• 제목/요약/키워드: Diffusion outcomes

검색결과 60건 처리시간 0.031초

Proper Indication of Decompressive Craniectomy for the Patients with Massive Brain Edema after Intra-arterial Thrombectomy

  • Sang-Hyuk Im;Do-Sung Yoo;Hae-Kwan Park
    • Journal of Korean Neurosurgical Society
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    • 제67권2호
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    • pp.227-236
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    • 2024
  • Objective : Numerous studies have indicated that early decompressive craniectomy (DC) for patients with major infarction can be life-saving and enhance neurological outcomes. However, most of these studies were conducted by neurologists before the advent of intra-arterial thrombectomy (IA-Tx). This study aims to determine whether neurological status significantly impacts the final clinical outcome of patients who underwent DC following IA-Tx in major infarction. Methods : This analysis included 67 patients with major anterior circulation major infarction who underwent DC after IA-Tx, with or without intravenous tissue plasminogen activator. We retrospectively reviewed the medical records, radiological findings, and compared the neurological outcomes based on the "surgical time window" and neurological status at the time of surgery. Results : For patients treated with DC following IA-Tx, a Glasgow coma scale (GCS) score of 7 was the lowest score correlated with a favorable outcome (p=0.013). Favorable outcomes were significantly associated with successful recanalization after IA-Tx (p=0.001) and perfusion/diffusion (P/D)-mismatch evident on magnetic resonance imaging performed immediately prior to IA-Tx (p=0.007). However, the surgical time window (within 36 hours, p=0.389; within 48 hours, p=0.283) did not correlate with neurological outcomes. Conclusion : To date, early DC surgery after major infarction is crucial for patient outcomes. However, this study suggests that the indication for DC following IA-Tx should include neurological status (GCS ≤7), as some patients treated with early DC without considering the neurological status may undergo unnecessary surgery. Recanalization of the occluded vessel and P/D-mismatch are important for long-term neurological outcomes.

EDI의 확산요인과 성과에 관한 연구 (An Empirical Study on Determinants and Outcomes of Electronic Data Interchange Diffusion)

  • 최도원
    • 한국컴퓨터정보학회:학술대회논문집
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    • 한국컴퓨터정보학회 2010년도 제42차 하계학술발표논문집 18권2호
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    • pp.153-154
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    • 2010
  • 정보 통신망과 정보통신기기가 보급 확산되고 이들 기술의 발달을 바탕으로 전략적 차원에서 조직끼리 정보를 공유하는 조직간 시스템(Inter-organizational System : IOS)이 확산되고 있는데 그 대표적인 IOS 중의 하나가 바로 전자자료교환(EDI : electronic data interchange)이다. 본 논문에서는 EDI를 도입하고 있는 국내 기업들의 EDI 내 외부 확산정도에 영향을 미치는 EDI의 확산요인을 제시하고 이와 병행하여 EDI의 내 외부 확산정도에 따른 EDI의 조직성과를 규명한다. EDI를 내 외부적으로 확산시키기 위해서는 최고경영자의 EDI 사용에 대한 지원과 조직내 정보기술의 성숙이 필수적인 것으로 판명되었다. 또한 본 논문은 국내의 상항에 맞는 EDI의 확산요인을 제시함으로써 국내 기업들이 EDI를 좀 더 확산시킬 수 있는 데 기여하게 될 것이다.

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Modeling and Simulation of the Photocatalytic Treatment of Wastewater using Natural Bauxite and TiO2 doped by Quantum Dots

  • Becheikh, Nidhal;Eladeb, Aboulbaba;Ghazouani, Nejib
    • International Journal of Computer Science & Network Security
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    • 제22권6호
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    • pp.91-96
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    • 2022
  • The photocatalytic degradation of salicylic acid takes place in several stages involving coupled phenomena, such as the transport of molecules and the chemical reaction. The systems of transport equations and the photocatalytic reaction are numerically solved using COMSOL Mutiphysics (CM) simulation software. CM will make it possible to couple the phenomena of flow, the transport of pollutants (salicylic acid) by convection and diffusion, and the chemical reaction to the catalytic area (bauxite or TiO2 doped by nanoparticles). The simulation of the conversion rate allows to correctly fit the experimental results. The temporal simulation shows that the reaction reaches equilibrium after a transitional stage lasting over one minute. The outcomes of the study highlight the importance of diffusion in the boundary layer and the usefulness of injecting micro-agitation into the microchannel flow. Under such conditions, salicylic acid degrades completely.

