest in high-definition and high-resolution images, a method that synthesizes multiple images is being studied among various methods. High Dynamic Range (HDR) images store light exposure with even wider range of number than normal digital images. Therefore, it can store the intensity of light inherent in specific scenes expressed by light sources in real life quite accurately. This study suggests feature points synthesis algorithm to improve the performance of HDR panorama recognition method (algorithm) at recognition and coordination level through classifying the feature points for image recognition using more than one multi frames.