• Title/Summary/Keyword: Direct evolution

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Endovascular Stroke Therapy Focused on Stent Retriever Thrombectomy and Direct Clot Aspiration : Historical Review and Modern Application

  • Kang, Dong-Hun;Park, Jaechan
    • Journal of Korean Neurosurgical Society
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    • v.60 no.3
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    • pp.335-347
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    • 2017
  • Intravenous recombinant tissue plasminogen activator had been the only approved treatment for acute ischemic stroke since its approval in 1995. However, the restrictive time window, numerous contraindications, and its low recanalization rate were all limitations of this modality. Under those circumstances, endovascular stroke therapy went through a great evolution during the past two decades of intravenous thrombolysis. The results of the 2013 randomized trials for endovascular stroke therapy were neutral, although they were limited by insufficient imaging screening at enrollment, early-generation devices with less efficacy, and treatment delays. Huge progress was made in 2015, as there were five randomized clinical trials which all demonstrated the safety and efficacy of endovascular stroke treatment. Despite differences in detail patient enrollment criteria, all 5 trials employed key factors for good functional recovery; (1) screening with non-invasive imaging to identify the proximal occlusion and exclude a large infarct core, (2) using highly effective modern thrombectomy devices mainly with stent retriever, and (3) establishment of a fast workflow to achieve effective reperfusion. The results of those trials indicate that modern thrombectomy devices can allow for faster and more effective reperfusion, which can lead to improved clinical outcomes compared to intravenous thrombolysis alone. These advances in mechanical thrombectomy are promising in the global fight against ischemic stroke-related disability and mortality. Two current mainstreams among such mechanical thrombectomy techniques, "stent retriever thrombectomy" and "direct clot aspiration", are the topic of this review. Stent retriever thrombectomy using Solitaire and Trevo retriever will be firstly discussed. And, the commonalities and the differences between two major clot aspiration thrombectomy techniques; a direct aspiration first pass technique (ADAPT) and forced arterial suction thrombectomy (FAST), will be additionally explained. Finally, details regarding the combination of direct clot aspiration and stent retriever thrombectomy, the switching strategy and the Solumbra technique, will be described.

Hardness and Microstructure evolution of SUS630 Stainless steel Fabricated by Directed Energy Deposition (Direct energy deposition 공정으로 제조된 SUS630 스테인리스강 적층조형체의 경도 및 미세조직 연구)

  • Back, Seong Eun;Noh, Kyung-Ho;Park, Jin Yong;Cho, Yong Ju;Kim, Jeoung Han
    • Journal of Powder Materials
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    • v.25 no.3
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    • pp.220-225
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    • 2018
  • The microstructure and mechanical characteristics of SUS630 specimens fabricated using the direct energy deposition (DED) process are investigated. In DED, several process parameters such as laser scan speed, chamber gas flow, powder carrier gas flow, and powder feed rate are kept fixed; the laser power is changed as 150 W, 180 W, and 210 W. As the laser power increases, the surface becomes smooth, the thickness uniformity improves, and the size and number of pores decreases. With the increase in laser power, the hardness deviation decreases and the average hardness increases. The microstructure of the material is columnar; pores are formed preferentially along the columnar interface. The lath-martensite phase governs the overall microstructure. The volumetric fraction of the retained austenite phase is measured to increase with the increase of laser input power.

Hybridal Method for the Prediction of Wave Instabilities Inherent in High Energy-Density Combustors (1): Modeling of Nonlinear Cavity Acoustics and its Evolution

