• Journal of Veterinary Science
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• 제24권4호
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• pp.46.1-46.12
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• 2023

Background: Heartworm infection in dogs is caused by Dirofilaria immitis and common in shelter animals and outdoors dogs. Caval syndrome can develop with severe infection and physical heartworm removal is essential with heartworm burdens. In this study, we used an improved transvenous heartworm extraction brush, which was expected to cause less cardiovascular damage and allow easier manipulation. Objectives: This study aims to evaluate efficacy of this improved transvenous heartworm extraction brush. Methods: The brush was designed to improve upon the limitations of the previous brush-type devices. The brush was made of a polyvinyl chloride tube and threads of polyamides or polyglyconates. Metal material was inserted at the front tip for easy visualization under fluoroscopy. The eight dogs diagnosed with caval syndrome with large numbers of heartworms and pulmonary hypertension were used in this study. The removal procedure began with the dissection of the subcutaneous tissue around the right jugular vein. The device was inserted through the jugular vein. After insertion, the tube was rotated to catch the heartworms and extracted with the heartworms hanging on the threads. The procedure was repeated several times. Lastly, jugular vein and skin sutures were made. Adulticidal therapy was administered after heartworm removal. Results: The mean number of removed heartworms was 10.5 ± 4.24 and mean number of remaining heartworms was 0.63 ± 1.06. Total procedure time was 72.63 ± 51.36. Except for three cases, heartworms were not detected on ultrasonography after the procedure. No procedure-related side effects were observed within the 1- to 2-mon. Conclusions: An improved transvenous heartworm extraction brush is efficient for heartworm removal in dogs with caval syndrome.

• 한국환경과학회지
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• 제33권4호
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• pp.279-282
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• 2024

This study aimed to verify the results of emotional analysis with respect to canine behavior as reported in the existing animal behavior field based on the dog vestibular emotional reflex (VER) principle, and to evaluate humans and animals based on empathy gained through true communication rather than human-centered interpretation. A total of 200 canines were divided into non-daily and daily situation groups (n=100 each). To assess the psychological and emotional state of each group, these changes were applied to the principle of VER, and six measurement values were selected: positive emotion (balance and energy), negative emotion (tension/anxiety and stress), and body condition (inhibition and neuroticism). The results showed a statistically significant difference (p<0.05) in positive emotions, negative emotions, and body conditions between the two groups. In addition, balance, energy, tension/anxiety, inhibition, and neuroticism were higher in the non-daily situation group than in the daily situation group, with an exception for stress. Compared with the canine daily situation groups, canine in the non-daily situation groups instinctively observed their surroundings to cope with possible threats, had decreased concentration, and elevated vitals due to high-intensity anxiety. This can be perceived as a state of immediate reaction to possible situations/threats. In conclusion, it was confirmed through Vibra Image technology that canine instability mainly affects three factors: positive emotion, negative emotion, and physical condition.

• 한국임상수의학회지
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• 제41권2호
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• pp.79-87
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• 2024

The tarsus in dogs has a complex structure that makes its evaluation relatively challenging. Because an accurate diagnosis of the tarsus is difficult through basic examinations alone, imaging tests are essential. Previous studies have explored the anatomical and radiological features of the canine tarsus using several imaging modalities. However, the imaging utility of the tarsus across different modalities has not been thoroughly evaluated. This study aimed to visualize the tarsal structures using magnetic resonance imaging (MRI) and ultrasonography, compare their utility, and propose suitable imaging modalities and conditions for evaluating specific tarsal structures. Magnetic resonance imaging and ultrasound scans of the tarsus of four healthy dogs were performed, and two observers rated the utility of each image on a five-point scale. Although MRI is more beneficial for assessing the tarsal structures than ultrasound, ultrasound also appears clinically useful for evaluating the cranial tibialis muscle, deep digital flexor tendon, subcutaneous fat, joint space, and superficial digital flexor tendon. In addition, each structure of interest can be evaluated for optimal visibility using specific ultrasound sections, MRI sequences, and planes. In veterinary clinical practice, an initial assessment using ultrasound imaging with optimal visibility is required and if further evaluation is necessary, MRI examinations with optimal MRI sequences and planes can be performed.

