• Title/Summary/Keyword: Disease severity

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Effects of Aerobic Exercise on Disease Severity and Walking Ability in Patients with Parkinson's Disease

  • Bang, Dae-Hyouk;Noh, Hyeon-Jeong
    • The Journal of Korean Physical Therapy
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    • v.28 no.4
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    • pp.227-231
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    • 2016
  • Purpose: This study was conducted to explore the effects of aerobic exercise on the severity of disease and walking ability in patients with Parkinson's disease. Methods: Twelve patients with Parkinson's disease participated in the study. Participants were randomly assigned to either an aerobic exercise group (n=6) or a self-exercise group (n=6). All participants underwent treadmill training for 30 minutes. In addition, the experimental group (aerobic exercise group) and control group (self-exercise group) participated in a 30 minutes exercise program. In both groups, exercise was performed five times a week for four weeks. Outcome including disease severity (Unified Parkinson's Disease Rating Scale) and walking ability (10 m walking speed test, 6 minutes walking test, timed up-and-go test) were measured at baseline and after 4-weeks. Results: Significant differences in disease severity and walking ability were observed between the pre- and post-exercise groups (p<0.05). The improvement of disease severity and walking endurance was significantly higher in the experimental group than in the control group (p<0.05). Conclusion: These findings demonstrate that aerobic exercise is effective at improving disease severity and walking endurance in patients with Parkinson's disease.

Development of Leaf Spot (Myrothecium roridum) and Dispersal of Inoculum in Mulberry (Morus spp.)

  • Kumar, P.M.Pratheesh;Pal, S.C.;Qadri, S.M.H.;Gangwar, S.K.;Saratchandra, B.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.6 no.2
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    • pp.163-169
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    • 2003
  • Studies were conducted on the effect of pruning time, host age, conidial dispersal and weather parameters on the incidence and severity of mulberry leaf spot (Myrothecium roridum). The disease severity (%) increased with increase in shoot age irrespective of pruning date. Maximum disease severity was observed in plants pruned during first week of April and minimum disease severity in plants pruned during first week of March. Significant (P < 0.01) influence of date of pruning, shoot age and their interaction was observed on severity of the disease. Apparent infection rate (r) was significantly higher during the plant growth period from day 48 to day 55. Average apparent yale was higher in plants pruned during first week of April and least in plants pruned during first week of July. The disease infection was negatively correlated to distance from the inoculum source. Leaf spot severity (%) was influenced by weather parameters. Multiple regression analysis revealed contribution of various combinations of weather parameters on the disease severity. Linear prediction model $(Y = -81.803+1.176x_2+0.765x_3) with significant $R^2$ was developed for prediction of the disease under natural epiphytotic condition.

Factors Influencing Development and Severity of Grey Leaf Spot of Mulberry (Morus spp.)

  • Kumar, Punathil Meethal Pratheesh;Qadri, Syed Mashayak Hussaini;Pal, Susil Chandra
    • International Journal of Industrial Entomology and Biomaterials
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    • v.22 no.1
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    • pp.11-15
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    • 2011
  • Impact of pruning date, shoot age and weather parameters on the severity and development of grey leaf spot (Pseudocercospora mori) of mulberry was studied. The disease severity (%) increased with increase in shoot age irrespective of pruning date. Maximum disease severity was observed in plants pruned during second week of October and minimum in plants pruned during last week of December. Significant (P<0.05) influence of date of pruning, shoot age and their interaction was observed on the severity of the disease. Apparent infection rate (r) was significantly higher during plant growth period from day-48 to day-55. Average apparent rate was higher in plants pruned during first week of September and least in plants pruned during third and fourth week of December. Multiple regression analysis revealed contribution of various combinations of weather parameters on the disease severity. A linear prediction model [$Y=66.05+(-1.39)x_1+(-0.219)x_4$] with significant $R^2$ was developed for prediction of the disease under natural epiphytotic condition.

Dispersal of Xanthomonas axonopodis pv. citri, the Causal Bacterium of Citrus Canker, on Unshiu Orange.

  • Myung, Inn-Shik;Nam, Ki-Woong;Kwon, Hyeog-Mo
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.121.1-121
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    • 2003
  • Dispersal of Xanthomonas axonopodis pv. citri, causing citrus bacterial canker disease on Unshiu orange was investigated at previously infested plots at Seogwipo in Jeju island of Korea. The bacterial pathogen overwintered in lesions started to multiply at tate May, and disease firstly observed one month after detection of phage from lesions. The disease gradually increased, however, it dispersed non-directionally to nearby plants from inoculum sources. Diseased plants were aggregated to form a cluster throughout the experiment. Population dynamics of phage on symtomless leaf surface and the disease severity were compared in the nursery, Increase of phage population on symptomless leaf surface preceded one month to that of the disease severity Population of phage increased constantly from late July to October, however, the disease severity decreased from late August to late October. It was assumed that the decrease of disease severity might be due to disease-induced defoliation.

