• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2011년도 추계학술발표대회
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• pp.819-822
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• 2011

2006년 12월 1일 FRCP 개정안이 발표되면서 e-Discovery를 제정함으로 기업 시스템 내의 ESI에 대한 통합적인 관리가 필요하게 되었다. e-Discovery는 시스템 내의 ESI들을 모두 검토해야 함으로 비용과 시간을 줄이기 위한 e-Discovery 지원 도구가 필요하다. 하지만 국내의 e-Discovery 분야는 거의 시작단계이거나 이제 시작해야 하는 단계라고 볼 수 있으며, e-Discovery 지원 도구들은 외국산 s/w가 대부분이다. 본 논문에서는 e-Discovery 분야에서 가장 중요하다고 볼 수 있는 ESI 수집을 위해 이용되는 여러 e-Discovery 도구들의 기능을 분석하여 어떤 시스템에도 유연성있게 구축될 수 있는 개방적인 오픈소스 기반의 ESI 수집 지원 도구의 설계를 제안한다.

• Journal of Preventive Medicine and Public Health
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• 제49권2호
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• pp.129-133
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• 2016

Objectives: The systematic review (SR) is a research methodology that aims to synthesize related evidence. Updating previously conducted SRs is necessary when new evidence has been produced, but no consensus has yet emerged on the appropriate update methodology. The authors have developed a new SR update method called 'adaptive meta-analysis' (AMA) using the 'cited by', 'similar articles', and 'related articles' citation discovery tools in the PubMed and Scopus databases. This study evaluates the usefulness of these citation discovery tools for updating SRs. Methods: Lists were constructed by applying the citation discovery tools in the two databases to the articles analyzed by a published SR. The degree of overlap between the lists and distribution of excluded results were evaluated. Results: The articles ultimately selected for the SR update meta-analysis were found in the lists obtained from the 'cited by' and 'similar' tools in PubMed. Most of the selected articles appeared in both the 'cited by' lists in Scopus and PubMed. The Scopus 'related' tool did not identify the appropriate articles. Conclusions: The AMA, which involves using both citation discovery tools in PubMed, and optionally, the 'related' tool in Scopus, was found to be useful for updating an SR.

• 한국도서관정보학회지
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• 제45권3호
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• pp.415-440
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• 2014

이 연구에서는 빠르게 도입되고 있는 디스커버리에 대한 이해를 돕고, 통합탐색도구로서 우리 도서관목록의 유용성을 증대하는데 기여할 수 있는지 그 가능성과 한계를 가늠해 보고자 한다. 구체적으로, 이 연구는 관련 문헌에 대한 조사와 분석에 근거하여, (1) 디스커버리가 등장하게 된 배경과 개념 및 유형 등 디스커버리의 실체를 살펴보고, (2) 디스커버리 통합색인의 품질평가를 위한 기준과 지표를 개발하고, (3) 도출된 기준과 지표에 따라 디스커버리에서 제공하는 통합색인의 질적 수준을 평가한 뒤, (4) 디스커버리의 도입에 앞서 우리 학계와 도서관계가 고민해야 할 과제와 취해야 할 전략에 대해서 논의하고자 한다. 이를 위해, 이 연구에서는 EDS를 사용하는 P대학도서관을 사례로 하여 371건의 표본 레코드를 추출한 뒤, 이를 대상으로 디스커버리 통합색인의 품질평가를 수행하였다.

• Journal of Information Science Theory and Practice
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• 제10권4호
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• pp.3-22
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• 2022

This paper provides an overview of the emergence of resource discovery systems and services, along with their advantages, best practices, and current landscapes. It outlines some of the key services and functionalities of a comprehensive discovery model suitable for academic libraries in developing countries. The proposed model (VuFind as a discovery tool) performs like other existing web-scale resource discovery systems, both commercial and open-source, and is capable of providing information resources from different sources in a single-window search interface. The objective of the paper is to provide seamless access to globally distributed subscribed as well as open access resources through its discovery interface, based on a unified index. This model uses Koha, DSpace, and Greenstone as back-ends and VuFind as a discovery layer in the front-end and has also integrated many enhanced search features like Bento-box search, Geodetic search, and full-text search (using Apache Tika). The goal of this paper is to provide the academic community with a one-stop shop for better utilising and integrating heterogeneous bibliographic data sources with VuFind (https://vufind.org/vufind).

