• 제목/요약/키워드: Dilution Factors

검색결과 128건 처리시간 0.029초

혈관조영검사에서 매개변수 변화에 따른 Roadmap 영상의 화질평가 (Evaluation of Roadmap Image Quality by Parameter Change in Angiography)

  • 공창기;송종남;한재복
    • 한국방사선학회논문지
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    • 제14권1호
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    • pp.53-60
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    • 2020
  • 이 연구의 목적은 Roadmap 영상에서 화질에 영향을 미치는 인자들을 알아보기 위한 것으로, 조영제의 희석률, Collimation Field, Flow Rate를 변화하여 연구를 하였다. 화질의 정량적인 평가를 위해, 아크릴를 이용하여 3mm 혈관모형의 Water Phantom을 자체 제작하였고, 자체 제작한 혈관모형의 Water Phantom으로 Roadmap 영상을 획득하고, SNR(Signal to Noise Ratio)과 CNR(Contrast to Noise Ratio)을 분석하였다. CM : N/S 희석률 변화에 대한 연구에서 CM : N/S 희석률을 (100%~10% : 100%)로 변화를 주었으며, 혈관모형 Water Phantom을 이용하여 촬영한 Roadmap 영상의 SNR과 CNR의 측정 결과 CM에 N/S 희석률이 높아질수록 SNR의 측정값이 점차적으로 낮아짐을 나타났고, CNR의 측정값도 점차적으로 낮아짐을 나타났다. 결론적으로 CM : N/S의 희석률이 높아질수록 SNR과 CNR 낮아짐을 확인하였고, CM : N/S의 희석률(100%~70 : 30%)에서 유의한 이미지를 얻을 수 있음을 확인하였다. Collimation Field 변화에 대한 연구에서 혈관모형 Water Phantom을 이용하여 Colimation Field를 혈관모형 중심으로 좌, 우 2 cm 간격으로 좁히면서 0 cm, 2 cm, 4 cm, 6 cm, 8 cm 10 cm, 12 cm으로 각각 변화를 주었으며, Roadmap을 촬영한 영상의 SNR과 CNR의 측정 결과는 Collimation Field를 혈관모형 중심으로 좁힐수록 SNR과 CNR의 측정값이 증가하는 것을 확인할 수 있었다. Flow rate 변화에 대한 연구에서 Autoinjector의 Volume을 15로 일정하게 하고, Flow Rate를 1, 2, 3, 4, 5, 6, 7, 8, 9, 10 으로 각각 변화를 주었다. 혈관모형 Water Phantom을 이용하여 Roadmap 영상을 촬영한 이미지의 SNR과 CNR의 측정 결과 Flow Rate를 증가했을 때, SNR의 측정값이 점차적으로 감소하다가 Flow Rate 9~10에서 SNR의 측정값이 점차적 증가를 보였고, CNR의 측정값도 점차적으로 감소하다가 Flow Rate 9~10에서 CNR의 측정값이 점차적으로 증가를 보였다. 그러나 ROI Mean 값과 Background Mean 값으로 SNR과 CNR의 상관관계를 확인할 수 없었다. 상관관계를 확인하기 위해 Flow Rate 변화에 따른 Roadmap 연구는 향후 더 많은 연구로 확인해야 할 것으로 사료된다. 결론적으로 Roadmap 영상의 화질에 영향을 미치는 인자들을 알아보기 위해 조영제의 희석률, Collimation Field, Flow Rate 변화에 대한 연구에서 조영제에 N/S의 희석률이 증가할수록 SNR과 CNR이 낮아져 화질과 대조도가 낮아지는 것을 확인하였으며, Collimation Field를 좁힐수록 SNR과 CNR이 증가하여 화질과 대조도가 높아지는 것을 확인하였다. 그러나 Flow Rate 변화에 대한 연구에서는 상관관계를 확인할 수 없었다. 검사 및 시술을 할 때 신장의 영향을 최소화하기 위해 적절한 조영제 농도 선택과 대조도 향상 및 피폭 감소를 위한 적절한 Collimation Field를 사용하는 것이 유용할 것으로 판단된다.