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Relationship between Pain-related Variables and Extent of Heart Disease (심장질환자에서 흉부 통증 특성과 심장질환 정도와의 관계)

  • Kim, In-Ja
    • The Korean Journal of Rehabilitation Nursing
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    • v.6 no.1
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    • pp.7-13
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    • 2003
  • Purpose: To identify the essential characteristics of pain which nurse have to obtain for patients with chest pain, 92 patients who were admitted in medical units to take intensive tests for heart disease were investigated cross-sectionally. Method: Duration, severity, stress, anxiety, perceived severity, number of painful area, number of accompanying symptoms, triggering activity, and pattern were included as the characteristics of pain. Ejection fraction of left ventricle and number of involved area detected by ultrasonography and number of diseased coronary artery detected by cardiac catheterization were assessed as the variables of heart disease extent. Result: Severity of pain was found to be correlated with all three variables of heart disease extent. Perceived severity and number of accompanying symptoms were correlated with two of them. Anxiety, number of painful area and pattern were related with the number of involved area. Conclusion: Pain severity reported by patients is found to be the most important variable to be obtained from patient. Variables such as perceived severity, number of accompanying symptoms, anxiety, number of painful area and pattern also have to be carefully assessed to anticipate the extent of heart disease.

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Remote Health Monitoring of Parkinson's Disease Severity Using Signomial Regression Model (파킨슨병 원격 진단을 위한 Signomial 회귀 모형)

  • Jeong, Young-Seon;Lee, Chung-Mok;Kim, Nor-Man;Lee, Kyung-Sik
    • IE interfaces
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    • v.23 no.4
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    • pp.365-371
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    • 2010
  • In this study, we propose a novel remote health monitoring system to accurately predict Parkinson's disease severity using a signomial regression method. In order to characterize the Parkinson's disease severity, sixteen biomedical voice measurements associated with symptoms of the Parkinson's disease, are used to develop the telemonitoring model for early detection of the Parkinson's disease. The proposed approach could be utilized for not only prediction purposes, but also interpretation purposes in practice, providing an explicit description of the resulting function in the original input space. Compared to the accuracy performance with the existing methods, the proposed algorithm produces less error rate for predicting Parkinson's disease severity.

Evaluating the Association between Anemia and the Severity of Liver Disease in Children with Cirrhosis: A Cross-Sectional Study from 2015 to 2020

  • Seyed Mohsen Dehghani;Iraj Shahramian;Hamideh Salehi;Leila Kasraian;Maryam Ataollahi;Masoud Tahani
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.27 no.5
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    • pp.286-297
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    • 2024
  • Purpose: Liver cirrhosis is a major cause of hospital admission and mortality among children. Understanding the factors that influence disease severity is essential for preventing and reducing mortality. This study explored the association between hemoglobin levels and liver disease severity in children with cirrhosis. Methods: This cross-sectional study included 326 children with cirrhosis admitted to Namazi Teaching Hospital between 2015 and 2020. Clinical data, Child-Turcotte-Pugh (CTP) scores, and pediatric end-stage liver disease/model for end-stage liver disease (PELD/MELD) scores were collected to assess disease severity. Anemia was defined based on age, sex, and hemoglobin levels. Results: Among the children with cirrhosis, 275 (84.4%) were anemic, with a mean age of 5.4±4.8 years. The overall mean hemoglobin level was 9.2±2.1 g/dL. A significant inverse correlation was observed between hemoglobin levels and CTP and PELD/MELD scores in children with anemia (p<0.001). Moreover, lower hemoglobin levels were associated with more higher CTP classes (p<0.001). Conclusion: According to the data analysis, a significant correlation was observed between hemoglobin level and the severity of liver disease, and hemoglobin level decreased with increasing severity of liver disease. According to CTP class, the mean hemoglobin level decreased progressively as the disease progressed. A comparison of the mean CTP scores between children with and those without anemia revealed that those with anemia had more severe disease than those without anemia.

