• Title/Summary/Keyword: Digital Inclusion

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Incidentally Detected Adenocarcinoma Prostate in Transurethral Resection of Prostate Specimens: a Hospital Based Study from India

  • Varghese, Jophy;Kuruvilla, Priya Mariam;Mehta, Nisarg;Rathore, Ranjeet Singh;Babu, Manas;Bansal, Devesh;Pillai, Biju;Sam, Mohan P;Krishnamorthy, H
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.2255-2258
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    • 2016
  • Background: Awareness about prostate cancer has increased in the community, and prostate cancer screening examinations, including prostate specific antigen (PSA) assays, are now widely available. Prior to the PSA era, up to 27% of prostate cancers were detected incidentally at the time of transurethral resection of prostate (TURP). After PSA testing became widely available, the incidence of incidentally detected carcinoma prostate in TURP specimens without prior diagnosis reduced to 5-13%. However, the incidence of incidentally detected carcinoma prostate has been reported to vary across the globe since various factors can influence the identification of this malignancy in TURP specimens. In this paper, we focus on rates of incidentally detected prostate cancer in TURP specimens in our hospital and correlate it with various parameters. Materials and Methods: This retrospective study of histopathological findings of biopsy specimens was conducted for patients undergoing TURP during a period of 5 years from April 2010. The inclusion criteria were patients diagnosed with benign prostatic hyperplasia (BPH) (digital rectal examination (DRE) not showing any abnormally hard areas and normal age adjusted PSA values). Patients with elevated PSA, abnormal DRE, documented urinary tract infection and proved adenocarcinoma prostate (CaP) were excluded from the study. The total weight of prostatectomy specimen, occurrence of carcinoma prostate in the chips, percentage of total tissue resected showing malignancy and Gleason's scores were recorded. Results: A total of 597 patients belonging to the inclusion criteria were studied. The incidence of occult CaP in the study group was 5.2 % (31/597). Out of these, 8 belonged to T1a and 23 belonged to T1b stages. The age group 70 - 79 years had the maximum incidence of occult CaP. It was observed that the clinical grading of prostate did not have a bearing on the incidence of occult CaP whereas the weight of resected specimen correlated with the incidence of CaP. The incidence of occult CaP was greater with low volume prostates (<20 g). (P=0.15). Conclusions: The rate of incidentally detected adenocarcinoma prostate in patients undergoing TURP for clinically diagnosed BPH was found to be only 5.2 % in our study which is low when compared with similar studies done elsewhere. The age of the patient and weight of the resected specimen correlated with incidence of occult prostate cancer. The clinical grading of prostate by DRE however, demonstrated no correlation.

Automated Areal Feature Matching in Different Spatial Data-sets (이종의 공간 데이터 셋의 면 객체 자동 매칭 방법)

  • Kim, Ji Young;Lee, Jae Bin
    • Journal of Korean Society for Geospatial Information Science
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    • v.24 no.1
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    • pp.89-98
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    • 2016
  • In this paper, we proposed an automated areal feature matching method based on geometric similarity without user intervention and is applied into areal features of many-to-many relation, for confusion of spatial data-sets of different scale and updating cycle. Firstly, areal feature(node) that a value of inclusion function is more than 0.4 was connected as an edge in adjacency matrix and candidate corresponding areal features included many-to-many relation was identified by multiplication of adjacency matrix. For geometrical matching, these multiple candidates corresponding areal features were transformed into an aggregated polygon as a convex hull generated by a curve-fitting algorithm. Secondly, we defined matching criteria to measure geometrical quality, and these criteria were changed into normalized values, similarity, by similarity function. Next, shape similarity is defined as a weighted linear combination of these similarities and weights which are calculated by Criteria Importance Through Intercriteria Correlation(CRITIC) method. Finally, in training data, we identified Equal Error Rate(EER) which is trade-off value in a plot of precision versus recall for all threshold values(PR curve) as a threshold and decided if these candidate pairs are corresponding pairs or not. To the result of applying the proposed method in a digital topographic map and a base map of address system(KAIS), we confirmed that some many-to-many areal features were mis-detected in visual evaluation and precision, recall and F-Measure was highly 0.951, 0.906, 0.928, respectively in statistical evaluation. These means that accuracy of the automated matching between different spatial data-sets by the proposed method is highly. However, we should do a research on an inclusion function and a detail matching criterion to exactly quantify many-to-many areal features in future.

