• Journal of Chest Surgery
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• v.3 no.2
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• pp.73-90
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• 1970

Clinical perfusion data on 16 cases of cardiopulmonary bypass using Sigmamotor pump and RyggKyvsgaard Oxygenator which performed at Seoul National University Hospital during the period of Aug. 1968 to Aug. 1970 was analized. AIl cases were hemodiluted and the perfusion was carried out under the normothermic condition. The age of the patients ranged between 6 and 43 years. The b:dy weight varied between 18.3 and 54.0 kg and the body surface area between 0.78 and 1. 59$M^2$. The priming solution was consiste:I with fresh ACD blood. Hartmann solution and Mannitol. The average amount of priming was approximately 2242 ml. The average hemodilution rate was 17%. The flow rate ranged from 1.7L to 3.5L/Min/$M^2$ and averaged 2.4L/Min/$M^2$ or 78mI/Min/kg. The duration of perfusion varied from 22 to 110 min with average of 56.9 minutes. Some hemodynamic responses were observed. The arterial pressure dropped immediately after the initiation of partial perfusion and was more marked after the total perfusion foIlowed by gradual increase to the safety level. The central venous pressure reflected the reduced blood volume especially in the cases of prolonged perfusion which lasted over 60 min. In most of the cases, red blood cell count decreased and white blood ceIl count increased after the perfusion. Hemoglobin level was decreased, averaging of 12.5mg%, Hct 3.3% and platelets count of 18% postoperatively. Plasma hemoglobin increased mildly, from pre-perfusion average value of 4. 06mg% to postperfusion value of 22.5mg%. Serum potassium was 4.4mEq/L pre-operatively and was decreased to 3.7mEq/L postoperatively. Five cases showed definite hypopotassemia immediately after the operation. Sodium and chloride decreased mildly. These electrolyte changes are thought to be related with hemodilution. diuretics and reduced blood volume during and after the perfusion. Arterial blood pH value revealed minimal to moderate elevation from preperfusion average value of 7.376 to 7.461 during perfusion and then 7.365 after perfusion. The pC02 and hicarbonate showed minimal to moderately lowered values. The total CO2 was decreased. Buffer base decreased during perfusion (Av. 42.6mEq/L) and further decreased after the perfusion (Av. 40.8mEq/L). These arterial blood acid base changes suggested that the metabolic acidosis was accompanied by respiratory alkalosis during and immediately after the perfusion. Authors belived that the acidosis could more effectively be corrected with the more additional dose of bicarbonate than we used by this study. The chest tune drainage during the first 24 hours following operation was 1158 ml in average. One case (Case No. 15) showd definite bleeding tendency and it was believed that the cause might be due to the defect of heparin and protamine titration. The average urinary out put during 24 hours post-perfusion was 1291ml. One case (Case No. ]) showed definite post perfusion oliguria. As conclusion hemodilution using fresh ACD blood. Hartmann and Mannitol solution added with Bivon and high flow rate unler normothermia. was thought to amelioratc the severity of mctabolic acidosis during and after perfusion with relatively satisfactory effect on the diuresis and bleeding tendency.

• Resources Recycling
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• v.26 no.4
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• pp.26-33
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• 2017

The behavior on the solvent extraction of heavy rare earths (HRE) by using PC88A was confirmed to demonstrate the possibility of recovery on the HRE from industrial wastewater, which consist of low concentration rare earth. We verified the extraction behavior of the HRE through a change of equilibrium pH, extractant concentration and A/O ratio, and also confirmed the stripping behavior depending on the type of mineral acids. At equilibrium pH 1.0, extraction of rare earth (RE) was completed from 95% to 100%. In all extraction conditions, it tend to be extracted in order of high atomic number. When A/O ratio was 10/1, Yb and Tm were concentrated at the maximum and increased 6-fold and 3-fold compared to initial concentration, respectively. To confirm the stripping behavior of the RE, three mineral acids were applied to the organic phase and consequently rate of stripping was increased in order of $HNO_3$, $H_2SO_4$ and HCl.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.8
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• pp.2818-2826
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• 2010

