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Suppressive effects of Th2 cytokines expression and the signal transduction mechanism in MC/9 mast cells by flavonol derived from Ginkgo biloba leaves (비만세포에서 은행잎 플라보놀에 의한 Th2 Cytokine 발현 및 신호전달 억제 기전 효과)

  • Kwon, Hae-Young;Chung, Kyu-Jin;Cheong, Kwang-Jo
    • Journal of Digital Convergence
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    • v.13 no.8
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    • pp.503-514
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    • 2015
  • The effects of Flavonol contents from Ginkgo biloba leaf on anti-atopy activity have not rarely been verified. This study is to investigate the effects of flavonol on Th2 cytokine production in MC/9 mast cells. For this, flavonol was analyzed by ELISA and Real-time PCR. Analysis results showed that flavonol significantly suppressed production of Th2 cytokines(IL-13, MIP-1a) in a dose dependent manner. The mRNA expression of IL-4, IL-5, IL-13, TNF-a were effectively restrained by Flavonol at the concentration 25,50,$100{\mu}g/m{\ell}$. And decrease of expression of NFAT-1, c-jun protein was confirmed by western blot analysis. These results indicate that flavonol has effects of decreasing the Th2 cytokine production in the MC/9 mast cell causing inhibition of transcription factors such as NFAT-1, c-jun. Thus, we would like to brief that flavonol may have the applicability as therapeutic agent for atopic dermatitis.

Antimicrobial and Antioxidant Activity of Hot Water and Ethanol Extracts of Ricinus communis L. Leaves and Fruits (피마자(Ricinus communis L.) 잎과 열매의 열수(熱水) 및 에탄올 추출물의 항균 활성과 항산화 효능)

  • Park, Jang-Soon
    • Journal of Digital Convergence
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    • v.16 no.6
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    • pp.353-361
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    • 2018
  • RFW and RFE of castor fruit selected as part of the development of natural antimicrobials and antioxidants yielded 15.8% and 18.4% respectively. In the results of measuring the antimicrobial activity through paper disc method, the antimicrobial activity of castor fruits in ethanol extracts appeared. Especially, the activity was excellent in P. aeruginosa and S. aureus, and antimicrobial activity of C. was 1.5mm up to 16 hours. However, the proliferation of C. was observed again after 24 hours. In the MIC experiment results of RFE, S. aureus and P. aeruginosa showed 96% and 93% of antimicrobial activity, respectively. The DPPH radical scavenging activity of RLW and castor leaf ethanol extract showed $1.8{\pm}0.6%$ and $2.1{\pm}0.7%$ free radical scavenging activity at $1000({\mu}g/m{\ell})$. This study is expected to provide basic data for the development of antimicrobial agents and antioxidants using natural products.

A Construction of Web Application Platform for Detection and Identification of Various Diseases in Tomato Plants Using a Deep Learning Algorithm (딥러닝 알고리즘을 이용한 토마토에서 발생하는 여러가지 병해충의 탐지와 식별에 대한 웹응용 플렛폼의 구축)

  • Na, Myung Hwan;Cho, Wanhyun;Kim, SangKyoon
    • Journal of Korean Society for Quality Management
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    • v.48 no.4
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    • pp.581-596
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    • 2020
  • Purpose: purpose of this study was to propose the web application platform which can be to detect and discriminate various diseases and pest of tomato plant based on the large amount of disease image data observed in the facility or the open field. Methods: The deep learning algorithms uesed at the web applivation platform are consisted as the combining form of Faster R-CNN with the pre-trained convolution neural network (CNN) models such as SSD_mobilenet v1, Inception v2, Resnet50 and Resnet101 models. To evaluate the superiority of the newly proposed web application platform, we collected 850 images of four diseases such as Bacterial cankers, Late blight, Leaf miners, and Powdery mildew that occur the most frequent in tomato plants. Of these, 750 were used to learn the algorithm, and the remaining 100 images were used to evaluate the algorithm. Results: From the experiments, the deep learning algorithm combining Faster R-CNN with SSD_mobilnet v1, Inception v2, Resnet50, and Restnet101 showed detection accuracy of 31.0%, 87.7%, 84.4%, and 90.8% respectively. Finally, we constructed a web application platform that can detect and discriminate various tomato deseases using best deep learning algorithm. If farmers uploaded image captured by their digital cameras such as smart phone camera or DSLR (Digital Single Lens Reflex) camera, then they can receive an information for detection, identification and disease control about captured tomato disease through the proposed web application platform. Conclusion: Incheon Port needs to act actively paying.

