• 제목/요약/키워드: Dose variation

검색결과 410건 처리시간 0.021초

AIDS환자 치료를 위한 점진적 약물감소기법에 감염속도상수가 미치는 영향 (The influence of infection ratio on Gradual Reduction of Drug Dose for the treatment of AIDS patients)

  • 이강현;조남훈
    • 전기학회논문지
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    • 제56권1호
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    • pp.174-182
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    • 2007
  • In this paper, we study the influence of infection ratio on gradual reduction of drug dose for the five state HIV infection model that explicitly includes the population of the virus. We first compute all equilibrium points of the model and investigate the stabilities of them. As a result, a bifurcation diagram is obtained which shows a change in the equilibrium points, or in their stability properties, as the drug effect $\eta$ is varied from 0 to 1(alternatively, drug dose is changed from 1 to 0). Based on the bifurcation diagram, we show that the gradual reduction of drug dose can be applied for the treatment of AIDS patients. Moreover, we analyze the influence of the variation of infection ratio on the gradual reduction treatment. Computer simulation results are also presented to validate the proposed results.

고에너지 전자선의 흡수선량 측정에 있어서 TLD의 유용성 (Measurement of Absorbed Dose for High Energy Electron using $CaSO_4:Tm$ - PTFE TLD)

  • 박명환;김도성
    • 대한방사선기술학회지:방사선기술과학
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    • 제23권1호
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    • pp.97-101
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    • 2000
  • In this study, the highly sensitive $CaSO_4:Tm$-PTFE TLDs has been fabricated for the purpose of measurement of high energy electron. $CaSO_4:Tm$ phosphor powder was mixed with polytetrafluoroethylene(PTFE) powder and moulded in a disk type(diameter 8.5 mm. thickness $90\;mg/cm^2$) by cold pressing. The absorbed dose distribution and ranges for high energy electron were measured by using the $CaSO_4:Tm$-PTFE TLDs. The ranges determined were $R_{100}=14.5mm$, $R_{50}=24.1mm$ and $R_P=31.8mm$, respectively and the beam flatness, the variation of relative dose in 80% of the field size, was 4.5%. The fabricated $CaSO_4:Tm$-PTFE TLDs nay be utilized in radiation dosimetry for personal, absorbed dose and environmental monitoring.

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방사선에 조사된 EPR 의 전기적 특성에 관한 연구 (A Study on Electrical properties of EPR by Irradiated by X-rays)

  • 이성일;김귀열;이호식;이희갑
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2002년도 추계학술대회 논문집 Vol.15
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    • pp.565-568
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    • 2002
  • The value of charge current, discharge current, $\varepsilon_r$' $\varepsilon_r"$, residual voltage was measured inorder to investigate electric properties in Ethylene Prophylene Rubber for is irradiated $CO^{60}\gamma$ ray 0-38.1 Mrad. The value of charge current and the discharging current of the EPR is influenced by $CO^{60}-{\gamma}$-irradiation dose The charging current and the discharging current of EPR increase, depending on the ratio of degradation. As the irradiation dose is increased, the peak of residual voltage moves to the slorter time. The properties specific electric constant due to time variation was appeared dispersion by plentiful $CO^{60}-{\gamma}$-irradiation dose. The increase of peak in $\varepsilon_r"$ is attrib uted to the irratiation dose almost proportionally.

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EPR의 전기특성에 미치는 방사선의 영향 (Effect of the Co$^{60}$ -Rays due to Electric properties of EPR-)

  • 이성일
    • 대한안전경영과학회:학술대회논문집
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    • 대한안전경영과학회 2002년도 추계학술대회
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    • pp.253-259
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    • 2002
  • The value of charge currnet, discharge current, ${\varepsilon}r^'$,${\varepsilon}r^{'}$ residual voltage was measured inorder to investigate electric properties in Ethylene Prophylene Rubber for is irradiated C0$^{60}$$\gamma$ ray 0~38.1 Mrad. The value of charge current and the discharging current of the EPR is influenced by C0$^{60}$-$\gamma$- irradiation dose. The charging current and the discharging current of EPR increas, depending on the ratio of degradation. As the irradiatin dose is increased, the peak of residual voltage moves to the slorter time. The properties specific electric constant due to time variation was appeared dispersion by plentiful C0$^{60}$$\gamma$- irradiation dose. The increase of peak in ${\varepsilon}r^{'}$ is attrib uted to the irratiation dose almost proportionally.