• 한국가금학회지
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• 제51권2호
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• pp.39-45
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• 2024

본 연구를 통해 닭고기를 활용한 반려견 간식 제품에서 동애등에 유충 분말의 유용한 고단백, 저지방 기능성 식품소재로의 활용 가능성을 확인하였다. 조단백질의 함량은 동애등에 유충 분말을 더 많이 첨가할수록 증가하였으며, 조지방의 경우 대조구(control)에 비해 처리구에서 낮은 조지방 함량을 나타냈다. pH의 경우, 동애등에 유충 분말을 첨가한 모든 처리구가 대조구에 비해 높은 값을 나타내었다. 육색 측정 결과, 동애등에 유충 분말 첨가량이 증가할수록 명도는 감소하였고, 적색도는 증가하였다. 이는 동애등에 유충 분말이 지속 가능할 뿐만 아니라 단백질 공급원의 역할을 하는 새로운 식품 소재로써의 가능성을 고려할 때 중요한 의의를 가지며, 경제적 이점을 위해 닭고기 부산물을 활용했을 때 낮아지는 단백질 함량을 개선하는 데 효과적으로 이용될 수 있음을 보였다.

• 한국임상수의학회지
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• 제41권4호
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• pp.207-214
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• 2024

An adult castrated male dog was presented with persistent hematochezia. Digital rectal examination and endoscopy found multiple colorectal masses. Complete blood count and serum biochemical results were within the reference interval. Fine needle aspirate of the masses indicated a diagnosis of inflamed polyps with a primary differential of malignancy. Histopathologic examination using endoscopy-guided incisional biopsy of the masses revealed an inflamed neoplasm with ossification. A colectomy was performed to remove the tumor. Subsequent histopathologic examination of the surgically resected masses resulted in a diagnosis of colorectal carcinoma in situ (CiS) with immune infiltrates, which were subject to immunohistochemical and flow cytometric immunophenotyping. The immunohistochemistry confirmed intraepithelial CD3⁺ T cells within CiS. The flow cytometric analysis indicated tumor-infiltrating CD4⁺ T, CD8⁺ T, and CD11b⁺ myeloid subsets. The flow cytometric analysis of circulating and tumor-infiltrating leukocytes demonstrated a preferential expansion of CD25⁺FOXP3⁺ regulatory T cells within CiS. To the author's knowledge, this is the first report to show clinical evidence emphasizing the immunogenicity and immune-suppressive environment of canine colorectal CiS. Our case will be valuable in providing a rationale for basic research that dissects the immune environment for canine colorectal cancers for the future development of cancer immunotherapy.

• 한국임상수의학회지
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• 제35권4호
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• pp.126-129
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• 2018

This study was performed to describe the outcome of pars plana retinopexy with perfluoro-n-octane (PFO)-silicone oil (SiO) exchange in dogs with rhegmatogenous retinal detachment in Seoul National University Veterinary Medical Teaching Hospital (SNU VMTH) from 2014 to 2017. Nine eyes of 8 dogs were included in this study. Medical records including signalment, history, duration from onset of blindness to surgical intervention, pre-operative findings, duration from surgery to regaining vision, and post-operative complications were evaluated. No eyes were visual before surgery. Duration from onset of blindness to surgical intervention was 2-30 days (median 8 days); duration from surgery to regain vision was 1-14 days (median 6 days); follow-up time was 15-1088 days (median 69 days). Post-operative complications were divided as temporary vs permanent conditions. Temporary complications were corneal ulcer, uveitis, retinal haemorrhage, glaucoma, subconjunctival leakage of SiO, and vitreal haemorrhage. Permanent complications were anterior chamber migration of SiO, retinal degeneration, corneal degeneration, re-detachment, and cataract. Six of 9 eyes regained functional vision, five of which remained visual throughout the follow-up time while the other one lost vision after 3 months because of uveitic glaucoma. In conclusion, pars plana retinopexy with PFO-SiO exchange provided fair outcome in 66.7% cases described in this study.

