• Title/Summary/Keyword: Duration Curve

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Reevaluation of $^{99m}Tc$-HSA Erection Penography in the Impotence Patients (발기부전의 선별검사로서 파파베린유도 음경발기 촬영술의 재조명)

  • Kim, Deuk-Gyu;Park, Chung-Ha;Park, Hee-Seung;Chung, Kyung-Woo;Kim, Jong-Sung
    • The Korean Journal of Nuclear Medicine
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    • v.28 no.3
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    • pp.371-376
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    • 1994
  • To reevaluate the clinical usefulness of erection penography for diffential diagnosis of impotence, we reviewed retrospectively the data of penography in 56 patients who were diagnosed as impotence by various diagnostic workup. Twelve normal males were studied as control group. Papaverine HCl 30mg was injected into the corpus cavernosum and simultaneously $^{99m}Tc$-HSA 20mCi was injected via an antecubital vein. After injection radioactivities in the penile area were detected for 30 minutes by gamma camera and time activity curve was displayed. We defined that transit time(TT) is the time to reach peak activity and erection persistent time(EPT) is the duration of time to maintain peak activity and venous index(VI) is the ratio of radioactivity($R_{30}/R_{max}$). The results were as follows. The TT of arteriogenic group($10.7{\pm}2.8min$) was significantly increased compared with those of control and venogenic groups(P<0.05, respectively). The EPT of venogenic group ($6.2{\pm}6.8min$) is significantly decreased compared with those of control and arteriogenic groups(P<0.05, respectively). The TT of psychogenic($15.2{\pm}5.5min$) is significantly increased compared with those of control and arteriogenic groups(P<0.05, respectively). In conclusion erection penography was very useful for the diagnosis of vascular and psychogenic impotence and for differentiation between arteriogenic and venogenic but it could not differentiate mixed type or neurogenic from vascular or psychogenic.

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Flow Duration Curve Analysis for Nak-dong River Basin TMDL Using TANK Model (TANK 모형을 이용한 오염총량관리 목적 낙동강 유황 분석)

  • Kim, Sang-Dan;Kim, Jae-Chul;Kang, Doo-Kee;Shin, Hyun-Suk
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.1048-1052
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    • 2007
  • 그동안의 하천 유량자료는 주로 홍수방어를 목적으로 구축되어진 관계로 대부분 홍수기에만 의미있는 자료를 갖추고 있으며, 환경관리에 필요한 저갈수기 유량자료는 그 신뢰도가 매우 떨어지고 있다. 다행히 지난 2004년 하반기부터 4대강 물환경 연구소에서 직접 오염총량관리 단위유역 말단부에서 8일 간격으로 유량과 수질을 동시에 측정하기 시작하였고, 사업의 결과 건기 우기의 구별 없이 연중 일정한 간격으로 하천유황 및 수질의 변동여부를 확인하는 것이 가능하게 되었으나, 각 단위유역별 유황곡선을 작성할 목적으로 8일 간격 유량자료를 사용할 수 없다는 단점이 있다. 즉, 현재 관측 중인 8일 간격 유량자료만으로는 동시 관측이 진행 중인 수질항목과 유량 사이의 상관관계 정도를 파악한다거나, 어떤 방법으로든 수문모형을 구축한 후 이를 부분적으로 검정할 때 참고자료로 사용하는 정도로 그 용도가 한정될 수밖에 없는 실정이다. 이에 본 연구에서는 낙동강 오염총량관리 41개 단위유역 전체를 대상으로 관측된 8일 간격 유량자료를 이용하여 이를 1일 간격 유량자료로 확장을 시도하였다. 이를 위하여 기존의 TANK 모형에 하도추적기능을 추가한 보다 진보된 TANK 모형을 구성하였다. 낙동강 단위유역별 취수량과 방류량을 바탕으로 한 물수지 자료 또한 구비하여 모형에 고려되도록 하였다. 모형의 매개변수 추정을 위하여 국립환경과학원 낙동강물환경연구소에서 8일 간격으로 관측한 유량자료가 이용되었다. 분석결과 모의된 일유량이 실제 유량을 비교적 잘 재현하는 것으로 나타남에 따라 8일간격 유량관측자료의 일유량으로의 확장 가능성을 확인할 수 있었다. 구축된 모형은 적용에 앞서 10년 평균 저수량을 기준으로 1차 오염총량관리 기준유량과의 비교를 시도하였으며, 상류 댐 방류의 영향 및 물수지의 영향을 배제한 상태의 자연유량을 산정하여 이를 현재 유황과의 비교를 수행하였다. 현재유량과의 비교 결과 다목적 댐의 방류효과로 인한 유량 증가효과 및 대규모의 취수로 인한 유량 감소효과가 뚜렷하게 나타남을 알 수 있었다. 산정된 자연유량을 통하여 비유량을 산정한 결과 $5,000km^2$이하인 유역 면적의 경우 비유량 $0.0048m^3/s/km$를, $5,000km^2$이상인 경우에는 비유량 $0.0043m^3/s/km$를 적용하는 것이 바람직할 것으로 분석되었다. 여기에 유역의 물이용 및 상류의 댐 방류 효과가 고려되면 실제 유역의 저수량을 개략적으로 산정할 수 있을 것으로 기대된다.

