• Korean Journal of Psychosomatic Medicine
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• v.4 no.2
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• pp.277-285
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• 1996

Somatoform disorders do occur among children and adolescents. Among the seven disorders under the grouping of somatoform disorders of DSM-IV, three disorders, namely somatization disorder, pain disorder and conversion disorder are seen relatively more often than one can expect in childhood and adolescence. Pain disorders are more prevalent among children before adolescence, whereas conversion disorder and somatoform disorder are seen more often during adolescence and early adulthood. Diagnoses of somatofram disorders should not be made by the process of exclusion, but based on positive findings that positive evidence that normal functioning is possible and that a positive history of psychosocial stress and or intrapsychic conflict exists. Treatment strategy should be mindful of including collaboration with primary care health professionals and family therapy staff in addition to all the basic treatment modalities essential for the treatment of children and adolescents.

• Clinical and Experimental Pediatrics
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• v.50 no.8
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• pp.718-725
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• 2007

Sleep disorders are very common among pediatric patients. Its prevalence is between 10% and 45% in preschool- and school-aged children. However parents commonly do not concern about their children's sleeping habits and for many pediatricians, there is not part of the routine office visit about a childs sleep. Sleep disorders were classified by International Classification of Sleep Disorder (ICSD) as dyssomnias, parasomnias, sleep disorders associated with mental, neurologic, or other medical disorders, and proposed sleep disorders. There are lots of differences in the causes, manifestations, and managements of sleep disorders between children and adult. The sleep disorders in childhood may manifest themselves as bedtime resistance, refusal to go to bed at a parentally described time, sleep-onset delay, inability to fall asleep within a reasonable time, prolonged nighttime awakening, and inability to return to sleep without assistance after waking during the night, and so have wide-ranging influences on children's behavior, mood, school performance, and family life. It's very important for pediatrician to concern about the sleep disturbances in childhood and so the problems of sleep in children should be early detected and managed.

• Proceedings of the Safety Management and Science Conference
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• 2008.04a
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• pp.149-156
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• 2008

The main objective of this study is to find factors and typical characteristics on outbreak of musculoskeletal disorders in small sized companies which are located at eastern area in Kangwon-Do. Musculoskeletal disorders are becoming a serious problem in various industrial fields. Many researches have been focused on the analysis on outbreak of musculoskeletal disorders in order to reduce and prevent them. As a similar endeavor, this paper provides factor analysis on outbreak of musculoskeletal disorders. Questionnaire surveys regarding musculoskeletal disorders were conducted for the total number of 250 field workers. For the purpose of this study, seven independent variables(gender, age, career, housework, accident, trouble, and pain) are taken from questionnaires. The provided analysis result will be helpful as a starting point for root cause analysis and reduction of musculoskeletal disorders and also for establishment of safe work environments.

• Journal of Genetic Medicine
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• v.20 no.1
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• pp.15-24
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• 2023

Monogenic disorders are traditionally attributed to the presence of mutations in a single gene. However, recent advancements in genomics have revealed instances where the phenotypic expression of apparently monogenic disorders cannot be fully explained by mutations in a single gene alone. This review article aims to explore the emerging concept of digenic or oligogenic inheritance in seemingly monogenic disorders. We discuss the underlying mechanisms, clinical implications, and the challenges associated with deciphering the contribution of multiple genes in the development and manifestation of such disorders. We present relevant studies and highlight the importance of adopting a broader genetic approach in understanding the complex genetic architecture of these conditions.

• Journal of the Korean Society of School Health
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• v.18 no.1
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• pp.71-82
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• 2005

Purpose: This study was undertaken in order to examine relations of eating disorders, health locus of control of college women, and to determine factors affecting eating disorders of college women. Method: The subjects were 282 students at a university in Busan. The instrument used for this study was a questionnaire on general characteristics, eating disorders (24 items), health locus of control (11 items) and self-esteem (10 items). Data were analyzed using means, percentages, t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression with a SPSS WIN 11.0 program. Result: Depending on BMI, there was no obese subject, 62.0% of the subjects were underweight, and 37.9% were normal. Over 40% of the subjects perceived them to be overweight while 62.1% of the women were underweight as defined by BMI. The total mean score of anorexia was higher than bulimia nervosa. There were significant differences in eating disorders according to BMI, perceived view of appearance, body satisfaction, experienced weight-control, and predictors of weight control method. Eating disorders showed a significant negative correlation with health locus of control and self-esteem. Stepwise multiple regression analysis revealed that the most powerful predictor of eating disorders was BMI. Experienced weight control, health locus of control and self-esteem and body appearance had significant effects on eating disorders. These predictive variables of eating disorders explained 27% of variance. Conclusion: The result of this study showed that eating behaviors among college women developed into eating disorders or were seriously disturbed. Therefore, to prevent eating disorders, health education should be provided to college women in relation to eating behaviors for health management.

