• International Journal of Advanced Culture Technology
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• 제6권3호
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• pp.173-177
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• 2018

Masks are generated by adding different fonts of learning data characters in pixel unit, and pixel values belonging to each of the masks are divided into 3 groups. Using the directional expansion operators, we expand the text area of the test data character into 4 diagonal directions in order to create the boundary areas to distinguish it from the background area. A mask with a minimum average discordance is selected as the final recognition result by calculating the degree of discordance between the expanded test data and the masks. Image comparison using directional expansion operations more accurately recognizes test data through 4 subdivided recognition processes. It is also possible to expand the ranges of 3 groups of pixel values of masks more evenly such that new fonts can easily be added to the given learning data.

• 턱관절균형의학회지
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• 제1권1호
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• pp.23-27
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• 2011

This study reviews and suggests the followings: 1) The balance and harmony between water and fire (ki and blood, yin and yang) is regarded as the basic condition of maintaining health in Oriental medicine. 2) Oriental medicine defines disease as the imbalance or disharmony of body. So the discordance between water and fire is in ill state, the coordination between water and fire is in healthy state. 3) Etiological factors and pathology are summarized by the conflict between vital ki and pathogenic factors, six exogenous factors, internal injury by seven emotions and the imbalance between yin and yang. 4) The regulation of meridian ki recovers the balance between water and fire, ki and blood using acupuncture, moxibustion, cupping therapy, herbal medicine and physical and breathing exercise and massage which is based on the principle of controlling ki and spirit.

• 한국동물학회:학술대회논문집
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• 한국동물학회 2001년도 한국생물과학협회 학술발표대회
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• pp.123.2-123
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• 2001

No Abstract, See Full Text

• 한국초등수학교육학회지
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• 제15권2호
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• pp.301-316
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• 2011

본 연구에서는 초등학교 수학 교과서에서의 용어 사용에서, 교육과정과 교과서 사이의 불일치, 용어의 이중적 사용, 용어 정의 방식의 비일관성에 관해 사례를 들어 논의하고 있다. 사례 분석의 결론으로 다음의 네 가지를 제안할 수 있다. 첫째, 교과서와 교육과정을 일치시켜야 한다. 둘째, 교과서에서 사용하는 용어의 의미를 명확히 규정해야 한다. 셋째, 같은 종류의 용어를 정의할 때는 일관성 있게 정의해야 한다. 넷째, 교과서 개발 시스템의 보완이 필요하다. 본 연구의 결과는 새로운 교과서의 개발 및 교육과정의 수정 보완, 그리고 더 나아가 새로운 교육과정의 개발에 도움을 줄 수 있을 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4317-4321
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• 2015

Background: Prognostic biomarkers in breast cancer are routinely investigated in the primary tumors to guide further management. However, it is proposed that the expression may change during the disease progression, and may result in a different immune profile in the metastatic nodes. This work aimed to investigate the expression of breast prognostic biomarkers in primary tumors and in its axillary nodal metastasis, to estimate the possible discordant expression. Materials and Methods: 60 paired primary and axillary nodal metastasis samples were collected from patients with primary breast cancer with positive nodal deposits, diagnosed at the Maadi Military Hospital, Cairo, Egypt, during the year 2013. ER, PR and HER2 expression was assessed by immunohistochemistry in all samples Results: 48.3% of the included cases showed concordant results for both ER and PR receptors between the primary tumor and its nodal metastasis while 51.7% showed discordant results and the discordance level was statistically significant. On the other hand, 70% of the cases showed concordant Her2 results between the primary tumors and the nodal deposits, 30% showed discordant results and the difference was significant. Conclusions: The study indicated that the discordance in ER and PR receptor expression between the primary breast tumor and their nodal metastasis may be significant. The possible switch in the biomarker status during the disease progression is worth noting and may change the patient therapeutic planning. So, whether the treatment selection should be based on biomarkers in the lymph node is a topic for further studies and future clinical trials.

• Asian Pacific Journal of Cancer Prevention
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• 제15권24호
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• pp.10607-10611
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• 2015

Background: HER2 expression in the primary tumor and its lymph node metastases vary in gastric cancer, reflecting intratumoral heterogeneity. This finding also suggests that proliferation of a different clone in metastatic nodes is possible. In the current study, we aimed to determine the cause of discordance in HER-2 expression in the primary tumor and lymph node metastases for patients with gastric cancer. Materials and Methods: Eighty-one patients with gastric cancer who had undergone radical gastrectomy and were found to have lymph node metastasis upon pathological examination were included. Histopathological samples were obtained from biopsies obtained during patient gastrectomies and lymph node dissection. HER2 status was evaluated by both immunohistochemistry (IHC) and silver in situ hybridization (SISH). Results: Sixty-four (79%) patients were SISH (-), while 17 (21%) were SISH (+) in the primary tumor. However, in metastatic lymph nodes, HER2 status was SISH positive in 5 (28.3%) of the 64 SISH (-) primary tumor specimens. One of the 17 SISH (+) primary tumors was SISH (-) in the metastatic lymph nodes. Thus, SISH results for HER2 in both primary tumors and lymph node metastases were comparable, showing a concordance of 92.5%. In total, six patients demonstrated discordance between the primary tumor and lymph node metastases. The prevalence of HER2 discordance was significantly higher for patients in the pN2 and N3 stages (p=0.007). Although discordant patients had worse survival rates than concordant patients, the differences were not significant (p>0.05).Conclusions: Our study indicates that the frequency of concordance in HER2 status, as determined by IHC or SISH, is high in primary tumors and their corresponding lymph node metastases for patients with gastric cancer. If there is a discrepancy in HER2 status, its evaluation by both IHC and SISH may be useful for detecting patients who would benefit from trastuzumab, and it would therefore help guide decision-making processes in administering treatment.

