• Asian-Australasian Journal of Animal Sciences
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• v.28 no.6
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• pp.763-770
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• 2015

Improved meat quality and greater muscle yield are highly sought after in high-quality chicken breeding programs. Past studies indicated that polymorphisms of the Perilipin gene (PLIN1) are highly associated with adiposity in mammals and are potential molecular markers for improving meat quality and carcass traits in chickens. In the present study, we screened single nucleotide polymorphisms (SNPs) in all exons of the PLIN1 gene with a direct sequencing method in six populations with different genetic backgrounds (total 240 individuals). We evaluated the association between the polymorphisms and carcass and meat quality traits. We identified three SNPs, located on the 5' flanking region and exon 1 of PLIN1 on chromosome 10 (rs315831750, rs313726543, and rs80724063, respectively). Eight main haplotypes were constructed based on these SNPs. We calculated the allelic and genotypic frequencies, and genetic diversity parameters of the three SNPs. The polymorphism information content (PIC) ranged from 0.2768 to 0.3750, which reflected an intermediate genetic diversity for all chickens. The CC, CT, and TT genotypes influenced the percentage of breast muscle (PBM), percentage of leg muscle (PLM) and percentage of abdominal fat at rs315831750 (p<0.05). Diplotypes (haplotype pairs) affected the percentage of eviscerated weight (PEW) and PBM (p<0.05). Compared with chickens carrying other diplotypes, H3H7 had the greatest PEW and H2H2 had the greatest PBM, and those with diplotype H7H7 had the smallest PEW and PBM. We conclude that PLIN1 gene polymorphisms may affect broiler carcass and breast muscle yields, and diplotypes H3H7 and H2H2 could be positive molecular markers to enhance PEW and PBM in chickens.

• IMMUNE NETWORK
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• v.6 no.1
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• pp.27-32
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• 2006

Background: Chronic inflammation in the brain has known to be associated with the development of a various neurological diseases including dementia. In general, the characteristic of neuro-inflammation is the activated microglia over the brain where the pathogenesis occurs. Pro-inflammatory repertoires, interleukin-1${\beta}$ (IL-1${\beta}$) and nitric oxide (NO), are the main causes of neuro-degenerative disease, particularly in Alzheimer's disease (AD) which is caused by neuronal destruction. Those pro-inflammatory repertoires may lead the brain to chronic inflammatory status, and thus we hypothesized that chronic inflammation would be inhibited when pro-inflammatory repertoires are to be well controlled by inactivating the signal transduction associated with inflammation. Methods: In the present study, we examined whether biphenyl dimethyl dicarboxylate (DDB), an active compound from Schizandra chinensis Baillon, inhibits the NO production by a direct method using Griess reagent and by RT-PCR in the gene expression of inducible nitric oxide synthase (iNOS) and IL-1${\beta}$. Western blots were also used for the analysis of NF-${\kappa}B$ and I${\kappa}B$. Results: In the study, we found that DDB effectively inhibited IL-1${\beta}$ as well as NO production in BV-2 microglial cell, and the translocation of NF-${\kappa}B$ was comparably inhibited in the presence of DDB comparing those to the positive control, lipopolysaccharide. Conclusion: The data suggested that the DDB from Schizandra chinensis Baillon may play an effective role in inhibiting the pro-inflammatory repertoires which may cause neurodegeneration and the results imply that the compound suppresses a cue signal of the microglial activation which can induce the brain pathogenesis such as Alzheimer's disease.

• Journal of Korea Water Resources Association
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• v.44 no.12
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• pp.929-940
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• 2011

In this study, the future expected discharges are analyzed for Daecheong and Yongdam Dam Watershed in Geum River watershed using A1B scenario based RCM with 27 km spatial resolutions from Korea Meteorological Agency and SWAT model. The direct use of GCM and RCM data for water resources impact assessment is practically hard because the spatial and temporal scales are different. In this study, the problems of spatial and temporal scales were settled by the spatial and temporal downscaling from watershed scale to weather station scale and from monthly to daily of RCM grid data. To generate the detailed hydrologic scenarios of the watershed scale, the multi-site non-stationary downscaling method was used to examine the fluctuations of rainfall events according to the future climate change with considerations of non-stationary. The similarity between simulation and observation results of inflows and discharges at the Yongdam Dam and Daecheong Dam was respectively 90.1% and 84.3% which shows a good agreement with observed data using SWAT model from 2001 to 2006. The analysis period of climate change was selected for 80 years from 2011 to 2090 and the discharges are increased 6% in periods of 2011~2030. The seasonal patterns of discharges will be different from the present precipitation patterns because the simulated discharge of summer was decreased and the discharge of fall was increased.

