• 대한두개안면성형외과학회지
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• 제14권1호
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• pp.50-52
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• 2013

Povidone-iodine (PVP-I, Betadine) has many advantages as a disinfectant solution for preoperative preparations, especially for oral surgery. It is widely used because of its low toxicity and excellent bactericidal effect. The authors report a case of pneumonia secondary due to the aspiration of PVP-I, which was used as an oral disinfectant. We present a case of aspiration pneumonia that resulted from the careless use of PVP-I during preoperative preparation. The patient was a 10-month-old female scheduled for elective surgery to correct a complete cleft of secondary palate. During the preparation of the oral cavity for that cleft palate patient, PVP-I was incidentally aspirated to the airway. The lung resistance was noted with positive pressure and pneumonic infiltration on chest radiograph was seen. The operation was postponed and the patient underwent respiratory care. Three months later, elective palatoplasty under general anesthesia was performed without complication. Based on the experiences of this case, the authors advise that throat-packing should be placed before oral preparation to prevent serious pulmonary complications.

• 한국융합학회논문지
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• 제10권10호
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• pp.27-31
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• 2019

본 연구의 목적은 교내 실습실의 유니트체어 수관의 바이오필름을 채취하여 미생물을 분석하고, 기존적인 물빼기방법과 소독제를 사용하는 방법을 적용하여 미생물 수의 변화를 비교하고자 실시하였다. 교내의 수관으로부터 샘플을 채취한 후 R2A배지를 이용하여 배양하였다. 미생물 동정을 거쳐 분리된 미생물의 균종을 분석하였다. 물빼기에 대한 미생물 감소를 확인하기 위해 30초, 60초, 120초 간격으로 샘플을 채취하였고, 소독제의 효과를 확인하기 위해 소독 후 샘플을 채취하였다. 이렇게 수거된 샘플을 통해 얻은 미생물의 정량적 비교는 SPSS 프로그램을 이용하였다. 결과에서 동정된 균주는 총 8개로 나타났으며 대부분 그람음성인 Sphingomonas 계열로 확인되었다. 60초의 물빼기를 통해 미생물의 수가 급감하는 것을 확인하였고, 소독 즉시 미생물은 검출되지 않았다. 본 연구에서 제시된 방법과 결과를 바탕으로 소홀하게 관리될 수 있는 유니트체어의 수관을 관리함으로써 교차 감염을 예방하고 체계적인 관리가 가능할 것이다.

• 한국산업보건학회지
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• 제29권1호
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• pp.13-20
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• 2019

Objective: This study was performed to propose a domestic occupational exposure limit(OEL) following a health hazard assessment, calculation of a non-carcinogenicity reference concentration worker($RfC_{worker}$) value, and examination of international agencies' exposure limits. It also recommends legal management within the Occupational Safety and Health Act for PHMG-Phosphate(CAS No. 89697-78-9), It is a humidifier disinfectant that generated many lung injuries. Methods: We have investigated the recommendation or guidelines of foreign OEL for PHMG-Phosphate and the actual state of legal management in Korea. To examine the procedures and methods for recommendation OEL. Toxicological hazard and health hazard classifications were examined and a non-carcinogenicity $RfC_{worker}$ value was calculated for PHMG-Phosphate. An OEL and the necessity of legal management were recommended as well. Results and Conclusions: The OEL for PHMG-Phosphate is recommended to be $0.01mg/m^3$. The recommended OEL is close to 10 times the RfCworker value of $0.000833mg/m^3$ calculated from the chemical dose-response hazard assessment, which is a 2017 study. The CMIT/MIT(3:1) mixture, which was a social issue as a humidifier disinfectant substance, was also exposed to the same ratio in March 2018, establish the OEL. It is recommended to establish OEL for PHMG-Phosphate to prevent worker health hazards and for chemical safety management.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.175.1-175.1
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• 2016

In recent, tract infections such as atopic dermatitis, allergic rhinitis and a respiratory disease are increasing, giving rise to the atmospheric pollution, inflow of micro-size dust and side effect of humidifier disinfectant. In this context, the environment-friendly technology is required to eliminate airborne pathogens. We propose solution of the previous problems, making use of Radical Mist Generator (RMG). Existing technologies of air purification using a gas discharge produce harmful substances such as ozone, NOx, etc. However, the RMG uses a pure water as a plasma forming material. The RMG sprays the water mist, which contains reactive radicals to sterilize microorganisms. RMG is comprised of a power supply, plasma electrodes and a nozzle. In order to analyze the electrical characteristic and concentrations of reactive radicals, we employ an oscilloscope and a titration method. To test the sterilization effect of RMG, we used E.coli. We confirmed that E.coli was killed over 90%. Eventually, we expect that RMG can be promising tool for a purified system.