Digital Replantation in Industrial Punch Injuries (천공 펀치 기계에 의한 수지 절단부의 재접합술)

  • Lee, Kyu-Cheol;Lee, Dong-Chul;Kim, Jin-Soo;Ki, Sae-Hwi;Roh, Si-Young;Yang, Jae-Won
    • Archives of Reconstructive Microsurgery
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    • v.19 no.1
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    • pp.12-20
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    • 2010
  • Purpose: Industrial punch accidents involving fingers cause segmental injuries to tendons and neurovascular bundles. Although multiple-level segmental amputations are not replanted to regain function, most patients with an amputated finger want to undergo replantation for cosmetic as much as functional reason. The authors describe four cases of digital amputation by an industrial punch that involved the reinstatement of the amputated finger involving a joint and neurovascular bundle. Amputated segments were replanted to restore amputated surfaces and distal segments. Methods: A single institution retrospective review was performed. Inclusion criteria of punch injuries requiring replantation were applied to patients of all demographic background. Injury extent (size, tissue involvement), operative intervention, pre- and postoperative hand function were recorded. Result: Four cases of amputations were treated at our institute from 2004 to 2008 from industrial punch machine injury. Average patient age was 32.5 years (25~39 years) and there were three males and one female. Sizes of amputated segments ranged from $1.0{\times}1.0{\times}1.2\;cm^3$ to $3{\times}1.5{\times}1.6\;cm^3$. Tenorrhaphy was conducted after fixing fractured bone of the amputated segments with K-wire. Proximal and distal arteries and veins were repaired using the through & through method. The average follow-up period was thirteen months (2~26 months), and all replanted cases survived. Osteomyelitis occurred in one case, skin grafting after debridement was performed in two cases. Because joints were damaged in all four cases, active ranges of motion were much limited. However, a secondary tendon graft enhanced digit function in two cases. The two-point discrimination test showed normal values for both static and dynamic tests for three cases and 9 mm and 15 mm by dynamic and static testing, respectively, in one case. Conclusion: Though amputations from industrial punch machines are technically challenging to replant, our experience has shown it to be a valid therapy. In cases involving punch machine injury, if an amputated segment is available, the authors recommend that replantation be considered for preservation of finger length, joint mobility, and overall functional recovery of the hand.

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Investigation on the Flexural and Shear Behavior of Fiber Reinforced UHSC Members Reinforced with Stirrups (전단철근과 강섬유로 보강된 초고강도 콘크리트 부재의 휨 및 전단 거동에 관한 연구)

  • Yuh, Ok-Kyung;Ji, Kyu-Hyun;Bae, Baek-Il
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.23 no.7
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    • pp.152-163
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    • 2019
  • In this paper, effect of steel fiber inclusion, compressive strength of matrix, shear reinforcement and shear span to depth ratio on the flexural behavior of UHPFRC(Ultra High Performance Fiber Reinforced Concrete) were investigated with test of 10-UHPFRC beam specimens. All test specimens were subjected to the flexural static loading. It was shown that steel fiber significantly improve the shear strength of UHPFRC beams. 2% volume fraction of steel fiber change the mode of failure from shear failure to flexural failure and delayed the failure of compressive strut with comparatively short shear span to depth ratio. UHPFRC beams without steel fiber had a 45-degree crack angle and fiber reinforced one had lower crack angle. Shear reinforcement contribution on shear strength of beams can be calculated by 45-degree truss model with acceptable conservatism. Using test results, French and Korean UHPFRC design recommendations were evaluated. French recommendation have shown conservative results on flexural behavior but Korean recommendation have shown overestimation for flexural strength. Both recommendations have shown the conservatism on the flexural ductility and shear strength either.

Mandibular arch orthodontic treatment stability using passive self-ligating and conventional systems in adults: A randomized controlled trial

  • Rahman, Norma Ab;Wey, Mang Chek;Othman, Siti Adibah
    • The korean journal of orthodontics
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    • v.47 no.1
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    • pp.11-20
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    • 2017
  • Objective: This randomized controlled trial aimed to compare the stability of mandibular arch orthodontic treatment outcomes between passive self-ligating and conventional systems during 6 months of retention. Methods: Forty-seven orthodontic patients with mild to moderate crowding malocclusions not requiring extraction were recruited based on inclusion criteria. Patients (mean age $21.58{\pm}2.94years$) were randomized into two groups to receive either passive self-ligating ($Damon^{(R)}$ 3MX, n = 23) or conventional system (Gemini MBT, n = 24) orthodontic treatment. Direct measurements of the final sample comprising 20 study models per group were performed using a digital caliper at the debonding stage, and 1 month, 3 months, and 6 months after debonding. Paired t-test, independent t-test, and non-parametric test were used for statistical analysis. Results: A significant increase (p < 0.01) in incisor irregularity was observed in both self-ligating and conventional system groups. A significant reduction (p < 0.01) in second interpremolar width was observed in both groups. Mandibular arch length decreased significantly (p = 0.001) in the conventional system group but not in the self-ligating system group. A similar pattern of stability was observed for intercanine width, first interpremolar width, intermolar width, and arch depth throughout the 6-month retention period after debonding. Comparison of incisor irregularity and arch dimension changes between self-ligating system and conventional system groups during the 6 months were non-significant. Conclusions: The stability of treatment outcomes for mild to moderate crowding malocclusions was similar between the self-ligating system and conventional system during the first 6 months of retention.

