• BMB Reports
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• 제48권9호
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• pp.489-494
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• 2015

The in vitro antibody discovery technologies revolutionized the generation of target-specific antibodies that traditionally relied on the humoral response of immunized animals. An antibody library, a large collection of diverse, pre-constructed antibodies, can be rapidly screened using in vitro display technologies such as phage display. One of the keys to successful in vitro antibody discovery is the quality of the library diversity. Antibody diversity can be obtained either from natural B-cell sources or by the synthetic methods that combinatorially generate random nucleotide sequences. While the functionality of a natural antibody library depends largely upon the library size, various other factors can affect the quality of a synthetic antibody library, making the design and construction of synthetic antibody libraries complicated and challenging. In this review, we present various library designs and diversification methods for synthetic antibody library. From simple degenerate oligonucleotide synthesis to trinucleotide synthesis to physicochemically optimized library design, the synthetic approach is evolving beyond the simple emulation of natural antibodies, into a highly sophisticated method that is capable of producing high quality antibodies suitable for therapeutic, diagnostic, and other demanding applications. [BMB Reports 2015; 48(9): 489-494]

• 반도체디스플레이기술학회지
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• 제8권4호
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• pp.37-42
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• 2009

The performance of an OLED(organic luminescent emitting device) fabrication system strongly depends on the design of the evaporation cell-source. Trends in display sizes have hauled the enlargement of mother glass substrates. The enlargement of substrates requires the improvement and the enlargement of the effusion cell-source for OLED evaporation process. The deposited layers should be as uniform as possible, and therefore it is important to know the effusion profile of the molecules emitted from the cell-source. Conventional 2D DSMC algorithm cannot be used for simulating the new concept cell-source design, such as a linear source. This work concerns the development of 3D DSMC (direct simulation Monte Carlo) analysis for simulating the behavior of the evaporation cell-sources. In this paper, the 3D DSMC algorithm was developed and the film thickness profiles were obtained by the numerical analysis.

• 제어로봇시스템학회논문지
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• 제9권3호
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• pp.242-250
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• 2003

We propose the monitoring system scheme for the CPS/INS integrated navigation system. The design requirements of the monitoring system are suggested and the software scheme based on GUI is proposed. The proposed monitoring system consists of an I/O interface part, a navigation data display part, and a post-processing part. The I/O interface part is responsible for data communication between the monitoring system and a navigation computer unit. The navigation data display part provides various display methods to show the navigation data to user in real-time. The post-processing part collects the navigation data to analyze the performance of navigation system. The proposed monitoring system software was developed using the Visual C++ programming language and a van test was carried out to demonstrate the real-time operation of the monitoring system. The test result shows that the proposed monitoring system can be effectively applied to the CPS/INS integrated navigation system.

• Journal of Information Display
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• 제5권1호
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• pp.7-15
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• 2004

A highly simplified backlight unit mainly composed of diffractive grating in sub-micron order imprinted light-guide plate (LGP) is proposed for edge-lit backlight unit. Optical characteristics of the imprinted LGP are examined by RCWA and the performance is verified through Monte Carlo simulation. Results show that the diffraction efficiency, luminous flux and its uniformity over the area are significantly affected by the angle of incident ray. Consequently couples of design considerations are additionally proposed to enhance luminous flux. In terms of peak luminance and out-coupling luminous flux, the experimental results are agreed well with the performance simulation. Finally, compared with optical characteristics of conventional backlight unit, we could conclude that the proposed simplified backlight unit made of diffractive grating imprinted light-guide plate is a good substitute for the conventional backlight unit.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1997년도 하계학술대회 논문집 E
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• pp.1746-1748
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• 1997

The surface discharge type ac plasma display panel(ac PDP) is a flat display devices using gas discharge. In ac PDP, parallel electrodes covered with dielectric layer are on a substrates. The discharge current characteristics are affected by cell structure. In this study, the relationship between the principal design factor and discharge characteristics is discussed, based on experiment, and the current waveform is measured by voltage detector and storage O.S.C. as a parameter of design factor, e.g., electrode gap and width.

• Journal of the Optical Society of Korea
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• 제19권6호
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• pp.614-618
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• 2015

This paper described an off-axis head-mounted display system. It is composed of a 7-piece coaxial relay lens group and a freeform surface combiner. This configuration has a simple structure and a wide field of view (FOV). In this design, a freeform surface is chosen as the combiner, to simplify the structure and attain good image quality. We generated this freeform surface by considering both coordinates and normals of discrete data points. Moreover, we realize a coaxial structure in the relay lens group, which is compact and benefits from a loose tolerance requirement. The HMD system we finally realized has a 40° × 30° FOV and 15-mm exit pupil diameter.

• 한국CDE학회논문집
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• 제7권1호
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• pp.18-26
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• 2002

The suggested modular projection system can have flexible arrangements of screens. Modular and continuous arrangements of the display system enable us to modify the screen configuration easily, so that the system can be used in various applications. The image of each screen is calculated automatically by using window projection and the tracked position of the viewer. This system also uses the off-axis stereoscopic projection for the seamless stereoscopic edge blending of multiple connections of screens. The system has been successfully tested for the general navigation model and the CAU driving simulator with motion platform.

• 한국실내디자인학회:학술대회논문집
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• 한국실내디자인학회 2005년도 춘계학술발표대회 논문집
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• pp.159-163
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• 2005

The purpose of this study was to analyze the relationship between the product characteristics and spatial configuration in a retail store. This study utilized the analytical method of Space Syntax, and the software package used for the analysis was New-wave and Pesh. The qualitative study focused on the showroom of 'H INTERIOR', a leading furniture company in Korea, and examined the accessibility of the space. The result showed that the main accessible route was well established in the retail store, and more trendy and fashionable products were likely to be displayed in more accessible places. Also, the products in the selected showroom were arranged according to the pricing information, so that products with lower price were displayed in more accessible places. This study suggested that it be important to adequately and appropriately display the products in relation to the characteristics of products, and implied that the method of Space Syntax was useful to strategically evaluate the display in retail spaces.

• 한국정밀공학회지
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• 제17권11호
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• pp.49-54
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• 2000

A field emission display has spacers separating the emitting base and display face. The arrangement of the spacer is important for maintenance of required clearance, endurance of bending stresses, and efficient vacuum sealing. Topology optimization technique with material density was introduced to select the best position of the spacers from the available positions. The displacement and Von Mises stress distribution of the panels with optimal spacers were calculated by finite element method. Also the design guide for adding eliminating spacers was proposed.

• Current Optics and Photonics
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• 제5권6호
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• pp.660-671
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• 2021

We present a novel optical system for an augmented reality head-up display (AR HUD) with two virtual images at different conjugates by employing a confocal off-axis two-mirror and introducing the horopter circle. For a far virtual image with large asymmetrical aberrations, we initially obtain an off-axis two-mirror system corrected for these aberrations and compensated for the down angle by configuring its parameters to satisfy the confocal and Scheimpflug conditions, respectively. In addition, this system is designed to reduce the biocular parallax by matching Petzval surface into the longitudinal horopter circle in a near virtual image. This design approach enables us to easily balance the residual aberrations and biocular parallax when configuring the optical system with two different conjugates, which results in an AR HUD available for near and far virtual images together.