• 대한간호학회지
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• 제39권3호
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• pp.349-356
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• 2009

Purpose: The purpose of this study was to identify the influence of the type-D personality on quality of life and illness intrusiveness. Methods: This study was a cross-sectional study. Data were collected using self-reported questionnaire from 200 patients with coronary artery disease(CAD). Variables were measured with the Type-D Scale-14(DS14), Korean Health Related Quality of Life Scale(KoQoLS), and the Illness Intrusiveness Rating Scale(ILRS). Results: Of the patients, 38% were classified as type-D personality. Among the 10 subcategories of quality of life, the highest mean score was bodily pain($5.84{\pm}2.85$) and the lowest was role limitation($1.52{\pm}1.20$). Among 13 item of illness intrusiveness, the highest mean score was health($3.78{\pm}1.73$) and the lowest was family relationships($2.14{\pm}1.58$). There were significant differences in all the subcategories of quality of life between type-D and non type-D except for subcategories of bodily pain and role limitation. However, there were no significant differences in illness intrusiveness between type-D and non type-D. Conclusion: Type-D is an important factor in quality of life in patients with CAD, but no correlations between type-D and illness intrusiveness were found. These results can be used as basic data for developing cardiac rehabilitation programs to improve quality of life in type-D patients.

• 한국융합학회논문지
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• 제9권4호
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• pp.143-150
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• 2018

본 연구는 기체연료레벨 값에 대한 정밀도를 측정하기 위하여 초음파의 음향매칭에 관한 실험적인 분석을 수행한 것이다. 연구 모델은 송신과 수신에너지를 결정시키는 세라믹 어세이 (Ceramic Assay)의 구성요소에 의하여 설계되었다. 실험 장치로는 12V-DC 전원공급장치, Control T1 Board, 오실로스코프 (DSO1072B), 초음파 프로브 그리고 패턴테이블 (Pattern T)able이 사용되었다. 불감지영역에 대한 분석결과 최대피크지점인 2.9V의 시작점을 기준으로 D (0.180m) < E (0.184m) < B (0.204m) < A (0.234m) < F (0.244m) < C (0.247m) 모델 순으로 점차적으로 불감지폭이 증가되는 특성을 확인할 수 있었다. 실험결과로부터 매칭레이어 (Matching Layer)의 치수가 Ø21*3+2t로 설계된 모델에서 가장 우수한 지향성 에너지를 생성할 수 있었다.

• 한국융합학회논문지
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• 제9권8호
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• pp.265-272
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• 2018

본 연구는 독거노인의 치매 위험인자 보유상태가 인지기능 저하에 미치는 영향요인임을 알아보기 위한 서술적 조사 연구이다. 지역사회에 거주하는 독거노인 143명을 대상으로 치매 위험인자를 파악하기 위한 간이 설문지, 노인우울척도, 치매선별용 간이정신상태 검사를 실시하였다. 연구결과, 독거노인의 인지기능에 영향을 미치는 주요 요인은 무학과 초졸 이하의 학력, 연령, 우울상태, 흡연, 여가활동, 성별 순으로 나타났다. 향후 독거노인을 대상으로 치매예방 전략을 마련하기 위해서는 인지기능에 부정적인 영향을 주는 요인을 파악하여 인지건강에 도움을 줄 수 있는 생활습관의 변화와 다각적인 관리방안을 모색해야할 필요성이 있다.

• The Korean Journal of Ecology
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• 제8권2호
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• pp.109-117
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• 1985

