• Asian Journal of Atmospheric Environment
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• v.5 no.4
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• pp.205-215
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• 2011

Ozone ($O_3$) is a main component of photochemical oxidants and a phytotoxic air pollutant. Although the current levels of tropospheric $O_3$ in East Asia could adversely affect productivity of forest tree species, risk assessments of $O_3$ impact were limited. In this paper, we summarize the methodology of risk assessment of $O_3$ on forest tree species based on our two previous studies, risk assessments of $O_3$ impact on the growth of Fagus crenata by Watanabe et al. (2012) and on the annual carbon absorption of three representative conifers, Cryptomeria japonica, Pinus densiflora and Larix kaempferi by Watanabe et al. (2010). $O_3$ sensitivity of each tree species obtained from an experimental study, $O_3$ exposure and atmospheric N deposition based on field monitoring and vegetation survey were integrated by geographic information system method. Based on the results, we conclude that the area with high risk of $O_3$ impact does not necessarily correspond to the area with high $O_3$ exposure. The varieties of tree habitat, tree sensitivity to $O_3$ and annual carbon absorption among the tree species, and N deposition-induced change in the $O_3$ sensitivity of F. crenata are raised as the factors of discordance between areas with high risk and those with high $O_3$ exposure. In the last part of this paper, we discuss the present uncertainty and perspectives of risk assessment for the future studies on the impact of $O_3$ on forest tree species in East Asia.

• Journal of the Korean Society of Costume
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• v.58 no.3
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• pp.131-148
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• 2008

Each stylistic period through history has its own unique look. The characteristic look of each period is completed and visualized with its prevailing ideologies, aesthetic consciousness and morality by means of 'form'. A period expresses its characteristics in accordance with form according to the widespread preferences of the time. Among the various cultural factors that form the look of the time, those that the period holds as ideal aesthetic values create the concept of 'ideal beauty' for that period. This study begins by establishing the conceptual definition of 'ideal beauty' and develops the premise that dress reflected ideal beauty. To attain the goal of the study, the selected objects are dresses represented in paintings, the actual garments from the Renaissance to Baroque periods and written references about art, art history, and history of costume. The results, based upon a theoretical study of the zeitgeist and aesthetic values of the 16th and 17th centuries, are as follows: first, ideal beauty influences the substance and form that constitute dress style. It is a byproduct of the spirit of time, the zeitgeist. The concept of ideal beauty is born within the lifestyle pursued by the ruling class and focuses on the body as an epitome of beauty, moral values, custom, lifestyle and taste as it becomes visualized via form. Second, the aspect of dress representing the ideal beauty of particular time varied according to the times. In both periods, power and dignity were used to achieve the ideal aesthetic values. In the Renaissance, power was expressed by the horizontal extension of dress (i.e. wide farthingales and sleeves) and in the Baroque period, by vertical extension (i.e. long and tall wigs, fontanges and trains). It can be said that fashion in both periods achieved an ideal, such as power and dignity, via the same means, by extending dress sizes, but the ways in which those ideals were portrayed in each period's dress yielded very contrary styles. It is understood through this study that ideal beauty influenced the dress style of the Renaissance and Baroque periods and played a decisive role in determining its forms and symbolic meanings.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4493-4497
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• 2014

Background: Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) can predict the clinical response to tyrosine kinase inhibitor (TKI) therapy. However, EGFR mutations may be different in primary tumors (PT) and metastatic lymph nodes (MLN). The aim of this study was to compare EGFR mutations between PT and the corresponding MLN in NSCLC patients, and provide some guidelines for clinical treatment using TKI therapy. Materials and Methods: A systematic review and meta-analysis was performed with several research databases. Relative risk (RR) with the 95% confidence interval (CI) were used to investigate the EGFR mutation status between PT and the corresponding MLN. A random-effects model was used. Results: 9 publications involving 707 patients were included in the analysis. It was found that activation of EGFR mutations identified in PT and the corresponding MLN was 26.4% (187/707) and 19.9% (141/707), respectively. The overall discordance rate in our meta-analysis was 12.2% (86/707). The relative risk (RR) for EGFR mutation in PT relative to MLN was 1.33 (95%CI: 1.10-1.60; random-effects model). There was no significant heterogeneity between the studies ($I^2$=5%, p=0.003). Conclusions: There exists a considerable degree of EGFR mutation discrepancy in NSCLC between PT and corresponding MLN, suggesting that tumor heterogeneity might arise at the molecular level during the process of metastasis.

