• Title/Summary/Keyword: Donggang

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Bisphosphonates for Osteoporosis in Nonmetastatic Prostate Cancer Patients Receiving Androgen-deprivation Therapy: A Systematic Review and Meta-analysis

  • Ding, Hui;Yang, Li;Du, Wan;Teng, Yang;Fu, Sheng-Jun;Tao, Yan;Lu, Jian-Zhong;Wang, Zhi-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.3337-3343
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    • 2013
  • This systematic review was conducted to assess the efficacy and safety of bisphosphonates for prevention and treatment of osteopenia or osteoporosis in men with non-metastatic prostate cancer receiving androgendeprivation therapy. We searched for randomised controlled trials (RCTs) of bisphosphonates compared with placebo from Pubmed, Embase, the Cochrane Library, and ISI - Science Citation Index. Meta-analyses of prespecified outcomes (bone mineral density, fractures, and adverse events) were performed using Review Manager. Ten RCTs with a total patient population of 1,017 were identified. There was generally more improvement in bone mineral density of the lumbar spine for patients who received bisphosphonate treatment than placebo or other medical treatment at 12 months (WMD 6.02,95%CI 5.39 to 6.65). Similar effects were also observed for total hip, trochanter or femoral neck bone mineral density. However, there was no significant reduction in fractures. Fever and gastrointestinal symptoms were the most common adverse events (10.4% vs. 1.2%; 0.10% vs. 0.03%). Currently, our meta-analysis suggested that oral and intravenous bisphosphonates caused a rapid increase in spine and hip or femoral BMD in non-metastatic prostate cancer patients receiving androgen-deprivation therapy. Fever and gastrointestinal symptoms were common with the use of bisphosphonates. These short-term trials (maximum of 12 months) did not show fracture reduction. In future, more efficient performance of higher quality, more rigorous, large sample, long-term randomised controlled trials (>12 months) are needed where outcomes are detailed.

Electrocatalytic Effect of Dioxygen Reduction at Glassy Carbon Electrode Modified with Schiff Base Co(II) Complexes (Schiff Base Co(II) 착물이 변성된 유리질 탄소전극에서 산소 환원의 전기촉매 효과)

  • Seong, Jeong-Sub;Chae, Hee-Nam;Choi, Yong-Kook
    • Analytical Science and Technology
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    • v.11 no.6
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    • pp.460-468
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    • 1998
  • Schiff base ligands such as $SOPDH_2$, $SNDH_2$, $EBNH_2$, and $PBNH_2$ and their Co(II) complexes such as [$Co(II)(SND)(H_2O)_2$], [$Co(II)(SOPD)(H_2O)_2$], [$Co(II)(EBN)(H_2O)$], and [$Co(II)(PBN)(H_2O)$] have been synthesized. The mole ratio of Shiff base ligand to cobalt(II) for the Co(II) complexes was found to be 1:1. Also these complexes have been configurated with hexa-coordination. Reduction of dioxygen was investigated by cyclic voltammetry at glassy carbon electrodes modified with Schiff base Co(II) complexes in 1 M KOH aqueous solution. At modified glassy carbon electrode with Schiff base Co(II) complexes, reduction peak current of oxygen was increased and peak potential was shifted to more positive direction compared to bare glassy carbon electrode. The electrokinetic parameters such as number of electron and exchange rate constant were calculated from the results of cyclic voltammogrms. The reduction of dioxygen at glassy carbon electrode has been $2e^-$ reaction pathway. Exchange rate constant at glassy carbon electrode modified with Co(II) complexes was increased 2~10 times compared to bare electrode.

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A Study on the Appropriate Manpower Estimation according to the Evaluation of the Blood Collection Workload of Medical Technologists (임상병리사의 채혈 업무량 평가에 따른 적정 인력 산정에 관한 연구)

  • Choi, Se Mook;Yang, Byoung Seon;Kim, Yoon Sik;Lim, Yong;Oh, Yeon Suk;Bae, Do Hee;Choi, Byong Ho
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.4
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    • pp.495-503
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    • 2019
  • This study explored the method of determining the appropriate size of the workforce according to the assessment of the workload of medical technologists (also called medical and clinical laboratory technologists, and medical and clinical laboratory scientists) in order to present a standard production model for the appropriate manpower in blood collection rooms. The eleven university hospitals selected for this study had between 600 and 2,000 beds. The 14-steps standard blood collection time was 4 minutes and 8 seconds for the outpatients aged between 20 to 60 years old (57%) except for children and the elderly (43%). Assuming that there were 8 hours per day for mechanically collecting blood, the maximum number of blood donations by one clinical laboratory scientist was analyzed to be 100 cases. In conclusion, it is appropriate to have fewer than 100 cases of daily blood collection by a medical technologist engaged in blood collection. Since the proper number of blood collection workers (100% of blood collection work)=the number of annual working days/(one day's work hours/time per case)×the number of working days per year, then the proper number of blood collection workers (one day's work hours)=the number of working days per year/100×the number of working days).

