• Title/Summary/Keyword: Disease research

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Systematic Review of the Effects of Blood Flow Exercise for Health-care Promotion: A Focus on Korean Domestic Research (헬스케어 증진을 위한 혈류조절 가압 운동의 효과에 대한 체계적 문헌고찰 ; 국내 연구 중심으로)

  • Seo, Tae-Hwa;Kim, Dong-Won
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.447-454
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    • 2020
  • The purpose of this study was to determine the clinical effects of blood flow regulation exercise for improving patients' health care and its usefulness as a rehabilitation model for various diseases by analyzing and examining the existing literature. A literature review of Korean academic journals published over a 10-year period, from 2010 to 2019, was conducted using words such as "blood flow regulation," "blood flow restriction," "low-intensity exercise," and "Kaatsu." Kaatsu is a blood flow regulation exercise developed in 1966 by Dr. Yoshiaki Sato of Japan. It is an efficient and effective exercise method that uses blood flow regulation bands that increase the secretion of growth hormones to develop muscles within a short time, improves blood circulation and metabolism to prevent and improve adult diseases, shortens the rehabilitation period, and improves cardiovascular function. The study participants consisted of 10 patients, of whom four were elderly, four had obesity, one was a stroke patient, and one was a trauma patient. The results of this study show that the blood flow regulation exercise, which is a low-intensity exercise, has the same effect as high-intensity exercise, which supports the evidence that it is a highly efficient exercise method for muscle development and rehabilitation of the elderly, adolescents, and patients with injuries who have difficulty in general exercising. For future studies, further reviews are necessary to verify the effectiveness of the exercise method according to blood flow regulation site and type of disease.

The Incidence and risk factors of delirium in elderly surgical patients (외과계 병동 노인 수술 환자의 섬망 발생률과 위험요인)

  • Lee, Eun Ju;Jang, Mi;Kim, Myung Hwa;Yun, Hye Jun;Kim, Eun Mi;Chung, Young In;Kim, Bo Kyung;Im, Eun Su;Hong, Kyoung Soon
    • Journal of Korean Clinical Nursing Research
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    • v.28 no.2
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    • pp.137-145
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    • 2022
  • Purpose: This retrospective chart review study was conducted to examine the frequency of delirium and to identify the risk factors of delirium in elderly surgical patients. Methods: The subjects of this study were 394 patients aged 65 years or older who underwent surgery. The diagnosis of delirium was based on the nursing assessment records with scores from the day of surgery to the 4th day after surgery. The collected data were analyzed by binary logistic regression analysis. Results: The incidence of delirium was 4.3%, and delirium occurred most frequently on the first day of surgery and lasted for 2.16 days on average. Of delirium patients, 76.5% underwent gastrointestinal surgery, and the most common delirium pattern was disorientation. In terms of the characteristics of the subjects, the occurrence of delirium was statistically different by age (𝝌2=10.79, p=.005), systemic-specific disease (𝝌2=9.63, p=.047), use of delirium-inducing drug(benzodiazepine) before surgery (𝝌2=15.90, p<.001), walking ability before surgery (𝝌2=7.65, p=.006), history of delirium (𝝌2=35.92, p<.001), and emergency surgery (𝝌2=16.40, p<.001). As risk factors of delirium, gastrointestinal surgery was found to increase the risk of delirium by 12.57 times (95% CI=2.45~64.46, p=.002), and the use of benzodiazepines before surgery was shown to increase delirium by 10.07 times (95% CI=2.21~45.87, p=.003). Conclusion: It is necessary for nurses to actively evaluate delirium using screening tools for early detection and prevention of delirium in elderly surgical patients with delirium risk factors.

A Study on Deriving Key Management Factors for the Prevention of COVID-19 in Construction Sites (건설현장 코로나 바이러스 예방을 위한 중점관리요소 도출에 관한 연구)

  • Shin, Eun Kyoung;Eom, Yong Been;Kim, Dae Young
    • Journal of the Korea Institute of Building Construction
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    • v.22 no.1
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    • pp.91-102
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    • 2022
  • Many industries are being severely damaged by COVID-19, a respiratory infection that has recently been prevalent around the world. In particular, for workers in the construction industry, it is impossible to work from home, and if an outbreak on a construction site is confirmed, it can lead to great damage. Accordingly, the government has drafted 「Guidelines for Response to Construction Sites for Prevention and Spread of COVID-19」. In addition, domestic and foreign research about COVID-19 in the field of construction sites is being actively conducted. However, Korea has lacked studies on the effectiveness of the countermeasures in place at construction sites, or that reflect the opinions of construction site workers. Therefore, this study conducted a survey of construction site workers by dividing the construction of the COVID-19 quarantine management system and response plan into on-site management and social management. Through the AHP/IPA analysis, it was found that among social management, 'infectious disease management system and cooperation system with related institutions' and 'reduction of working hours' are areas with high importance but low satisfaction. After that, the causes of the two items were analyzed and related countermeasures were suggested. The results of this study will be able to contribute to the improvement of the quarantine management system and response plan at construction sites, and to minimize the damage to the construction industry related to COVID-19.