  • Lee, Gil-Yong;Yoon, Woong-Sup
    • International Journal of Aeronautical and Space Sciences
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    • v.7 no.2
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    • pp.26-32
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    • 2006
  • This paper targets a direct and quantitative prediction of characteristics of unstable waves in a combustion chamber, which employs the governing equations derived in terms of amplification factors of flow variables. A freshly formulated nonlinear acoustic equation is obtained and the analysis of unsteady waves in a rocket engine is attempted. In the present formalism, perturbation method decomposes the variables into time-averaged part that can be obtained easily and accurately and time-varying part which is assumed to be harmonic. Excluding the use of conventional spatially sinusoidal eigenfunctions, a direct numerical solution of wave equation replaces the initial spatial distribution of standing waves and forms the nonlinear space-averaged terms. Amplification factor is also calculated independently by the time rate of changes of fluctuating variables, and is no longer an explicit function for compulsory representation. Employing only the numerical computation, major assumptions inevitably inherent, and in erroneous manner, in up to date analytical methods could be avoided. With two definitions of amplification factor, 1-D stable wave and 3-D unstable wave are examined, and clearly demonstrated the potentiality of a suggested theoretical-numerical method of combustion instability.

Application of FE approach to deformation analysis of RC elements under direct tension

  • Jakubovskis, Ronaldas;Kupliauskas, Rimantas;Rimkus, Arvydas;Gribniak, Viktor
    • Structural Engineering and Mechanics
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    • v.68 no.3
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    • pp.345-358
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    • 2018
  • Heterogeneous structure and, particularly, low resistance to tension stresses leads to different mechanical properties of the concrete in different loading situations. To solve this problem, the tension zone of concrete elements is reinforced. Development of the cracks, however, becomes even more complicated in the presence of bar reinforcement. Direct tension test is the common layout for analyzing mechanical properties of reinforced concrete. This study investigates scatter of the test results related with arrangement of bar reinforcement. It employs results of six elements with square $60{\times}60mm$ cross-section reinforced with one or four 5 mm bars. Differently to the common research practice (limited to the average deformation response), this study presents recordings of numerous strain gauges, which allows to monitor/assess evolution of the deformations during the test. A simple procedure for variation assessment of elasticity modulus of the concrete is proposed. The variation analysis reveals different deformation behavior of the concrete in the prisms with different distribution of the reinforcement bars. Application of finite element approach to carefully collected experimental data has revealed the effects, which were neglected during the test results interpretation stage.

Evolutionary Feature of Spray Droplets Exiting from a Direct-Injection Type Thruster Nozzle-Orifice (직접분사방식 추력기 노즐오리피스로부터 발생하는 분무입자의 발달특성)

  • Kim, Jin-Seok;Jung, Hun;Kim, Jeong-Soo;Park, Jeong;Kim, Sung-Cho
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2009.05a
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    • pp.149-152
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    • 2009
  • Spray characteristic parameters such as droplet mean velocity, diameter, and volume flux are measured at various locations of spray in order to investigate the evolutionary feature of droplets exiting from a direct-injection type thruster nozzle-orifice. The experimental results indicate that the large droplets with high velocity at the center of upstream are broken-up into smaller droplets with low velocity due to their continuous momentum loss to surrounding air along with spray evolution toward downstream. Also it is found that the high volume flux expands its distribution in radial direction as a results of spray spreading and dispersion.

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A Study on Remote Control of Multi DNC Network (Multi DNC Network의 구축에 관한 연구)

  • 김기혁;박재운;박영식
    • Journal of the Korea Society of Computer and Information
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    • v.7 no.4
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    • pp.33-39
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    • 2002
  • The present so many systems are used by evolution of Program to expel DNC(Direct Numerical Control) Network Infra for many CNC Controller. However, these systems is an inefficiency side in case of mutual connection at a long distance between Server Computer and Machining center Also, the machining center have so many controversial points in data transmission-receiver from the NC data server. So, this thesis well constructed the remote control system from CNC(Computer Numerical Control) Controller to CAD/CAM Server Computer. This system have some kinds of merits. Firstly. the machining center's user can easily use the saved NC data transmission from the CAD/CAM Server Secondly, the remote control is possible without the mutual conversation between the CAD/CAM Server and the machining center.