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LCD 제조공정의 이온화 장치에 대한 전리방사선 지역노출특성 분석 (Analysis of Local Exposure Levels of Radiation Emitted from Soft X-ray Ionizers in LCD Manufacturing Processes)

  • 김준범;정은교;정기효
    • 한국산업보건학회지
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    • 제31권4호
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    • pp.342-352
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    • 2021
  • Objectives: This study analyzed the local exposure levels of radiation emitted from the equipment with soft X-ray ionizers to investigate the radiation exposure levels in Liquid Crystal Display(LCD) manufacturing processes. Methods: This study measured the local radiation levels for the equipment installed in two LCD manufacturing companies. The equipment were installed at diverse processes and equipped with various number of ionizers. The local radiation levels were measured on the surface of the equipment by using direct reading equipment, and the measurements were converted into annual effective dose by considering the radiation exposure time of workers. Statistical analyses were performed to investigate the radiation exposure characteristics. Results: Annual effective doses for 97.6% of the equipment being measured were less than 1 mSv. However, the range of annual effective doses was 0.004 mSv ~ 2.167 mSv, which indicated a large variation among the equipment. Statistical analyses of the study found that this large variation was raised due to improper shielding of the equipment rather than process and/or equipment characteristics. To pinpoint the cause of this large variation in annual effective dose, this study improved the shielding of the equipment being radiated over 1 mSv and found that their average effective dose was reduced from 1.604 mSv to 0.126 mSv after shielding improvement. Conclusions: Relatively high exposure levels of radiation were observed in some equipment where their shielding were insufficiently thick and/or sealed. This finding implies that the shielding of the equipment is an important engineering countermeasure to control the radiation exposure levels in industries.

The Experience in Dose Measurement of IVR with Glass Dosimeter System

  • Nishizawa, Kanae;Moritake, Takashi;Iwai, Kazuo;Matsumaru, Yuji;Tsuboi, Koji;Maruyama, Takashi
    • 한국의학물리학회:학술대회논문집
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    • 한국의학물리학회 2002년도 Proceedings
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    • pp.269-271
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    • 2002
  • It is reported that exposure for the patient and the medical staff from IVR is large. Direct measurement of patient exposure is difficult, since the measurement disturbs reading of images. The fluorescence glass-dosimeter system consisting of small-size glass chips is developed in recent years. Owing to its small size and physical characteristics, direct monitoring of surface dose may be feasible. The dose measurement for patient and medical staff during head interventional radiology (IVR) examinations was tried by using the fluorescence glass-dosimeter system. A dose response of the glass dosimeter is almost linear in large dose range but its energy dependency is high. About 20% variation of sensitivity was observed in the effective energy of 45-60keV which was used in IVR. In spite of this shortcoming, the fluorescence glass-dosimeter system is a convenient means for a dose monitoring during IVR performance.

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ML-15MDX 술중조사용 Applicator에 의한 전자선선량 특성 (Dose Characteristics for IORT Applicator of ML-15MDX Electron Beam)

  • 최태진;이호준;김영애;김진희;김옥배
    • Radiation Oncology Journal
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    • 제11권2호
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    • pp.455-461
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    • 1993
  • Experimental measurements of dose characteristics with pentagonal applicator at nominal energy of 4, 6, 9, 12 and 15 MeV electron beam were performed for intraoperative radiotherapy (IORT) in ML-15MDX linear accelerator. This paper presents the percent depth dose, surface dose, beam flatness and output factors of using the IORT applicator in different electron beam energy. The output factor showed as a 24 percent higher in IORT applicator than that of reference $10{\times}10cm^2$ applicator. The surface dose of using the IORT applicator showed 7.7 and 2.7 percent higher than that of reference field in 4 and 15 MeV electron beam, respectively. In our experiments, the variation of percent depth dose was very small but the output factor and flatnees at 0.5 cm depth have showed a large value in IORT applicator.

