• 제목/요약/키워드: Drug Distribution

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Management Strategy by Evaluation on Comprehensive Health Problem in the Community-dwelling Elderly of Korea (재가노인의 포괄적 건강문제 평가와 관리방안)

  • Lee, Jae-Chang;Kim, Eun-Kyung
    • Journal of Korean Academy of Nursing Administration
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    • 제12권3호
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    • pp.464-472
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    • 2006
  • Purpose: The aim of this study was to define the health problem in the community-dwelling elderly of Korea and to compare differences of CAPs(Client Assessment Protocols) by characteristics. Method: Data was collected by visiting nurse from 556 elderly over 65 years in selected metropolitan areas. To evaluate the functional state of elderly in the community, I used "RAI-MDS HC; Residental Assessment Instrument Minimum Data Set-Home Care(2.0 version)" and established information exchange system among resources, by developing the data into a computer program. Results: The health problem of 'preventive health measures' was the largest(99.6%), and then 'health promotion(85.3%)', 'visual function(75.5%)', 'psychologic drug(68.9%)', 'pain(68.5%)', ‘social function(59.2%)', 'communication disorders(56.2%)', 'environmental assessment(53.2%)', 'depression & anxiety(46.9%)', 'oral health(43.4%)' followed. The number of health problems was average 10.16 in the community-dwelling elderly. Conclusion: The results suggest the need to emphasize the importance of assessment of the health problem of the elderly. We can apply it in the distribution of community resources and the development of service providing programs by figure out the health problem and resource in need for the elderly in the community.

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Epidemiological Survey on Piglet diarrhea in eastern Chonnam province (전남동부지방의 설사자돈에 대한 역학조사)

  • 위성하;박장일;임종수
    • Korean Journal of Veterinary Service
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    • 제19권1호
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    • pp.46-54
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    • 1996
  • This study was perfomed to examine the distribution of causative agent of piglets diarrhea in eastern Chonnam province from February 1994 to March 1995. The causative agents of diarrhea were examined by bacterial culture test, parasitological test and serological test against PED, TGE and Rota. The 35 isolated E. coli were tested for antibiotic sensitivity. The results obtained were as follows. 1. The incidence of 81 piglets with diarrhea was most prevalent as 39.5% in the age of 2 to 4 weeks, compare to 34.6% in the age of 5 to 8 weeks and 16.0% under 1 weeks and 9.9 % in the age of 9 to 11 weeks after birth. 2. The incidence of 81 piglets diarrhea showed bacterial diarrhea(75.3%), viral diarrhea (35.8%) and parasitological diarrhea(18.5%). When compared the isolation frequency of each etiological agent, enteropathogenic E. coli was most prevalent as 55.5% in bacterial diarrhea, rotavlrus enteritis as 18.5% in viral diarrhea and trichuriasis as 13.6% in parasitological diarrhea. 3. The complicated infection of piglets was most prevalent as 41.7% in rotavirus enteritis with enteropathogenic E coli in 24 complicated piglets diarrhea. 4. In antibiotic sensitivity test, isolates showed moderatly resistance to Tobramycin, Amikacin, Imipenem, Trimethoprim/Sulfamethoxazole, Gentamicin, Ampicillin but sensitivty to Ticarcillin/K. The 30 E. coli isolate showed multiple drug resistances in 3 different antibiotics.

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A study on trend of residual changes in blood and eggs of laying hens after oral administration of quinolones (산란계에서 퀴놀론계 약물투여 후 혈장 및 계란내의 잔류함량 변화추이 조사)

  • Sim Ea-Ran;Kim Mi-Hee;Yoo Eun-Ah;Lee Yun-Jung;Chun Soon-Yong;Moon Soo-Pyeong;Hahm Yoo-Sik
    • Korean Journal of Veterinary Service
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    • 제28권3호
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    • pp.245-251
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    • 2005
  • The purposes of this study were to evaluate the distribution of quinolone and to investigate the effects of quinolones (enrofloxacin, ciprofloxacin) in blood(plasma) and eggs of laying hens. Animals were fed quinolones which supplemented with 20, 50, 80 mg/kg of body weight. Blood and egg samples were collected after oral administration and analyzed for quinolones (enrofloxacin, ciprofloxacin) by HPLC. In laying hens, the residue period of enrofloxacin were longer than that of ciprofloxacin and the levels of residues were elavated by drug dosage.

