• 정신신체의학
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• 제3권1호
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• pp.11-18
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• 1995

The efficacy of fluoxetine was evaluated in 32 patients with major depression in double-blind amitriptyline-controlled clinical trials. Patients were randomly assigned to 6 weeks of treatment with 20mg/day of fluoxetine and 25-100mg/day of amitriptyline. We used the Hamilton rating scale for depression(HAM-D) and the Clinical Global Improvement(CGI) to evaluate the improvement of depression. In addition, we also used the Covi Anxiety Scale and the Anxiety/Somatization subscale of HAM-D to investigate the relieving effect of anxiety. The improvement by fluoxetine in mean total score of HAM-D and CGI was comparable to amitriptyline. Fluoxetine also reduced anxiety significantly, but there was no difference between fluoxetine and amitriptyline in relieving anxiety symptoms. Fluoxetine showed considerably less adverse effects, especially anticholinergic effect and weight gain than amitriptyline. In conclusion, 20mg/day of fluoxetine was sufficiently effective in the treatment of depressive patients and was better tolerated than amitriptyline.

• Journal of Biosystems Engineering
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• 제14권1호
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• pp.41-48
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• 1989

In order to provide a basic information for the government policy in the future, rice milling costs of Small Capacity Farm-house Rice Whiteners (SCFRW) were estimated by surveying and analyzing the major factors to affect their costs. Two types of SCFRW having one stage and two stage milling process and two rice varieties, Tong-il and Akibare, were considered for their cost estimation, respectively. Also, their costs were compared with those of Private Custom-work Mill in order to determine its economical feasibility. The results were concluded as follows; 1. Major factors to affect the costs were annual milling quantity, purchase price of SCFRW and grain milling loss. 2. Total milling costs of SCFRW were a function of annual milling quantity. These costs decreased rapidly as annual milling quantity increased. 3. In comparison of milling costs between single pass type and double pass type SCFRW, the former was more economical than the latter. 4. Also, in comparison of milling costs between two varieties by using SCFRW, Akibare was less expensive than Tong-il. 5. In comparison with private Custom-work Mill, both single pass and double pass type SCFRW were less economical than private Custom-work Mill. 6. In order to have an economical feasibility, SCFRW should be designed and developed to reduce its milling loss and purchase price.

• 제어로봇시스템학회논문지
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• 제12권2호
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• pp.145-153
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• 2006

An optimal capturing trajectory for a moving object is proposed in this paper based on the observation that a single-curvature path is more accurate than double-or triple-curvature paths. Moving distance, moving time, and trajectory error are major factors considered in deciding an optimal path for capturing the moving object. That is, the moving time and distance are minimized while the trajectory error is maintained as small as possible. The three major factors are compared for the single and the double curvature trajectories to show superiority of the single curvature trajectory. Based upon the single curvature trajectory, a kinematics model of a mobile robot is proposed to follow and capture the moving object, in this paper. A capturing scenario can be summarized as follows: 1. Motion of the moving object has been captured by a CCD camera., 2. Position of the moving object has been estimated using the image frames, and 3. The mobile robot tries to follow the moving object along the single curvature trajectory which matches positions and orientations of the moving object and the mobile robot at the final moment. Effectiveness of the single curvature trajectory modeling and capturing algorithm has been proved, through simulations and real experiments using a 2-DOF wheel-based mobile robot.

• Archives of Plastic Surgery
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• 제34권1호
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• pp.105-110
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• 2007

Purpose: The major drawback of submuscular augmentation of the ptotic breast is a "double-bubble" deformity. If a traditional mastopexy is added to correct the ptosis, there would be additional scars. This article describes simultaneous periareolar mastopexy with dual plane or subfascial breast augmentations. Methods: A series of 81 patients with grade I or II ptosis underwent the procedure from 1999 to 2005. Out of these, dual plane augmentation was done in 71 cases and subfascial plane in 10. After periareolar skin excision, an incision is made perpendicularly down to the fascia of pectoralis. At the lower pole, all breast implants are inserted into the subfascial plane. In case of upper pole thickness of above 20 mm, we inserted the implant into the subfascial plane, whereas below 20 mm, we inserted that into the submuscular plane. Results: No major complications were noted and patients' satisfactory score was high. This technique avoids the "double-bubble" deformity and leaves a minimal periareolar scar. Conclusion: Simultaneous periareolar mastopexy/breast augmentation is useful for correction of the ptotic breast, increasing the volume of breast and providing the natural breast shape with minimal scars. We consider that subfascial plane augmentation with periareolar mastopexy to be an alternative for cases with breast upper pole thickness of at least above 20 mm.