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Prognosis in the Patients with Prolonged Extracorporeal Membrane Oxygenation

  • Kim, Tae-Hun;Lim, Cheong;Park, Il;Kim, Dong-Jin;Jung, Yo-Chun;Park, Kay-Hyun
    • Journal of Chest Surgery
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    • v.45 no.4
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    • pp.236-241
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    • 2012
  • Background: Prolonged usage of extracorporeal membrane oxygenation (ECMO) may induce multi-organ failure. This study is aimed to evaluate prognostic factors in the patients with ECMO. Also, the prognosis of ECMO with Kidney Injury Network Scoring system is studied. Materials and Methods: From May 2005 to July 2011, 172 cases of ECMO were performed. The cases of perioperative use of ECMO were excluded. Renal failure patient and younger than 15 years old one were also excluded. As a result, 26 cases were enrolled in this study. Male patients were 15 (57.7%), and mean age was $56.57{\pm}17.03$ years old. Demographic data, ECMO parameters, weaning from ECMO, and application of continuous renal replacement therapy are collected and Acute Kidney Injury Network (AKIN) scores were evaluated just before ECMO and day 1, day 2 during application of ECMO. Results: Venoarterial ECMO was applied in 22 cases (84.6%). The reasons for applications of ECMO were cardiac origin in 21 (80.8%), acute respiratory distress syndrome in 4, and septic shock in 1 case. Successful weaning from ECMO was achieved in 15 cases (57.7%), and survival discharge rate was 9 cases (34.6%). Mean duration of application of ECMO was $111.39{\pm}54.06$ hours. In univariate analysis, myocarditis was independent risk factors on weaning failure. Using the receiver operating characteristic curve, level of hemoglobin on 24 hours after ECMO, and base excess on 48 hours after ECMO were showed more than 0.7. AKIN score was not matched the prognosis of the patients with ECMO. Conclusion: In our study, the prognosis of the patients with myocarditis was poor. Hemoglobin level at first 24 hours, and degree of acidosis at 48 hours were useful methods in relating with prognosis of ECMO. AKIN scoring system was not related with the prognosis of the patients. Further study for prognosis and organ injury during application ECMO may be needed.

Effects of Medroxy Progesterone Acetate (MPA) Treatment on Growth of Velvet Antler in Sika Deer and Elk Deer (MPA 투여가 사슴뿔의 성장에 미치는 영향)

