The purpose of this study was to evaluate the effects of the chincap therapy on the craniofacial structure in persons with skeletal Class III malocclusion. The patients selected for this study were treated with extra-oral chincap therapy only. Both control and treatment samples were obtained from Seoul National University Hospital where these longitudinal data were gathered. 55 treated patients and 14 control patients were studied. The mean ages at the 1st evaluation was 8 years 3 months in the treatment sample and 9 years 4 months in the control sample. The duration of chincap therapy was variable but averaged 2 years of treatment. Post-treatment observation procedeeded for 1 year 2 months. Active treatment and post treatment effects were evaluated. The results were as follows: 1. Neither significant restraint nor acceleration of growth was found in the cranial base and maxilla during treatment. 2. A distal rotation of the mandibular complex was seen. 3. Some amount of restraint of growth was found in mandibular body length, ramus height, mandibular length during treatment. 4. The genial angle was reduced. 5. After removal of the chin-cap, forward displacement of the mandible took place.
Lee, Brian Seong-Hwa;Seo, Kwang-Suk;Shin, Teo-Jeon;Kim, Hyun-Jeong;Han, Hyo-Jo;Chang, Ju-Hea
Journal of The Korean Dental Society of Anesthesiology
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v.11
no.2
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pp.125-132
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2011
Background: Adult patients with intellectual disabilities often strongly resist the anesthetic administration for dental procedures. This study aimed to evaluate the effect of midazolam premedication in improving the cooperation level of patients who are likely to be combative and irritated during general anesthesia (GA) induction. Methods: The patients who had received dental treatment under ambulatory GA for more than two times were included. And we selected 13 patients total that needed physical restraint or ketamine IM prior to induction at the first GA, and were prescribed midazolam tablet (7.5-15 mg) at the following GA. We reviewed pre-anesthetic records and anesthesia records, and evaluated cooperative levels of patients (4 levels scale) during anesthesia induction and recovery time retrospectively. Results: All 13 patients (Male 11, Female 2) had severe mental disabilities. The average age of the patients was 24 ${\pm}$ 7 (13-37) years and their average weight was 58 ${\pm}$ 16 (34-91) kg. At the first GA, 10 patients needed physical restraint prior to induction (level 3). And 3 patients were so poorly cooperative that the induction procedure was performed after intramuscular injection of ketamine (level 4). But after the midazolam intake, 7 patients were willing to receive the anesthetic induction (level 1, 2), and 6 patient needed physical restraint (P < 0.05). There were no statistical differences in the duration of general anesthesia and postoperative recovery. Conclusions: Oral intake of midazolam was effective in improvement of cooperation without any complications.
Journal of Physiology & Pathology in Korean Medicine
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v.34
no.2
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pp.88-96
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2020
Stauntonia hexaphylla (SH) and Vaccinium bracteatum (VB) are herbal extracts widely used in food and traditional herbal medicine, and have the ability to perform a wide range of biological activities. We aimed to investigate the effects of the SH and VB combination (SHVB) on mice models of chronic restraint stress (CRS) and pentobarbital-induced sleeping behaviors to elucidate its possible mechanisms of action. CRS-exposed mice treated with SHVB showed significantly decreased immobility time, increased swimming and climbing times in the forced swim test (FST), and increased locomotor activity in the open field test (OFT). SHVB decreased serum CORT levels, but enhanced brain monoamine neurotransmitters. SHVB significantly decreased the sleep latency and increased total sleep duration in pentobarbital-induced sleeping behavior in mice. SHVB showed inhibitory effect on 5-HT2A receptor-mediated ERK1/2 phosphorylation. These results suggest that SHVB has antidepressant and hypnotic effects by regulating the 5-HT2A receptor.