• Journal of Nutrition and Health
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• 제33권5호
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• pp.491-496
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• 2000

Food intake is regulated by both central and peripheral mechanisms. In the central nervous, the hypothalamus acts for autonomic and endocrine homeostasis. The paraventricular nucleus(PVN) of hypothalamus is an imprtant site of interaction in central feeding pathways. Neuroepetide Y(NPY)is one of the most powerful neurochemical stimulants of food intake known. Also brain nitric oxide(NO), known as neurotransmitter, is involved in the mechanisms that regulate food intake. In this experiment, 24h fasting mice and anorexia mutant mice have been to examine the expression of NPY, which is the major neuropeptide increasing food intake. Double staining with NPY and nicotinamide-adenine-dinucleotide-phosphate diaphorase(NADPH-d), followed by immunohistochemical method and image analysis, have been used to observe coexisting neurons and the level of expression of each neurons. The results were as follows. 1) NPY-immunoreactivitys reduced immune response of the hypothalamus, particularly paraventricular nucleus(PVN), in anorexia mutant mice. Decreased level of NPY is assumed to be a major pathological factor in anorexia mutant mice. On the other hand, PVN in hypothalamus of fasting mice showed increased immunoreactivity which is in agreement of other researchers. 2) NPY and NADPH-d double staining revealed coexisting neurons in the cerebral cortex. Fasting mice had a tendency to have increased level of coexisting neurons compared to the control group. Compared to the control group, fasting mice express is not increase level of NPY-immunoreactivity, while anorexia mutant mice tended to have a decreased level.

• Advances in concrete construction
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• 제13권3호
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• pp.265-279
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• 2022

The roughness of substrate concrete interfaces before new concrete placement has a major effect on the interface bond behaviour. However, there are challenges associated with the consistency of the final roughness interface prepared using conventional roughness preparation methods which influences the interface bond performance. In this study, five quantitative interface roughness textures with different roughness tooth angles, depths, and tooth distribution were created to ensure consistency of interface roughness and to evaluate the bond behaviour at a precast and new concrete interface using the splitting tensile test, slant shear test, and double-shear test. In addition, smooth interface specimens and two separate the pitting interface roughness were also utilized. Obtained results indicate that the quantitative roughness has a very limited effect on the interface tensile bond strength if no extra micro-roughness or bonding agent is added at the interface. The roughness method however causes enhanced shear bond strength at the interface. Increased tooth depth improved both the tensile and shear bond strength of the interfaces, while the tooth distribution mainly influenced the shear bond strength. Major failure modes of the test specimens include interface failure, splitting cracks, and sliding failure, and are influenced by the tooth depth and tooth distribution. Furthermore, the interface properties were obtained and presented while a comparison between the different testing methods, in terms of bond strength, was performed.

• 서비스연구
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• 제11권2호
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• pp.95-105
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• 2021

본 연구는 KSC(kano, Score Model, Concept Position)평가방법을 활용하여 제공할 서비스디자인 만족도에 대한 정확도를 높이는 것이 연구의 목적으로 부산지역을 중심으로 6개 지점을 운영하고 있는 P사 헬스장을 중심으로 건강한 뉴실버세대를 위한 다양한 헬스장 서비스모델을 제시하여 사례연구를 진행하였다. 더블다이어몬드(Double Diamond)방법을 활용하여 P사의 5개 지점 중 연산점을 중심으로 사례연구를 진행하였는데 이는 연산점을 중심으로 노인을 위한 다양한 여가생활 인프라가 잘 구축 되어 있었기 때문이다. 본 연구를 통하여 고객에 대한 다양한 인사이트(Insight)를 추출하였고 발굴한 인사이트(Insight)를 기반으로 관리자와 트레이너의 관점에서 서비스디자인 모델을 최종적으로 9가지 도출하였다. 최종적으로 도출한 9가지 모델을 기반으로 카노(Kano)만족도 평가, 스코어모델(Concept Score), 콘셉트포지션(Concept Position)평가를 통하여 9가지 제시한 안들 중 3, 6번을 제외한 모든 안들이 유효하다는 것을 알 수 있었고 최종적으로 투자비용과 효과성으로 구분하여 실행 로드맵을 제안하였다.