  • Kim, S.W.;Choi, S.H.;Sang, B.D.;Kim, Y.K.;Yoo, C.H.;Seo, K.W.
    • Journal of Animal Science and Technology
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    • v.47 no.5
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    • pp.905-912
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    • 2005
  • The study was conducted to determine the effects of hormone injection on casting day of antler, velvet antler yield, and blood hormone concentration in elk deer and Sika deer. The study revealed that the casting day of Elk and Sika deer at medroxy progesterone acetate(MPA) injection averaged 21 days after MPA injection, which was earlier 38 and 24 days, respectively, compared control(P<0.01). The regrowth of antler in both Sika deer and Elk occurred in the MPA injection and the duration of antler growth was 2 times longer than control. The total yield of velvet antler of Elk in the control and MPA injection was 7.31 and 10.11kg and the that of sika deer was 1.00 and 1.41kg, respectively. Blood testosterone concentration of Sika deer and Elk was less than 4.0ng/ml for both at the casting and during the antler growing. Blood IGF-1 concentrations of Sika deer and Elk during the antler growing tended to increase with the same as growth curve of antler.

The Profitability Analysis of BESS Installation with PV Generation under RPS (RPS 제도 하에서의 태양광발전 연계형 배터리시스템 수익분석 방법에 관한 연구)

  • Kim, Chang-Soo;Yoo, Tae-Hyun;Rhee, Chang-Ho
    • Journal of Energy Engineering
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    • v.26 no.4
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    • pp.107-117
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    • 2017
  • Since South Korea started to apply Renewable Portfolio Standard (RPS) in 2012, there have been huge investment for deploying renewable technologies. Recently, the government determined to incentivize battery energy storage system(BESS) with renewable generations in order to induce the improvement of dispatching capability. In this paper, the annual pattern of PV generation based on actual generation data in South Korea is analyzed and the duration curve of capacity factor is proposed in order to provide the simplified analyzing methodology of present support policy for additional BESS installation for decision maker who is responsible for supply and demand planning. With suggested methodology, the range of appropriate BESS size with respect to the variation of system marginal price(SMP) and renewable energy certificate(REC) price can be derived briefly, and decision makers easily evaluate the effect of support scheme. Current policy for BESS installation support present additional BESS-related installation policy may give incentives to developers partially, however, the dependence between BESS size and benefit components (SMP and REC) can limit the deployment of the various portfolios of the BESS. Therefore, when improving the current policy in future, addressing the dependence between the technical aspects of battery size and the benefit components separately by the technical and economical parts is needed to set the suitable compensation rules for the renewable generation and BESS.

The Effects of $PGF_2{\alpha}$ on Sexual Activity and Semen Collection Training (Prostaglandin $F2{\alpha}$ 투여가 수퇘지의 성행동과 정액 채취 훈련에 미치는 영향)

  • Hong, Joon-Ki;Ryu, Jae-Weon;Cho, Kyu-Ho;Kim, Myung-Jick;Park, Jun-Chul;Kim, In-Cheul;Jung, Il-Byung
    • Journal of Embryo Transfer
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    • v.24 no.1
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    • pp.29-32
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    • 2009
  • Prostaglandin $F_2{\alpha}$ ($PGF_2{\alpha}$) can facilitate release of epinephrine from the adrenal gland. The objective was to extend these findings and determine the effects of $PGF_2{\alpha}$ on sexual activity and semen collection training in sexually inexperienced boars. Boars (n=32; $281{\pm}18$ days of age) were moved individually once weekly to a semen collection room equipped with an artificial sow. Before entering the semen collection room, boar received i.m. treatments of $PGF_2{\alpha}$ at doses of 5 (n=8), 10 (n=8), or 20 (n=8), and control boar (n=8) were not treated. Reaction time (elapsed time after entering collection pen until the start of mounting) for boars receiving 5mg ($3.3{\pm}0.9\;min$), 10mg ($3.3{\pm}0.8\;min$) $PGF_2{\alpha}$ was shorter (p<0.05) than for controls ($6.7{\pm}0.9min$). Duration of ejaculation (min) per session was longer (p<0.05) for $PGF_2{\alpha}$ (10 mg, 20 mg)-treated boars ($7.3{\pm}0.7\;min$, $6.9{\pm}0.7\;min$), compared to control ($3.4{\pm}0.8\;min$). The number of training session per boars was less (p=0.056) for $PGF_2{\alpha}$ 10mg-treated boars ($1.0{\pm}0.4$), compared to control ($2.0{\pm}0.4$). Semen characteristic such as volume, concentration, the number of total ejaculated sperm, were similar for $PGF_2{\alpha}$-treated and controls. There was no apparent difference on sperm movement characteristics (Mot: motility, VCL : curve linear velocity, VSL : straight line velocity, VAP : average path velocity, LIN : linearity) after semen preservation by collected with or without $PGF_2{\alpha}$ treatment. In summary, administration of $PGF_2{\alpha}$ in boars increased the sexual activity and facilitated the training boars to mount an artificial sow for semen collection, but did not affect semen characteristic.