• Health Policy and Management
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• v.27 no.2
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• pp.177-185
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• 2017

Background: The mental problems of the elderly are at issue as a serious social phenomenon. The purpose of this study is to identify risk factors affecting the mood disorders of the elderly. Methods: The subjects were 1,779,236 aged ${\geq}65$ and participated in health screening. Dependent variable was mood disorders. Independent variables were consisted of community level (regional deprivation index and healthcare resources) and individual level (sex, age, insurance type, disability, smoking, alcohol, physical activity, body mass index, and healthcare utilization). Multilevel logistic regression was performed. Results: At the individual level, women, employed insured, severely disabled people, heavy alcohol drinkers, high-intensity physical activity, body mass index, and patients who had chronic disease and severe disease were significantly associated with mood disorders. As the age has increased, it has let increase of mood disorders. At the community level, as the regional deprivation index has increased by 1, mood disorders has been increased by 1.005 times. The intra-class coefficient was 7.04%. Conclusion: We found individual and community level factors are associated with mood disorders. Systematic approach is essential to reduce mood disorders.

• 대한상한금궤의학회지
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• v.4 no.1
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• pp.13-28
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• 2012

Objective : The purpose of this study is to suggest medical approach to musculoskeletal system disorders using the decoction of Sanghan-Geumgwe. We studied cases of Ling-Gui-Gan-Zao-Tang prescribed patients to evaluate the clinical efficacy in musculoskeletal system disorders Method : We devised medical approach of Sanghan-Geumgwe in musculoskeletal disorders as follows. First, we chose ryeon-je(攣劑) and soo-je(水劑) herb medicine, commonly used in musculoskeletal disorders. In the selected herb group, we designated ryeon-je(攣劑) to be first key herbs, Soo-Je(水劑) as the second key herb, and other herb groups as third key herb. In this sequential selection and exclusion process, herbs were chosen based upon yak-neung-hyo-seon (藥能效選). Combination of those selected herbs drew pre-prescription group, finally prescription were made by the prescription criteria. Results : Based on the medical approach of decoctions of Sanghan-Geumgwe, we chose Ling-Gui-Gan-Zao-Tang to treat many kinds of musculoskeletal system disorders. And we achieved higher results on treatment for musculoskeletal system disorders. Conclusions : The medical approch using the decoctions of Sanghan-Geumgwe is very useful in choosing accurate prescriptions for patients with musculoskeletal system disorders in clinic.

• Journal of Technologic Dentistry
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• v.39 no.3
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• pp.187-196
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• 2017

Purpose: The purpose of this study was to investigate the factors contributing to temporomandibular joint disorder symptoms. Methods: The survey was conducted from May 1 to June 10 2017 against college students(120 males and 123 females) in Daejeon and Gangwon who understood the purpose of this study and agreed to participate. Results: First, The most frequent symptom of temporomandibular joint disorders is noises from the joint (male 45%, female 61.8%), followed by headache or neck pain (male 25.8%, female 52.8%). There was shown a significant difference by gender in all items except for jaw dropping, poor alignment of teeth and trauma(p<0.05). Second, Looking into the correlation between stress and subjective symptoms of Temporomandibular joint disorders, The stress of Temporomandibular joint disorders showed more significant relation with realistic issues such as academic task, economic burden (e.g., treatment cost), future career, and life values rather than aspect of social relationship(p<0.01). Conclusion: As a result of analyzing variables to understand the influence of stress on temporomandibular joint disorders, the accumulated number of bad habits, stress and temporomandibular joint disorders showed a significantly positive correlation with one another (p<0.05). In other words, the higher the stress level the severe the temporomandibular joint disorders; the more the bad habits the severe the temporomandibular joint disorders;

• Biomolecules & Therapeutics
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• v.29 no.4
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• pp.353-364
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• 2021

The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the GI tract can lead to GI disorders. GI disorders are highly prevalent in the population and account for substantial morbidity, mortality, and healthcare utilization. GI disorders can be functional, or organic with structural changes. Functional GI disorders include functional dyspepsia and irritable bowel syndrome. Organic GI disorders include inflammation of the GI tract due to chronic infection, drugs, trauma, and other causes. Recent studies have highlighted a new explanatory mechanism for GI disorders. It has been suggested that autophagy, an intracellular homeostatic mechanism, also plays an important role in the pathogenesis of GI disorders. Autophagy has three primary forms: macroautophagy, microautophagy, and chaperone-mediated autophagy. It may affect intestinal homeostasis, host defense against intestinal pathogens, regulation of the gut microbiota, and innate and adaptive immunity. Drugs targeting autophagy could, therefore, have therapeutic potential for treating GI disorders. In this review, we provide an overview of current understanding regarding the evidence for autophagy in GI diseases and updates on potential treatments, including drugs and complementary and alternative medicines.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.185-192
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• 2017

Objectives : The aims of present study was to investigate clinical characteristics of male patients with eating disorders. Methods : The present study included 32 male patients with eating disorders and 75 female patients with eating disorders, recruited from an eating disorders specialized clinic in a university hospital, Seoul, Korea. We compared clinical characteristics of eating disorders and comorbid conditions of depression and anxiety between men and women with eating disorders. Correlations between eating disorders psychopathology in men with eating disorders and their weight suppression(WS) were investigated. Results : There was no difference in age at presentation, age of onset, illness duration, and body mass index at presentation between genders. Male patients with eating disorders had higher rates of premorbid overweight or obesity than female patients with eating disorders had. WS in the male patients was associated with the severity of their eating disorders. Conclusions : The present study provides grounds for improved understanding for clinical features of eating disorders in males.