• 제목/요약/키워드: Digital Health

검색결과 2,318건 처리시간 0.029초

Elevated Plus-Maze를 이용한 현삼의 항불안 효과 : GABA 신경계와의 관련성 연구 (Anxiolytic-like Effects of Scrophularia buergeriana Miquel Using the Elevated Plus-Maze in Mice : Involvement of GABAergic Nervous System)

  • 최윤희;정지욱
    • 동의생리병리학회지
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    • 제24권3호
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    • pp.476-483
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    • 2010
  • The present study was performed to investigate the putative anxiolytic-like effects of the aqueous extract of the roots of Scrophularia buergeriana (SB-W) using elevated plus-maze (EPM) and hole-board apparatus in mice. SB-W was orally administered at doses of 50, 100, 200 or 400 mg/kg to ICR mice, 1 h before the behavioral evaluation. Control group were administered with an equal volume of saline, and positive control group with buspirone (2 mg/kg, i.p.). The administration of SB-W significantly increased the percentage of time spent in open arms and entries into the open arms of the EPM compared with saline-treated control group (P < 0.05). Futhermore, those anxiolytic-like activities of SB-W were antagonized by flumazenil (a $GABA_A$ antagonist, 10 mg/kg), but not by WAY-100635 (a 5-$HT_{1A}$ antagonist, 0.3 mg/kg). Moreover, there were no changes in the locomotor activity and myorelaxant effects in any group compared with saline-treated control group. In the hole-board test, the administration of SB-W (200 and 400 mg/kg) significantly increased the number of head-dipping compared with saline-treated control group (P < 0.05). Therefore, these findings suggest that Scrophularia buergeriana promotes the anxiolytic-like activity mediated by GABAergic nervous system in mice.

Transparent and Flexible All-Organic Multi-Functional Sensing Devices Based on Field-effect Transistor Structure

  • Trung, Tran Quang;Tien, Nguyen Thanh;Seol, Young-Gug;Lee, Nae-Eung
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2011년도 제40회 동계학술대회 초록집
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    • pp.491-491
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    • 2011
  • Transparent and flexible electronic devices that are light-weight, unbreakable, low power consumption, optically transparent, and mechanical flexible possibly have great potential in new applications of digital gadgets. Potential applications include transparent displays, heads-up display, sensor, and artificial skin. Recent reports on transparent and flexible field-effect transistors (tf-FETs) have focused on improving mechanical properties, optical transmittance, and performances. Most of tf-FET devices were fabricated with transparent oxide semiconductors which mechanical flexibility is limited. And, there have been no reports of transparent and flexible all-organic tf-FETs fabricated with organic semiconductor channel, gate dielectric, gate electrode, source/drain electrode, and encapsulation for sensor applications. We present the first demonstration of transparent, flexible all-organic sensor based on multifunctional organic FETs with organic semiconductor channel, gate dielectric, and electrodes having a capability of sensing infrared (IR) radiation and mechanical strain. The key component of our device design is to integrate the poly(vinylidene fluoride-triflouroethylene) (P(VDF-TrFE) co-polymer directly into transparent and flexible OFETs as a multi-functional dielectric layer, which has both piezoelectric and pyroelectric properties. The P(VDF-TrFE) co-polumer gate dielectric has a high sensitivity to the wavelength regime over 800 nm. In particular, wavelength variations of P(VDF-TrFE) molecules coincide with wavelength range of IR radiation from human body (7000 nm ~14000 nm) so that the devices are highly sensitive with IR radiation of human body. Devices were examined by measuring IR light response at different powers. After that, we continued to measure IR response under various bending radius. AC (alternating current) gate biasing method was used to separate the response of direct pyroelectric gate dielectric and other electrical parameters such as mobility, capacitance, and contact resistance. Experiment results demonstrate that the tf-OTFT with high sensitivity to IR radiation can be applied for IR sensors.