Metarercariae of Echinochusmus japonicus Encysted in a Fresh Water Fibh, Pseudorasboru purva, and Their Development in Experimental Mice (참붕어(Pseudorasbora parva)에서 분리한 Echinochasmus japonicus 피낭유충 및 마우스 실험감염)

  • 제종일;홍성종
    • Parasites, Hosts and Diseases
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    • v.23 no.2
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    • pp.221-229
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    • 1985
  • The echinostomatid metacercariae encysted in the gill of the fresh water fish, Pseudorasbora larva were identified through obtaining adult worms after eBperimental infection to mice. In addition, a brief course of worm development and maturation was observed in this experimental host. The results were as follows: 1. The echinostomatid metacercariae were elliptical, golden yellow, 0.073∼0.078 mm long and 0.0541∼0.065 mm wide. Their head portions were characterized by the presence of a head crown armed with collar spines of total 24 in number and interrupted at the mid-dorsal side of the oral sucker. 2. The average rate of worm recovery froth 12 mice (on the 1-2lth postinfection days) was 19.4 % and the rate revealed no decrease in accordance with the increase of infection duration. The worms were collected chiefly from the lower part of the small intestine. 3. After the infection, their sexual maturation was attained in 5 days and their growth in size nearly completed in 7 days. The early growth curve of genital organs was S shape while that of nongenital organs was C form. In 5 day old worms, 1 or 2 eggs were found from their uteri and the stools of mice revealed echinostomatid eggs from the 5-6th postinfection day. 4. The 7 day old adult worms were ovoid in shape, 0.54-0.69 mm long and 0.29-0.34 mm wide, and characterized by a well developed head crown with 24 collar spines and vitelline follicles distributed from the acetabular level down to the posterior end of body. Based on these characters they were identified to be Echinochasmus japonicus Tanabe, 1926. From these results, it is verified that p. larva is one of the second intermediate hosts of 5. jatonicus in Korea.

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Development of spatial dependence formula of FORGEX method using rainfall data in Korea (우리나라 강우 자료를 이용한 FORGEX 기법의 공간상관식 개발)

  • Kim, Sunghun;Ahn, Hyunjun;Shin, Hongjoon;Heo, Jun-Haeng
    • Journal of Korea Water Resources Association
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    • v.49 no.12
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    • pp.1007-1014
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    • 2016
  • The FORGEX (Focused Rainfall Growth Extension) method was developed to estimate rainfall quantiles in the United Kingdom. This method does not need any regional grouping and can estimate rainfall quantiles with relatively long return period. The spatial dependence formula (ln $N_e$) was derived to consider the distance from growth curve of proper population to the distributed network maximum (netmax) data using the UK rainfall data. For this reason, there is an inaccurate problem in rainfall quantiles when this formula is applied in Korea. In this study, the new formula was derived in order to improve such shortcomings using rainfall data of 64 sites from the Korea Meteorological Administration (KMA). A 42-year period (1973~2014) was taken as the reference period from rainfall data, then the formula was derived using three parameters such as rainfall duration, number of site, area of network. Then the new formula was applied to the FORGEX method for regional rainfall frequency analysis. In addition, rainfall quantiles were compared with those from the UK formula. As a result, the new formula shows more accurate results than the UK formula, in which the FORGEX method by the UK formula underestimates rainfall quantiles. Finally, the new improved formula may estimate accurate rainfall quantiles for long return period.