This research was conducted to develop a model appropriate for the measurement of information quality of UCC service site. The evaluation factors that reflect more improvement of the information utilization capability were verified. Enhancement of information utilization capability can control greater amount of information among the users and site companies, and among users. Therefore, Wikipedia, for example, provides a Web 2.0 based information quality that is more advanced than Web 1.0 by allowing effective control of information among the users. This type of information quality presents 'information reliability' and 'information stability' as evaluation factors added to the factors such as 'information sufficiency' and 'information usability.' Information reliability and information stability are essential factors that need to conduct an evaluation in the Web 2.0 environment that can distribute greater number of information in the environment where all the users serve as participants. Moreover, 'interesting information' and 'originality of information' suggests that information itself should include the attributes that can attract the attention of users, due to the nature of the Attention Economics, which points out one of the Web 2.0 phenomenon that the number of information consumers is smaller than that of information suppliers.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.174-180
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• 2006

We examine the effect of Geiji-Bokryung-Hwan(GBH) on erectile function in a rat model of hypercholesterolemic erectile dysfunction. GBH, a drug preparation consisting of five herbs of Cinnamomi Ramulus (Geiji), Poria Cocos (Bokryun), Mountan Cortex Radicis (Mokdanpi), Paeoniae Radix (Jakyak), and Persicae Semen (Doin) is a traditional Korean herbal medicine that is widely used in the treatment of atherosclerosis-related disorders. In this study, 3-month-old Sprague-Dawley rats were used. The 6 rats control animals were fed a normal diet and the other 18 rats were fed 1% cholesterol diet for 3 months. After 1 months, GBH was added to the drinking water of the treatment group of 12 rats but not the cholesterol only group of 6 rats. Of the 12 rats 6 received 30 mg/kg per day (group 1) and 6 received 60 mg/kg per day (group 2) of GBH. At 3 months erectile function was evaluated with cavernous nerve electrostimulation in all animals. Penile tissues were collected for electron microscopy, and to perform Western blot for endothelial nitric oxide synthase (eNOS), neuronal nitric oxide synthase (nNOS), basic fibroblast growth factor (bFGF) and caveolin-1. Systemic arterial pressure was not significantly different between the animals that were fed the 1% cholesterol diet and the controls. Conversely erectile function was not impaired in the herbal medicine treated rats. Electron microscopy showed many caveolae with fingerlike processes in the cavernous smooth muscle and endothelial cell membranes in control and treated rats but not in the cholesterol only group of rats. Western blot showed differences among groups in protein expression for eNOS, nNOS, caveolin-1 and bFGF protein expression in penile tissue. Increased eNOS and nNOS protein expressions dy high cholesterol diet were significantly decreased in group 1 and group 2. Interestingly, caveolin-1 and bFGF protein expression was significantly higher in groups 1 and 2 than in the cholesterol only and control groups.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.22 no.4
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• pp.258-271
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• 2010

In order to figure out hydrodynamic and water quality changes after completion of dike construction of the Saemangeum, which behaves as a semi-enclosed estuarine lake, numerical simulations based on fine grid structure by using EFDC were intensively carried out. In this study some limitations of precedent study has been improved and gate operation were considered. Also 3 phases such as air-water-sediment interaction modeling was considered. It is clear that inner mixing of the Saemangeum is dominated by Mankyeong and Dongjin riverine discharges rather than the gate opening influence through the Lagrangian particle tracking simulations. Vertical DO structure after the dike completion shows steep gradient especially at Dongjin river estuary due to lessen of outer sea water exchange. Increasing SOD at stagnantly changed man-made reservoir might cause oxygen deficiency and accelerating degradation of water quality. According to TSI evaluation test representing eutrophication status, it shows high possibility of eutrophication along Mankyeong waterway in spite of dike completion, while the index is getting high after final closing along Dongjin waterway. Numerical tests with gate operations show significant differences in water quality. Thus it should be noted that proper gate operation plays a major role in preserving target water quality and management for inner development plan.

