• Title/Summary/Keyword: Dosage strength

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Effect of PVA Fiber and Silica Fume Addition on Chloride Penetration Resistance of Alkali-Activated Slag (PVA 섬유와 실리카흄 첨가가 알칼리 활성 슬래그의 염화물 침투 저항성에 미치는 영향)

  • Yoon, Hyun No
    • Journal of Urban Science
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    • v.12 no.2
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    • pp.13-18
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    • 2023
  • This study investigates the effect of polyvinyl alcohol (PVA) fiber and silica fume addition on the chloride penetration resistance of alkali-activated slag. Silica fume was added to replace slag at the dosage of 0, 5, 10, and 20% by weight of the binder, while PVA fiber was added at the dosage of 0, 1, and 2% by volume of the mixture. Samples were synthesized via alkali activator with 1.0 of silicate modulus and cured at room temperature for 28 days. Compressive strength test, permeable voids volume test, water absorprtion test, and rapid chloride penetration test were conducted for measuring the charaterisitics of alkali-activaed slag. The results showed that increasing silica fume content up to 10% in alkali-activated slag improved compressive strength and chloride penetration resistance. Addition of PVA fibers up to 1% by volume enhanced strength and chloride penetration resistance, but exceeding this led to reduced strength and durability due to increased void formation in the matrix.

Formulation and Pharmaceutical Properties of Mucoadhesive Film Containing Dipotassium Glycyrrhizate (구내염증 치료용 구강점막 필름제의 제제설계와 약제학적 성질)

  • Rhee, Gye-Ju;Lee, Duk-Keun;Sin, Kwang-Hyun;Park, Chong-Bum
    • Journal of Pharmaceutical Investigation
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    • v.29 no.2
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    • pp.127-136
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    • 1999
  • In order to eliminate demerits of conventional dosage forms, dipotassium glycyrrhizate was formulated as a slim mucoadhesive film type dosage form. The mucoadhesive drug layer gel containing dipotassium glycyrrhizate was prepared using $Noveon^{\circledR}$ AA-1, hydroxypropylcellulose-M, ethylcellulose N 100 and citric acid, and the protective layer gel by using ethylcellulose N 100, $Eudragit^{\circledR}$ RS and castor oil. The viscosity of drug layer gel of mucoadhesive film was enhanced as the increased amount of $Noveon^{\circledR}$ AA-1 or hydroxypropyl cellulose-M. The drug content was unifonnly $1160{\pm}14.6\;{\mu}g$, and was varied within 3.5%. The optimum film dosage form showed a good fluidity and malleability of drug layer, with 179 g of thickness, pH 5.7, 411 min of in vitro adhesion time and 172 g in gravity adhesive strength. The release time of drug from the mucoadhesive film was significantly shorter but was delayed when polymers such as ethylcellulose was added. From these results, the new mucoadhesive film may be effective for the treatment of aphthous stomatitis.

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Comparative Characterization Study on Quality Attributes of Vegetable and Gelatin as Capsule Shell of Soft Capsule (연질캡슐 피막물질로서 식물성 성분 원료와 젤라틴에 대한 품질특성 비교)

  • Kim, Dong Wook;Weon, Kwon Yeon
    • YAKHAK HOEJI
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    • v.59 no.2
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    • pp.70-76
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    • 2015
  • A Softgel is an oral dosage form for medicine similar to capsules and softgel dosage form offers several advantages over other oral dosage forms, such as delivering a liquid matrix designed to solubilize and improve the oral bioavailability of a poorly soluble compound as a unit dose solid dosage form, delivering low and ultra-low doses of a compound. This study aimed to qualify a proprietary vegetable soft capsule which contains modified starch and carrageenan as capsule shell components compare to the conventional gelatin softgel. Four kinds of samples were prepared with vegetable and gelatin capsule shell, respectively. Morphology of capsule shell, mechanical strength of capsule, and hygroscopic properties were studied for comparing the quality attributes of softgel. Short-term stability against heat and moisture was also investigated in this study. Vegetable capsule shell showed better mechanical strength, physical stability and disintegration time for temperature and humidity than those of conventional gelatin capsule shell with four different filling materials used frequently as soft capsule form. Conclusively, this vegetable capsule shell polymer system can replace easily gelatin-shell systems and additionally allows encapsulation of lipid fills at high temperatures that are semisolid or solid-like at room temperature.