Disease Prevalence, Parent's Educational Needs, and Disease Management according to Severity of Respiratory Infections in Early Childhood (영유아 호흡기 감염 중증도에 따른 이환실태, 부모의 교육요구 및 관리수행정도)

  • Han, Hye-Yul;Park, Sun-Jung;Lee, Myung Nam;Kang, Kyung-Ah
    • Child Health Nursing Research
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    • v.21 no.3
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    • pp.227-235
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    • 2015
  • Purpose: The purpose of this study was to investigate disease prevalence, parent's educational needs, and disease management according to severity of respiratory infections in early childhood. Methods: Participants for this study were 173 mothers whose child was admitted to I university hospital in Seoul and whose child was an infant or toddler. Data were collected from December, 17, 2014 to February, 15, 2015 using self-report structured questionnaires. Data were analyzed using IBM/SPSS 21.0 program. Results: There were significant differences in the severity of respiratory infection according to neonatal admission due to dyspnea, feeding type, atopic dermatitis in the infant or allergic disease in father and siblings. Parent's educational needs for the severe respiratory infection group were higher than for the non-severe group. Parent's disease management for the severe respiratory infection group was lower than the non-severe group. Conclusion: As important care factors in neonatal admissions include dyspnea, cow milk feeding, eczema, family history of allergies, parent's educational needs and disease management, they should be considered when caring for young children with respiratory infections and their parents.

Ecological Factors Influencing Severity of Cashew Fusarium Wilt Disease in Tanzania

  • Lilai, Stanslaus A.;Kapinga, Fortunus A.;Nene, Wilson A.;Mbasa, William V.;Tibuhwa, Donatha D.
    • Research in Plant Disease
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    • v.27 no.2
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    • pp.49-60
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    • 2021
  • Cashew (Anacardium occidentale L.) is an important cash crop in Tanzania as a source of income to cashew growers and provides foreign exchange for the country. Despite its significance, the crop is threatened by fast spreading disease known as cashew Fusarium wilt caused by Fusarium oxysporum. Field assessment and laboratory tests were conducted to determine incidences of the disease, severity, ecological factors that influence them and explored the pathogen host specificity in six cashew growing districts. The results revealed significant (P<0.001) variation of disease incidences and severity among the studied districts. The results further revealed that there is both positive and negative correlation between the incidence and severity of the disease versus the evaluated ecological factors. The soil pH, soil temperature, air temperature, and relative humidity depicted positive correlation of disease incidence and severity versus ecological factors at ρ=0.50 and ρ=0.60, ρ=0.20 and ρ=0.94, ρ=0.11 and ρ=0.812, ρ=0.05 and ρ=0.771 respectively while nitrogen, phosphorus, and carbon depicted negative correlations at ρ=-0.22 and ρ=-0.58, ρ=-0.15 and ρ=-0.94, ρ=-0.19 and ρ=-0.12 respectively. In terms of host range, none of the weed species was found to be a carrier of Fusarium pathogen implying that it is host specific or semi selective. The results revealed that the tested ecological parameters favor the growth and development of Fusarium pathogen. Thus, management of the disease requires nutrients replenishment and soil shading as essential components in developing appropriate strategies for the control and prevention of further spread of the disease.

Effects of Sawdust and Urea Application on Disease Severity and Streptomyces scabiei Pathogen Dynamics (톱밥 및 요소의 투입이 감자 더뎅이병 병원균(Streptomyces scabiei) 및 감자 더뎅이병 이병도 지수에 미치는 영향)

  • Bak Gyeryeong;Lee Jeong-Tae;Jee Sam-nyu
    • Journal of Environmental Science International
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    • v.32 no.11
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    • pp.777-788
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    • 2023
  • Potato common scab disease is caused by pathogens belonging to Streptomyces spp. and results in a serious yield loss worldwide. Despite decades of research aimed at disease management, a definitive control method remains undiscovered. This study aims to explore the correlation between the C/N ratio and urea application with potato common scab pathogen dynamics and disease severity. We applied sawdust with a high C/N ratio and urea into the soil prior to potato cropping, both in pot and field experiments. Disease severity assessments and quantification of the TxtB gene were conducted at the harvest stage. Furthermore, culture experiments were performed to assess the direct impact of urea on the pathogen. Our findings revealed that higher disease severity was correlated with a high C/N ratio application and pathogenic gene quantity. Urea exhibited a direct influence on S. scabiei activity, reducing the disease severity in pot experiments. However, the effects of urea application on disease suppression in the conductive field were inconclusive. Although the results of urea application experiments displayed inconsistencies between pot and field trials, urea worked as the control to suppress S. scabiei activity. Further investigations are needed under various field conditions to confirm these findings.