• Journal of the Korean Geographical Society
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• v.29 no.3
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• pp.340-359
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• 1994

This study intends to describe the characteristics of the transformation of the rural society by tracing the changing social and economic processes of traditional clan villiage (Yeolmi-ri, Silchon-myeon, Kwangju-gun, Kyunggi-province) in the suburbs of Seoul Metropolitan Area. Rural society has experienced serious change of the social structure by the ever expanding urbanization and industrialization since 1960's. The suburbs of Seoul Metropolitan Area is the representative case area of such transformation. This study analyzed various chracteristics of population structure of a villiage, the processes of residential movement and the occupational shift of each household of the villiage in terms of household's life-history collected by interviewing with each household. And the whole households of a villiage is divided by two groups of the native clan group and the non-dan in-migrant group. The results of this study are summarized as follows. 1) This villiage is located within a lineal distance of 40km and a time distance of about 30 to 40 minutes, adjoined dy the Joongbu(중부) national highway, the Kyungchoong (경충) industrial road, the local road between Yangpyuna(양평) and Gonjiam(곤지암) and having a advantageous iocational linkage to Seoul capital city. 2) It is a typical traditional dan villiae constituted of dan family Gu(구) one of whose ancestors had appointed to the prime minister of Chosun Dynasty, and until 1979, 56 out of 60 families of the villiage households were clan families. 3) Since 1979, as the villiage invaded by the out-movement of the small scale manufacturing industries from Seoul capital city, labours moved in this vallige from outside and increased villiage size up to 203 households in 1993, consequently the constitutional proportion between the native clan group and the non-clan in-migrant group was reversed up to 28% vs 72% deepening the sociological heterogeneity. 4) Because of the small scale of industries in this villiage and the vicinity with the city of Seoul, the population turnover of this villiage is very high. The turnover frequency is firstly high within same administrative district of gun(군) level and secondly high between this villiage and the city of Seoul. Thus short-distance movement is identified. 5) There is a close correlation between the residential movement and the occupational shift. The most numbers of non-farm native group have the experiences of migration while the members of native farming group don't shift both the job and the place of residence. The inmigrant group had several migration experiences but few occupational shifts. Thus occupatioanl shift is high for the native group while residential shift is high for the in-migrant group. It is concluded that the change proceeded in Metropolitan suburbs was not directed to form the traditional rural village as 'gesund Gebiet' with respect to the ballance among the economic, cultural and environmental adequency.

• Journal of the Korean Magnetics Society
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• v.22 no.3
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• pp.109-115
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• 2012

NeFeB anisotropy bonded magnet has proposed a new paradigm of weight reduction of small motors by replacing the conventional ferrite permanent magnets with its high magnetic property of 25 MGOe during last five years. It has also advanced by leaps and bounds in the field of motor industry for automobiles and electric power tools. And it has led a new innovation of fifty percent weight lightening compared to its current motors by correctly focusing on fuel performance improvement through weight lightening that automobile industry chased. There was, however, another price skyrocketing in 2011 after China had announced its export regulation in rare earth materials in July, 2010. And this price change has an extensive impact on the industries that consume rare earth magnets. This environmental change has caused technical challenge to improve the performance by using least amount of rare earth elements in NdFeB anisotropy bonded magnets, and led to make a new technical approach to a new applied field. In this article, we will show how each nation deals with this industrial issue, and introduce development trend and application of anisotropic NdFeB bonded magnets, so-called MAGFINE made by Aichi Steel Corp.

• Industry Promotion Research
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• v.8 no.3
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• pp.19-35
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• 2023

Recently, the government has emphasized the importance of establishing an innovation system for SMEs as part of an innovative growth strategy for national economic development. SMEs in Korea are experiencing many difficulties due to the loss of industrial competitiveness due to the powerful wave of the 4th industrial revolution along with the pandemic of COVID-19 that started in 2020. In relation to environmental changes, it is emerging as an important issue for SMEs to pursue open innovation for survival and growth, as well as to possess excellent technological innovation capabilities. In accordance with the need for such research, this study analyzed the factors that affect business performance or technological performance of small and medium-sized manufacturers, and identified the relationship between these influencing factors and corporate performance. The results of this study suggest that it is important for SMEs to effectively utilize R&D services and technology innovation capabilities and resources possessed by SMEs to secure a competitive advantage. The results of this stu dy are considered to be able to provide basic data and information necessary for SMEs to secu re a competitive edge and enhance industrial competitiveness through government support systems and open innovation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.352-357
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• 2006

