• Journal of Korean Society of Coastal and Ocean Engineers
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• v.12 no.2
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• pp.70-80
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• 2000

Princeton Ocean Model (POM) is modified to construct a three-dimensional, semi-implicit hydro¬dynamic model with a wetting-and-drying scheme. The model employs semi-implicit treatment of the barotropic pressure gradient terms and the vertical mixing terms in the momentum equations, and the velocity divergence term in the vertically-integrated continuity equation. Such treatment removes the external mode and thus the mode splitting scheme in POM, allowing the semi-implicit model to use a larger time step. Applied to hypothetical systems, both the semi-implicit model and POM give nearly the same results. The semi-implicit model, however, runs approximately 4.4 times faster than POM showing its improved computational efficiency. Applied to a hypothetical system with intertidal flats, POM employing the mode splitting scheme produces noises at the intertidal flats, that propagate into the main channel resulting in unstable current velocities. Despite its larger time step, the semi-implicit model gives stable current velocities both at the intertidal flats and main channel. The semi-implicit model when applied to Kyeonggi Bay gives a good reproduction of the observed tides and tidal currents throughout the modeling domain, demonstrating its prototype applicability.

• Cross-Cultural Studies
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• v.44
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• pp.373-391
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• 2016

Since the 2000's, interest toward Africa in Korea has increased rapidly. Korea's interest in Africa began in the second half of the 1960's. However, this interest in the 1960's was motivated by political and diplomatic necessity at the time rather than the needs of indigenous groups in Africa. Korea had to oppose North Korea's diplomatic expansion in Africa to gain the support of international organizations like the United Nations. This interest in Africa motivated by diplomatic needs vanished quickly after the end of the cold war in the 1990's. Authentic Korean interest in Africa began to emerge in the 2000's. Korea's rising international status based on economic development led to a natural interest in Africa, which was the last frontier on earth. As a result, African studies in Korea increased significantly after 2010. The increase in the number of theses, articles and books was remarkable from 2010-2016, in comparison with 1957-2010. In spite of the increase in the quantity of thesis, articles, and books, the problem with Korea's African studies is above all, its preponderance. Over 75% of thesis and 70% of articles are concentrated in the domain of politics and economics. This reflects the fact that Korea's interest in Africa is based on short term political and economic interest, indicating that Korea's African studies did not deviate from the rudimentary phase in its quantity and quality. Another problem with Korea's African studies is the lack of integration of different types of research. African studies in Korea has three components, government funded research centers, university laboratories and individual researchers. The government funded research centers focus on the overview of African nations and their political and economic information. University laboratories mainly perform research on the theoretical aspects of politics, economics, human sciences and culture in Africa. Individual researchers are concerned with various categories. However, these three groups have failed to achieve a synergic effect on African studies in Korea and most of the research on Africa does not extend beyond each academic area. To overcome this problem, first of all, a live exchange may be necessary between domestic researchers.

• Molecules and Cells
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• v.41 no.12
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• pp.1008-1015
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• 2018

$I{\kappa}B$, a cytoplasmic inhibitor of nuclear factor-${\kappa}B$ ($NF-{\kappa}B$), is reportedly degraded via the proteasome. However, we recently found that long-term incubation with proteasome inhibitors (PIs) such as PS-341 or MG132 induces $I{\kappa}B{\alpha}$ degradation via an alternative pathway, lysosome, which results in $NF-{\kappa}B$ activation and confers resistance to PI-induced lung cancer cell death. To enhance the anti-cancer efficacy of PIs, elucidation of the regulatory mechanism of PI-induced $I{\kappa}B{\alpha}$ degradation is necessary. Here, we demonstrated that PI up-regulates nuclear factor (erythroid-derived 2)-like 2 (Nrf2) via both de novo protein synthesis and Kelch-like ECH-associated protein 1 (KEAP1) degradation, which is responsible for $I{\kappa}B{\alpha}$ degradation via macroautophagy activation. PIs increased the protein level of light chain 3B (LC3B, macroautophagy marker), but not lysosome-associated membrane protein 2a (Lamp2a, the receptor for chaperone-mediated autophagy) in NCI-H157 and A549 lung cancer cells. Pretreatment with macroautophagy inhibitor or knock-down of LC3B blocked PI-induced $I{\kappa}B{\alpha}$ degradation. PIs up-regulated Nrf2 by increasing its transcription and mediating degradation of KEAP1 (cytoplasmic inhibitor of Nrf2). Overexpression of dominant-negative Nrf2, which lacks an N-terminal transactivating domain, or knock-down of Nrf2 suppressed PI-induced LC3B protein expression and subsequent $I{\kappa}B{\alpha}$ degradation. Thus, blocking of the Nrf2 pathway enhanced PI-induced cell death. These findings suggest that Nrf2-driven induction of LC3B plays an essential role in PI-induced activation of the $I{\kappa}B$/$NF-{\kappa}B$ pathway, which attenuates the anti-tumor efficacy of PIs.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.347-356
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• 2019