• Advances in pediatric surgery
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• 제18권2호
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• pp.75-82
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• 2012

In one-stage transanal endorectal pull-through operation (TERPT) for Hirschsprung disease, preoperative evaluation by contrast enema (CE) is important tool in aspect of planning of surgical procedure as well as diagnosis. This study was to evaluate the significance of CE for identifying the extent of aganglionic bowel. A retrospective analysis was performed in 40 patients who underwent TERPT between 2003 and 2011. The authors reviewed the CE studies and their correlation with pathologic extent of aganglionosis. Total 66 contrast enemas were performed in 40 patients. Twenty patients underwent single CE, but 20 patients required multiple CEs. In single CE group, 17 had clear radiographic transition zone, but 3 had less definite transition zone. In multiple CE group, 17 patients who had equivocal finding in first or second CE had definite radiographic transition zone, but 3 patients of this group had less definite radiographic transition zones. Overall, 34 patients (85%)had clear radiographic transition zone by single or repeated CE. One (2.9%) out of 34 patients with clear radiographic transition zone had discordance between radiographic and pathologic transition zone. In contrast 4 (66.7%) out of 6 patients with equivocal radiographic transition zone had discordance between radiographic and pathologic transition zone. Observation of clear radiographic transition zone is important in preparation of TERPT, and repeated CE is helpful to reduce the discordance between radiographic and pathologic transition zone. Awareness of the possibility of discordance is also important if radiographic transitional zone is not clear.

• Human Ecology Research
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• 제51권5호
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• pp.563-571
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• 2013

This study aimed to investigate the effects of somatotypes and body-related variables such as body exposure and body satisfaction on underwear evaluative criteria. Usable questionnaires were obtained from a total of 250 male and female students in their 20s. The data were mainly analyzed by t-test, ANOVA and analysis of variance using SPSS ver. 21.0. The results of this study are as follows: First, differences between underwear and outerwear evaluative criteria were found. For example, size, comfort and washing were important for the underwear but design, brand and fashionability were meaningful for outerwear. Price, color, material, and sewing were important for both outerwear and underwear. Second, the groups divided by somatotypes, a thin person group, a moderate person group and a fat person group, showed no difference in underwear evaluative criteria. Members of all the somatotype groups evaluated underwear similarly. Third, the groups divided by body image distortion showed different evaluative criteria for underwear. The negative discordance group emphasized the importance of the practicality factor, but the positive discordance group stressed the significance of the symbolism factor. Finally, the groups divided by body exposure and body satisfaction showed different evaluative criteria for underwear, too. The effects of socio-cultural variables on the underwear evaluative criteria proved to be significant.

• 한국물환경학회지
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• 제26권4호
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• pp.700-706
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• 2010

Along the 4 major rivers in korea, there are automatic water quality monitoring (AWQM) stations to immediately respond to any pollution incident. Real-time data (temperature, DO, pH, EC and TOC) collected at each station were statistically treated to exclude outliers and keep valid data using Dixon's test and Discordance test. These applied methods were compared in terms of the number of the outliers sorted out. There was no significant difference between these methods. On the other hand, more outliers were sorted out from EC and TOC data, comparing with other water quality items. EC data did not show partly any variation for a long time at H station. If measured signal does not exceed ${\pm}0.001mS/cm$ from the sectional mean, the signal should be treated as normal data. Therefore, another routine was added to the data screening system, some data which were removed as outlier were restored.

• Journal of Preventive Medicine and Public Health
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• 제52권2호
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• pp.131-139
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• 2019

Objectives: Self-reporting can be used to determine the incidence and prevalence of hypertension (HTN). The present study was conducted to determine the validity of self-reported HTN and to identify factors affecting discordance between self-reported and objectively measured HTN in participants in the Ravansar Non-Communicable Diseases (RaNCD) cohort. Methods: The RaNCD cohort included permanent residents of Ravansar, Iran aged 35-65 years. Self-reported data were collected before clinical examinations were conducted by well-trained staff members. The gold standard for HTN was anti-hypertensive medication use and blood pressure measurements. The sensitivity, specificity, positive and negative predictive values, and overall accuracy of self-reporting were calculated. Univariate and multivariate logistic regression were used to examine the discordance between self-reported HTN and the gold standard. Results: Of the 10 065 participants in the RaNCD, 4755 (47.4%) were male. The prevalence of HTN was 16.8% based on self-reporting and 15.7% based on medical history and HTN measurements. Of the participants with HTN, 297 (18.8%) had no knowledge of their disease, and 313 (19.9%) had not properly controlled their HTN despite receiving treatment. The sensitivity, specificity, and kappa for self-reported HTN were 75.5%, 96.4%, and 73.4%, respectively. False positives became more likely with age, body mass index (BMI), low socioeconomic status, and female sex, whereas false negatives became more likely with age, BMI, high socioeconomic status, smoking, and urban residency. Conclusions: The sensitivity and specificity of self-reported HTN were acceptable, suggesting that this method can be used for public health initiatives in the absence of countrywide HTN control and detection programs.