환기 및 희석을 적용한 폭발위험장소 검토에 관한 연구 (A Study on the Examination of Explosion Hazardous Area Applying Ventilation and Dilution)

  • 김남석;임재근;우인성
    • 한국가스학회지
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    • 제22권4호
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    • pp.27-31
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    • 2018
  • 폭발위험장소의 구분은 인화성 물질을 취급하는 사업장에서 비용 및 안전 측면에서 매우 중요하다. 위험장소의 반경에 따라 전기기계 기구의 방폭기기 설치 여부가 결정되기 때문이다. 2017년 11월 6일부터 KS C IEC-60079-10-1:2015가 발행되어 새로운 기준으로 적용된다. 기존의 기준과 새로운 기준에 대한 차이를 이해하여 적용하는 것이 중요한 시점이다. 누출량 계산식에 누출계수 및 압축인자가 추가되었고 증발 풀 누출량 계산식, 누출공 크기 적용, 폭발위험장소의 모양이 추가 적용되었다. 안전계수 K값의 범위도 변경되었다. 또한 위험장소의 반경에는 기존기준은 가상체적에 환기횟수를 적용하였지만 개정기준은 누출 특성 값을 이용하여 산정된다. 본 연구에서는 환기 및 희석의 관점에서 기존 기준과의 차이점을 살펴보고 위험장소의 반경에 미치는 영향을 검토하였다. 기존 폭발위험장소를 선정한 기준과 개정기준을 기준으로 적용하여 비교 및 분석을 실시하였다. 연구결과 환기 및 희석이 잘 된다하더라도 실질적으로 위험반경에 영향이 없을 경우가 발생함을 알 수 있었다.

토양내 중금속 및 유류 오염농도 저감을 위한 생화학적 기작의 효율성 평가 (Assessment of Biochemical Efficiency for the Reduction of Heavy Metal and Oil Contaminants in Contaminated Soils)

  • 김만일;정교철;김을영
    • 지질공학
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    • 제22권3호
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    • pp.253-262
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    • 2012
  • 중금속 및 유류 오염토양 정화를 위해 효율적인 토양세척법과 공정 선정을 목적으로 최적의 오염정화 설계인자를 제시하기 위한 실험적 연구를 수행하였다. 실험 분석항목은 구리, 납, 아연을 포함하는 중금속 항목과 총석유계탄화수소(TPH)인 유류 항목에 대해 흡광광도법(absorptiometric analysis), 기체크로마토그래피(gas chromatography)법을 이용하여 단계별로 분석하였다. 실험방법은 최적 세척용매(washing solution) 결정시험, 최적 세척시간(washing time) 도출시험, 최적 진탕비(dilution ratio) 결정시험 등을 통해 얻어진 결과를 토대로 계면활성제(surfactant) 첨가량별 중금속 용출영향 분석시험, 미생물 및 과산화수소 주입시험 순으로 실시하였다. 실험결과에서 세척용매인 염산 0.1 mole, 체류시간 1시간, 진탕비 1 : 3 조건에서 오염물질의 저감효과가 우수하게 나타났으며, 이들 조건을 적용하였을 때 1%의 계면활성제를 세척 용매에 첨가하였을 경우 추가적인 오염물질의 농도저감 효과를 보이는 것으로 확인되었다. 또한 미생물과 과산화수소 주입에 따른 추가적인 TPH 농도 저감이 있는 것으로 파악되었다.

A Simulation Study on the Use of GPS Signals to Infer 3-D Atmospheric Wet Refractivity Structure

  • Chiang, Chen-Ching;Liou, Yuei-An
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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    • pp.1021-1023
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    • 2003
  • Atmospheric water vapor is a key variable in numerical weather prediction (NWP) models, but it is a crucial factor to limit the accuracy of high-precision GPS positioning technique. For both issues, knowledge about the amount of water vapor is extremely important. In this study, we perform a simulation study to utilize GPS signals through a developed tomographic scheme to retrieve 3D structure of atmospheric wet refractivity, which may be assimilated into NWP models for advancing forecasting or position calculation for improving GPS positioning accuracy. For the purpose of knowing the absolute accuracy of the developed tomographic method, a well-defined temporal and spatial varying state of atmospheric profile is utilized. Under such circumstance, several factors that may influence the retrievals can be easily examined and their impacts may be clearly quantified. They include the values of the positional dilution of precision (PDOP) factors of the GPS signals, ... etc. Based upon the use of a variety spectrum of adjustable factors, many interesting findings are obtained. For example, the more is the number of the observed GPS signals the better becomes the retrievals as expected. Also, the smaller is the PDOP value the better becomes the retrievals.