Performance of Steel Fiber Reinforced Shotcrete using Alkali Free Based Accelerator (알칼리 프리계 급결제를 사용한 강섬유 보강 숏크리트의 성능 평가)

  • Baek, Chul-Woo;Park, Chan-Gi;Jun, Oun-Jung;Won, Jong-Pil
    • Journal of The Korean Society of Agricultural Engineers
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    • v.46 no.3
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    • pp.65-72
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    • 2004
  • Modern underground and tunnel works that the wet type shotcrete is getting widely designed and applied in a large scale project. Further to its applications, the needs of improving the performance of the shotcrete, such as new and developed additives and accelerators fur increasing the performance of shotcrete, become the most important issue in the field. The main objective of this study evaluated to performance of steel fiber reinforced shotcrete using alkali free based accelerator for the durability and high quality of shotcrete. The major test variables are accelerator type and its dosage. One type silicate based accelerator and one type aluminate based accelerator and one type alkali free based accelerator were used. The dosage of accelerators is determined by the manufactures and laboratory test condition. Compressive strength test results showed that the dosage of silicate and aluminate based accelerators caused reduction of mechanical properties of shotcrete. Compressive strength of alkali free based accelerator is more stable than of silicate and aluminate based accelerators. Also, according to the compressive strength and flexural test results, it was found that steel fiber reinforced shotcrete used alkali free based accelerator could attain significant improvement in the mechanical and flexural performance.

Predicted of hydration heat and compressive strength of limestone cement mortar with different type of superplasticizer

  • Didouche, Zahia;Ezziane, Karim;Kadri, El-Hadj
    • Advances in concrete construction
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    • v.6 no.6
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    • pp.659-677
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    • 2018
  • The use of some superplasticizers in the production of mortar or concrete influences the hydration kinetic and the amount of total heat. This results in a modification of some properties, namely mortar workability, mechanical strength and durability. Three superplasticizers were used; a polynaphthalenesulfonate (PNS), a melamine resin (PMS) and a polycarboxylate (PC). They have been incorporated into various amount in a standardized mortar based on limestone cement. The aim of this study was to evaluate the rheological, mechanical and Calorimeters properties of this mortar. This will select the most compatible product and more able to be used depending on the climate of the country and the cement used. The PNS is incompatible with this type of cement registering a decrease of strength but the PMS and the PC modify the kinetics of hydration with significant heat generation and improved mechanical strength. The measured heat flow is significantly influenced by the type and dosage of superplasticizer especially for low dosage. Hydration heat and compressive strength of the different mixtures can be evaluated by determining their ultimate values and ages to reach these values where the correlation coefficients are very satisfactory.

A Study on the Properties of Inter-Locking Block Using Blast-Furnace Slag Cement (고로슬래그 시멘트를 사용한 인터로킹 블록의 특성에 관한 연구)

  • 이상태;이대주;신병철;김진선;권상준;한천구
    • Proceedings of the Korea Concrete Institute Conference
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    • 1997.10a
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    • pp.203-206
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    • 1997
  • In this paper, the properties of Interlocking block contained blast furnace slag cement are compared with that with O.P.C.(ordinary portland cement) and are analyzed under various mix proportions and the dosage of AE agent. According to the experimental results, compressive strength and flexural strength of interlocking block with blast furnace slag cement are lower than that with OPC. Also the strength and the ratio of absorption decrease with higher dosage of AE agent. although interlocking block with OPC has better performance than that of blast furnace slag in the side of quality, it is worth while to use the blast furnace slag as materials of interlocking block considered the side of recycling of resources and economy.