This report is a part of the investigations of the secondary vegetation successions carried out and the analysis of soil properties in the burned areas of forest. The fires-crown fire and surface fire-were occurred at April, 1978 and February, 1984. The investigations were carrited out from August 10. 1983 to September 25, 1984. The burned areas studied are located in southern slope of Mt. Ssalibagu (above sea-level, 590m), So-myon, Sungju-gun, Chollanam-do, Korea. The results are as follows: The floristic compositions of the burned area at the 5th year after the fires were 85 families, 250 genera, 321 species and 53 varieties. Among them, 85 families, 127 genera, 129 species and 30 varieties were found in the currently burned area. In all the sampling sites (10*10cm), 31 and 57 species were found in the currently burned and in the 5th years after the fires, respectively. Miscanthus sinensis var. purpurascens, Quercus serrata and Festuca ovina were dominant species in the both areas. Biological spectra in both the burned areas showed $H-D_1-R_5-e$ type. Degree of the succession(DS) was 412-884 in the 5th years passed burned area and it was high level. Species diversity index(H) was 0.59~1.13 and evennes index(e) was 0.43~0.79, these indexes between both areas were different considerably. Indexes of similarity between both areas were different, too, but that between $B_1$ and $B_6$ was the highest (CCj=0.5). Probably this phenomenon is due to the great numbers of the pine trees appeared simulataneously. Content of the organic matter, N, P, K and Ca of soil in the burned area at the 5th years after the fires was lower than that of soil in the currently burned area.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제46권1호
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• pp.3-11
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• 2020

Immunoglobulin G4 (IgG4)-related dacryoadenitis and sialoadenitis (IgG4-DS) are part of a multiorgan fibroinflammatory condition of unknown etiology termed IgG4-related disease (IgG4-RD), which has been recognized as a single diagnostic entity for less than 15 years. Histopathologic examination is critical for diagnosis of IgG4-RD. CD4+ T and B cells, including IgG4-expressing plasma cells, constitute the major inflammatory cell populations in IgG4-RD and are thought to cause organ damage and tissue fibrosis. Patients with IgG4-RD who have active, untreated disease exhibit significant increase of IgG4-secreting plasmablasts in the blood. Considerable insight into the immunologic mechanisms of IgG4-RD has been achieved in the last decade using novel molecular biology approaches, including next-generation and single-cell RNA sequencing. Exploring the interactions between CD4+ T cells and B lineage cells is critical for understanding the pathophysiology of IgG4-RD. Establishment of pathogenic T cell clones and identification of antigens specific to these clones constitutes the first steps in determining the pathogenesis of the disease. Herein, the clinical features and mechanistic insights regarding pathogenesis of IgG4-RD were reviewed.

• 대한토목학회논문집
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• 제40권5호
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• pp.445-454
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• 2020

차량과 충돌 시 분리되지 않는 감충형 슬라이딩 지주는 충돌 초기에 차량과 일체로 되어 강체운동을 한다. 이때 차량의 선형모멘텀이 지주에 전달되면서 차량의 1차 감속을 이루고 이어서 가이드레일 아래에 설치된 Energy-Absorbing Pipe (EAP)가 찌그러지면서 나머지 충돌에너지를 흡수하여 2차 감속을 이룬다. 따라서 EAP는 슬라이딩 지주의 핵심요소이고 그 크기는 지주기초 안에 설치될 수 있어야 한다. 본 논문은 국내 편 지식 표지판에 많이 사용되는 지주와 베이스구조를 합하여 총 507 kg의 무게를 갖는 감충형 슬라이딩 지주에 사용하기 위한 EAP의 개발에 관한 것이다. LS-DYNA프로그램을 이용한 충돌해석을 통하여 EAP구조를 설계하고 실차충돌실험을 통하여 감충성능을 평가하는 과정을 상세히 설명하였다. 본 연구를 통하여 제시된 EAP는 최소 0.9 ton-60 km/h에서 최대 1.3 ton-80 km/h 충돌에 대한 감충성능을 발휘하고 기초길이가 2.7 m 이하로 제약될 때 활용될 수 있다.