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항공기 엔진제어시스템 인증기술 개발 (A Study on Certification of Electronic Engine Controls)

  • 이강이;한상호;진영권;이상준;김귀순
    • 한국항공우주학회지
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    • 제33권1호
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    • pp.104-109
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    • 2005
  • 항공기용 가스터빈엔진에 사용되고 있는 전자식 엔진제어장치는 연료 절약 및 성능 향상을 목적으로 개발되어, 최근에는 엔진의 신뢰성 향상을 위한 고장진단 기능을 갖춘 전자동디지털식 엔진제어장치로 발전하였다. 이와 같은 기술의 발전으로 과거와는 다른 새로운 개념의 엔진제어장치에 대한 인증기술 개발의 필요성이 증대되고 있다. 전자식 엔진제어장치에 대한 설계 및 인증에서 고려되어야 하는 사항으로 전원 공급, 입력 데이터, 고장 모드, 소프트웨어 확인 및 검증, 그리고 낙뢰의 영향 등을 들 수 있다. 본 연구에서는 전자식 엔진제어장치에 대한 설계 고려사항과 인증 기법을 분석하였고, 이를 바탕으로 국내 감항기술기준의 관련 요구조건을 정립할 수 있도록 하였다.

Cephalometric landmark variability among orthodontists and dentomaxillofacial radiologists: a comparative study

  • Durao, Ana Paula Reis;Morosolli, Aline;Pittayapat, Pisha;Bolstad, Napat;Ferreira, Afonso P.;Jacobs, Reinhilde
    • Imaging Science in Dentistry
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    • 제45권4호
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    • pp.213-220
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    • 2015
  • Purpose: The aim this study was to compare the accuracy of orthodontists and dentomaxillofacial radiologists in identifying 17 commonly used cephalometric landmarks, and to determine the extent of variability associated with each of those landmarks. Materials and Methods: Twenty digital lateral cephalometric radiographs were evaluated by two groups of dental specialists, and 17 cephalometric landmarks were identified. The x and y coordinates of each landmark were recorded. The mean value for each landmark was considered the best estimate and used as the standard. Variation in measurements of the distance between landmarks and measurements of the angles associated with certain landmarks was also assessed by a subset of two observers, and intraobserver and interobserver agreement were evaluated. Results: Intraclass correlation coefficients were excellent for intraobserver agreement, but only good for interobserver agreement. The least reliable landmark for orthodontists was the gnathion (Gn) point (standard deviation [SD], 5.92 mm), while the orbitale (Or) was the least reliable landmark (SD, 4.41 mm) for dentomaxillofacial radiologists. Furthermore, the condylion (Co)-Gn plane was the least consistent (SD, 4.43 mm). Conclusion: We established that some landmarks were not as reproducible as others, both horizontally and vertically. The most consistently identified landmark in both groups was the lower incisor border, while the least reliable points were Co, Gn, Or, and the anterior nasal spine. Overall, a lower level of reproducibility in the identification of cephalometric landmarks was observed among orthodontists.

영상 처리 기법을 이용한 흡연이 폐 기능에 미치는 영향 분석 (Influence Analysis on the Lung Function due to Smoking Using Image Processing Techniques)

  • 김봉현;조동욱
    • 한국통신학회논문지
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    • 제37권7C호
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    • pp.610-618
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    • 2012
  • 본 논문에서는 영상 처리 기술을 이용한 색상 분석 프로그램을 개발, 적용하여 흡연이 폐 기능에 미치는 영향을 분석하였다. 즉, 한의학의 진단 이론인 망진을 기반으로 폐와 우측 뺨 영역이 연관되어 있으며 폐 기능이 약해지면 백색에 가까워진다는 내용을 IT기술인 영상 처리 기법을 적용하여 흡연에 따른 얼굴 색상의 변화를 비교, 분석하는 연구를 수행하였다. 이를 위해 20대 남성 피실험자 15명을 대상으로 흡연 전과 후의 우측 뺨 영역의 색상을 추출, 분석하였으며 Lab 색체계에서 a값과 b값이 흡연에 의해 어떻게 변하는지를 분석하고자 하며 이를 기반으로 개인별 편차가 반영된 개인맞춤형 건강관리 시스템을 구축하고자 한다. 실험 결과 흡연에 따라 우측 뺨 영역의 색상이 흡연량에 비례하여 백색에 가까워졌으며 이는 흡연이 폐 기능에 악영향을 미치는 것으로 분석할 수 있었다.