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정류방식에 따른 장치의 정확도와 출력 파형의 비교 (Comparison of Accuracy and Output Waveform of Devices According to Rectification Method)

  • 이인자
    • 대한방사선기술학회지:방사선기술과학
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    • 제41권6호
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    • pp.603-610
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    • 2018
  • This study examined the following: accuracy of the exposure conditions in the inverter device and three-phase device; output waveform over the exposure conditions; and average and standard deviation of the output waveform. After assessing whether the dose corresponding to the theoretical dose was presented, the following conclusions were obtained: 1. The accuracy of the tube voltage(kVp) and tube current(mA) exposure time(sec) was within the tolerable level prescribed in Korea's Safety Management Standards. In the error, Inverter device was large the tube voltage and exposure time, the three-phase device was large the tube current. 2. In terms of the output waveform of the exposure conditions and the average and standard deviation of the output waveform, the higher tube voltage and larger tube current resulted in greater standard deviation in pulsation. Moreover, the standard deviation of pulsation was shown to be greater in the inverter device than the three-phase device; there was also greater standard deviation in the inverter device considering the exposure time. 3. Regarding the exposure conditions over the output dose, all linearity showed the coefficient of variation which had an allowable limit of error within 0.05. Although the output dose ratio for the inverter device was 1.00~1.10 times no difference that of the three-phase device, there was almost no difference in dose ratio between the tube currents.

Comparison of effective dose for imaging of mandible between multi-detector CT and cone-beam CT

  • Jeong, Dae-Kyo;Lee, Sang-Chul;Huh, Kyung-Hoe;Yi, Won-Jin;Heo, Min-Suk;Lee, Sam-Sun;Choi, Soon-Chul
    • Imaging Science in Dentistry
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    • 제42권2호
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    • pp.65-70
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    • 2012
  • Purpose : The aim of this study was to compare the effective dose for imaging of mandible between multi-detector computed tomography (MDCT) and cone-beam computed tomography (CBCT). An MDCT with low dose technique was also compared with them. Materials and Methods : Thermoluminescent dosimeter (TLD) chips were placed at 25 organ sites of an anthropomorphic phantom. The mandible of the phantom was exposed using 2 different types of MDCT units (Somatom Sensation 10 for standard-dose MDCT, Somatom Emotion 6 for low-dose MDCT) and 3 different CBCT units (AZ3000CT, Implagraphy, and Kavo 3D eXaM). The radiation absorbed dose was measured and the effective dose was calculated according to the ICRP 2007 report. Results : The effective dose was the highest for Somatom Sensation 10 (425.84 ${\mu}Sv$), followed by AZ3000CT (332.4 ${\mu}Sv$), Somatom Emotion 6 (199.38 ${\mu}Sv$), and 3D eXaM (111.6 ${\mu}Sv$); it was the lowest for Implagraphy (83.09 ${\mu}Sv$). The CBCT showed significant variation in dose level with different device. Conclusion : The effective doses of MDCTs were not significantly different from those of CBCTs for imaging of mandible. The effective dose of MDCT could be markedly decreased by using the low-dose technique.

유방암 환자의 Field-in-Field Technique 치료 시 호흡의 움직임에 따른 선량 평가 (Evaluation of the Dose According to the Movement of Breath During Field-in-Field Technique Treatment of Breast Cancer Patients)

  • 권경태
    • 대한방사선기술학회지:방사선기술과학
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    • 제41권6호
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    • pp.561-566
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    • 2018
  • Field-in-Field Technique is applied to the radiation therapy of breast cancer patients, and it is possible to compensate the difference in breast thickness and deliver uniform dose in the breast. However, there are several fields in the treatment field that result in a more complex dose delivery than a single field dose delivery. If the patient's respiration is irregular during the delivery of the dose by several fields and the change of respiration occurs, the dose distribution in the breast changes. Therefore, based on the computed tomography images of breast cancer patients, a human model was created by using a 3D printer (Builder Extreme 1000) to describe the volume in the same manner. A computerized tomography (CT) of the human body model was performed and a treatment plan of 260 cGy / fx was established using a 6-MV field-in-field technique using a computerized treatment planning system (Eclipse 13.6, Varian, USA). The distribution of the dose in the breast according to the change of the respiration was measured using a moving phantom at 0.1 cm, 0.3 cm, 0.5 cm amplitude, using a MOSOXIDE Silicon Field Effect Transistor (MOSFET, Best Medical, Canada) Were measured and compared. The distribution of dose in the breast according to the change of respiration showed similar value within ${\pm}2%$ in the movement up to 0.3 cm compared to the treatment plan. In this experiment, we found that the dose distribution in the breast due to the change of respiration when the change of respiration was increased was not much different from the treatment plan.