The Effect of Knowledge related to COVID-19, Performance of Infection Control and Job stress of Nurse in Emergency Department on the Nursing Performance (응급실 간호사의 COVID-19 관련 지식, 감염관리수행 및 직무스트레스가 간호업무수행에 미치는 영향)

  • Kwon, Mi Kyung;Je, Nam Joo
    • The Journal of the Convergence on Culture Technology
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    • v.8 no.6
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    • pp.107-119
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    • 2022
  • This study was a descriptive research study to identify the effects of related knowledge to COVID-19, infection control performance, and job stress in emergency department nurses due to COVID-19 on nursing performance, to improve emergency department nurses' ability to cope with emerging infectious diseases and to prepare basic data for effective nursing work. This study was collected data from August, 10 until September, 10, 2021, for 165 emergency department nurses in 26 hospitals, which were located in G province and designated as regional emergency medical institutions, and total 150 copies were finally analyzed. Data were analyzed using descriptive statistics, t-test, ANOVA, correlation, and multiple regression. As a result of analyzing the variables affecting the subject's nursing job performance by multiple regression using the hierarchical selection method, the higher the infection control performance and the higher the job stress, the more higher the nursing job performance, and the explanatory power was 18.4%. The study results showed that infection control performance, job stress, and non-shift work had an effect on nursing performance. It was thought that various plans to protect them, reduced tasks to efficiently perform and the nursing ability to cope with emerging infectious disease should be prepared to improve and reduce the job stress of emergency department nurses.

Research on Oral Health Knowledge and Oral Health Behavior of Chinese Domestic Students

  • Chung, Kyung-Yi
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.11
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    • pp.173-179
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    • 2022
  • This study was conducted to provide basic data for the development of oral health education programs by examining oral health knowledge and oral health behaviors, and by identifying factors affecting oral health knowledge and scaling experience of Chinese domestic students. From March to May, a self-reported questionnaire was administered to 194 in the G area. The data were analyzed frequency analysis and independent t-test, multiple regression analysis, logistic regression analysis by using SPSS/WIN 26.0 program. The overall average of oral health knowledge was 13.83 out of 24, and knowledge of periodontal disease and scaling was the highest at 3.75, and knowledge of oral hygiene products was the lowest at 1.38. Oral health knowledge was significantly higher in those who had scaling experience for the past year, brushed teeth for more than 3 minutes at a time, used oral hygiene products, and had oral health education experience. As a result of multiple regression analysis, oral health education experience was the most important factor on oral health knowledge. As a result of logistic regression analysis, oral health knowledge was the most influential factor on scaling experience. It is necessary to expand education on the importance of oral care and actively introduce oral health management program for Chinese domestic students.

The Effects of Ecklonia stolonifera Extracts on Improvement of Hepatic Function: a Double-Blind, Randomized, Placebo-Controlled Clinical Study (곰피추출물의 간기능 개선 효과 평가를 위한 12주, 무작위배정, 이중맹검, 위약-대조 인체적용시험)