Estimation of rice growth parameters by X-band radar backscattering data

  • Kim, Yi-Hyun;Hong, Suk-Young;Lee, Hoon-Yol
    • Proceedings of the KSRS Conference
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    • 2008.10a
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    • pp.324-327
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    • 2008
  • Microwave remote sensing has great potential, especially in monsoon Asia, since optical observations are often hampered by cloudy conditions. The radar backscattering characteristics of rice crop were investigated with a ground-based automatic scatterometer system. The system was installed inside a shelter in an experimental paddy field at the National Institute of Agricultural Science and Technology (NIAST) before transplanting. The rice cultivar was a kind of Japonica type, called Chuchung. The scatterometer system consists of X-band antennas, HP8720D vector network analyzer, RF cables, and a personal computer that controls frequency, polarization and data storage. This system automatically measures fully-polarimatric backscattering coefficients of rice crop every 10 minutes, accompanied by a digital camera that takes pictures in a fixed position with the same interval. The backscattering coefficients were calculated by applying a radar equation. Plant variables, such as leaf area index (LAI), biomass, plant height and weather conditions were measured periodically throughout the rice growth season. We have performed polarimetric decomposition of paddy data such as single, double and volume scattering to extract the scattering information effectively. We investigated the relationships between backscattering coefficients and the plant variables.

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Method and Case Study of Decision Tree for Content Design Education (콘텐츠 디자인교육을 위한 의사 결정 트리 활용 방법과 사례연구)

  • Kim, Sungkon
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.4
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    • pp.283-288
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    • 2019
  • In order to overcome the students' lack of information and experience, we developed a content planning tree that utilizes a decision tree. The content planning tree consists of a tree trunk creation step in which students select a theme and a story to develop, a parent branch generation step for selecting a category that can be developed based on the story, a child branch generation step for selecting the interesting "effect" method of producing the content effectively, a leaf generation step for selecting a multimedia expression 'element' to be visualized. The educational model was applied to game planning design and information visualization lectures, and provides examples of the categories, effects, and elements used in each lecture. The model was used for 145 team projects and the efficiency was confirmed by a step-by-step learning process.

Customer Acceptance Procedure for Clinac (21EX-Platinum)

  • Hong, Dong-Ki;Lee, Woo-Seok;Kwon, Kyung-Tae;Park, Kwang-Ho;Kim, Chung-Man
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.2
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    • pp.43-61
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    • 2004
  • Purpose : For qualify improvement in radiotherapy, it is important to set up and evaluate equipment (linac) accurately. In addition, technicians are needed to be fully aware of the equipment's detailed quality and its manual. Therefore, the result of ATP is evaluated and introduced, in order that the technicians are skilled by participating in quality assurance (QA) and understanding the quality of the equipment before clinical use. Method and Material : QA for LINAC 21EX (Varian, US) was done with suppliers its procedure was divided into radiation survey, mechanical test, radiation isocenter test, bean performance, dosimetry, and enhanced dynamic wedge and using X-omat film (Kodak), multidata, densitometer, and electrometer. QA of MLC (Millennium, 120 leaf) attached to LINAC and EPID (Portal vision) were done separately. Result : The leakage dose by survey meter was below the tolerance. In mechanical test, collimater, gantry, and couch rotation were less than 1mm, and the angles were ${\pm}0.1^{\circ}$ for digital and ${\pm}0.5^{\circ}$ for mechanical. The alignment test of the light field and crosshair were evaluated less than 1mm. The (a)symmetrical jaw field was less than ${\pm}0.5mm$. The radiation isocenter test using X-mat film was less than 1mm. The consistency of light field and radiation field was less than ${\pm}0.1mm$. PDD for photon energy was less than ${\pm}1\%$ and for electron energy of $90\%,\;80\%,\;50\%,\;and\;30\%$ were evaluated within the tolerance. Flatness for photon and electron energy was evaluated $2.3\%$ (tolerance $3\%$) and $3\%$ (tolerance $4.5\%$), respectively, and symmetry was $0.45\%$ (tolerance $2\%$) and $0.3\%$ (tolerance $2\%$), respectively. Dosimetry test for short term, MU setting, rep rate, and dose rate accuracy of photon and electron energy was within the tolerance depending on energy, MU, and gantry angle. Conclusion : Accuracy and safety for clinical use of Clinac 21EX was verified through customer acceptance procedure and the quality of the equipment was found out. These can reduce the difficulties in using the equipment. Furthermore, it is useful for clinically treatment of patients by technicians' active participations.