• The Research Journal of the Costume Culture
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• v.28 no.4
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• pp.420-428
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• 2020

This study analyzed the expression of hanbok in online fashion styling games, and examined the main themes of and user reactions to hanbok fashion styling games through semantic network analysis and sentiment analysis. KrKwic, Textom, and NodeXL were used for data collection and analysis. The findings of the study are as follows: First, depending on the designer's expressive method, hanbok fashion styling games provide typical traditional hanbok, modern hanbok, and dress-like fusion hanbok, demonstrating contents with various themes for different sexes, classes, and situations. Second, as a result of analyzing the themes of hanbok-related styling game contents, it turned out that the main themes are tradition, color, historical drama, fusion hanbok, holiday, and love. Most of them produce modernized hanbok that reflect the situation and utility rather than strictly traditional ones. Third, as a result of analyzing user reviews of hanbok styling game contents, positive factors mostly turned out to be the satisfaction of the hanbok contents, with the users also showing positive intent to wear hanbok. Through this, it was found out that hanboks portrayed in game contents could potentially cause the user's positive intent to wear hanbok. Negative factors turned out to be the discordance between the intrinsic image of hanbok and the game character's image.

• Clinical and Experimental Pediatrics
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• v.60 no.9
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• pp.282-289
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• 2017

Purpose: Recent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of 27 patients with global developmental delay. Methods: We included 27 children who fulfilled the following criteria: Korean children under 6 years with global developmental delay; children who had at least one or more physical or neurological problem other than global developmental delay; and patients in whom both array CGH and G-banded karyotyping tests were performed. Results: Fifteen male and 12 female patients with a mean age of $29.3{\pm}17.6months$ were included. The most common physical and neurological abnormalities were facial dysmorphism (n=16), epilepsy (n=7), and hypotonia (n=7). Pathogenic copy number variation results were observed in 4 patients (14.8%): 18.73 Mb dup(2)(p24.2p25.3) and 1.62 Mb del(20p13) (patient 1); 22.31 Mb dup(2) (p22.3p25.1) and 4.01 Mb dup(2)(p21p22.1) (patient 2); 12.08 Mb del(4)(q22.1q24) (patient 3); and 1.19 Mb del(1)(q21.1) (patient 4). One patient (3.7%) displayed a variant of uncertain significance. Four patients (14.8%) displayed discordance between G-banded karyotyping and array CGH results. Among patients with normal array CGH results, 4 (16%) revealed brain anomalies such as schizencephaly and hydranencephaly. One patient was diagnosed with Rett syndrome and one with $M{\ddot{o}}bius$ syndrome. Conclusion: As chromosomal microarray can elucidate the cause of previously unexplained developmental delay, it should be considered as a first-tier cytogenetic diagnostic test for children with unexplained developmental delay.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.7
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• pp.4786-4797
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• 2015

The purpose of this study was to understand the subjectivity on health and lifestyle of middle aged women and to explore the relationship between health and lifestyle. Q methodology was applied of the study. 29 statements for health and 27 statements for lifestyle were classified by 30 women of the age 40~60 years living in Seoul. The obtained data were analyzed by means of PC Quanl program. The result showed that the health and lifestyle of middle aged women were classified in 4 types and the characteristics and the relationship between health and life style have been identified. The types of health included 'health worrying type', 'daily living management type', 'discordance between one's words and action type', and 'early management type'. The types of lifestyle included 'occupation focused type', 'self norm value type', 'satisfying type', and 'religion focused type'. This study provided basic data to improve the health and life style of middle aged women, as well as to supply theoretical frame to prepare individualized nursing interventions.

• Economic and Environmental Geology
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• v.19 no.2
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• pp.147-151
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• 1986

K-Ar ages on biotites have been determined from the Proterozoic Buncheon and Hongjesa granitic rocks in comparison with the Rb-Sr whole-rock ages to investigate the ages of metamorphic events. The Rb-Sr whole-rock ages determinations on the Buncheon and Hongjesa granitoid rocks were previously reported as 2,100Ma and 1,700Ma, respectively. K-Ar ages on biotites separated from the studied rock have revealed three different age groups such as 1) 1,200~1,300Ma, 2) 600~700Ma and 3) 300~400Ma. The Rb-Sr whole-rock ages for the granitic rocks represent the time of emplacement, whereas the K-Ar ages on biotites generally indicate the time of metamorphism or alteration. The large discordance in the two age systems may not be explained as indicating the cooling period of the granitic batholiths. The K-Ar ages on biotites from the granitoid rocks might not be simply interpreted as the age of the last phase of metamorphism, since the granitic rocks had been undergone multistages of amphibolite facies-metamorphism in the Precambrian period. During the multistages of intermediate grade metamorphism, $^{40}Ar$-loss could be inevitably taken place as the metamorphic temperatures went up above the blocking temperature of biotite ($300{\pm}50^{\circ}C$). The results of the K-Ar dating on biotites from this study are probably minimum ages or hydrothermal alteration ages.