• 동의신경정신과학회지
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• 제20권3호
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• pp.169-188
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• 2009

Objectives : The purpose of this research is to examine the effect of Bunsimgi-eum on the chest discomfort of Hwa-byung's major symptom. Methods : In this randomized, double blinded, placebo-controlled study, we planned to give Bunsimgi-eum or controlled medication for major symptoms of Hwa-byung. As preparatory research, 100 mm Visual Analogue Scale(VAS) for chest discomfort, the Hwa-byung' major symptom was measured as the 1st evaluative instrument, and Likert scale for major symptom of Hwa-byung, Korean State-Trait Anger Expression Inventory(STAXI-K), Korean State-Trait Anxiety Inventory(STAI-K), Korean Beck's Depression Inventory(BDI-K) and Heart Rate Variability(HRV) were also measured as the 2nd evaluative instrument at the before treatment. Results : Clinical characteristics-vital signs & demographic characteristics showed no significant difference between both groups. The characteristics of disease-chief complaint, pattern Identification, period, etiological factor, etc, also showed no significant difference between both groups. There were almost no Coincidence between pattern identification & weight of Hwa-byung's major symptoms. The results of Chest PA, EKG and clinicopathologic examination showed no significant difference between both groups. There were no significant difference between both groups in all valuation scales; 100 mm Visual Analogue Scale for chest discomfort, the Hwa-byung' major symptom was measured as the 1st evaluative instrument, and Likert scale for major symptom of Hwa-byung, STAXI-K, STAI-K, BDI-K and HRV. Conclusions : We considered that establishment of experimental group and controlled group was objective and worth conducting this research. And this methodology is expected to be applied to the subsequent research. And also, we hope to make up for this study through various study and discussion.

• 대한기계학회논문집A
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• 제34권9호
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• pp.1217-1225
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• 2010

소듐을 냉각재로 사용하는 고속로의 증기발생기에서는 소듐과 물의 화학적 반응을 최소화하는 것이 중요한 문제이다. 소듐과 물의 반응 가능성을 줄여 증기발생기의 신뢰성을 향상시키기 위한 한가지 방안으로 이중벽관을 전열관으로 사용하는 증기발생기를 개발하고 있다. 이 증기발생기에서 중요한 현안은 이중벽관에서의 열전달 성능을 향상시키는 문제와 원자로 운전 중에 소듐과 물 반응사고가 일어나기 전에 전열관의 파손을 감지하는 기술을 개발하는 것이다. 이 논문에서는 이 현안을 극복할 수 있는 방안을 제시하였고, 이 기술을 활용하여 증기발생기의 개념을 설계하였다. 또한 이 개념에 적용되는 이중벽관을 설계 및 예비 제작하여 기계적 시험을 수행하였다.

• 에너지공학
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• 제1권1호
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• pp.66-75
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• 1992

이중창의 열전달 성능을 수치해석과 실험적 방법을 통하여 조사하였다. 이중창 사이의 간격이 0.5cm에서 10cm사이의 실제적인 범위에서 이중창 사이의 간격이 작을 때에는 전도에 의한 열전달이 두드러졌으며 이중창 사이의 간격이 넓어지고 Rayleigh 수가 높은 영역에서는 대류에 의한 열전달이 크게 나타나 이중창 간격이 넓어진 이점을 크게 상쇄시켰다. 이와 같은 이중창 단열문제에 대한 보완책으로 이중창 중앙에 하나의 유리창을 더 설치한 3중창 경우에 대해 대류열전달 감소효과와 복사열차폐(radiation shield) 효과를 검토하였으며 또한 이중창 중간 높이에 스페이서(spacer)를 설치하여 대류유동 강도를 줄이는 방안 등에 대한 분석이 이루어졌다. 3중창을 사용한 경우에는 이중창에 비해 30-50%, 이중창에 스페이서를 설치한 경우에는 l0% 정도의 에너지 절약 효과를 기대할 수 있다.