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Physical Properties or Jujube (Zizyphus jujuba miller) and Jujube Branches (대추 및 대추가지의 물리적 특성)

  • 민경선;이상우;허윤근;서정덕;맹성렬
    • Journal of Biosystems Engineering
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    • v.27 no.4
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    • pp.283-292
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    • 2002
  • Mechanical and physical properties of various parts of jujube (Zizyphus jojoba Miller) such as fruits, leaves, secondary branches, and leafy stems were measured and analyzed. The physical dimensions of the fruits were measured using a digital caliper, and the detachment force of the fruit and leafy stems was measured using a force gauge. The physical characteristics of the secondary branches such as the modulus of elasticity and the torsional rigidity were tested using a universal testing machine (UTM). The physical characteristics of leafy stems such as length and weight were also measured using a digital caliper and a digital scale, respectively. The detachment force of leafy stems and the area of the leaf also measured. The terminal velocities of the jujube fruits, leaves, and leafy stems were measured using a custom made terminal velocity experiment system. Diameter of the major and minor axis of the jujube fruit, weight of the fruit, and detachment force of the fruit stem was average of 32.02 mm, 23.92 mm. 10.0 ${\times}$ 10$\^$6/ ㎥, 8.99 g, and 5.43 N. respectively. The detachment forces of the jujube fruits increased and the force-to-weight ratio of the jujube fruits decreased as the weight of the jujube fruits increased. The modulus of elasticity of the secondary branches of the jujube was average of 7.01 ${\times}$ 10$\^$8/ N/㎡ and decreased as diameter of the secondary branches increased. The average torsional rigidity of the secondary jujube branches was 5.2 ${\times}$ 10$\^$-/ N/㎡, and the torsional rigidity decreased as the secondary branch diameter increased. The distribution of the torsional rigidity data associated with the diameter of the branches, however. widely scattered and it was difficult to find any relationship between the diameter of the branches and the torsional rigidity of tile branches. The weight of the leafy stems, number of loaves attached to the leafy stems, diameter of the stem side of the leafy stems, diameter of the leafy stem end was average or 0.7 g, 6.6 ea, 12.2 cm, 4.5 mm, and 2.7 mm, respectively. The major and minor axis of the .jujube loaves, area of leaves, weight of the leaves. and detachment force of the leaves was average of 5.7 cm, 3.3 cm, 12.98 cm$^2$, 0.20 g, and 4.39 N, respectively. The terminal velocity of the .jujube fruits increased as the weight of the fruits increased. The terminal velocity of the leafy stems, however, did not show a relationship with the weight of the leafy stems and the number of leaves attached to the leafy stem. The terminal velocity, however, slightly increased as the length of the leafy stems increased.

