• Journal of Biomedical Engineering Research
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• v.23 no.3
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• pp.227-233
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• 2002

The IME(implantable middle ear) system is Promising due to its ability to free from sound feedback and Produce a good sound quality and intelligibility with low distortion even if it is operated with high gain for severe hearing impaired. The differential electromagnetic vibration transducer. which was developed for using in IME system and has two small magnets attached the same Pole facing in the coil. is not influenced by environmental external magnetic field. Besides, it has high vibration efficiency and good frequency response characteristics. In this Paper, using acoustic model of the transducer and ear model of normal Person. the signal transfer characteristics of the IME system are analyzed and investigated From the differences of the characteristics between normal ear and the IME system, it is Possible that design of the IME system that have the signal transfer characteristics similar to normal person's ear.

• Journal of the Optical Society of Korea
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• v.18 no.5
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• pp.436-441
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• 2014

We have demonstrated an amplified wavelength-division multiplexed (WDM) passive optical network (PON) by using broadband light source (BLS) seeded optical sources and chirped fiber Bragg gratings (FBGs) based dispersion compensators. Chirped FBGs located at central office (CO) were fabricated and used as channel-by-channel dispersion compensators in order to mitigate the dispersion-induced distortion of both downstream and upstream signals. Owing to a low insertion loss of chirped FBG based dispersion compensator, the optical signal-to-noise ratio (OSNR) of the downstream signal could be improved to be ~28 dB. Thus, we re-confirmed that an error-free transmission of 1.25 Gb/s signals over a 100 km single-mode fiber (SMF) link could be achieved with a proposed amplified WDM-PON architecture. We have also evaluated the impact of various noises on the system's performance, and found that the low OSNR of the downstream signal would be a main limiting factor on the maximum reach of the proposed amplified WDM-PON architecture. From the measured ~13 dB improvement in OSNR of the downstream signal compared to our previously-proposed dispersion compensating module based scheme, we believe that the proposed architecture can accommodate a reach of longer than 100 km SMF link easily.

• Molecules and Cells
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• v.39 no.3
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• pp.211-216
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• 2016

CYP107W1 from Streptomyces avermitilis is a cytochrome P450 enzyme involved in the biosynthesis of macrolide oligomycin A. A previous study reported that CYP107W1 regioselectively hydroxylated C12 of oligomycin C to produce oligomycin A, and the crystal structure of ligand free CYP107W1 was determined. Here, we analyzed the structural properties of the CYP107W1-oligomycin A complex and characterized the functional role of the Trp178 residue in CYP107W1. The crystal structure of the CYP107W1 complex with oligomycin A was determined at a resolution of $2.6{\AA}$. Oligomycin A is bound in the substrate access channel on the upper side of the prosthetic heme mainly by hydrophobic interactions. In particular, the Trp178 residue in the active site intercalates into the large macrolide ring, thereby guiding the substrate into the correct binding orientation for a productive P450 reaction. A Trp178 to Gly mutation resulted in the distortion of binding titration spectra with oligomycin A, whereas binding spectra with azoles were not affected. The Gly178 mutant's catalytic turnover number for the 12-hydroxylation reaction of oligomycin C was highly reduced. These results indicate that Trp178, located in the open pocket of the active site, may be a critical residue for the productive binding conformation of large macrolide substrates.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.41 no.2
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• pp.99-108
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• 2004

This thesis deals a method to deliver more realistic sound by cancelling the cross-talk which is inherent to the 5.1 channel speaker system. The acoustical model for cross-talk cancellation is the free field model. This model minimizes distortion of sound. I used the bark scale sound quality compensation which based on psycho-acoustic. For the surround channels, band-limited sound quality compensation is performed in the frequency domain. I also performed the sound quality assessment test on the traditional 2 channel stereo and 5.1 channel system. This test is performed in the test chamber which satisfies the ITU-R specifications. I uses the IACC(Inter-Aural Cross-Correlation) to determine the preferences of the amateur and the golden ear experts to asses the trans-aural filter. According to the result from the proposed method, I got more the 38㏈ separation rates with the Dolby standard speaker array. The results on the diffusion by the subjective test with the experts shows 0.4 point increased then before.