A Study on the Realistic Media Creator Curriculum Based on Drone Video

  • Kim, Gi-Weon
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.10
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    • pp.83-91
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    • 2021
  • In this paper, presents an efficient education method for training specialized edutainment SW education instructors and drone realistic media creators, not just training to acquire certificates through drone manipulation training. To this end, the NCS-based curriculum was derived. The developed curriculum includes the edutainment drone curriculum and the realistic media creator curriculum. Among them, core responsibilities were defined for the drone control curriculum and core tasks, knowledge, and attitudes were described for each. After that, a detailed curriculum for drone control was derived. In the realistic media creator curriculum, pilot education was conducted to actually produce advertisement videos to foster experts who can work directly in the industrial field. Finally, through holding an online conference in a metaverse environment, a virtual conference was operated to share and discuss media videos produced by trainees. After the end of education, the efficiency of this curriculum was proved through education satisfaction analysis for 46 education graduates. This paper presented a method to achieve internalization of SW education in non-face-to-face online education that our society must solve after post-COVID-19. In addition, an efficient educational method in a realistic media environment was suggested by showing a realistic media creator training curriculum, pilot programs, and metaverse conference management cases.

The association of vitamin D and urine microalbumin/creatinine and obesity in Korean adults (한국 여성에서 혈청 ferritin과 25-hydroxyvitamin D 및 대사 증후군의 관련성)

  • Choi, Jung-Hun;Kim, Sung-Gil;Eun, Sung-Jong;Song, Mi-Ok
    • Journal of the Health Care and Life Science
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    • v.9 no.1
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    • pp.161-167
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    • 2021
  • The present study was conducted to assess the association between serum ferritin and 25-hydroxyvitamin D [25(OH)D] and metabolic syndrome (MetS) in Korean women. The data of a total of 9,256 adults (4,196 premenopausal women and 4,340 postmenopausal women) aged ≥ 20 years from the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V) (2010-2012) were analyzed. The key study results were as follows: First, in women without MetS, after adjusting for related variables (age, smoking, alcohol consumption, regular exercise, SBP, DBP, WM, TC, TGs, HDL-C, FPG, Hb, Hct, and Fe), vitamin D status was positively associated with serum ferritin levels (premenopausal, p < 0.001; postmenopausal, p = 0.027). Second, in women with MetS, after adjusting for related variables, vitamin D status was not associated with serum ferritin levels (premenopausal, p = 0.739; postmenopausal, p = 0.278). In conclusions, vitamin D status was positively associated with serum ferritin levels in women without MetS but not in women with MetS.

Educational Needs of Primary Caregivers of Children with Intellectual Disability in Mongolia (몽골 지적장애아동 주양육자의 교육요구)

  • Kim, Jinhee;Park, Seo Jin;Lee, Eun Young
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.319-334
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    • 2019
  • This study was conducted to identify the caregiver's educational needs for health care of children with intellectual disability in Mongolia. Data were collected from 150 family caregivers of children with disability in Mongolia between September 30 and October 31, 2017. The questionnaire included a scale for health care education needs in the form of 10 categories, 35 items, 5-point Likert's type. The mean score of educational needs of the primary caregiver were $4.05{\pm}0.65$. The category of information and knowledge acquisition showed the highest score ($4.48{\pm}0.57$). There were statistically significant differences in educational needs of the caregiver according to monthly income (F=7.07, p<.001), presence of a secondary caregiver (t=-2.70, p=.008), other disabled children status (t=2.02, p=.046), occupation status of disabled child's mother (F=3.87, p=.023), and multiple handicaps of caring child (t=-2.60, p=.010). The findings on caregiver's educational needs in this study can help inform planning of caregiving support services for children with intellectual disability in Mongolia.

Effects of Clinical Practice Satisfaction on Major Satisfaction Based on the Survey of Satisfaction of Clinical Laboratory Science Students on Clinical Practice (임상실습에 대한 임상병리(학)과 학생들의 만족도 조사를 바탕으로 임상실습 만족이 전공 만족도에 미치는 영향)

  • Shin, Kyung A;Kim, Hyo Shin;Lee, Sun Kyung
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.2
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    • pp.252-259
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    • 2019
  • This study examined the satisfaction of clinical laboratory science students practiced in clinical practice. In addition, the satisfaction of clinical practice and the satisfaction of the clinical practicum affecting the major satisfaction were investigated. From February 20, 2019 to March 10, 2019, a questionnaire survey was conducted on clinical laboratory science students who performed clinical practice in eight weeks of 2018. A total of 344 people were selected for the final analysis data. The questionnaire was comprised of 46 items, which consisted of three items of the general characteristics and 43 items of the clinical practice satisfaction. The satisfaction level of the clinical practice evaluation part was lowest in average 3.88 points. Male students were more satisfied with clinical practice than female students. The satisfaction level was higher in the group with more than the average degree of satisfaction than the group with less than the average. The factors that affect the satisfaction of clinical practice and the degree of satisfaction with majors are the satisfaction with the clinical practice time and satisfaction with interpersonal relationships.

