• 한국동물위생학회지
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• 제38권3호
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• pp.199-203
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• 2015

An 8-year old intact female poodle was presented to clinics due to abdominal distension, anorexia, and labored breath associated with pleural effusion. Intra-operative findings revealed multiple neoplasm of the greater omentum, involving anterolateral abdominal wall, sterna surface in the pleural cavity and diaphragm. These masses were 0.1~0.5 cm in diameter and extended to ovaries, pancreas, and serosal surface of stomach. Microscopically, most neoplastic cells had oval nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. In deeper area, neoplastic acinus or glandular structures showed invaginated growth resembling adenocarcinoma. High mitotic figures were observed. By immunohistochemistry, the neoplastic cells were strong positive both cytokeratin and vimentin. The present case described for malignant mesothelioma in a dog. Our findings might be helpful for diagnosis and information and helped the clinics choose the treatment including chemotherapy such as cisplatin.

• 한국임상수의학회지
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• 제31권3호
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• pp.246-249
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• 2014

9살의 중성화하지 않은 암컷 시츄가 복통과 복부 팽만을 주증으로 내원했다. 보호자는 개가 태어난 이후로 발정과 관련한 출혈을 단 한번도 관찰하지 못 했다. 초음파 검사 상에서 분절된 생식기계의 확장이 관찰되었다. 생식기계의 종괴를 확인하고, 난소 자궁 질 적출술을 실시하였다. 육안적으로 관찰했을 때, 질은 확장되어 있었고 고형의 짙은 초록색의 물질로 차있었다. 수술 결과와 질조영술을 바탕으로하여 처녀막 잔존증으로 진단하였다. 수술 한달 후, 봉합한 부위와 질의 막혀있는 부분 사이에 잔존성 질축농증이 발생하였다. 잔존된 처녀막은 내시경으로 제거하고, 세척하였으나, 복막염과 패혈증이 발생으로 폐사하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권5호
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• pp.2383-2388
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• 2016

Background: The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) gene is a novel transformation suppressor gene linked to several malignancies. Objective: To analyze any association between RECK gene rs10814325 single-nucleotide polymorphism (SNP) and HCC susceptibility with various clinicopathological and laboratory data. Materials and Methods: RECK gene rs10814325 SNP was estimated, using real-time PCR, in 30 HCC patients on top of HCV infection, 30 HCV related cirrhotic patients and 30 healthy controls. Results: No special pattern of association could be detected on comparing the RECK gene rs10814325 genotypes(P=0.5), or alleles(P=0.49) among the studied groups. HCC patients with TT genotype had younger age (mean of $54.1{\pm}6.0$ years vs $60.6{\pm}10.2$ years for TC/CC genotypes, P=0.035). Abdominal distension was significantly greater in TT genotype patients (75% vs 30%for TC/CC genotypes, P=0.045). The TT genotype was present in 75% of patients with lymph node metastasis. Serum GGT levels were higher in TT genotype patients [80 (48.5-134.8) IU/L vs 40 (33-87.5) IU/L for TC/CCgenotypes], and lower limb edema was observed in 60% for TT vs 20% for TC/CCgenotypes, but both just failed to reach significance (p=0.05 and p=0.06 respectively). Conclusions: RECK gene rs10814325 T>C could not be considered a risk factor for HCC development on top of HCV, but may be related to the disease progression and metastasis.

• Clinical and Experimental Pediatrics
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• 제45권7호
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• pp.923-927
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• 2002

우연히 발견된 간비장 종대를 주소로 내원한 3세 여아에서 신낭종을 동반한 선천성 간섬유화증을 진단한 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제36권2호
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• pp.134-140
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• 2010

Synovial condromatosis of the temporomandibular joint (TMJ) is characterized by the presence of loose bodies (joint mices). It can be confused with temporomandibular disorder clinically, and be with chondrosarcoma histologically. The purpose of this clinical report was to review the clinical, radiological, arthroscopic findings, histological feature and the results of surgical treatment of TMJ synovial chondromatosis. Four patients presented with pain of TMJ and limited mouth opening. The dynamic magnetic resonance imaging (MRI) disclosed a characteristic morphologic changes and displacement of the meniscus with limited translation of the condyle head. Bone scans showed progressive resorptive changes with hot-uptake of the radioisotope. The synovial loose bodies in the joint spaces were removed and sent to pathology for diagnosis as the synovial chondromatosis. The follow-up examination with computed tomography (CT) and MRI revealed no evidence of recurrence and good in function until postoperative 18 months. Diagnostically, the distension of the lateral capsule and fluid findings in the joint on the MRI are very suggestive tool for this synovial chondromatosis, but they are not always detected on the preoperative MRI. Arthroscopic approaches are very useful to inspect the joint spaces and to remove the loose bodies without interruption of the whole synovial membranes.