This report evaluated the convenience and accessibility of a penile translocation surgery in the lateral recumbency of a calf using a tilt-up mobile compared with that of dorsal recumbency on the ground of a barn. One nine-month-old F-1 (Korean native sire x Holstein dam) calf was sedated with xylazine (0.03 mg/kg, IV) and restrained in the right lateral recumbency position on a tilt-up restraint mobile (90 cm high), whereas the other nine-month-old Korean native calf was administered xylazine (0.3 mg/kg, IV) and restrained in dorsal recumbency position on the ground of a barn, with assistance by one person. For the two calves, lidocaine was administered subcutaneously from the preputial orifice to the S-shaped penis. The preputial orifice was incised, and the preputial sheath and penis were separated bluntly, then laterally translocated to the site toward the left flank at a $40^{\circ}$ angle. Anti-inflammatory drug (ketoprofen) and antibiotics (penicillin) were administered following the surgery. The duration of surgery was 30 min shorter in the calf that received the surgery in lateral recumbency using the tilt-up mobile with operator's standing posture (60 min) than the one that underwent surgery in dorsal recumbency on the ground with operator's bending posture (90 min). One week after the surgery, the operation area, including the translocated preputial orifice, was healed without complications in both cases. The results detailed in this report demonstrate that penile translocation surgery in the lateral recumbency position using a tilt-up mobile might be used conveniently in calves due to the convenience of restraint, reduced surgery time, and reduced physical inconvenience for the surgeon.
Red ginseng (RG, the extract of Panax ginseng Meyer) has various biological and psychological activities and may also alleviate fatigue-related disorders. The present study was undertaken to evaluate what kind of fatigue red ginseng alleviate. Animals were orally administered with 50, 100, 200, 400 mg/kg of RG for 7 days. Before experiments were performed. Physiological stress (swimming, rotarod, and wire test) are behavioral parameters used to represent physical fatigue. Restraint stress and electric field test to a certain degree, induce psychological fatigue in animals. Plasma concentration of lactate and corticosterone (CORT) were also measured after these behavioral assays. RG supplementation (100 mg/kg) increased movement duration and rearing frequency of restrainted mice in comparison with control. 100 and 200 mg/kg of RG increased swimming time in cold water ($8{\pm}4^{\circ}C$) while at 100 mg/kg, RG increased electric field crossing over frequencies. 50, 100 and 200 mg/kg RG prolonged running time on the rotarod and at 100 mg/kg, it increased balancing time on the wire. RG at those doses also reduced falling frequencies. RG supplementation decreased plasma CORT levels, which was increased by stress. Lactate levels were not significantly altered. These results suggest that RG supplementation can alleviate more the damages induced by psychological than physical fatigue.
International Journal of Aerospace System Engineering
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v.9
no.2
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pp.1-9
/
2022
The NEA release mechanism is used to provide restraint and release functions with low shock for critical deployment operations on solar arrays after launch. The GK3 solar array consists of 2 wings and 6 hold down points per panel. The NEA SSD9103S1 is a part of the GK3 solar array hold-down and release mechanism. Each NEA unit is equipped with two Z-diodes which provide power to a NEA unit connected in series after actuation of the fuse wire. This paper presents the hot firing test results of a quadrature NEA SSD9103S1 configuration. One output powers a maximum of 4 NEA SSD9103S1 units simultaneously. The necessary actuation pulse duration has been determined to meet margin requirement for thermal energy of minimum 4. Actuation thermal energy difference is about 6.6% between each half of two fired serial NEAs. Thermal energy margin at worst case is minimum 5.9 in case of an actuation pulse duration of 500 ms. Two series Zener impedance depend on current applied has been characterized by an additional actuation after all fuse wires are open circuit. Total number of actuation commands to the GK3 NEA unit reduce drastically from 24 in case of single NEA configuration down to 8 in case of parallel and quadrature NEA configurations. It can be accommodated by the existing HP2U Pyro design without any impact.