• Journal of Information Science Theory and Practice
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• 제4권3호
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• pp.71-83
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• 2016

Purpose. The purpose of this paper is to analyze and evaluate discovery layer search tools for retrieval of legal information in Indian law libraries. This paper covers current practices in legal information retrieval with special reference to Indian academic law libraries, and analyses its importance in the domain of law.Design/Methodology/Approach. A web survey and observational study method are used to collect the data. Data related to the discovery tools were collected using email and further discussion held with the discovery layer/ tool /product developers and their representatives.Findings. Results show that most of the Indian law libraries are subscribing to bundles of legal information resources such as Hein Online, JSTOR, LexisNexis Academic, Manupatra, Westlaw India, SCC web, AIR Online (CDROM), and so on. International legal and academic resources are compatible with discovery tools because they support various standards related to online publishing and dissemination such as OAI/PMH, Open URL, MARC21, and Z39.50, but Indian legal resources such as Manupatra, Air, and SCC are not compatible with the discovery layers. The central index is one of the important components in a discovery search interface, and discovery layer services/tools could be useful for Indian law libraries also if they can include multiple legal and academic resources in their central index. But present practices and observations reveal that discovery layers are not providing facility to cover legal information resources. Therefore, in the present form, discovery tools are not very useful; they are an incomplete and half solution for Indian libraries because all available Indian legal resources available in the law libraries are not covered.Originality/Value. Very limited research or published literature is available in the area of discovery layers and their compatibility with legal information resources.

• Biomolecules & Therapeutics
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• 제22권4호
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• pp.267-274
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• 2014

Drug development and preclinical trials are challenging processes and more than 80% to 90% of drug candidates fail to gain approval from the United States Food and Drug Administration. Predictive and efficient tools are required to discover high quality targets and increase the probability of success in the process of new drug development. One such solution to the challenges faced in the development of new drugs and combination therapies is the use of low-cost and experimentally manageable in vivo animal models. Since the 1980's, scientists have been able to genetically modify the mouse genome by removing or replacing a specific gene, which has improved the identification and validation of target genes of interest. Now genetically engineered mouse models (GEMMs) are widely used and have proved to be a powerful tool in drug discovery processes. This review particularly covers recent fascinating technologies for drug discovery and preclinical trials, targeted transgenesis and RNAi mouse, including application and combination of inducible system. Improvements in technologies and the development of new GEMMs are expected to guide future applications of these models to drug discovery and preclinical trials.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.87-90
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• 2012

Cholangiocarcinoma (CCA) is the most common cancer in northeastern Thailand. At present, effective diagnosis of CCA either in humans or animals is not available. Monitoring the development and progression of CCA in animal models is essential for research and development of new promising chemotherapeutics. Ultrasonography has been widely used for screening of bile duct obstruction in CCA patients. In this study, we preliminarily investigated the applicability of ultrasonography to monitor the development and progression of CCA in Syrian golden hamsters (n=8) induced by Opisthorchis viverrini (OV)/dimethylnitrosamine (DMN) administration. Ultrasonography and histopathological examination of hamsters was performed at week 0, 20, 24 and 28 of OV infection or at the start of water/Tween-80 administration to controls. The ultrasonographic images of liver parenchyma and gallbladders of OV/DMN-induced CCA hamsters showed sediments in gallbladder, thickening of gallbladder wall, and hypoechogenicity of liver parenchyma cells. The ultrasonographic images of liver tissues were found to correlate well with histopathological examination. Although ultrasonography does not directly detect the occurrence of CCA, it reflects the thickening of bile ducts and abnormality of liver tissues. It may be applied as a reliable tool for monitoring the development and progression of CCA in animal models in research and development of new promising chemotherapeutics for CCA.