Recently, the liberalization of industrial control systems has been accompanied by a major change in the structural paradigm of information systems in the public and public sectors, and potential cyber security problems in the future major infrastructure control systems that cannot respond to the level of security of existing information systems. To cope with this, a cyber security evaluation tool that can evaluate security vulnerability in three dimensions against various infrastructure control system environment is needed. However, a cyber security evaluation in the domestic environments does not have the concept of the current security status and satisfy settings of the infrastructure. Also, the most of items in that environments have had short-term inspection themselves which makes a limitation by a technical area. In order to overcome this problems, many researches are needed to apply CSET (Cyber Security Evaluation Tool) which is the US cyber security evaluation tool to the control environment of various domestic infrastructure. In this paper, first, we analyze methods to apply to the major domain through the analysis of various case studies on existing security assessement tools. Finally, we discuss future directions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.291-298
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• 2021

In this study, the future of countermobility capability is presented by analyzing the status of the countermobility obstacles focusing on the history of landmines and munitions. The conventional landmine was forbidden globally by the CCW and Ottawa Treaty because it caused civilian damage after the war. Because the inhumanity of those mines had been acknowledged, shatterable mines with a self-destruct (SD) function and M93 "HORNET" anti-tank munition with enhanced sensors have been fielded. In 2016, the Obama administration announced a policy that banned all antipersonnel landmines, leaving a considerable gap in the countermobility capability. To deal with these problems, the developments of "SAVO" and the SLEP program of Volcano mines were conducted. In the sense of a long-term approach, the countermobility obstacles, including mines, were chosen as fundamental forces for Multi-Domain Operations and were improved to Terrain Shaping Obstacles (TSO). TSO has improved sensors and mobility kill capabilities and features an enhanced remote control over each munition on the battlefield through a network established with satellite communication. The combined arms countermobility might be fully capable until 2050 if the TSO program can be completed successfully.

• The Southeast Asian review
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• v.28 no.4
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• pp.161-196
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• 2018

The major object of this study is to analyze the political development of Myanmar's civilian government on the concept of defective democracy, and to investigate the main actors who delayed or stymied political development and their interrelation. In doing so, this study suggests the tasks required for political development overcoming the current political structure and behavior. The civilian government, which was launched in 2016, failed to achieve positive political development by following the behavior of military authoritarianism in terms of exercise of power and decision making structure. On the perspective of the government, delegative democracy and domain democracy have been strengthening since one person has taken over all political power and hesitate to take horizontal accountability for each power organizations. The military, which is responsible for national defence and security seeks illiberal democracy and exclusive democracy, keeping on an undemocratic constitution by the military and Burman ethnocentrism. The reasons why defective democracy has been occurred are that the lack of a group to run a democratic institutions and the limitation of power structure that fails to adhere to the principle of civilian control to the military due to long-term military rule. Therefore, there is a need for military's come back to barracks and transform the power structure to democratic of the civilian government which is tamed an authoritarian order for the political development in Myanmar. In order to achieve this, this study concludes that setting up a empowered democratic government is required.

• Journal of Korea Entertainment Industry Association
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• v.15 no.1
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• pp.117-129
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• 2021

Nowadays, the trend of early childhood education has focused on finding educational activities to enhance quality of learning with integrative, learner-centered experience by combining each subject and domain. Pre-service early childhood teacher's music drama activity is a sort of integrated education including literature, instrumental music, play, art and movement that are included in the culture and art for preschoolers to help them understand role and value of the art and directly influence personality and creativity and motive to arouse interest in various learning directly. It's expected to see that development of creative teaching plan for the music drama using piano ensemble could support basic research in integrated educational activity in the teacher training course and also, activate the music drama activity. Research findings and suggestion are as follows. First, the music drama activities are systematically and step-by-step implemented according to the audience according to the cooperative learning and creative plans of pre-service early childhood teachers. Second, if understanding characteristics of casts in the music drama and assigning their roles efficiently, it enhances approach of pre-service early childhood teacher music drama activity and activate it. Third, making music in music drama activities can be composed and arranged to suit the musical literacy and level of pre-service early childhood teacher. Fourth, pre-service early childhood teachers could have integrated experience and evaluation efficiently in the short term to use as reference for the teaching plan and data for the music drama.