• Korean System Dynamics Review
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• v.13 no.3
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• pp.47-66
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• 2012

This paper aims at investigating and identifying the factor that has led the back and forth relationship between China and the United States since 1989. Previous studies on this subject addressed the issue by taking either of two approaches: one with the micro view that interprets the back and forth relationship in the context of the end of the Cold war, on other hand, with the macro view that interprets the fragile relationship in the context of the rise of China. However, neither of the approaches explains with sufficiency the question at hand. Hence for the inquiry, this article suggests a fresh view by exploring alternative method of using a cognitive map of each nation's leader, Jiangzemin and Bill Clinton. This article provides an empirical analysis through the Selected works of Jiangzemin and the speeches of Bill Clinton in 1998 for the first time in the field of Sino-US relationship studies in Korea. With the results of the cognitive map analysis, we can reach the following four points. Firstly, indicators of the forth relationship between China and the US are: i) the recognition by Bill Clinton on the importance of China's economic growth and; ii) the US's cooperation of science technology with China. Second, the conflict between China and the US results from the discordance of opinions on the matter of human rights and military power. Second, the conflict will inevitably arise on environmental issues around the globe including a global warming. Third, while China has yet to find a legitimate reason to agree upon these issues with the US, the US urges China of its cooperation. Lastly, Both China and the US attach great importance to the alliance with Japan. This implicates that relatively, issues involving Japan take more control in the China-US relationship, than those of Korea Peninsula.

• The Korean Journal of Cytopathology
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• v.15 no.1
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• pp.33-39
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• 2004

We compared the diagnostic accuracy of liquid-based cervicovaginal cytology using $MonoPrep2^{TM}$ system (Monogen, Herndon, Virginia, USA), a manual system based on membrane filtration method, with conventional Pap smear. Study population included 92 patients visiting the gynecologic department under the suspicion of uterine cervical disease. In thirty of them, surgical biopsy was performed. $MonoPrep2^{TM}$ system provided well-preserved monolayer specimen with good nuclear morphology. However, about 19% of specimens were inadequate to interpret due to low cellularity. The detection rate of abnormal cells more than ASCUS (atypical squamous cells of unknown significance) was 23.9% and higher than 19.4 % of conventional Pap smear. Diagnostic concordance rate with conventional Pap smear was 81%, and severe discordance rate influencing on the management of patient was 7.6 %. Among these seven cases, $MonoPrep2^{TM}$ system was more diagnostic only in four. In comparison with histology, the sensitivity of diagnosis of $MonoPrep2^{TM}$ system was 78.9% and slightly higher than 73.5% of conventional Pap smear. However, the specificity was 81.1% and lower than 90.9% of Pap smear. In conclusion, $MonoPrep2^{TM}$ system provided diagnostic accuracies similar to the conventional Pap smear. The inexpertness of slide preparation and the low cellularity were considered to endow a limitation in more accurate evaluation.

• Parasites, Hosts and Diseases
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• v.51 no.4
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• pp.485-488
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• 2013

The performance values of available techniques used in serodiagnosis of toxoplasmosis are satisfactory but they raise problems of equivocal and discordant results for very low IgG titers. Recently marketed, LDBio-Toxo II IgG Western blot (IB) showed an excellent correlation with the dye test. We estimated the proportion of equivocal and discordant results between the enzyme immunoassay Platelia Toxo IgG (EIA-IgG) and fluorescent antibody test (FAT) and assessed the usefulness of the IB as a confirmatory test. Out of 2,136 sera collected from pregnant women, 1,644 (77.0%) tested unequivocally positive and 407 (19.0%) were negative in both EIA-IgG and FAT. The remaining 85 (4%) sera showed equivocal or discordant results. Among them, 73 (85.9%) were positive and 12 (14.1%) were negative in IB. Forty-one (89.1%) equivocal sera in EIA-IgG and 46 (86.8%) equivocal sera in FAT were positive in IB. Reducing the cut-off values of both screening techniques improved significantly their sensitivity in detecting very low IgG titers at the expense of their specificity. In conclusion, equivocal results in routine-used techniques and their discordance in determination of the immune status in pregnancy women were not uncommon. IB test appeard to be highly useful in these situations as a confirmatory technique.