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Direct Observation on Pyrolysis of Some Plastics

  • Takasu, Tomio;Itou, Hideyuki;Shibata, Etsuro;Kasai, Eiki;Nakamura, Takashi
    • Proceedings of the IEEK Conference
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    • 2001.10a
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    • pp.742-745
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    • 2001
  • Plastics are one of difficult materials for recycling due to their characteristics in use. Recycling ratio of waste plastics was around 40% in last year in Japan, which includes energy recovery. Feed stock recycling and mechanical recycling are not easy because of additives in commercial plastics. Then, pyrolysis treatments have been done to recovery energy. Although plastics are easy to fire, complete combustion of them is not easy if anti-firing agents are added especially. Therefore, researches on pyrolysis or combustion behaviors of plastics containing additives are important from a view point recycling of plastics. Direct observation of popular plastics like polystyrene (PS), polycarbonate (PC), polyphenyle ether (PPE) and polyvinyl chloride (PVC) to investigate their pyrolysis behaviors in the present study. In case of PS, melting and gas evolution started at 9$0^{\circ}C$ and 39$0^{\circ}C$ respectively. And combustion finished at 445$^{\circ}C$. On the other hand, more than $600^{\circ}C$ and sufficient oxygen are required for complete combustion of PC and PPE.

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Effect of N2/Ar flow rates on Si wafer surface roughness during high speed chemical dry thinning

  • Heo, W.;Lee, N.E.
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.128-128
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    • 2010
  • In this study, we investigated the evolution and reduction of the surface roughness during the high-speed chemical dry thinning process of Si wafers. The direct injection of NO gas into the reactor during the supply of F radicals from NF3 remote plasmas was very effective in increasing the Si thinning rate, due to the NO-induced enhancement of the surface reaction, but resulted in the significant roughening of the thinned Si surface. However, the direct addition of Ar and N2 gas, together with NO gas, decreased the root mean square (RMS) surface roughness of the thinned Si wafer significantly. The process regime for the increasing of the thinning rate and concomitant reduction of the surface roughness was extended at higher Ar gas flow rates. In this way, Si wafer thinning rate as high as $20\;{\mu}m/min$ and very smooth surface roughness was obtained and the mechanical damage of silicon wafer was effectively removed. We also measured die fracture strength of thinned Si wafer in order to understand the effect of chemical dry thinning on removal of mechanical damage generated during mechanical grinding. The die fracture strength of the thinned Si wafers was measured using 3-point bending test and compared. The results indicated that chemical dry thinning with reduced surface roughness and removal of mechanical damage increased the die fracture strength of the thinned Si wafer.

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Electro-oxidation Kinetics of Cerium(III) in Nitric Acid Using Divided Electrochemical Cell for Application in the Mediated Electrochemical Oxidation of Phenol

  • Matheswaran, Manickam;Balaji, Subramanian;Chung, Sang-Joon;Moon, Il-Shik
    • Bulletin of the Korean Chemical Society
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    • v.28 no.8
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    • pp.1329-1334
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    • 2007
  • The electrochemical oxidation of cerium(III) was carried out using divided and undivided electrochemical cells in nitric acid medium. It was found that divided cell with Nafion 324 as the separator gave good conversion yield with high current efficiency compared to the undivided cell. The efficiency of the divided electrochemical cell was further optimized in terms of cell voltage, temperature, flow rate of solution recirculation, concentrations of Ce(III) and nitric acid. The better conditions for 1 M Ce(III) in 3 M nitric acid were found to be 2.5 V, 363 K and 100 mL/min recirculation flow rate based on the current efficiency under the experimental conditions investigated. The Ce(IV) oxidant produced was used as a mediator for the mineralization of phenol. The mineralization efficiency of the cerium mediated electrochemical oxidation was found rapid and higher compared to the direct electrochemical oxidation based on CO2 evolution under the same conditions.