• Journal of Dental Rehabilitation and Applied Science
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• v.32 no.3
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• pp.246-254
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• 2016

Nowadays, 3 dimentional (3D) printing, especially Direct Metal Laser Sintering (DMLS) system is used in dentistry. DMLS system has recently been introduced for fabrication metal framework for metal ceramic crowns to overcome the disadvantages of the casting method and computer aided design/computer aided manufacturing (CAD/CAM) milling system. DMLS system uses a high-temperature laser beam to selectively heat a substructure metal powder based on the CAD data with the framework design. A thin layer of the beamed area becomes fused, and the metal framework is completed by laminating these thin layers. Utilizing DMLS system to fabricate fixed prostheses is expected to achieve free-from shaping without mold and limitations from cutting tools, fabricate prostheses with complex geometry, prevent distortion and fabrication defects that inherent to conventional fabrication methods. The purpose of this case report is to demonstrate various fixed prostheses such as long span fixed prostheses, post to achieve satisfactory results in functional and esthetic aspects.

• The Bulletin of The Korean Astronomical Society
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• v.41 no.1
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• pp.38.2-38.2
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• 2016

The mapping of dark matter clustering from real to redshift spaces introduces the anisotropic property to the measured density power spectrum in redshift space, known as the Redshift Space Distortion (hereafter RSD) effect. The mapping formula is intrinsically non-linear, which is complicated by the higher order polynomials due to the indefinite cross correlations between the density and velocity fields, and the Finger-of-God (hereafter FoG) effect due to the randomness of the peculiar velocity field. Furthermore, the rigorous test of this mapping formula is contaminated by the unknown non-linearity of the density and velocity fields, including their auto- and cross-correlations, for calculating which our theoretical calculation breaks down beyond some scales. Whilst the full higher order polynomials remains unknown, the other systematics can be controlled consistently within the same order truncation in the expansion of the mapping formula, as shown in this paper. The systematic due to the unknown non-linear density and velocity fields is removed by separately measuring all terms in the expansion using simulations. The uncertainty caused by the velocity randomness is controlled by splitting the FoG term into two pieces, 1) the non-local FoG term being independent of the separation vector between two different points, and 2) the local FoG term appearing as an indefinite polynomials which is expanded in the same order as all other perturbative polynomials. Using 100 realizations of simulations, we find that the best fitted non-local FoG function is Gaussian, with only one scale-independent free parameter, and that our new mapping formulation accurately reproduces the observed power spectrum in redshift space at the smallest scales by far, up to k ~ 0.3 h/Mpc, considering the resolution of future experiments.

• Investigative Magnetic Resonance Imaging
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• v.20 no.4
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• pp.215-223
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• 2016

Purpose: The management of metal-induced field inhomogeneities is one of the major concerns of distortion-free magnetic resonance images near metallic implants. The recently proposed method called "Slice Encoding for Metal Artifact Correction (SEMAC)" is an effective spin echo pulse sequence of magnetic resonance imaging (MRI) near metallic implants. However, as SEMAC uses the noisy resolved data elements, SEMAC images can have a major problem for improving the signal-to-noise ratio (SNR) without compromising the correction of metal artifacts. To address that issue, this paper presents a novel reconstruction technique for providing an improvement of the SNR in SEMAC images without sacrificing the correction of metal artifacts. Materials and Methods: Low-rank approximation in each coil image is first performed to suppress the noise in the slice direction, because the signal is highly correlated between SEMAC-encoded slices. Secondly, SEMAC images are reconstructed by the best linear unbiased estimator (BLUE), also known as Gauss-Markov or weighted least squares. Noise levels and correlation in the receiver channels are considered for the sake of SNR optimization. To this end, since distorted excitation profiles are sparse, $l_1$ minimization performs well in recovering the sparse distorted excitation profiles and the sparse modeling of our approach offers excellent correction of metal-induced distortions. Results: Three images reconstructed using SEMAC, SEMAC with the conventional two-step noise reduction, and the proposed image denoising for metal MRI exploiting sparsity and low rank approximation algorithm were compared. The proposed algorithm outperformed two methods and produced 119% SNR better than SEMAC and 89% SNR better than SEMAC with the conventional two-step noise reduction. Conclusion: We successfully demonstrated that the proposed, novel algorithm for SEMAC, if compared with conventional de-noising methods, substantially improves SNR and reduces artifacts.