• 동의생리병리학회지
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• 제18권6호
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• pp.1552-1557
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• 2004

According to Li Sizhen, Drinking a little makes heart health, spirit active and let be relieved of fatique. Also it hastens gastroenteric digestion. In result, the appetite is stimulated. So Good-wine is useful for well-being necessary to treat a disease much more. However if drink to excess, it will cause mental disorder, exhansted blood, Impairment of stomach. As a consequence of that. Essence of life is exhausted too. So phlegm forms, Fire is more active easily. [In compendium of Materica Medica], 120 classes of counteracting Alcohol Drugs find room in it. Like this, an abundance of data and investigation about Counteracting Alcohol Drugs provides to us a large of Medical materials, and is a guide in Developing and Using the herbal resources. [Lei Gong's Nature of drugs in Songs] says 'Wine have a effect that get out Extravasated Qi and get rid of Pathogen, Abdominal mass with distension and pain.< As it says, ancient doctors displayed remedical Value that promote Qi and Blood circulation as a power of wine. But others says, 'To drink a wine as a drinking water makes us so intemperate, lets us be so being unreasonable easily as to drink hard and hurt our body. (1)Drink with nutritive appetizer. (2) Drink with sitting down. (3)Drink slowly. (4)Do not drink a differ on wine that is not true who makes. (5)Go easy on the alcohol. If drink with this position. Never drink hard for hurting body. Therefore, Cao Tingdong lived in the qing dynasty says "A preventing as a medicine is not so good as a preventing as a temperate living and meal."

• 동의신경정신과학회지
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• 제3권1호
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• pp.91-106
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• 1992

The effectiveness, the safety and the usefulness of HPS-A(An Jung San with Chyag Yag Kam Cho Tang), herbal digestive, was examined on 32 patients complained digestive symptoms. This medicine was administered 1 package per 1 time 3 times per 1 day, during 2 weeks. From the examination of the improvemnt and the safety mainly by subjective symptoms, the usefulness was gained. The results were as follows ; 1. In the improvement rate of susbjective symptoms, high rate symptoms was gastric distension, anorexia, heart burn, gastric discomport, dyspepsia, acrid eructation, indigestion, nausea. 2. The improvment over moderate effective was 85.7% after 1 week 96.4% after 2 weeks. The 4 cases breaked medicine during experimental period were all over moderate offectiveness. 3. There weren't any cases complaind particular problem about safety except for 1 case complained mild pushing up of heat. There weren't also any side effect of medicine on common blood count, blood chemistry and urinalysis. 4. In the dicision of usefulness, 19cases(59.4%) were usefulnesss, 12cases(37.5%) were moderate usefulness, 1 case was uselessness(3.1%). So the cases over moderate usefulness were 31 and rate was 96.9%. 5. The usefulness rates according to physical features were all over 95.5% in sturdiness, middle feature and infirmity. So the rates were no relations with the features. 6. The usefulness rates over moderate usefulness according to total seriousness were all over 90% in high, middle, and mild cases. So the rates were no relations with the seriousness. Totally HPS-A was a medicine that was highly effective, safe and useful to patients complained various digestive symptomes.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제12권1호
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• pp.57-63
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• 2009

평소 복부 팽만을 보인 2세 남아가 내원 3일 전부터 간헐적인 구토를 동반하여 시행한 복부 방사선 사진에서 좌상복부에서 석회화 소견을 관찰하여 상부 위장관내시경과 복부 전산화 단층 사진을 시행하였다. 술 후 병리 검사에서 상당히 빈도가 드문 석회화 섬유 종양을 발견하였기에 보고하는 바이다.

• 한국임상수의학회지
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• 제31권2호
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• pp.112-116
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• 2014

2개월령 수컷 핏불테리어종 개 (체중 1.01 kg)가 심한 복부 팽만, 운동 불내성, 성장 지연, 노란 비루와 식욕부진을 주증으로 진료 의뢰 되었다. 영상 진단상에 비정상적인 막으로 분할된 확대된 우심방, 심한 수축기 폐동맥 제트 혈류 (최고혈류 5.66 m/s) 그리고 심방 중격에서의 우좌 단락혈류가 관찰되었다. 임상증상 및 진단학적 결과에 기초하여, 본 증례는 심한 폐동맥 협착과 우좌 단락의 난원공 개존증이 합병된 우측 삼중심방증으로 진단 되었다. 비안정적인 환자의 상태 때문에 수술적 혹은 중재적 치료는 시도되지 않았다. 그 개는 수혈, 산소공급 그리고 심장 관련 약물적 치료(예, 실데나필, 스피로노락톤, 에날라프릴)로 회복되었다.

• 한국임상수의학회지
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• 제30권1호
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• pp.53-56
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• 2013

10세령 중성화된 페키니즈 견이 배뇨장애와 복부 팽대와 혈뇨 증상으로 내원하였다. 복부 방사선 촬영에서 상복부의 난원형 연조직 종괴가 발견되었으며 초음파 검사에서 액이 차 있고 종괴가 있는 낭으로 확인되었다. 탐색적 개복술을 통해 직경 4 cm 크기의 낭성 구조를 발견하였으며 적갈색의 액성 물질과 벽에 붙어 있는 직경 1.5 cm 크기의 원형 종괴를 확인하고 수술적으로 제거하였다. 절개한 종괴의 날인 도말 표본에 대한 세포학적 검사 결과 여러가지 악성 조건을 만족하는 선암종 세포가 다수 관찰되었으며, 조직병리 검사에서 확진되었다. 환자는 수술 회복되어 퇴원하였으며 재발증상의 징후 없이 지내다가 술 후1년 후 증상이 재발되어 내원하였고 종괴가 재발되었음을 확인하고 종괴 제거를 위한 2차 수술을 실시하였다. 환자는 퇴원 후 2개월째에 다시 내원하였으며 종괴가 재발되고 폐 전이가 발생한 것을 확인할 수 있었다. 환자는 이후 3개월을 더 생존하다가 폐사하였다.