A Systematic Review of Bee Venom Acupuncture for Ankle Sprain (족관절 염좌의 봉독 약침 치료에 대한 체계적 문헌 고찰)

  • Gu, Ji-Hyang;Li, Yu-Chen;Jo, Dong-Chan;Lee, Eun-Jung
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.3
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    • pp.55-66
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    • 2018
  • Objectives To evaluate the evidence supporting the effectiveness of bee venom acupuncture for ankle sprain. Methods We conducted search across 11 electronic databases (Pubmed, EMBASE, Cochrane CENTRAL [CENTRAL], KoreaMed, Kmbase, Koreanstudies Information Service System [KISS], National Digital Science Library [NDSL], Korea Institute of Science and Technology Information [KISTI], China National Knowledge Infrastructure [CNKI], Wanfang and Chinese Scientific Journals Database [VIP] database) to find clinical trials that used bee venom acupuncture as treatment for ankle sprain. The methodological quality of randomized controlled clinical trials (RCTs) were assessed using the Cochrane Risk of Bias (RoB) tool, while non-randomized controlled clinical trials (NRCTs) were assessed using the Cochrane Risk of Bias Assessment tool for Non-randomized Study (RoBANS) tool. Results Four RCTs and one nRCT met our inclusion criteria. Almost studies showed that bee venom acupuncture has positive effect on ankle sprain. 4 studies of same intervention and control included in the meta-analysis. When comparing bee venom acupuncture and acupuncture with acupuncture, the effect size of standardized mean difference (SMD) was -0.19 (95% confidence interval [CI]: -1.95~1.56, Z=0.55, p=0.83). And when comparing bee venom acupuncture with acupuncture, the effect size of SMD was -0.17 (95% CI: -0.65~0.31, Z=0.71, p=0.48). Conclusions Although our systematic review found encouraging but limited evidence of bee venom acupuncture for ankle sprain, most of the studies included in the analysis were evaluated as methodologically high risk of bias. From now on further well-designed RCTs should be encouraged.

Correlation Between Muscle Strength, Pulmonary Function and Respiratory Muscle in Children with Cerebral Palsy (뇌성마비 아동의 근력과 호흡기능의 상관관계)

  • Shin, Seung-Oh;Kim, Nan-Su
    • Journal of the Korean Society of Physical Medicine
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    • v.11 no.2
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    • pp.123-130
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    • 2016
  • PURPOSE: This study was conducted to determine correlations between grip and lower limb muscle strength and pulmonary function and respiratory muscle in children with cerebral palsy. METHODS: Subjects were 17 children with cerebral palsy. Inclusion criteria for participation were having GMFCS from I to III grade and ability to independently blow into a spirometer. Pulmonary function and respiratory muscle were measured with a spirometer. All subjects performed maximal expiratory flow maneuvers using a spirometer in order to determine their forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF) and FEV1/FVC, and maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP). Muscle strength was measured in terms of grip strength and lower limb muscle strength in terms of knee extension strength with a dynamometer and manual digital muscle tester respectively. Data were analyzed using Person product correlation. RESULTS: Grip strength significantly positively correlated with FVC (r=0.95, p<0.01), FEV1 (r=0.95, p<0.01), PEF (r=0.84, p<0.01), MIP (r=0.65, p<0.01) MEP (r=0.71, p<0.01) and lower limb strength with FVC (r=0.72, p<0.01), FEV1 (r=0.69, p<0.01), PEF (r=0.54, p<0.05), and MEP (r=0.69, p<0.01). CONCLUSION: Grip and lower limb muscle strengths of children with cerebral palsy were positively correlated pulmonary function and respiratory muscle.