  • Kim, Junghee;Kim, Eun Jin;Kang, Dahye;Kim, Hyung-Bin;Jang, Jae Young;Om, Ae-Son;Kim, Jongwook
    • Journal of Food Hygiene and Safety
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    • v.37 no.3
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    • pp.198-205
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    • 2022
  • Hepatic diseases are divided into two types: alcoholic and non-alcoholic. Non-alcoholic liver injury finally induces fatty liver and damages liver function. Many studies have demonstrated that Ecklonia stolonifera has antioxidative, anti-inflammatory, and hepatoprotective activities. We conducted a 12-week double-blind, placebo-controlled, randomized trial to examine the efficacy of E. stolonifera extracts (ESE) on biochemical markers of hepatic function. Sixty-five subjects with mild or moderate liver injuries were randomly allocated to receive either 420 mg/d of ESE or a placebo for 12 weeks. Fifty-five participants completed the trial. No significant adverse events were observed among the subjects during the study. The primary end points were changes in plasma levels of aspartate transaminase (AST), alanine transaminase (ALT), and γ-glutamyltransferase (γ-GT). The secondary end points were changes in lipid profile levels, including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL), and low-density lipoprotein cholesterol (LDL). Compared with the baseline, AST and ALT levels decreased significantly in the ESE group compared to those in the placebo group (P<0.001). In addition, γ-GT levels in the ESE group were significantly lower than those in the placebo group (P=0.016). There were no differences in the TC, TG, HDL, and LDL levels between groups. In conclusion, ESE consumption for 12 weeks improved liver parameters in subjects with liver injury. Regular consumption of ESE could maintain liver health in individuals at risk of hepatic damage.

2020 Dietary Reference Intakes of water for Koreans: establishment and future tasks (2020 한국인 수분 섭취기준 설정과 앞으로의 과제)

  • Lee, Jae Hyun;Kim, Sun Hyo
    • Journal of Nutrition and Health
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    • v.55 no.4
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    • pp.419-429
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    • 2022
  • Water accounts for the largest proportion of body weight and is an essential element for the physiological functioning of the human body. According to 2013-2017 Korea National Health and Nutrition Examination Survey (KNHANES) data, the average water intake of Koreans was 2,167.3 mL/day and 62% of them did not meet the Dietary Reference Intakes for Koreans (KDRIs) for water. However, the consumption of beverages is continuously increasing. KDRIs sets the adequate intake (AI) for water, but tolerable upper intake level (UL) and chronic disease risk reduction intake (CDRR) are not provided. Compared to 2015, the AI of total water from both food and fluids in the 2020 KDRIs slightly increased or decreased according to age. The AI for children 1-2 years old, boys 6-8 years and 9-11 years old, and girls 6-8 years old decreased by 100 mL/day, while that of boys 12-14 years old increased by 100 mL/day. The AI of total water was the sum of the water intake from food and fluids reported by the KNHANES, with an extra milk intake of 200 mL/day. Therefore, it is not appropriate to use the AI of total water intakes for the reference of beverage intakes. It is preferable to consume water or milk rather than beverages containing sugar and others including caffeine, sodium, etc. when drinking fluid water. We suggest the following improvements in the future KDRIs for water: improving the adequacy of the water content ratio of Korean conventional foods, supplementing the fluid water intake survey, reflecting the current water intake status by life cycle, setting KDRIs for water for the elderly considering the physiological changes, health status and dietary habits, and promotion of research on the relationship between water intake and health for Koreans.

A Systematic Review of Mobile Health Applications Using Self-Acupressure (자가혈위지압을 활용한 모바일 의료 어플에 대한 체계적 문헌고찰)

  • Seokyung Park;Johyun Lee;Ga-Young Jung;Celine Jang;Sang-Ho Kim
    • Korean Journal of Acupuncture
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    • v.40 no.1
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    • pp.1-12
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    • 2023
  • Objectives : This study aims to provide information regarding the status and quality of mobile applications (MAs) using self-acupressure by performing a systematic review. Methods : We conducted comprehensive searching on five international databases and two app markets from inception to July 31, 2022 to identify MAs using self-acupressure. We analyzed the characteristics of each MA regarding the name of the MA, registered app markets, target symptoms, developers, the year and country of development, cost, target age, media function, and expertise. We assessed the quality of each MA using Mobile Application Rating Scale (MARS). Results : We identified a total of 30 MAs using self-acupressure (25 MAs from the app market and 6 MAs from clinical studies, with 1 MA in common). 17 out of 24 MAs from the app market provided self-acupressure regimens for various symptoms and the others provided regimens for specific symptoms such as memory, anxiety, depression, asthma, allergy, low back pain, and headache. 14 developers were reported. 23 MAs were developed after 2013. The largest number of MAs were developed in the United States. The target age group of 12 MAs was above the age of 3, and that of 11 MAs was above the age of 12. 14 MAs provided multimedia functions such as videos. 13 MAs provided information of expertise. From clinical studies, only 3 out of 6 MAs were accessible through the app market. 4 MAs were developed by the researchers of the study. In terms of MARS, the score of MAs from the app market was higher than that of MAs from clinical studies in both objective and subjective evaluation areas. Conclusions : This study summarizes the characteristics of MAs using self-acupressure. More MAs using self-acupressure should be developed and further clinical research for MA on each symptom and disease is warranted for the diversification of MA fields using self-acupressure.