The Prevalence Rate of Tuberculin Skin Test Positive by Contacts Group to Predict the Development of Active Tuberculosis After School Outbreaks

  • Kim, Hee Jin;Chun, Byung Chul;Kwon, AmyM;Lee, Gyeong-Ho;Ryu, Sungweon;Oh, Soo Yeon;Lee, Jin Beom;Yoo, Se Hwa;Kim, Eui Sook;Kim, Je Hyeong;Shin, Chol;Lee, Seung Heon
    • Tuberculosis and Respiratory Diseases
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    • v.78 no.4
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    • pp.349-355
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    • 2015
  • Background: The tuberculin skin test (TST) is the standard tool to diagnose latent tuberculosis infection (LTBI) in mass screening. The aim of this study is to find an optimal cut-off point of the TST+ rate within tuberculosis (TB) contacts to predict the active TB development among adolescents in school TB outbreaks. Methods: The Korean National Health Insurance Review and Assessment database was used to identify active TB development in relation to the initial TST (cut-off, 10 mm). The 7,475 contacts in 89 schools were divided into two groups: Incident TB group (43 schools) and no incident TB group (46 schools). LTBI treatment was initiated in 607 of the 1,761 TST+ contacts. The association with active TB progression was examined at different cut-off points of the TST+ rate. Results: The mean duration of follow-up was $3.9{\pm}0.9years$. Thirty-three contacts developed active TB during the 4,504 person-years among the TST+ contacts without LTBI treatment (n=1,154). The average TST+ rate for the incident TB group (n=43) and no incident TB group (n=46) were 31.0% and 15.5%, respectively. The TST+ rate per group was related with TB progression (odds ratio [OR], 1.025; 95% confidence interval [CI], 1.001-1.050; p=0.037). Based on the TST+ rate per group, active TB was best predicted at TST+ ${\geq}$ 16% (OR, 3.11; 95% CI, 1.29-7.51; area under curve, 0.64). Conclusion: Sixteen percent of the TST+ rate per group within the same grade students can be suggested as an optimal cut-off to predict active TB development in middle and high schools TB outbreaks.

Predictive value of sperm motility characteristics assessed by computer-assisted sperm analysis in intrauterine insemination with superovulation in couples with unexplained infertility

  • Youn, Joung-Sub;Cha, Sun-Hwa;Park, Chan-Woo;Yang, Kwang-Moon;Kim, Jin-Yeong;Koong, Mi-Kyoung;Kang, Inn-Soo;Song, In-Ok;Han, Sang-Chul
    • Clinical and Experimental Reproductive Medicine
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    • v.38 no.1
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    • pp.47-52
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    • 2011
  • Objective: To determine whether characteristics of sperm motility obtained by computer-assisted sperm analysis (CASA) could predict pregnancy after intrauterine insemination (IUI) in couples with unexplained infertility. Methods: Three hundred eighty-three cycles of intrauterine insemination with superovulation were retrospectively analyzed. Semen analysis was performed with CASA before and after swim-up and the parameters were compared between pregnant and non-pregnant women. Results: The pregnancy rate per cycle was 14.1%. Pregnant and non-pregnant women were comparable in terms of age, infertility duration, the number of dominant follicles. While sperm concentration, motility, and parameters such as average path velocity (VAP) and percentage rapid (RAPID) before semen preparation were significantly different between the pregnancy and non-pregnancy groups, there were no differences in sperm parameters when comparing the two groups after preparation. Using a receiver operating characteristic curve to measure sensitivity and specificity, the optimal threshold value for the predictors of pregnancy was revealed to be a concentration of ${\geq}111{\times}10^6/mL$, a motility of ${\geq}$ 51.4%, and RAPID ${\geq}$ 30.1% before preparation for IUI. Conclusion: Sperm parameters including concentration, motility, and RAPID before sperm preparation could have predictive value for pregnancy outcome after intrauterine insemination with superovulation in couples with unexplained infertility, and would be helpful when counseling patients before they make the decision to proceed with IVF/ICSI-ET.