남녀 대학생들의 수직착지 시 성에 따른 무릎 외반각도의 차이 (Gender Differences of Knee Valgus Angle during Vertical Drop Landing in College Students)

  • 이충휘;박소연;유원규
    • 한국전문물리치료학회지
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    • 제12권1호
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    • pp.28-35
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    • 2005
  • The purpose of this study was to determine whether gender differences existed in knee valgus kinematics in college students when performing a vertical drop landing. The hypothesis of this study was that females would demonstrate greater knee valgus motion. These differences in knee valgus motion may be indicative of decreased dynamic knee joint control in females. This study compared the initial knee valgus angle and maximum knee valgus angle at the instant of impact on vertical drop landings between healthy men and women. In this study, 60 participants (30 males, 30 females) dropped from a height of 43 cm. A digital camera and two-dimensional video motion analysis software were used to analyze the kinematic data. There was significant difference in the mean knee valgus angle at initial contact landing between the two groups (Mean=$7.88^{\circ}$, SD=$4.24^{\circ}$ in males, Mean=$12.93^{\circ}$, SD=$2.89^{\circ}$ in females). The range of knee valgus angle on landing (Mean=$3.25^{\circ}$, SD=$5.72^{\circ}$ in males, Mean=$11.44^{\circ}$, SD=$6.39^{\circ}$ in females) was differed significantly (p<.05). The maximal angle of knee valgus on landing (Mean=$10.91^{\circ}$, SD=$6.89^{\circ}$ in males, Mean=$24.25^{\circ}$, SD=$6.38^{\circ}$ in females) was also differed significantly (p<.05). The females landed with a larger range of knee valgus motion than the males and this might have increased the likelihood of a knee injury. The absence of dynamic knee joint stability may be responsible for increased rates of knee injury in females. No method for accurate and practical screening and identification of athletes at increased risk of ACL injury is currently available to target those individuals that would benefit from neuromuscular training before sports participation.

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복식 디자인에 표현된 의미적 열린 구조 (A Study on Meaning of Open Structure in Clothing Design)

  • 조애래;김영인
    • 복식
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    • 제56권9호
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    • pp.1-13
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    • 2006
  • The purpose of this study is to apply a concept of open structure to clothing design and to verify the characteristics found in the various types of clothing which has open structure. The literatures from various academic fields including philosophy, literature, social science, architecture, and fine arts are investigated to define the concept of openness and to analyze it from the perspectives both of the visual and of the moaning of openness. This paper is to identify the types and the characteristics of clothing by future intention, complexity, discontinuity of open structure. By closely examining fashion design after 1980s found in fashion collection publications and designer's websites, the results of this study are as follows: first, the concept of openness can be classified into two different levels, that is, visual and meaning, secondly, in clothing the concept of open structure is applied to the meaning side by future intention, by complexity and by discontinuity. Open structure through future Intention has new content and interpretation and must have the possibility of intelligence awakening, future guidance and basic contents. Open structure through complexity has secondary function exists concurrent with the shape key example is the smart clothes with the digital functions. It has functions of amusement, supplement and protective, and is future clothes which satisfies with health, welfare, desire of beauty. Open structure with discontinuity is clothes with dramatic changes in system, structures and states. Structure can be changed by silhouette, detail, or fabric, material, or dramatic and practical function as tools in terms of productions and environment. This study can help to formulate and to integrate the concept of open structure in clothing with various phases and enhance the value of clothes by showing an application of the concept of openness to the clothing in meaning level.

의료용 기능성 게임의 품질평가 요소 추출 (The Extraction of Quality Evaluation Elements for Medical Serious Game)

  • 윤선정;류미영
    • 한국컴퓨터정보학회논문지
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    • 제18권3호
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    • pp.19-26
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    • 2013
  • 최근에 의료용 기능성 게임의 긍정적 효과가 입증되면서 사용자를 위하여 품질평가가 중요한 이슈가 되었다. 품질평가는 객관적인 기준과 평가요소 개발이 중요하다. 기능성게임의 품질평가는 프로그램적인 기술적 영역과 콘텐츠적인 비기술적 영역으로 나누어 진행된다. 본 연구에서는 품질평가 모델 개발 프로세스에 따라 심리 치료게임과 헬스 재활 치료게임에 대해 비기술적인 영역의 품질평가 요소를 개발하였다. 두 종류의 의료용 게임에 각각 5가지의 평가 요소를 추출하고 타당성을 확보하기 위해 의료 전문가들의 인터뷰를 진행하였다. 추출된 요소는 적합도 검사를 실시하여 검증하였다. 두 집단에 대한 카이제곱검정 결과는 유의미한 차이가 없었다. 본 연구 결과는 의료용 기능성게임을 설계하고 개발하는데 활용할 수 있을 것으로 기대한다.