Entomopathogenic Fungi-mediated Pest Management and R&D Strategy (곤충병원성 진균을 활용한 해충 관리와 개발 전략)

  • Lee, Se Jin;Shin, Tae Young;Kim, Jong-Cheol;Kim, Jae Su
    • Korean journal of applied entomology
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    • v.61 no.1
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    • pp.197-210
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    • 2022
  • Entomopathogenic fungi can be used to control a variety of sucking and chewing insects, with little effect on beneficial insects and natural enemies. Approximately 170 entomopathogenic fungal insecticides have been registered and used worldwide, with the recent focus being on the mode of action and mechanism of insect-fungal interactions. During the initial period of research and development, the industrialization of entomopathogenic fungi focused on the selection of strains with high virulence. However, improvement in productivity, including securing resistance to environmental stressors, is a major issue that needs to be solved. Although conidia are the primary application propagules, efforts are being made to overcome the limitations of blastospores to improve the economic feasibility of the production procedure. Fungal transformation is also being conducted to enhance insecticidal activity, and molecular biology is being used to investigate functions of various genes. In the fungi-based pest management market, global companies are setting up cooperative platforms with specialized biological companies in the form of M&As or partnerships with the aim of implementing a tank-mix strategy by combining chemical pesticides and entomopathogenic fungi. In this regard, understanding insect ecology in the field helps in providing more effective fungal applications in pest management, which can be used complementary to chemicals. In the future, when fungal applications are combined with digital farming technology, above-ground applications to control leaf-dwelling pests will be more effective. Therefore, for practical industrialization, it is necessary to secure clear research data on intellectual property rights.

Quality Assurance of Multileaf Collimator Using Electronic Portal Imaging (전자포탈영상을 이용한 다엽시준기의 정도관리)

  • ;Jason W Sohn
    • Progress in Medical Physics
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    • v.14 no.3
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    • pp.151-160
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    • 2003
  • The application of more complex radiotherapy techniques using multileaf collimation (MLC), such as 3D conformal radiation therapy and intensity-modulated radiation therapy (IMRT), has increased the significance of verifying leaf position and motion. Due to thier reliability and empirical robustness, quality assurance (QA) of MLC. However easy use and the ability to provide digital data of electronic portal imaging devices (EPIDs) have attracted attention to portal films as an alternatives to films for routine qualify assurance, despite concerns about their clinical feasibility, efficacy, and the cost to benefit ratio. In this study, we developed method for daily QA of MLC using electronic portal images (EPIs). EPID availability for routine QA was verified by comparing of the portal films, which were simultaneously obtained when radiation was delivered and known prescription input to MLC controller. Specially designed two-test patterns of dynamic MLC were applied for image acquisition. Quantitative off-line analysis using an edge detection algorithm enhanced the verification procedure as well as on-line qualitative visual assessment. In conclusion, the availability of EPI was enough for daily QA of MLC leaf position with the accuracy of portal films.

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Development of Plant Phenology and Snow Cover Detection Technique in Mountains using Internet Protocol Camera System (무인카메라 기반 산악지역 식물계절 및 적설 탐지 기술 개발)

  • Keunchang, Jang;Jea-Chul, Kim;Junghwa, Chun;Seokil, Jang;Chi Hyeon, Ahn;Bong Cheol, Kim
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.24 no.4
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    • pp.318-329
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    • 2022
  • Plant phenology including flowering, leaf unfolding, and leaf coloring in a forest is important to understand the forest ecosystem. Temperature rise due to recent climate change, however, can lead to plant phenology change as well as snowfall in winter season. Therefore, accurate monitoring of forest environment changes such as plant phenology and snow cover is essential to understand the climate change effect on forest management. These changes can monitor using a digital camera system. This paper introduces the detection methods for plant phenology and snow cover at the mountain region using an unmanned camera system that is a way to monitor the change of forest environment. In this study, the Automatic Mountain Meteorology Stations (AMOS) operated by Korea Forest Service (KFS) were selected as the testbed sites in order to systematize the plant phenology and snow cover detection in complex mountain areas. Multi-directional Internet Protocol (IP) camera system that is a kind of unmanned camera was installed at AMOS located in Seoul, Pyeongchang, Geochang, and Uljin. To detect the forest plant phenology and snow cover, the Red-Green-Blue (RGB) analysis based on the IP camera imagery was developed. The results produced by using image analysis captured from IP camera showed good performance in comparison with in-situ data. This result indicates that the utilization technique of IP camera system can capture the forest environment effectively and can be applied to various forest fields such as secure safety, forest ecosystem and disaster management, forestry, etc.