• Journal of Korean Society of Forest Science
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• v.26 no.1
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• pp.13-18
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• 1975

This study was intended to clarify interrelations among seven characters of bamboo and their influences upon its culm-volume. The analysis of covariance was used to obtain phenotypic correlations, genotypic correlations and environmental correlations among some characters of Phyllostachys bambusoides Sieb. et Zucc., and thereby path-coefficients were calculated based on Dewey's method. The characters considered here included the breast height diameter, culm-height, clear-length, subterranean stem, number of bamboo joints, butt-end diameter and culm-volume of bamboo. Average values, standard errors, variances and standard deviations for the characters mentioned above are shown in Table 1, and phenotypic correlations, genotypic correlations and environmental correlations among seven characters are shown in Table 2, according to the results, there are highly significant relationships among lines but not among some replications. According to Table 4, heritability values in the breast height and butt-end diameters are higher than those in other characters mentioned above. On the other hand, environmental correlations among general characters appear to have lower values than phenotypic and genotypic correlations do. It also appears that the butt-end diameter and breast height diameter are highly correlated with the culm-volume of bamboo. The path-coefficients of individual characters to the culm-volume of bamboo are computed from the correlations (Table 4) and presented in Figure 1 and Table 5, where it could shown the direct and indirect effects on the bamboo culm-volume of each character.

• Environmental and Resource Economics Review
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• v.14 no.1
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• pp.25-50
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• 2005

This study estimates the willingness-to-pay (WTP) for avoiding the destruction of a first-grade ecological area by means of contingent valuation method. Specifically, we employ the dichotomous choice technique along with the follow-up questionnaires. Our analysis implies the yearly WTP per household for avoiding the destruction of the ecological area of 100,000 pyongs is 8,898 won with the 95% confidence interval of 6,611~11,976 won. We estimate the asset value of that area to be 1,707 billion won with the 95% confidence interval of 1,269 to 2,298 billion won. We also decompose the total value of the area into the value of direct (22%) and indirect (38.8%) use, the option value (19.9%) and the conservation value (21.3%). Although using these data for SEEA (the system of integrated environmental economic accounting) is bound by certain restrictions, one could employ our empirical findings as advisory information for decision making in the process of prior environmental review or for assessing the environmental impact.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.3
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• pp.599-606
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• 2015

Damage of landslide due to earthquake covers a considerable part of total damage due to earthquake. Landslide due to earthquake affects direct damage of human lives and structures, and social system can be paralyzed by losing functions of roads, basic industries, and so on. Therefore, systematic and specialized research examining the factors affecting the slope stability by earthquakes should be needed. However, method of evaluation of slope stability problems due to earthquake contains somewhat uncertainty since many soil properties are predicted or assumed. In this study, influences of change of soil properties such as degree of saturation and cohesion value are analyzed in factor of safety and displacement using seismic landslide hazard maps based on GIS. As the degree of saturation increases or cohesion decreases, it is found that seismic landslide hazard area marked with factors of safety or displacements tends to increase. Therefore, to draw more exact landslide hazard map during earthquake, it is necessary to obtain accurate soil property information preferentially from site investigation data in the field.

• The Korean Journal of Nuclear Medicine
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• v.35 no.4
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• pp.251-257
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• 2001

Purpose: We investigated the possibility of early postoperative Tc-99m DTPA scintigraphy in predicting long-term renal transplant survival. Materials and Methods: 64 living donor (LD) grafts were divided into two groups according to the graft function on early post-operative renal scintigraphy. Survival analysis was performed using Kaplan-Meier method and Cox proportional hazard model. Chi-square test was performed to evaluate the difference in the frequency of acute rejection. Results: Cumulative renal transplant survival was decreased in 11 patients with abnormal renal scintigraphy, but it was not statistically significant. Decreased graft function on early post-operative renal scintigraphy was not a predictor of long-term graft survival. The frequency of acute rejection was higher in abnormal scintigraphy group, and the difference was statistically significant. Conclusion: Decreased graft function on early post-operative renal scintigraphy has no direct effect on long-term renal transplant survival in LD transplantation. But it may have an indirect elect through increasing the frequency of acute rejection.