• Current Optics and Photonics
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• v.2 no.3
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• pp.241-249
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• 2018

We report a midinfrared dual-field-of-view (FOV) optical system design for an airborne electro-optical targeting system. To achieve miniaturization and weight reduction of the system, it has a common aperture and fore-optics for three different spectral wavelength bands: an electro-optic (EO) band ($0.6{\sim}0.9{\mu}m$), a midinfrared (IR) band ($3.6{\sim}4.9{\mu}m$), and a designation laser wavelength ($1.064{\mu}m$). It is free to steer the line of sight by rotating the pitch and roll axes. Our design co-aligns the roll axis, and the line of sight therefore has a fixed entrance pupil position for all optical paths, unlike previously reported dual-FOV designs, which dispenses with image coregistration that is otherwise required. The fore-optics is essentially an achromatized, collimated beam reducer for all bands. Following the fore-optics, the bands are split into the dual-FOV IR path and the EO/laser path by a beam splitter. The subsequent dual-FOV IR path design consists of a zoom lens group and a relay lens group. The IR path with the fore-optics provides two stepwise FOVs ($1.50^{\circ}{\times}1.20^{\circ}$ to $5.40^{\circ}{\times}4.32^{\circ}$), due to the insertion of two Si lenses into the zoom lens group. The IR optical system is designed in such a way that the location and f-number (f/5.3) of the cold stop internally provided by the IR detector are maintained when changing the zoom. The design also satisfies several important performance requirements, including an on-axis modulation transfer function (MTF) that exceeds 10% at the Nyquist frequency of the IR detector pitch, with distortion of less than 2%.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.42 no.3 s.303
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• pp.63-72
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• 2005

In this paper, we propose a deformation technique based on Radial Basis Function (RBF) and a blending technique combining the deformed facial component with the original face for a Virtual Aesthetic Surgery (VAS) system. The deformation technique needs the smoothness and the accuracy to deform the fluid facial components and also needs the locality not to affect or distort the rest of the facial components besides the deformation region. To satisfy these deformation characteristics, The VAS System computes the degree of deformation of lattice cells using RBF based on a Free-Form Deformation (FFD) model. The deformation error is compensated by the coefficients of mapping function, which is recursively solved by the Singular Value Decomposition (SVD) technique using SSE (Sum of Squared Error) between the deformed control points and target control points on base curves. The deformed facial component is blended with an original face using a blending ratio that is computed by the Euclidean distance transform. An experimental result shows that the proposed deformation and blending techniques are very efficient in terms of accuracy and distortion.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.4 s.304
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• pp.159-166
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• 2005

This thesis deals with a method to deliver more realistic sound by cancelling the cross-talk which is inherent to the 5.1 channel speaker system. First, the cross-talk cancellation method that eliminates cross-talks on the path from left speaker to right ear and from right speaker to left ear is explained. Then the application and replaying method using the cross-talk cancellation explained here is introduced. The acoustical model for cross-talk cancellation is the free field model This model minimizes distortion of sound. Many experts also make studies on this model. I used the bark scale sound quality compensation based on psycho-acoustic. For the surround channels, band-limited sound quality compensation is performed in the frequency domain.