• Applied Microscopy
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• 제51권
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• pp.13.1-13.7
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• 2021

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has arisen as a global pandemic affecting the respiratory system showing acute respiratory distress syndrome (ARDS). However, there is no targeted therapeutic agent yet and due to the growing cases of infections and the rising death tolls, discovery of the possible drug is the need of the hour. In general, the study for discovering therapeutic agent for SARS-CoV-2 is largely focused on large-scale screening with fragment-based drug discovery (FBDD). With the recent advancement in cryo-electron microscopy (Cryo-EM), it has become one of the widely used tools in structural biology. It is effective in investigating the structure of numerous proteins in high-resolution and also had an intense influence on drug discovery, determining the binding reaction and regulation of known drugs as well as leading the design and development of new drug candidates. Here, we review the application of cryo-EM in a structure-based drug design (SBDD) and in silico screening of the recently acquired FBDD in SARS-CoV-2. Such insights will help deliver better understanding in the procurement of the effective remedial solution for this pandemic.

• 정보관리학회지
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• 제33권4호
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• pp.125-157
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• 2016

해외에 진출한 국내기업의 소송 사례가 증가하면서 기업들의 전자증거개시제도의 대응에 대한 요구가 증가하고 있다. 영미법에서 유래된 제도인 전자증거개시제도는 절차 진행과정에서 여러 곳에 산재해 있는 전자적 정보들을 중 제한된 시간 내에 소송과 관련된 전자적 정보들을 찾아 증거자료로 검토하여 제출하는 제도이다. 이는 하루에도 수많은 전자기록이 생산되는 국내기업들의 기록관리가 잘 이루어지지 않고 있는 현실에서 제한된 시간 이내에 증거자료를 추리고 검토하여 제출하는 것은 쉽지 않은 일이다. 검토대상을 줄이고 검토과정을 효율적으로 진행하는 것은 소송에서 승소를 위한 가장 중요한 과제 중 하나이다. Predictive Coding은 전자증거개시 검토 과정에서 사용되는 도구로써 기계학습을 이용하여 기업들이 보유하고 있는 전자적 정보들의 검토를 도와주는 도구이다. Predictive Coding이 기존의 검색도구보다 효율성이 높고 잠재적으로 소송과 관련된 전자적 정보를 추려내는데 강점이 있다고 판단된다. 기업의 효율적인 검색도구의 선택과 지속적인 기록관리를 통해 검토비용의 시간적, 비용적 절감을 꾀할 수 있을 것으로 예상된다. 따라서 기업은 전자증거개시 제도에 대응하기 위해서 시간과 비용적 측면을 고려한 전문적인 Predictive Coding 솔루션의 도입과 기업 기록관리를 통해 가장 효과적인 방법을 모색해야 할 것이다.

• Architectural research
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• 제12권2호
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• pp.1-7
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• 2010

Science (natural science) is the systematic attempt to understand and interpret the nature phenomenon. For this reason, architects have used science to adapt nature to their design. With the rise of modern science, architecture became more closely related with science. Science available to develop new technology for architecture and it influenced architect's idea and concept. Symbolically, Architects use method or process of science to generate building form. The Rules of compositing particles in the chemistry or DNA (deoxyribonucleic acid) in the biology are used to generate a form of building. Literally, Architects use technology as a tool of science to improve physical performance of architecture. Like mathematical understanding of structure load enabled people to construct enclosure without columns or any of support system inside of architecture. Still natural phenomenon is not fully understood as science and science is still discovering a new phenomenon or changing its theory to adapt new discovery. New discovery or limitation of science influenced architecture throughout the history. This paper is to discuss how architectural theories are rest upon idea set forth by science. In addition, how technology as a tool of science has been utilized in architecture.