• 인터넷정보학회논문지
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• 제16권6호
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• pp.57-67
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• 2015

This paper proposes an Fuzzy-based Risk Reasoning Driving Strategy on VANET. Its first reasoning phase consists of a WC_risk reasoning that reasons the risk by using limited road factors such as current weather, density, accident, and construction, a DR_risk reasoning that reasons the risk by combining the driving resistance with the weight value suitable for the environment of highways and national roads, a DS_risk reasoning that judges the collision risk by using the travel direction, speed. and distance of vehicles and pedestrians, and a Total_risk reasoning that computes a final risk by using the three above-mentioned reasoning. Its second speed reduction proposal phase decides the reduction ratio according to the result of Total_risk and the reduction ratio by comparing the regulation speed of road to current vehicle's speed. Its third risk notification phase works in case current driving speed exceeds regulation speed or in case the Total_risk is higher than AV(Average Value). The Risk Notification Phase informs rear vehicles or pedestrians around of a risk according to drivers's response. If drivers use a brake according to the proposed speed reduction, the precedent vehicles transfers Risk Notification Messages to rear vehicles. If they don't use a brake, a current driving vehicle transfers a Risk Message to pedestrians. Therefore, this paper not only prevents collision accident beforehand by reasoning the risk happening to pedestrians and vehicles but also decreases the loss of various resources by reducing traffic jam.

• Molecules and Cells
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• 제27권1호
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• pp.47-54
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• 2009

A cDNA clone for a transcript preferentially expressed during an early phase of flooding was isolated from Nicotiana tabacum. Nucleotide sequencing of the cDNA clone identified an open reading frame that has high homology to the previously reported glycine-rich RNA-binding proteins. The open reading frame consists of 157 amino acids with an N-terminal RNA-recognition motif and a C-terminal glycine-rich domain, and thus the cDNA clone was designated as Nicotiana tabaccum glycine-rich RNA-binding protein-1 (NtGRP1). Expression of NtGRP1 was upregulated under flooding stress and also increased, but at much lower levels, under conditions of cold, drought, heat, high salt content, and abscisic acid treatment. RNA homopolymer-binding assay showed that NtGRP1 binds to all the RNA homopolymers tested with a higher affinity to poly r(G) and poly r(A) than to poly r(U) and poly r(C). Nucleic acid-binding assays showed that NtGRP1 binds to ssDNA, dsDNA, and mRNA. NtGRP1 suppressed expression of the fire luciferase gene in vitro, and the suppression of luciferase gene expression could be rescued by addition of oligonucleotides. Collectively, the data suggest NtGRP1 as a negative modulator of gene expression by binding to DNA or RNA in bulk that could be advantageous for plants in a stress condition like flooding.

• BMB Reports
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• 제37권3호
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• pp.383-385
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• 2004

RNA interference (RNAi) is a process of sequence-specific gene silencing, which is initiated by double-stranded RNA (dsRNA). RNAi may also serve as an antiviral system in vertebrates. This study describes the inhibition of herpesvirus-6B (HHV-6B) replication by short interference RNAs (siRNAs) that are targeted to the U38 sequence that encodes DNA polymerase. When virus-infected SupT1 cells were treated by siRNA, these cells blocked the cytopathic effect (CPE) and detected the HHV-6B antibody-negative in indirect immunofluorescence assays (IFA). Our result suggests that RNAi can efficiently block Herpesvirus-6B replication.

• 대한한방내과학회지
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• 제23권2호
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• pp.306-312
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• 2002

Systemic Lupus Erythematosus(SLE) is a autoimmune disease characterized by combined symtoms of malar rash, discoid rash, neuropsychiatric disorder, renal disorder, hematologic disorder, photosensitivity immunologic disorder, oral ulcer, anti-nuclear antibody, arthritis, pleuritis and pericarditis, etc. Multiple genetic or environmental causes are supposed to facilitate antiboby production to autoantigen such as ds-DNA, histone, phospholipid, red blood cell, platelet, etc. And defective complementary system fail to remove autoantigen-antibody complex, which deposit in multiple organs and result in inflammatory damages. SLE does not correctly correspond to any specific category of oriental medicine. But, accoring to previous reports, it can be controlled by herb medications used differently patients-to-patients. So we are to report this one SLE case being successfully controlled by classic corticosteroids with herb medications based on oriental diffrential diagnosis of symptoms and signs.