Isolation and Drug Sensitivity of Gram-Negative Rods from Bovine Udder Infections (젖소 유방염(乳房炎)으로부터 Gram 음성간균(陰性桿菌)의 분리(分離) 및 약제감수성(藥劑感受性)에 관(關)한 연구(硏究))

  • Lee, Cha Soo;Park, Cheong Kyu
    • Korean Journal of Veterinary Research
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    • 제20권2호
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    • pp.79-84
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    • 1980
  • One hundred and eighteen cultures of Gram-negative rods isolated from cases of clinical bovine mastitis during lactation were examined for distribution of specific types, and activity of several antimicrobial agents to the isolates was determined by two-fold tube dilution method employing sterile whole milk as fluid medium. Of the isolates, 59.2% were Escherichia coli. Most of the remaining isolates were Klebsiella pneumoniae and Enterobacter aerogenes. Most Gram-negative rods(89.8%) were isolated from acute local and chronic mastitis. The cases of peracute systemic form with a marked symptoms of toxemia were associated with Escherichia coli and Klebsiella pneumoniae. The minimal lethal concentrations (MLC) of gentamicin and oxolinic acid in sterile whole milk were 16-128 times higher than the MLC obtained in trypticase soy broth (TSB), while the MLC of ampicillin and tetracycline in milk increased 2-4 times compared with TSB. Of the drugs tested, gentamicin was the most active antibiotics with MLC of $100{\mu}g/ml$ in sterile whole milk against all of Gram-negative rods isolated from bovine udder infections.

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Antibiotic Resistance of Escherichia coli from Pigs Fed with Antibiotics-containing Feedstuffs (돈유래(豚由來) Escherichia coli의 항생물질내성(抗生物質耐性) 및 전달성내성인자(傳達性耐性因子)에 관(關)하여)

  • Tak, Ryun Bin;Chung, Gill Taik
    • Korean Journal of Veterinary Research
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    • 제16권2호
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    • pp.159-163
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    • 1976
  • One hundred and sixty one Escherichia coli strains isolated from 24 swine (11 swine fed with feedstuffs containing 7.5mg/kg of tetracycline and 13 swine not received antibiotic) were studied for the drug resistance and distribution of R factors. About 42 per cent of E. coli strains isolated from pigs of a herd fed with tetracycline (TC)-containing feeds were resistant to TC, streptomycin(SM), sulfisomidine(SA), ampicillin (AP) and kanamycin (KM), alone or in combination thereof, but none of the swine not receiving antibiotic containing feedstuffs excreted E. coli resistant to these drugs, Among resistant strains, 18.2% were found to be singly resistant to TC, whereas 81.8% were resistant to two or more antibiotics. The most common pattern was the triple resistant to TC, SM and SA(30.3%), and follolwed by double ones to TC and SM(24.2%). About one half of resistant strains carried R factors which were tranferable to the recipients by conjugation. In spite of feeding with feedstuffs containing only TC, high incidences of multiple resistance and R factors were observed in the E. coli isolated from these swine.

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The Impact of Moving Pharmaceutical Products from Prescription Only to Over-the-Counter Status on Consumer Exposure to Advertising

  • Yang, Hae-Kyung
    • International Journal of Human Ecology
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    • 제12권2호
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    • pp.1-12
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    • 2011
  • Many pharmaceutical products are available through prescription (Rx) only status. As a result, access to physicians and insurance coverage play a key role in the use of these products, and therefore may affect the population to whom advertising is targeted at. The movement of pharmaceutical products from prescription (Rx) to Over-the-Counter (OTC), or Rx-to-OTC switch changes the cost of acquiring the drug and therefore may change the incentives manufacturers have at targeting particular population segments. This study examines whether Rx-to-OTC switch changes the frequency and the distribution of who is exposed to pharmaceutical advertising. Using an archive of pharmaceutical advertisements and National Consumer Survey, this study examines how individuals with particular demographic characteristics are exposed to pharmaceutical advertisements before and after drugs are moved from Rx to OTC. The results provide evidence that individual's advertising exposure increases after Rx-to-OTC switch. Moreover, the increase in advertising exposure is greater for the low socioeconomic status (SES) consumers which implies they may get more information about the disease, treatment and product after the Rx-to-OTC switch through advertising. If low SES consumers have more exposure to the advertising after products switched to OTC, then FDA policies regulating this switch should recognize the potential role of advertising providing access to health-related information.