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USE OF NEAR INFRARED FOR THE QUANTITATIVE ANALYSES OF BAUXITE

  • Walker, Graham S.;Cirulis, Robyn;Fletcher, Benjimin;Chandrashekar, S.
    • 한국근적외분광분석학회:학술대회논문집
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    • 한국근적외분광분석학회 2001년도 NIR-2001
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    • pp.1171-1171
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    • 2001
  • Quantitative analysis is an important requirement in exploration, mining and processing of minerals. There is an increasing need for the use of quantitative mineralogical data to assist with bore hole logging, deposit delineation, grade control, feed to processing plants and monitoring of solid process residues. Quantitative analysis using X-Ray Powder Diffraction (XRD) requires fine grinding and the addition of a reference material, or the application of Rietveld analysis to XRD patterns to provide accurate analysis of the suite of minerals present. Whilst accurate quantitative data can be obtained in this manner, the method is time consuming and limited to the laboratory. Mid infrared when combined with multivariant analysis has also been used for quantitative analysis. However, factors such as the absorption coefficients and refractive index of the minerals requires special sample preparation and dilution in a dispersive medium, such as KBr to minimize distortion of spectral features. In contrast, the lower intensity of the overtones and combinations of the fundamental vibrations in the near infrared allow direct measurement of virtually any solid without special sample preparation or dilution. Thus Near Infrared Spectroscopy (NIR) has found application for quantitative on-line/in line analysis and control in a range of processing applications which include, moisture control in clay and textile processing, fermentation processes, wheat analysis, gasoline analysis and chemicals and polymers. It is developing rapidly in the mineral exploration industry and has been underpinned by the development of portable NIR spectrometers and spectral libraries of a wide range of minerals. For example, iron ores have been identified and characterized in terms of the individual mineral components using field spectrometers. Data acquisition time of NIR field instruments is of the order of seconds and sample preparation is minimal. Consequently these types of spectrometers have great potential for in-line or on-line application in the minerals industry. To demonstrate the applicability of NIR field spectroscopy for quantitative analysis of minerals, a specific example on the quantification of lateritic bauxites will be presented. It has been shown that the application of Partial Least Squares regression analysis (PLS) to the NIR spectra can be used to quantify chemistry and mineralogy in a range of lateritic bauxites. Important, issues such as sampling, precision, repeatability, and replication which influence the results will be discussed.

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중공사막 모듈을 이용한 정삼투 공정에서의 운영조건 변화에 따른 성능평가 (Performance evaluation of forward osmosis (FO) hollow fiber module with various operating conditions)

  • 김봉철
    • 상하수도학회지
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    • 제32권4호
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    • pp.357-361
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    • 2018
  • Forward osmosis (FO) process has been attracting attention for its potential applications such as industrial wastewater treatment, wastewater reclamation and seawater desalination. Particularly, in terms of fouling reversibility and operating energy consumption, the FO process is assumed to be preferable to the reverse osmosis (RO) process. Despite these advantages, there is a difficulty in the empirical step due to the lack of separation and recovery techniques of the draw solution. Therefore, rather than using FO alone, recent developments of the FO process have adapted a hybrid system without draw solution separation/recovery systems, such as the FO-RO osmotic dilution system. In this study, we investigated the performance of the hollow fiber FO module according to various operating conditions. The change of permeate flow rate according to the flow rates of the draw and feed solutions in the process operation is a factor that increases the permeate flow rate, one of the performance factors in the positive osmosis process. Our results reveal that flow rates of draw and feed solutions affect the membrane performance, such as the water flux and the reverse solute flux. Moreover, use of hydraulic pressure on the feed side was shown to yield slightly higher flux than the case without applied pressure. Thus, optimizing the operating conditions is important in the hollow fiber FO system.