• 한국수정란이식학회지
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• 제28권1호
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• pp.25-30
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• 2013

The aim of this study was to estimate of ovulation time and parturition day at the same time as breeding in small dog by vaginal cytology and to confirm the accuracy by comparing the expected parturition day and the real one. Characteristic features of vaginal cytology during the estrous cycle were the high proportion of large intermediate cell, superficial cell, anuclear cell and erythrocyte in proestrus, superficial cell and anuclear cell in estrus, parabasal cell, small intermediate cell, large intermediate cell and leukocyte in diestrus, parabasal cell and small intermediate in anestrus, respectively. When day 0 was the parturition day, the period of pregnancy is 67.45(64~75) days when the cornification index (CI) is over 90%. Also, on the basis of ovulation day, 63.65(59~66) days was confirmed, and 57.0(52~60) days was confirmed based on the first day of diestrus. There are the gap of 4 days between the day being over 90% in CI and ovulation day. On the basis of this, when expecting parturition day based on the day being over 90% in CI by vaginal cytology, 18.1% was produced in the same of the expected parturition day and the real one, 30.3% and 33.3% were produced in the gap of one day and two days, respectively so, the accuracy within two days was 81.7%. In addition, based on the first day of diestrus, it also was identified to 81.7% as the difference between the expected parturition day and the real one within 2 days. It demonstrated there are any difference between any expected parturition day by vaginal cytology. Thus on the basis of the day of being over 90% CI, it is fully thought to using clinically due to the possibility of prediction the parturition day at the same time as the determination of the proper time of the optimal mating time.

• 한국조경학회지
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• 제49권4호
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• pp.15-29
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• 2021

본 연구의 목적은 Google Maps에서 제공하는 장소에 대한 리뷰를 활용하여 실제로 공원을 방문한 이용자의 인식과 평가를 파악하는 것이다. 구글맵리뷰는 Social Network Service(SNS)를 통해 장소에 대한 인식과 평가에 관한 정보를 얻는 온라인 리뷰이며, 일반 리뷰어와 구글맵의 회원으로 등록된 지역 가이드의 관점에서 장소에 대한 이해를 볼 수 있는 서비스이다. 본 연구에서는 구글맵리뷰 분석이 공원 관리에 필요한 이용자들의 인식과 평가를 추출하는데 활용될 수 있는지를 살펴보고자 하였다. 서로 다른 공간특징과 시설을 가지는 3개의 공원(서울숲, 보라매공원, 올림픽공원)을 대상으로 파이썬을 활용한 웹 크롤링을 통해서 구글맵리뷰 내용을 수집하였다. 그리고 텍스트 분석을 통해 공원별 주요 키워드 분석과 네트워크 구조에 따른 특성을 분석하고, 이와 함께 구글맵리뷰에서 제공하는 별점 평갓값과 외국인 리뷰 데이터에 대한 분석도 수행했다. 연구 결과, 3개의 공원에서 공통으로 나타나는 특성으로는 이용목적으로 '산책', '자전거', '휴식', '피크닉'이 있었으며, 동반유형으로 '가족', '아이', '애견'이, 인프라로는 '놀이터', '산책로'가 있었다. 공원별 특색을 보면 서울숲은 자연을 기반으로 하는 야외활동이 많이 나타났고 반면, 주차공간 부족과 주말 혼잡은 공원 이용자에게 부정적인 영향을 미치고 있었다. 보라매공원은 수많은 활동을 제공하는 다양한 시설을 갖춘 도시공원의 모습을 가지고 있었다. 리뷰어들은 반려견을 동반하는 이용자 그룹과 그렇지 않은 다른 이용자 그룹 간의 갈등과 공원의 복잡함에 대한 부정적인 측면을 언급했다. 올림픽공원에는 대형 복합시설이 있으며, 커뮤니티, 문화예술공연과 같은 대규모 문화 이벤트가 많이 언급되었고, 레크리에이션 기능이 강조되었다. 구글맵리뷰는 공원에 대한 이용자의 전반적 경험과 이미지에 대한 특징을 파악하는 유용한 자료라고 할 수 있다. 또한, 다른 소셜미디어 데이터와 비교할 때 특히 구글맵리뷰는 공원에 대한 이용자 평갓값과 만족 및 불만족 요인을 이해할 수 있는 데이터를 제공한다.