• Journal of Technology Innovation
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• v.19 no.2
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• pp.99-128
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• 2011

University-to-industry technology transfer has become an increasingly important issue in recent years. Studies on technology transfer and commercialization evolved to diverse knowledge transfer channels. Among them, university spin-off is not only known as the most direct and tangible method but also suitable for effectively transferring tacit knowledge. Much of the studies on university spin-offs are mostly focused on macro-level but studies using the individual professors as their unit of analysis need better understanding as well. This paper investigates why the speed of university spin-off formations differ among individual professors drawing on the resource-based view. Utilizing data of 149 professors in 25 universities who formed spin-offs, Cox regression results suggest that professors' technological research capabilities, academic research capabilities and financial resources promote university spin-off formations.

• Journal of Biosystems Engineering
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• v.42 no.4
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• pp.350-357
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• 2017

Purpose: In-situ monitoring of water quality is fundamental to most environmental applications. The high cost and long delays of conventional laboratory methods used to determine water quality, including on-site sampling and chemical analysis, have limited their use in efficiently managing water sources while preventing environmental pollution. The objective of this study was to develop an on-site water monitoring system consisting mainly of an Arduino board and a sensor array of multiple ion selective electrodes (ISEs) to measure the concentration of $NO_3$ ions. Methods: The developed system includes a combination of three ISEs, double-junction reference electrode, solution container, sampling system consisting of three pumps and solenoid valves, signal processing circuit, and an Arduino board for data acquisition and system control. Prior to each sample measurement, a two-point normalization method was applied for a sensitivity adjustment followed by an offset adjustment to minimize the potential drift that could occur during continuous measurement and standardize the response of multiple electrodes. To investigate its utility in on-site nitrate monitoring, the prototype was tested in a facility where drinking water was collected from a water supply source. Results: Differences in the electric potentials of the $NO_3$ ISEs between 10 and $100mg{\cdot}L^{-1}$ $NO_3$ concentration levels were nearly constant with negative sensitivities of 58 to 62 mV during the period of sample measurement, which is representative of a stable electrode response. The $NO_3$ concentrations determined by the ISEs were almost comparable to those obtained with standard instruments within 15% relative errors. Conclusions: The use of the developed on-site nitrate monitoring system based on automatic sampling and two-point normalization was feasible for detecting abrupt changes in nitrate concentration at various water supply sites, showing a maximum difference of $4.2mg{\cdot}L^{-1}$ from an actual concentration of $14mg{\cdot}L^{-1}$.

• Korean Journal of Food Science and Technology
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• v.31 no.2
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• pp.441-447
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• 1999

Changes in flavor characteristics of roasted coffee in 6 package models during storage were investigated by GC/MS analysis and sensory evaluation to establish the criteria of the shelf-life of the roasted coffee in three flavor quality-'fresh', 'satisfying' and 'minimally acceptable' levels. In direct headspace method of GC/MS, 47 volatile compounds were analyzed and the light volatile compounds were reduced sharply at initial stage of storage and faster in the package with air. The correlation between % retention of 2,3-butanedione and overall aroma of roasted coffee showed good linear-relation, of which correlation coefficient (R) were from 0.999 to 0.904 depending on package models, indicating that 2,3-butanedione would be an index chemical for evaluating the freshness of roasted coffee. In sensory evaluation of 6 package models during storage, roasted whole beans (RB) and roasted and ground (RG) coffee in air-package were preserved in 'fresh quality' for $0.5{\sim}1$ week, 'satisfying quality' for $2{\sim}3$ weeks and 'minimally acceptable quality' for 12 weeks, while roasted whole beans in valve-package and roasted and ground coffees in vacuum-package, nitrogen-package and oxygen absorbent-package were preserved in 'fresh quality' for $2{\sim}4$ weeks, 'satisfying quality' for $12{\sim}24$ weeks and 'minimally acceptable quality' for 52 weeks. The oxygen absorbent-package was slightly less effective than other three methods.