This experimental study was designed to investigate the effects of Acanthopanax sessiliflorus $S_{EEM}$ leaves, stems, roots (ACL, ACS, ACR) on the change of weight and the serum total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, free fatty acid, total lipid and phospholipid level in obese mice induced Dy high fat diet. Experimental groups were as follows ; Normal group was fed with normal diet and administered with distilled water during 7 weeks, Control group was fed with high fat diet and administered with distilled water during 7 weeks, Sample A group was fed with high fat diet and administered with ACL of 500 mg/kg/mouse/day during 7 weeks, Sample B group was fed with high fat diet and administered with ACS of 500 mg/kg/mouse/day during 7 weeks, Sample C group was fed with high fat diet and administered with ACR of 500 mg/kg/mouse/day during 7 weeks. The results were as follows ; 1. Sample A group, Sample B group and Sample C group were significantly decreased the serum total lipid level in comparison with Control group. 2. Sample A group was decreased the body weight (4 weeks, 7 weeks), the serum total cholesterol level, the serum LDL-cholesterol level, the serum triglyceride level, the serum free fatty acid and phospholipid level but increased the serum HDL-cholesterol level in comparison with Control group. 3. Sample B group was increased the serum HDL-cholesterol level but decreased the body weight (4weeks), the serum total cholesterol level, the serum free fatty acid and triglyceride level in comparison with Control group. 4. Sample B group was significantly decreased the body weight (7 weeks), the serum LDL-cholesterol and phospholipid level in comparison with Control group. 5. Sample C group was increased the serum HDL-cholesterol level but decreased the body weight (4 weeks) and the serum free fatty acid level in comparison with Control group. 6. Sample C group was significantly decreased the body weight (7 weeks), the serum total cholesterol level, the serum LDL-cholesterol and triglyceride level in comparison with Control group. According to above results, I suggest ACR is able to be used for the obesity.

• Journal of Korean Physical Therapy Science
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• v.30 no.1
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• pp.10-22
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• 2023

Background: The purpose of this study was to investigate the effect of brain education-based exercise and KPEM manual therapy integrated program on the sleep and quality of life of cancer patients. Design: Seventy subjects who were diagnosed with cancer and were undergoing treatment volunteered to participate in this study. All subjects used a nonequivalent control group pretest-posttest design for either the experimental group or the control group. In the final analysis, there were 25 subjects in the experimental group and 18 subjects in the control group. Methods: For 12 weeks, the experimental group performed brain education-based exercise (20 minutes) and KPEM manual therapy (50 minutes), and the control group performed basic physical therapy and autonomous exercise. For evaluation, the Korean version of the Pittsburgh Sleep Quality Index (PSQI-K) and the quality of life index were measured after intervention using the European Organization for Research and Treatment of Cancer (EORTC-3.0Ver). Effect between groups, time effect over time, and group^*time interaction were analyzed through a pre-test before and after the 12-week intervention period, and repeated measure ANOVA after 12 weeks of the integrated program intervention. All statistical significance levels were set at α=.05. Results: The PSQI in the time effect (p=.001) and the group^*time interaction (p<.001) were statistically significant. In terms of EORTC, QL2 and PF2 were significant in time effect (p=.024; p=.021) and group^*time interaction (p=.007; p=.021), whereas in RF2, significance was only found in group^*time interaction (p=.028). In symptom indicators, time effect was the only significant factor in FA, SL, AP, and CO, respectively (p=.002; p=.028; p=.041; p =.005) and in DY, there were significant differences in the time effect (p=.016) and group^*time interaction (p=.002). Conclusion: The brain education-based exercise and KPEM manual therapy integrated program effectively improves the sleep and quality of life of cancer patients. It is considered that this exercise and therapy can be actively used as a psychological, emotional, and physically complementary physical therapy intervention to improve the quality of life of cancer patients.