• 한국식품위생안전성학회지
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• 제7권2호
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• pp.99-106
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• 1992

To prevent food-poisoning outbreaks by Vibrio vulnificus the antimicrobial efficacy of grapefruit seed extract (GFSE) was examined. Minimal inhibitory concentration (in vitro) for the microorganism was found to be 50∼100 ppm. Transmission electron micrographs of Vibrio vulnificus showed the biocidal action of this natural antimicrobial agent would be related to specific respiratory effect coupled with the destruction of permeable function of microbial cell membrane. After Anguilla japonica GFSE-injected to the body was incubated in the seawater contaminated by Vibrio vulnifiucs the fish meats were taken up, mixed with control diet and used as a diet in the feeding experiment. In this experiment the effect of GFSE treated with fish muscle on body weight, protein efficiency ratio, serum enzymes and serum blood components of broiler chicks was investigated. It is proved from this study that there is neither Vibriosis nor toxicity associated with GFSE itself an fish meats treated with it when it is injected to the fish body at a level of 250 ppm or less.

• 상하수도학회지
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• 제23권6호
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• pp.763-768
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• 2009

Ozone is a strong oxidant and a powerful disinfectant. In general, it has been used in drinking water treatment during last 100years. Ozone dissolution features are defined by the two categories of ozone contactors, bubble-diffuser and sidestream ozone contactor. Currently, sidestream-injection systems are gaining in popularity but operating cost might be slightly higher. Sidestream ozone system dissolve ozone into a sidestream flow via an injection setup or in the main process flow stream in some sidestream arrangements. The sidestream flow is subsequently mixed with the main process flow stream, which is directed to a reation tank or pipeline for oxidation and disinfection reactions. The purpose of this study is to suggest optimal operating pressure, to figure out the static-mixer effect and to understand the microbubble characteristics of ozone to improve dissolution efficiency.

• 한국환경보건학회지
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• 제32권3호
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• pp.215-221
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• 2006

This study investigated the inactivation of the total coliform, an indicator organism in chlorine dioxide, in order to assess the optimal disinfection procedure for drinking water treatment and distribution systems. This research focus on a number of factors, including the dosage of disinfectant, contact time, pH, temperature and DOC. Water samples were taken from the outlet of a settling basin at a conventional surface water treatment system. As the pH increased in the range of pH 6-9, the bactericidal effects of disinfectants decreased. Changes in levels of pH did not significantly after the disinfection effect of chlorine dioxide for total coliform. With an increase in temperature, there was a subsequent increase in the bactericidal effects of disinfectants. Thus, it is evident that a decrease in temperature will higher the CT values required to inactivate coliform for during the winter. DOC addition can also reduce total coliform inactivation. DOC is the most significant variable in total coliform inactivation with chlorine dioxide.

• 미생물학회지
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• 제17권2호
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• pp.65-71
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• 1979

On studying of microbes and appearance frequency which are floating around dwelling space and life environments in Seoul area, the results are summarized as follows ; 1. 1931 strains of 29 bacteria are isolated in dwelling spaces, Among them, there are Staphylococcus aureus, S. anthracis which are pathogenic to human beings. 2. In fungi, 76 strains of 13 species are isolated. That of highest frequency is confirmed to be Aspergillus which is pathogens of Aspergillosis (one of a group of diseases of animals and human being caused by various species of Aspergillus). The places, where the number of kinds and the frequency of appearances have been observed highest, are coffee shops, lunch counters and office rooms, while factory districts are of far lower level than expected. 3. 0.1% $HgCl_2$, Leasking oil, and Telephone disinfectant were better than any other in fungicidal effect.

• Journal of Microbiology and Biotechnology
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• 제11권3호
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• pp.418-422
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• 2001

Growth inhibition of Compylobacter jejuni ATCC 33291 was observed in the presence of various preservatives at various temperatures. The addition of ethanol (0.5% to 5%), hydrogen peroxide (0.05%), acetic acid (1%), propionic acid, benzoic acid, and sorbic acid showed strong antibacterial activities against C. jejuni at pH 5.5 or 6.5. The addition of 1% acetic acid and lactic acid were most effective at $42{\circ}C, followed by $25{\circ}C$ and $4{\circ}C$. This indicated that the inhibitory effect was temperature dependent. In the chicken model system, the practical death rate of C. jejuni in the FBP-media with 1% acetic temperatures ($4{\circ}$C$, $25{\circ}$C, and $42{\circ}$). Therefore, precaution has to be taken in the use of organic acids as a disinfectant in the chicken slaughterhouse.

• 한국환경보건학회지
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• 제32권4호
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• pp.282-291
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• 2006

This study investigated the inactivation of the total coliform, an indicator organism in chlorine and chlorine in order to control microbial regrowth for water distribution systems and select an appropriate disinfection strategy for drinking water systems. The disinfection effects of chlorine and chlorine dioxide with regard to the dosage of disinfectant, contact time and DOC was investigated experimentally. In spite of the consistency of chlorine residuals at approximately 0.2 mg/l, bacteria regrowth was detected in the distribution system and it was confirmed by the scanning electron microscope results. The influence of organic carbon change on the killing effect of chlorine dioxide was strong.