CHRONIC OSTEOMYELITIS ON MANDIBLE INDUCED BY TRIGEMINAL ZOSTER (삼차신경 대상포진에 의한 만성 하악골 골수염)

  • Oh, Jung-Hwan;Yim, Jin-Hyuk
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제33권2호
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    • pp.169-172
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    • 2007
  • The Varicella zoster virus is responsible for two common infectious diseases: chicken pox(Varicella) and shingles(Herpes zoster). Chicken pox is the primary infection. After the initial infection, the virus remains dormant in sensory ganglia until reactivation may occur decades later. The subsequent reactivation is Herpes zoster. Herpes zoster of the trigeminal nerve distribution manifests as painful, vesicle eruptions of the skin and mucosa innervated by the affected nerve. Oral vesicles usually appear after the skin manifestrations. Reports of osteomyelitis of jaw after trigeminal herpes zoster are extremely rare. We report a case of osteomyelitis on mandible caused by herpes zoster infection which was treated by antiviral drug, curettage. At 1 year post-operatively, mandibular mucosa had healed without recurrent sign. But post-herpetic neuralgia is remained.

Chemical and Pharmacological Studies of Saponins with a Focus on American Ginseng

  • Yuan, Chun-Su;Wang, Chong-Zhi;Wicks, Sheila M.;Qi, Lian-Wen
    • Journal of Ginseng Research
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    • 제34권3호
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    • pp.160-167
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    • 2010
  • Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) are the two most recognized ginseng botanicals. It is believed that the ginseng saponins called ginsenosides are the major active constituents in both ginsengs. Although American ginseng is not as extensively studied as Asian ginseng, it is one of the best selling herbs in the US, and has garnered increasing attention from scientists in recent years. In this article, after a brief introduction of the distribution and cultivation of American ginseng, we discuss chemical analysis of saponins from these two ginsengs, i.e., their similarities and differences. Subsequently, we review pharmacological effects of the saponins, including the effects on the cardiovascular system, immune system, and central nervous system as well as the anti-diabetes and anti-cancer effects. These investigations were mainly derived from American ginseng studies. We also discuss evidence suggesting that chemical modifications of ginseng saponins would be a valuable approach to develop novel compounds in drug discovery.

A Study on the Location Improvement of the Pharmaceutical Logistics Center (의약품 물류센터 입지 개선 방안에 관한 연구)

  • Cho, Sam Hyun;Cho, Sang Lee
    • Journal of Korea Port Economic Association
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    • 제35권3호
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    • pp.41-60
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    • 2019
  • This study aims to identify factors that pharmaceutical logistics companies must consider when selecting a logistics center; it also aims to analyze the importance-satisfaction-of these factors by using IPA. The main results are as follows. First, overall, the aforementioned factors are divided into logistics factor, economic factor, environmental factor, and policy factor, and most of the specific attributes of each main factor are less satisfied than the importance. Second, the users of pharmaceutical logistics are divided into producers, distributors, clinics, and pharmacies. The analysis of each user shows a need to improve logistics factors as well as an overinvestment in environmental factors. The results can provide drug distribution companies directions for selecting logistics centers as well as strategic implications.

Technology Trend for the Preparation of Polymeric Particles by SPG Technique (SPG 막유화법을 이용한 고분자 입자 제조기술의 동향)

  • Lee, Sang-Kug;Kim, Sung-Wook;Choi, Kyoung-Ho;Lim, Eun-Hee
    • Elastomers and Composites
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    • 제44권3호
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    • pp.222-231
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    • 2009
  • Shirasu-porous-glass (SPG) membrane emulsification is highly attractive in the field of toner industries, foods and drug delivery systems because of its easy control of particle size in micro-scale, narrow size distribution and multiple emulsion. The particle size and morphology of emulsion droplets can be controlled by changing the type of initiators, additives, monomers, crosslinkers and inhibitors in SPG membrane emulsification. In this paper, principles of SPG membrane emulsification, influence of process parameters and industrial applications have been addressed.