• 한국임상수의학회지
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• 제28권4호
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• pp.452-456
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• 2011

5 year-old female Siberian husky which was 27 kg had presented with a recurrent rhinitis with chronic discharge and cough. A nasal foreign material had been suggested by a finding of a bone density ($0.3{\times}0.3$ cm) in the left nasal cavity on X-ray and CT-scanning. Soft tissue opacity in frontal sinus and nasal cavity was increased and foreign material was located beside turbinate bone in the left nasal. We found that there was the increase in the number of eosinophil and mast cell by the nasal cytology test. These results mentioned above indicated that the rhinitis by nasal foreign body was suspicious. We decided that the transfrontal rhinotomy could be the proper procedure to approach the material in this case. After rhinotomy, the foreign body and severe sticky discharge were removed. Drain was placed through the hole and into the frontal sinus and nasal cavity which were flushed two times a day for 7 days. The clinical signs such as cough and nasal discharge were shown to be improved in the every visiting for the re-check. On the $40^{th}$ day after surgery, we could confirm that the most of soft tissue density in the frontal sinus and nasal cavity was decreased by CT-scanning. However, foreign body was not identified by histological examination. For the treatment of chronic rhinitis caused by foreign body, the surgical method such as rhinotomy can be applied, when it is difficult to remove it in the guide of the nasal endoscope.

• 대한약리학회지
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• 제12권1호
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• pp.23-29
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• 1976

최근(最近) 현저한 심근수축증강작용(心筋收縮增强作用)이 알려져 있는 부자(附子) ${\ulcorner}$부타놀${\lrcorner}$ 분획의 작용기전(作用機轉)을 구명(究明)코저 하는 시도(試圖)의 일환으로 심근수축단백(心筋收縮蛋白)에 대한 직접적인 영향을 관찰하였다. 부자${\ulcorner}$부타놀${\lrcorner}$ 분획은 actomyosin ATPase 활성(活性)에 대하며 별(別) 영향을 미치지 않았으며 actin-myosin 상호결합(相互結合)에서 $Ca^{++}$과 유사한 역활을 나타내지도 못했다. 단 actomyosin의 superprecipitation에 대하여는 약간 촉진적(促進的)이었으나 이러한 작용은 actomyosin ATPase 활성(活性)의 증가를 동반치 못했다. 그러나 microsmal $Na^+-K^+$-activated ATPase 활성(活性)은 현저히 억제하였으며 이러한 현상은 부자(附子)${\ulcorner}$부타놀${\lrcorner}$ 분획이 $Ca^{++}$의 membrane transport에 영향을 미칠것으로 인정되는 사실로서 부자(附子)${\ulcorner}$부타놀${\lrcorner}$ 분획의 심근수축증강작용기전(心筋收縮增强作用機轉)의 일부는 근수축단백(筋收縮蛋白)에 대한 직접작용보다는 extracellular 또는 intracellular membrane에서의 $Ca^{++}$ 이동에 영향을 미쳐 세포내 유리 $Ca^{++}$농도를 증가시키는것이 간접적으로 심근수축(心筋收縮)을 촉진(促進)시킬 것으로 사료되었다.