자동차 유통시스템의 고객만족도가 기업의 재무적 성과에 미치는 영향 (The Effects of Customer Satisfaction of Automobile Distribution System on Corporate Financial Performance)

  • 이원일
    • 유통과학연구
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    • 제6권1호
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    • pp.79-98
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    • 2008
  • 기업성과 평가는 일정기간동안 기업 활동의 결과로서 기업의 경쟁력 수준을 제시함과 동시에 미래 기업의 활동 방향에 대한 지침으로서 역할을 수행한다. 경영환경이 급속히 변화하는 지식정보사회에서 재무적인 측정지표에 근거한 성과측정은 그 효과성이 제한되어 있음을 부인할 수 없다. 그러나 재무지표의 비중을 너무 가볍게 여겨서는 안 될 것이다. 그 이유는 품질이나 고객만족 또는 혁신 등과 같은 기업 목표들은 매우 전략적이고 좋은 것이기는 하지만 이것들은 반드시 재무적인 성과로 연결이 되어야 하고 나아가 기업성과로 구체화되어야 하기 때문이다. 즉, 재무적 성과는 다른 관점의 성과들과 상호보완적이고 균형적인 관계를 유지해야 한다. 자동차 유통시스템의 고객만족도와 재무적 성과 사이에 차이가 있는지를 살펴본 결과 신뢰도, 고객충성도, 재구매의사 및 구전광고에서는 유의한 차이가 있는 것으로 나타났으며, 고객만족도와 재무적 성과 사이에 차이가 있는지를 살펴본 결과 재무적 성과 변수인 안정성, 성장성, 활동성에 유의한 차이가 있는 것으로 나타났다.

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Light transmittance of CAD/CAM ceramics with different shades and thicknesses and microhardness of the underlying light-cured resin cement

  • Jafari, Zahra;Alaghehmand, Homayoon;Samani, Yasaman;Mahdian, Mina;Khafri, Soraya
    • Restorative Dentistry and Endodontics
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    • 제43권3호
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    • pp.27.1-27.9
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    • 2018
  • Objectives: The aim of this in vitro study was to evaluate the effects of the thickness and shade of 3 types of computer-aided design/computer-aided manufacturing (CAD/CAM) materials. Materials and Methods: A total of 120 specimens of 2 shades (A1 and A3) and 2 thicknesses (1 and 2 mm) were fabricated using VITA Mark II (VM; VITA Zahnfabrik), IPS e.max CAD (IE; IvoclarVivadent), and VITA Suprinity (VS; VITA Zahnfabrik) (n = 10 per subgroup). The amount of light transmission through the ceramic specimens was measured by a radiometer (Optilux, Kerr). Light-cured resin cement samples (Choice 2, Bisco) were fabricated in a Teflon mold and activated through the various ceramics with different shades and thicknesses using an LED unit (Bluephase, IvoclarVivadent). In the control group, the resin cement sample was directly light-cured without any ceramic. Vickers microhardness indentations were made on the resin surfaces (KoopaPazhoohesh) after 24 hours of dark storage in a $37^{\circ}C$ incubator. Data were analyzed using analysis of variance followed by the Tukey post hoc test (${\alpha}=0.05$). Results: Ceramic thickness and shade had significant effects on light transmission and the microhardness of all specimens (p < 0.05). The mean values of light transmittance and microhardness of the resin cement in the VM group were significantly higher than those observed in the IE and VS groups. The lowest microhardness was observed in the VS group, due to the lowest level of light transmission (p < 0.05). Conclusion: Greater thickness and darker shades of the 3 types of CAD/CAM ceramics significantly decreased the microhardness of the underlying resin cement.