Factors affecting Person-Centered Care Competence for senior nursing students: Focused on King's dynamic interaction system model (고학년 간호대학생의 인간중심간호역량 영향요인: King의 역동적 상호작용 체계모형을 중심으로)

  • Cho, In Young;Yun, Ji Yeong;Kim, Hyojin
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.357-367
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    • 2021
  • We aimed to identify personal-interpersonal-social factors influencing Person-Centered Care Competence (PCCC) of senior grade nursing students based on King's dynamic interaction system model. The data were collected using online based questionnaires that contained items on ethical sensitivity, peer group care interaction, interpersonal competence, social support and PCCC. The participants were 242 4th grade nursing students who had undergone clinical practicum. The data were analyzed using descriptive statistics, T-test, ANOVA, Pearson's correlation coefficients, and Multiple regression analysis with the SPSS 26.0. In the multiple regression analysis, interpersonal competence(β=0.42, p<.001) and social support(β=0.29, p<.001) were statistically significant factors that explained 44.1% of PCCC(F=23.77, p<.001). This study is significant in that we identified the factors affecting the Person-centered Care competence based on King's conceptual framework. This study could provide basic data for the development of an intervention program to improve PCCC of senior nursing students.

The Effect of Multi-faceted Learning by Application Game-based Student Response System in Nursing Education : Focusing on Kahoot! (간호교육에서 게임기반 학생응답시스템을 적용한 다각적인 학습효과 : Kahoot!을 중심으로)

  • Kim, Yu-Jeong
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.4
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    • pp.255-265
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    • 2021
  • The purpose of this study was to examine the effects of Kahoot!(Game-based Student Response System) on nursing education. This study used an one group Pretest-posttest design. Participants were 179 nursing students from one D university located in Gwangju, Korea. The Kahoot!(Game-based Student Response System) was provided for 6 times. Data were collected between August 26 and October 25, 2019. The collected data was analyzed by descriptive statistics, paired t-test, pearson's correlation coefficient and stepwise multiple regression using IBM SPSS 21.0 program. The results showed that learning engagement(t=-6.257, p=.000) was significantly higher than levels before Kahoot!(Game-based Student Response System), critical thinking disposition(t=-2.163, p=.032) was significantly higher than levels before Kahoot!(Game-based Student Response System), problem solving ability(t=-3.032, p=.003) was significantly higher than levels before Kahoot!(Game-based Student Response System). Significant relationships were found among learning engagement(r=.375, p=.000), critical thinking disposition(r=.286, p=.000), problem solving ability(r=.291, p=.000) and learning satisfaction. The results of stepwise multiple regression indicates that learning engagement(β=.307, p=.000), problem solving ability(β=.158, p=.041) predicts 15.2% in learning satisfaction(F=16.905, p=.000). In conclusion, Kahoot!(Game-based Student Response System) is effective in improving learning engagement and problem solving ability to nursing education.

The Phenomenological Study on Work Experience of School-Based Occupational Therapists (학교 작업치료사의 근무 경험에 관한 현상학적 연구)

  • Bae, Wonjin;Jung, Nam-Hae
    • The Journal of Korean Academy of Sensory Integration
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    • v.20 no.2
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    • pp.46-55
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    • 2022
  • Objective : This study aimed to explore the meaning of work experience of school-based occupatioanl therapists. Methods : This study was a phenomenological study. The participants were 7 school-based occupational therapists, all of whom were female with working experience of 5 years. One-on-One interviews were conducted with them about their work experience as school-based occupational therapists, and additional interview details were confirmed by e-mail. The interviews were recorded with the consent of the subjects. The researcher listened to the recordings several times prior to transcribing and analyzed the interviews according to Colaizzi's research method. Results : A total of 2 themes and 10 sub-themes were derived. Challenges and hopes were drawn as themes. The challenges theme included sub-themes administrative work burden, restriction of physical environment, lack of awareness of teachers, unstable employment, and legal restrictions. There were sub-themes such as sense of mission for children, team members with the same goal, children who want school-based occupational therapy, teacher' satisfaction, and responsibility for the development of school-based occupational therapy. Conclusion : Institutional improvement and policy support for school-based occupational therapy should be prepared to provide qualitatively improved school-based occupational therapy for special education subjects.