Effects of Curcumae longae Rhizoma and Cinnamomi Ramulus Mixture on Anti-inflammatory Activities in Lipopolysaccharide-stimulated RAW 264.7 Cells (강황(薑黃) 계지(桂枝) 복합물이 RAW 264.7 세포에서 항염증 활성에 미치는 영향)

  • Ji, Choi;Hae-Jin, Park;Il-ha, Jeong;Min Ju, Kim;Mi-Rae, Shin;Seong-Soo, Roh;Soon-Ae, Park;Mi-Lim, Kim
    • The Korea Journal of Herbology
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    • v.38 no.2
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    • pp.17-26
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    • 2023
  • Objectives : A persistent inflammatory response can cause diseases such as fibrosis, cancer, and allergies. This study aimed to investigate the anti-inflammatory activity of Curcumae longae Rhizoma and Cinnamomi Ramulus Mixture (CCM) in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Methods : The total polyphenol and flavonoid contents of CCM were confirmed through an in vitro experiment. Also, radical scavenging activities of 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and Hydroxyl were confirmed. Moreover, ferric reducing antioxidant power (FRAP) activity were confirmed. After, CCM (50, 100, and 200 ㎍/mL) were applied to 0.1 ㎍/mL LPS-stimulated RAW264.7 cells. The levels of nitric oxide (NO) and pro-inflammatory cytokines in the supernatant fraction were determined. Also, the expressions of mitogen-activated protein kinase (MAPK) and nuclear factor-κB (NF-κB) pathways were detected using Western blot. Results : As a result of in vitro experiments, there was an excellent antioxidant activity in CCM-treated cells. In addition, in RAW264.7 cells stimulated with LPS, the increased NO level was inhibited in a concentration-dependent manner by the treatment of CCM. In addition, inflammatory cytokines production were significantly inhibited in a concentration-dependent manner in CCM-treated group. CCM treatment significantly decreased the protein expressions of MAPKs. Moreover, the expressions of NF-κBp65 and cyclooxygenase-2 (COX-2) were significantly decreased when 200 mg/kg of CCM was applied, and phospho-inhibitor of nuclear factor kappa B-α (p-IκBα) and inducible nitric oxide synthase (iNOS) were significantly decreased at all concentrations treated with CCM. Conclusion : Our findings show that CCM exhibited excellent antioxidant activity and exhibited superior anti-inflammatory effect through the MAPKs and NF-κB pathways in LPS-stimulated RAW 264.7 macrophages.

Analysis of difference in body fluid composition and dietary intake between Korean adults with and without type 2 diabetes mellitus (한국성인의 제2형 당뇨병 유무에 따른 체액 조성 차이 및 영양소 섭취량 분석)

  • Yu-Gyeong Kim;Ha-Neul Choi ;Jung-Eun Yim
    • Journal of Nutrition and Health
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    • v.56 no.4
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    • pp.377-390
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    • 2023
  • Purpose: Diabetes mellitus (DM) causes body fluid imbalance because of hyperglycemia, but there is a lack of research on the relationship between DM and body fluid imbalance in the Korean population. This study compared the differences in body fluid composition and dietary intake between individuals with type 2 DM (T2DM) and a normal control (NC) group without the disease. Methods: In this study, 36 subjects with T2DM and 21 without diabetes were divided into the T2DM and NC groups. The subjects were divided into four subgroups to assess differences in body fluid volume according to sex: men T2DM group (n = 24), men NC group (n = 9), women T2DM group (n = 12), and women NC group (n = 12). The body fluid composition was measured using bioelectrical impedance analysis, including intracellular water (ICW), extracellular water (ECW), total body water (TBW), ECW/ICW, and ECW/TBW. Nutrient intake was evaluated using their dietary records. Results: The results showed that the ECW/ICW and the ECW/TBW were significantly higher in the T2DM group compared to the NC group. Both men and women in the T2DM group showed significantly higher ECW/ICW and ECW/TBW than the respective NC group. The T2DM group had a higher carbohydrate, dietary fiber, vitamin A, vitamin C, sodium, and potassium intake per 1,000 kcal and lower total daily energy, fat, and cholesterol intake per 1,000 kcal than the NC group. Conclusion: These results suggest a positive association between T2DM and body fluid imbalance. This study can be used widely as basic data for the evaluation and diagnosis of diabetic complications in the future.