• Journal of Korea Water Resources Association
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• v.55 no.12
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• pp.991-998
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• 2022

The purpose of this study is to develop GPU (Graphics Processing Unit) acceleration technique for 2-dimensional model and to assess the effectiveness for high resolution flood simulation in wide area In this study, GPU acceleration technique was implemented in the G2D (Grid based 2-Dimensional land surface flood model) model, using implicit scheme and uniform square grid, by using CUDA. The technique was applied to flood simulation in Jinju-si. The spatial resolution of the simulation domain is 10 m × 10 m, and the number of cells to calculate is 5,090,611. Flood period by typhoon Mitag, December 2019, was simulated. Rainfall radar data was applied to source term and measured discharge of Namgang-Dam (Ilryu-moon) and measured stream flow of Jinju-si (Oksan-gyo) were applied to boundary conditions. From this study, 2-dimensional flood model could be implemented to reproduce the measured water level in Nam-gang (Riv.). The results of GPU acceleration technique showed more faster flood simulation than the serial and parallel simulation using CPU (Central Processing Unit). This study can contribute to the study of developing GPU acceleration technique for 2-dimensional flood model using implicit scheme and simulating land surface flood in wide area.

• Journal of Ginseng Research
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• v.33 no.2
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• pp.115-126
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• 2009

To evaluate the efficacy and safety of red ginseng on women's health-related quality of life (QOL) and sexual function. A randomized, double-blind, placebo-controlled, crossover clinical study was performed. The main efficacy was measured using the Female Sexual Function Index (FSFl) and the 36-Item Short-Form Health Survey (SF-36). Twenty-four healthy, married women aged 30-45 years with FSFl scores below 25 were randomly divided into two groups: the red-ginseng group (N=12) and the placebo group (N=12). During the first six-week period (Study 1), each group was given red ginseng or placebo twice a day. Before the start of the second six-week period (Study 2), a crossover design was chosen with a two-week break (washout period). Interchanging the two groups after the washout period, red ginseng and placebo were given to each group. The outcomes were measured before and after each six-week period. Overall, 23 participants completed the study. In Study 1, the changes relative to the baseline in the FSFl total score were 22.50% and 22.99% for red ginseng and placebo, respectively. In Study 2, the relative changes were 8.14% for red ginseng and 6.29% for placebo. The results showed a greater improving trend in Study 1 with respect to all of the participants' sexual functions, but no significant difference was found between the groups (P=0.9567). After taking red ginseng, all the participants exhibited an improving trend in the desire domain of FSFl, but no significant difference was shown. In the measurement of SF-36, no significant difference was likewise shown. After taking red ginseng, though, all the participants exhibited an improving trend in the physical functioning (PF) domain of SF-36, with no significant difference. Moreover, there was no significant adverse event related to red ginseng. The QOL and sexual function of the study participants in the red-ginseng group were mostly improved, but no statistically significant effect of red ginseng was shown. It is supposed that this result was partly due to the affirmative impression of red ginseng in Korea. Thus, it is anticipated that a long-term clinical trial will show a significant effect of red ginseng on the QOL and sexual function.

• Journal of the Korean earth science society
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• v.27 no.4
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• pp.390-400
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• 2006

The purpose of this study is to propose an improvement plan based on an analysis of the current earth science teacher education curriculum in the department of education in the four fields of teaching profession theory: student-teacher practice, subject lesson education, and subject content education. The following are the conclusions and suggestions of this study. In case of teaching profession theory, too much emphasis is put on pedagogical theory over practical issues, and a problem arises upon completion. Therefore, it is sugguest that teaching profession theory might be completed before subject lesson education to ensure more authentic subjects performing teaching profession. The current term for student-teacher training is too short to understand the whole school system. Current school system does not have any off-job training course or internship system. Therefore, student-teacher training term should be increased by at least $3{\sim}6$ months to play a vital role in the current system. The credit number of subject lesson education is too small compared with subject content education. Consequently, the credit number of subject lesson education should be increased, and more professor majored in subject lesson education should be recruited. Significant deviation between the content of subject content education and that of middle school grade exists, and there is also much difference in the ratio of subject according to university. To get rid of these problems, subject content education should be connected with subject lesson education and appropriate number of credit needs to be assigned to each subject domain.