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Influence of Over-Added AE Water Reducing Agent on Physical Properties of the Concrete (AE 감수제 과다첨가가 콘크리트의 물리적 특성에 미치는 영향)

  • Han, Cheon-Goo;Han, Min-Cheol;Lee, Dong-Gyu
    • Journal of the Korea Institute of Building Construction
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    • v.8 no.1
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    • pp.91-96
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    • 2008
  • This study is to investigate the influence of the over-added chemical agents, such as water reducing agent(WRA) and AE water reducing agent(AEWRA), on the physical properties of concrete to estimate the degree of damage due to over-added chemical agents. For the fresh concrete, slump and slump flow increased with the increase of WRA and AEWRA as expected. Material segregation phenomenon was observed with the over dosage of lignin based AEWRA about 4 times larger than recommended dosage. The over dosage of AE water reducing agent about 4 times larger than recommended dosage resulted in an increase of air contents remarkably. The set retardation occurred greatly with the increase of AEWRA and WRA. For the properties of the hardened concrete corresponding to the over dosage of AEWRA, it is found that compressive strength of over added AEWRA and WRA concrete are much smaller than those of base and recommended dosage concrete proportionally due to associated increasing air content.

The Execution and Estimation of Construction Cost of High Fluidity Concrete Applying Flowing Concrete Method (유동화공법에 의해 제조한 고유동 콘크리트의 시공 및 원가분석)

  • Han, Min-Cheol
    • Journal of the Korea Institute of Building Construction
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    • v.4 no.2
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    • pp.129-136
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    • 2004
  • High fluidity concrete(HFC) requires high dosage of superplasticizer to acquire sufficient fluidity, and high contents of fine powder and viscosity enhancing admixtures to resist segregation. The use of high amount of admixtures to make HFC at batcher plant in ready mixed concrete company is one of the reasons to raise the manufacturing cost of HFC. For this reason, new type of manufacturing method of HFC are described using both flowing concrete method and segregation reducing superplasticizer(SRS) in order to gain economical profit and offer the convenience for quality control.. As dosage of melamine based superplasticizer increases, it shows that fluidity and bleeding increase, while air contents and ratio of segregation resistance decrease. It also shows that addition of viscosity agent into superplasticizer reduce bleeding and improve segregation resistance of concrete. Dosage of AE agent into superplasticizer containing viscosity agent recovers loss of air contents during flowing procedure. Combination of proper contents of superplasticizer, viscosity agent and AE agent make possible to develope segregation reducing type superplasticizer. Compressive strength of high fluidity concrete applying flowing method with it is higher than that of base concrete. No differences of compressive strength between compacting methods are found. For the estimation of construction cost of high fluidity concreting using segregation reducing type superplasicizer, under same strength levels, although material cost of high fluidity concrete is somewhat higher than that of plain concrete due to segregation reducing type superplasticizer cost, labor cost and equipment cost of high fluidity concrete is cheaper than that of plain concrete. However, based on the strength differences, high fluidity concrete shows lower material cost, labor cost and equipment cost than that of plain concrete due to decreasing in size of member and re-bar caused by high strength development of concrete.

Determination of Optimum Dosage of Polymer by Zeta potential in the Wastewater Treatment (수처리 시 Zeta전위 측정에 의한 응집제 주입량 결정)

  • Cho, Jun-Hyung;Kang, Mee-Ran
    • Journal of Forest and Environmental Science
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    • v.22 no.1
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    • pp.27-31
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    • 2006
  • Sedimentation characteristics such as SS, COD removal efficiency of wastewater in the toilet paper mill using recycled paper were examined by zeta potential. Optimum dosage of coagulant were determined by turbidity, SS, COD and then equation for treatment efficiency was suggested. Mechanical strength of floc was determined by turbidity.

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An Experimental Study on the Analysis of Concrete Properties According to the Over-Dosage of AE Water-Reducing Agent (AE감수제 과잉투여에 따른 콘크리트 특성 분석에 관한 실험적 연구)

  • 김정기;한천구;반호용
    • Proceedings of the Korea Concrete Institute Conference
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    • 1991.04a
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    • pp.15-18
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    • 1991
  • This study is designed for analyze the concrete properties according to the over-dosage of AE water-reducing agent; is aimed to analyze the effect of slump, air content, compressive strength of concrete and for presenting the reference data on the practical use.

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