THE LUMINOSITY-LINEWIDTH RELATION AS A PROBE OF THE EVOLUTION OF FIELD GALAXIES

  • GUHATHAKURTA PURAGRA;ING KRISTINE;RIX HANS-WALTER;COLLESS MATTHEW;WILLIAMS TED
    • Journal of The Korean Astronomical Society
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    • v.29 no.spc1
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    • pp.63-64
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    • 1996
  • The nature of distant faint blue field galaxies remains a mystery, despite the fact that much attention has been devoted to this subject in the last decade. Galaxy counts, particularly those in the optical and near ultraviolet bandpasses, have been demonstrated to be well in excess of those expected in the 'no-evolution' scenario. This has usually been taken to imply that galaxies were brighter in the past, presumably due to a higher rate of star formation. More recently, redshift surveys of galaxies as faint as B$\~$24 have shown that the mean redshift of faint blue galaxies is lower than that predicted by standard evolutionary models (de-signed to fit the galaxy counts). The galaxy number count data and redshift data suggest that evolutionary effects are most prominent at the faint end of the galaxy luminosity function. While these data constrain the form of evolution of the overall luminosity function, they do not constrain evolution in individual galaxies. We are carrying out a series of observations as part of a long-term program aimed at a better understanding of the nature and amount of luminosity evolution in individual galaxies. Our study uses the luminosity-linewidth relation (Tully-Fisher relation) for disk galaxies as a tool to study luminosity evolution. Several studies of a related nature are being carried out by other groups. A specific experiment to test a 'no-evolution' hypothesis is presented here. We have used the AUTOFIB multifibre spectro-graph on the 4-metre Anglo-Australian Telescope (AAT) and the Rutgers Fabry-Perot imager on the Cerro Tolalo lnteramerican Observatory (CTIO) 4-metre tele-scope to measure the internal kinematics of a representative sample of faint blue field galaxies in the red-shift range z = 0.15-0.4. The emission line profiles of [OII] and [OIII] in a typical sample galaxy are significantly broader than the instrumental resolution (100-120 km $s^{-l}$), and it is possible to make a reliable de-termination of the linewidth. Detailed and realistic simulations based on the properties of nearby, low-luminosity spirals are used to convert the measured linewidth into an estimate of the characteristic rotation speed, making statistical corrections for the effects of inclination, non-uniform distribution of ionized gas, rotation curve shape, finite fibre aperture, etc.. The (corrected) mean characteristic rotation speed for our distant galaxy sample is compared to the mean rotation speed of local galaxies of comparable blue luminosity and colour. The typical galaxy in our distant sample has a B-band luminosity of about 0.25 L$\ast$ and a colour that corresponds to the Sb-Sd/Im range of Hub-ble types. Details of the AUTOFIB fibre spectroscopic study are described by Rix et al. (1996). Follow-up deep near infrared imaging with the 10-metre Keck tele-scope+ NIRC combination and high angular resolution imaging with the Hubble Space Telescope's WFPC2 are being used to determine the structural and orientation parameters of galaxies on an individual basis. This information is being combined with the spatially resolved CTIO Fabry-Perot data to study the internal kinematics of distant galaxies (Ing et al. 1996). The two main questions addressed by these (preliminary studies) are: 1. Do galaxies of a given luminosity and colour have the same characteristic rotation speed in the distant and local Universe? The distant galaxies in our AUTOFIB sample have a mean characteristic rotation speed of $\~$70 km $s^{-l}$ after correction for measurement bias (Fig. 1); this is inconsistent with the characteristic rotation speed of local galaxies of comparable photometric proper-ties (105 km $s^{-l}$) at the > $99\%$ significance level (Fig. 2). A straightforward explanation for this discrepancy is that faint blue galaxies were about 1-1.5 mag brighter (in the B band) at z $\~$ 0.25 than their present-day counterparts. 2. What is the nature of the internal kinematics of faint field galaxies? The linewidths of these faint galaxies appear to be dominated by the global disk rotation. The larger galaxies in our sample are about 2"-.5" in diameter so one can get direct insight into the nature of their internal velocity field from the $\~$ I" seeing CTIO Fabry-Perot data. A montage of Fabry-Perot data is shown in Fig. 3. The linewidths are too large (by. $5\sigma$) to be caused by turbulence in giant HII regions.

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