토끼의 정상 및 핵이식배의 유리화 및 완만동결에 따른 융해 후 발달율 (Post-thaw Embryo Development following Vitrification or Slow Freezing of Rabbit Normal and Nuclear Transplant Embryos)

  • 강다원;최창용;하란조;강태영;심보웅;최상용;이효종;박충생
    • 한국수정란이식학회지
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    • 제13권1호
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    • pp.1-9
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    • 1998
  • In order to improve the cryopreservation by vitrification or slow freezing of nuclear transplant rabbit embryos, the effects of factors affecting embryo cryopreservation such as cryoprotectants, equilibration, cooling rate and post-thaw dilution on post-thaw survial and development were determined using intact embryos of morular stage. And the post-thaw development of nuclear transplanted embryos cryopreserved under the optimal conditions examined was compared between vitrification and slow freezing. The cryoprotectant solution used was ethyleneglycol-ficoll-sucrose (EFS) or ethyleneglycol-poly-vinylpyrrolidone-galactose- I (EPG- I ) for vitrification, and EPG- II for slow freezing. To examine the viability of frozen-thawed embryos, the nuclear transplanted embryos were co-cultured in TCM-199 plus 10% FBS with bovine oviduct epithelial cells(BOEC) for 24 hrs and the intact morulae were co-cultured with BOEC for 5 days and 3 days to hatching blastocyst stage in 39 ˚C 5% $CO_2$ incubator. The results obtained were as follows: Following vitrification with EFS, the post-thaw development of rabbit morulae to hatching blastocyst was significantly(P<0.05) higher in compacted stage(82.4%) than in early morular stage(60.0%). The post-thaw development of compacted morulae to hatching blastocyst was similarly high in vitrification with EFS(82.4%), EPG- I (85.0%) and in slow freezing with EPG- II (83.3%). Following vitrification with EPG- I, the post-thaw development of intact rabbit morulae to hatching blastocyst was similar as 78.0% and 85.0% in 1-step and 2-step post-thaw dilution, respectively. The post-thaw development of nuclear transplanted rabbit embryos of compacted morulae stage to hatching blastocyst was similarly 43.6% and 40.0% in vitrification with EPG- Iand slow freezing with EPG- II, respectively. These results indicated that the rabbit nuclear transplant and intact embryos of morulae stage could be well cryopreserved with either vitrification or slow freezing procedure.

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Effect of diluent variation on cryopreservation of large yellow croaker Larimichthys crocea

  • Lim, Han Kyu;Irfan, Zidni;Lee, Hyo Bin;Song, Ji Hoon;Lee, Yun Ho
    • Fisheries and Aquatic Sciences
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    • 제24권2호
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    • pp.63-77
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    • 2021
  • The aim of this research was to investigate different factors, including cryoprotective agents (CPAs), diluents, dilution ratios, equilibrium times, freezing rates, and thawing methods to optimize cryopreservation protocols for large yellow croaker (Larimichthys crocea). The parameters evaluated were sperm motility, sperm activity index (SAI), survival rate, and DNA damage. Different types of CPAs, such as dimethyl sulfoxide (DMSO), propylene glycol (PG), ethylene glycol (EG), methanol, and glycerol, were tested for sperm preservation. The highest motility, SAI, and survival rate were observed when EG was used. Different diluents such as Stein's solution, Hank's balanced salt solution, marine fish Ringer's solution, artificial seminal plasma (ASP) of small yellow croaker, and Cortland solution were investigated. The highest post-thaw motility was observed upon using ASP as the diluent. Different concentrations of EG were then mixed with ASP to identify the optimal EG concentration. Experimental results showed that the motility (70.33 ± 1.20%), SAI (5), and survival rate (78.30 ± 0.42%) of post-thaw sperm were optimum when 10% EG and ASP were used as the CPA and diluent of cryopreservation, respectively. Post-thaw sperm motility was high at equilibration times below 150 s and at an optimum dilution ratio of 1:1 (sperm: CPA + diluent) and was not significantly different compared with fresh sperm motility. The freezing rate was found to be slow below -10℃/min. The thawing temperature of 45℃ was identified as ideal. The percentage of tail DNA in post-thaw sperm at 10% EG and ASP was also investigated and was found to have more significant DNA damage than that in fresh sperm but significantly lower damage than that in post-thaw sperm at EG concentrations of 5%, 15%, and 20% (p < 0.05). The cryopreservation protocols obtained in this study will be useful in large yellow croaker hatcheries.