This study aimed at comprehending the meaning of sexual life for aged people, their strength of sexual desire and causes of change in their sexual life. It was another purpose to understand the extent of aged people's acknowledging the necessity of sexual consultation. This study adopted descriptive method using open-ended questionaires. The data for study was collected from 26 people over 65 years who reside in communities. It was gathered from April to June of 1998 through interview. The interviewee includes 16 males, 9 females and their average age was 73.3. 19 people among them have spouses. The conclusion of this study can be summarized as follows. 1) Attitude to sexual life: The meaning of sexual life for aged people is categorized as 'sense of duty', 'feeling of intimacy', 'basic desire', 'decrease of meaning' and 'meaningless'. 2) Sexual desire: Sexual desire of aged people is categorized as 'extinction', 'decrease', 'continuation' and 'restraint'. Restraint of sexual desire is due to social convention or the difficulty in fulfilling desire. 3) Causes of troubles in sexual life Causes which lead to troubles in sexual life of aged people can be categorized as 'physical', 'psychological' and 'social'. 'Physical' elements include 'incompetence of erection', 'decrease in duration of erection', 'increase in time needed to re-erection', 'declining of physical strength', 'decrease in vagina secretion' and 'worsening of health'. Among 'psychological' elements 'decrease of self-confidence', 'diminished concern of female aged people' are. 'Social elements' are 'absence of sexual parter', 'circumstances of living' and 'recognition of neighbor'. 4) Response to change of sexual life The reaction of aged people to change of sexual activities is classified as 'positive' and 'negative'. 5) Attitude to the consultation of sexual life of aged people The attitude to the consultation of sexual life in old age is classified as 'negative', 'doubtful' and 'positive'. This study explored the meaning which aged people in community attach to sexual life, the extent of their sexual desire, the causes of troubles in their sexual life, their emotional response to changes in sexual life, their recognition of necessity in sexual consultation. Considering the frequency of the statement, most of aged people who were interviewed thought much of sexual life and put emphasis on it. Those who said that sexual life has decreased meaning or is not important to them are few, Though aged people still maintain sexual desire, most of them have some trouble in sexual life. These trouble changes the sexual life, and results in negative feeling such as depression, renunciation and difficulty in relations. So they acknowledged that sexual consultation is necessary to them.
Journal of the Korea institute for structural maintenance and inspection
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v.19
no.1
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pp.120-127
/
2015
The purpose of this study is to improve the fire prevention performance using the fire venetian blind louver subjected to burning by fire flame. The investigation is based on testing 2 full scale specimens, which is $3m{\times}3m$ module, $850mm{\times}1,500mm$ open, and $900mm{\times}900mm{\times}175mm$ venetian blind louver. Two louver thickness (1.5 and 2.0mm) were adopted. The specimens were exposed to fire flame temperature levels of ISO834 at the lower surface of the fire venetian blind louver specimens with exposure duration of one hour in Korea Institute of Construction Technology (KICT). It was found from the test results that the values of distributed temperature, decreased for all specimens for protecting to fire flame by venetian blind louver. The results of tests were a good fire prevention performance between in initial to 6 mins. At 60 minutes around ISO 834 fire loading, the percentages of distributed temperature in 500mm and 800mm height ranged between 11 and 10% respectively, regardless of louver thickness. This study, therefore, will improve the fire venetian blind louver for fire protection and prevention performance.
To evaluate the effects of Zoletil (tiletamine- zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoletil was administered by intramuscular injection. Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration and at 1, 10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, $PCO_2$, $PO_2$ after Zoletil administration rut temperature, respiraticn rate, pH were significant difference compared with these of Mere administration. The induction time was $2.5{\pm}1.0min$ and maintenance time was $86{\pm}23.2min$. It was considered that Zoletil could be usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.
The object of International License Contract is technology. Technology is means to produce visible goods, which are human's intellectual creations such as Intellectual Property Right - patent, design, trademark- and Know-how. Unlike visible goods which decrease as being used, these technologies are possible to be produced expansively and develop additionally. Therefore, the way to make a contract of goods is a sales contract which transfers ownership while technology follows license contract which gives approval of use for a certain period. International license contract means that licensor has right to possess, allows licensee to use licensed technology for a fixed period and takes royalty. So there are various matters such as selection of the duration of a contract, confirmation of technology range, competition limitation, technique guidance and support, calculation of royalty, withholding tax between parties. This study examines licensor's grant of license and competition limitation. Intellectual property rights fundamentally give exclusive rights to the creator so the licensor use or dispose of his or her intellectual property rights at will. Technology transfer is possible through license contract because of this right. But licensor must exercise his or her intellectual property rights within a reasonable limit. It means, when licensor makes an unreasonable demand abusing his or her position, it is regarded as competition limitation clause and the deal itself may become null. Therefore, restraint on competition needs to be examined in detail as it influences on contract validity. Each country has their own competition laws for establishing a fair market order and inspection guide and guideline for judging whether there is any unfair act related to intellectual property rights. Judgment on intellectual property rights is subject the technology-introduced country's domestic laws and thus, contracting parties each need to precede opposite nation's domestic laws system.
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