Hands-On Experience-Based Comprehensive Curriculum for Microelectronics Manufacturing Engineering Education

  • Ha, Taemin;Hong, Sang Jeen
    • Transactions on Electrical and Electronic Materials
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    • v.17 no.5
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    • pp.280-288
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    • 2016
  • Microelectronic product consumers may already be expecting another paradigm shift with smarter phones over smart phones, but the current status of microelectronic manufacturing engineering education (MMEE) in universities hardly makes up the pace for such a fast moving technology paradigm shift. The purpose of MMEE is to educate four-year university graduates to work in the microelectronics industry with up-to-date knowledge and self-motivation. In this paper, we present a comprehensive curriculum for a four-year university degree program in the area of microelectronics manufacturing. Three hands-on experienced-based courses are proposed, along with a methodology for undergraduate students to acquire hands-on experience, towards integrated circuits (ICs) design, fabrication and packaging, are presented in consideration of manufacturing engineering education. Semiconductor device and circuit design course for junior level is designed to cover how designed circuits progress to micro-fabrication by practicing full customization of the layout of digital circuits. Hands-on experienced-based semiconductor fabrication courses are composed to enhance students’ motivation to participate in self-motivated semiconductor fab activities by performing a series of collaborations. Finally, the Microelectronics Packaging course provides greater possibilities of mastered skillsets in the area of microelectronics manufacturing with the fabrication of printed circuit boards (PCBs) and board level assembly for microprocessor applications. The evaluation of the presented comprehensive curriculum was performed with a students’ survey. All the students responded with “Strongly Agree” or “Agree” for the manufacturing related courses. Through the development and application of the presented curriculum for the past six years, we are convinced that students’ confidence in obtaining their desired jobs or choosing higher degrees in the area of microelectronics manufacturing was increased. We confirmed that the hypothesis on the inclusion of handson experience-based courses for MMEE is beneficial to enhancing the motivation for learning.

Study on Tribological Characteristics of Machine Component in Boundary Lubrication (경계윤활에서 기계 부품 소재의 트라이볼로지적 특성에 관한 연구)

  • Kim, Myeong-Gu;Seo, Kuk-Jin;Nam, Jahyun;Kim, Dae-Eun
    • Tribology and Lubricants
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    • v.35 no.6
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    • pp.356-361
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    • 2019
  • The friction and wear between machine components directly influence the energy loss and failure in various machines. Therefore, there is always a demand for finding methods to reduce friction and wear. Of the possible methods, lubrication is a widely used method for reducing friction and wear. In the case of lubrication, it is important to analyze the tribological behavior in the boundary lubrication because most of friction and wear occurs in the boundary lubrication regime. Cast iron has been regarded as a good material for industrial applications due to the excellent mechanical properties and high productivity. Especially, nodular cast iron is a material that shows better mechanical properties and wear-resistance compared with cast iron due to inclusion of spheroidal graphite. In this work, we investigated the tribological characteristics of nodular cast iron with respect to different counter parts in boundary lubrication regime. Sliding tests were conducted with SUJ2, ZrO2, Si3N4 balls as counter parts using a pin-on-disk type tribotester. The results showed different friction and wear behaviors with different counter parts. The case of ZrO2 showed the lowest wear rate in specimen and no significant ball wear. In case of SUJ2, it showed similar wear rate with ZrO2 case in specimen and the highest friction coefficient. The case of Si3N4 showed the lowest friction coefficient, 33% lower than the case of SUJ2. It showed 16.9 times larger wear rate in specimen and 43% larger wear rate in ball compared to that of the SUJ2 case.

A Study on Application Method of Ontologies for Efficient Semantic-based Search of Copyrighted Works (저작물의 의미 기반 검색을 위한 온톨로지 적용 방안 연구)

  • Yoo, Min-Kyu;Kim, Yoon-Ho
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.5
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    • pp.19-28
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    • 2015
  • Korea Digital Copyright Exchange of Korea Copyright Commission runs and manages copyrighted works and copyright license agreement, as well as assigns Integrated Copyright Number(ICN) to copyrighted works, also offers copyrighted works searching service. Keyword-based searching method based on ICN metadata provides results depending on the inclusion of metadata keyword. However, keyword-based searching method has limitations that cannot provide exact results that users need. Therefore, the essential method of offering exact result is needed. In this paper, we propose the semantic-based searching method about copyrighted works to increase the accuracy of searching results by extending ICN matadata to ontology, and implement the ontology of copyrighted works by defining relation and semantics about metadata elements. In order to compare semantic-based searching based on the ontology of copyrighted works with keyword-based searching method, the search results of each method according to 5 scenarios are presented and the accuracy of each method is compared.