Effects of Contrast Agent Concentration on the Signal Intensity and Turbo Factor of TSE and Slice-selective IR in T1-weighted Contrast Imaging

  • Han, Yong Soo;Lee, Soo Chul;Lee, Dong Yong;Choi, Jiwon;Lee, Jong Woong;Kweon, Dae Cheol
    • Journal of Magnetics
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    • 제21권1호
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    • pp.115-124
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    • 2016
  • The present study analyzes T1 TSE and T1 slice sel. IR (dark_fluid) signal strength according to the degree of gadolinium contrast agent dilution and analyzes the turbo factors with regard to changes in the maximum and overall signal strength to study correlations between changes and signal-to-noise ratios (SNRs) and compare peak-to-peak SNR (PSNR) enhancement in order to improve the quality of T1-weighted images. Enhancement TR (600 msec) evaluated to determine the T1 TSE turbo factor and obtain the maximum signal strength, T1WI were used sequentially to experiment with turbo factors_1-4. T1 slice sel. IR (dark-fluid) was used to sequentially test turbo factors_2-5 but not turbo factor_1 at a TR (1500 msec) and compare data at an increase in T1 of 900 msec. The T1 TSE was reduced according to the contrast agent concentration. Phantom signal strength increased, whereas turbo factors_1-4 exhibited maximum signal strength at a concentration of 3 mmol, followed by a gradual decrease. In the turbo factors_2-5, the signal strength increased sharply to maximum signal strength at 0.7 mmol, followed by a reduction. T1 TSE had a greater maximum signal strength than did T1 slice sel. IR (dark_fluid). A comparison of SNR found that T1 TSE imaging was superior (33.3 dB) in turbo factor_1 and T1 slice sel. IR (dark_fluid) was highest (33.9 dB) at turbo factor_5. A PSNR comparison analysis was not sufficient to distinguish between the images obtained with both techniques at 30 dB or higher under all experimental conditions.

멀티패스 레이저 클래딩에 있어서 중첩률의 기준에 따른 클래드 층의 특성 비교 (Comparison of clad layer characteristics with overlapping criterion in multi pass laser cladding)

  • 김종도;이은진;황준구
    • Journal of Advanced Marine Engineering and Technology
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    • 제40권9호
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    • pp.768-773
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    • 2016
  • 엔진 밸브 시트와 페이스는 엔진 성능에 영향을 미치므로 내마모성, 내열성 및 내식성이 요구된다. 이러한 특성을 갖는 표면층을 형성하기 위해 일반적으로 PTA 프로세스를 사용하고 있지만 넓은 열 영향부와 높은 모재 희석 등과 같은 문제가 발생한다. 이러한 단점을 개선한 레이저 클래딩은 희석률이 낮고 열 영향 및 열 변형을 최소화하므로 더욱 우수한 클래드 층을 형성할 수 있다. 하지만 레이저 빔의 특성상 넓은 면적을 클래딩 할 경우, 1 패스 클래드 층의 중첩이 불가피하다. 중첩률 기준을 빔 사이즈와 클래드 층 폭으로 나누어 멀티패스 클래드 층을 형성한 결과, 기준에 관계없이 중첩률이 증가할수록 클래드 층의 폭이 감소하고 높이가 증가하였다. 하지만 빔 사이즈 기준 중첩률 조건으로 형성된 멀티패스 클래드 층이 다른 기준보다 모재 희석이 감소하여 더욱 높은 경도 값을 나타내었다. 결론적으로, 중첩률 기준을 클래드 층 폭으로 할 경우, 클래드 층 형상에 영향을 주는 공정변수가 변할 때 마다 폭의 길이가 달라지기 때문에 빔 사이즈를 중심으로 중첩률을 정의하였다.