간호관리학 실습에서의 근거기반간호 교육 적용: 결과평가와 확산 전략 (Implementation of Evidence Based Nursing Education into Nursing Management Clinical Practicum: Outcome Evaluation and Diffusion Strategies)

  • 박명화
    • 간호행정학회지
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    • 제19권1호
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    • pp.39-47
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    • 2013
  • Purpose: This practice study was done to describe the process and outcomes of application of Evidence Based Nursing (EBN) Education to nursing management clinical practicum and suggest strategies to diffuse EBN into nursing management education. Methods: Education on the evidence based nursing management process was provided to 65 senior nursing students from a university. Nursing management clinical practicum integrated with EBN. The setting was a five full day-clinical practicum. Group and individual training on EBN process with lectures, small group discussions, conferences, and educational prescription were provided. Outcomes were analyzed using paired t test for 65 participants. Results: Evidence based nursing competency increased significantly showing improvement in understanding EBN, formulating clinical question, searching & classifying the evidence, recognizing level of evidence, considering patient preference, and evaluating outcomes. Nursing students' access and use of evidence based information resource also improved. Conclusion: The results of this study indicate that the application of EBN to nursing management clinical practicum is effective to improve EBN competency in undergraduate students and should be further applied in nursing education using the systematic strategies.

프리미엄 디지털 컨버전스 제품의 수용과 확산에 대한 연구: 사회적 가치의 조절효과를 중심으로 (Exploratory Study of Adoption and Diffusion of Premium Digital Convergence Product: Moderating Effecting of Social Value)

  • 송영희;허원무
    • 지식경영연구
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    • 제12권1호
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    • pp.53-76
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    • 2011
  • This study aims to examine the effects of on premium convergence products buying behavior. This paper analyzed the positive attitude formation using the basic and extended TAM and also revealed how the positive premium convergence product attitude relate to relationship purchasing intention and word of mouth intention. The samples of 562 consumer indicate that the antecedents are consist of four dimension(perceived usefulness, perceived ease of use, social value) and attitude is developed into buying intention and word of mouth intention. We have reached the following conclusion about the antecedents and outcomes factors of customer attitude for the launch of premium convergence product. First, perceived usefulness, perceived delight, and social value had a positive effect on customer attitude but perceived ease of use did not. Second, we found that customer attitude had a positive effect on purchase intention and word-of mouth intention. Finally, interaction effect of perceived usefulness/perceived delight and social value had a positive effect on customer attitude. Our findings suggested that adoptian and diffusion of premium convergence product is influenced by several behavior factors. Managerially, our result emphasize that premium convergence products must satisfy not only the perceived usefulness/delight but also social value that consumers are seeking in order to be successful in the market. The theoretical and practical implications of these findings are discussed as well.

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Neurologic Outcomes of Preoperative Acute Silent Cerebral Infarction in Patients with Cardiac Surgery

  • Sim, Hyung Tae;Kim, Sung Ryong;Beom, Min Sun;Chang, Ji Wook;Kim, Na Rae;Jang, Mi Hee;Ryu, Sang Wan
    • Journal of Chest Surgery
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    • 제47권6호
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    • pp.510-516
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    • 2014
  • Background: Acute cerebral infarction is a major risk factor for postoperative neurologic complications in cardiac surgery. However, the outcomes associated with acute silent cerebral infarction (ASCI) have not been not well established. Few studies have reported the postoperative outcomes of these patients in light of preoperative Diffusion-weighted magnetic resonance imaging (DWI). We studied the postoperative neurologic outcomes of patients with preoperative ASCI detected by DWI. Methods: We retrospectively studied 32 patients with preoperative ASCI detected by DWI. None of the patients had preoperative neurologic symptoms. The mean age at operation was $68.8{\pm}9.5$ years. Five patients had previous histories of stroke. Four patients had been diagnosed with infective endocarditis. Single cerebral infarct lesions were detected in 16 patients, double lesions in 13, and multiple lesions (>5) in three. The median size of the infarct lesions was 4 mm (range, 2 to 25 mm). The operations of three of the 32 patients were delayed pending follow-up DWI studies. Results: There were two in-hospital mortalities. Neurologic complications also occurred in two patients. One patient developed extensive cerebral infarction unrelated to preoperative infarct lesions. One patient showed sustained delirium over one week but recovered completely without any neurologic deficits. In two patients, postoperative DWI confirmed that no significant changes had occurred in the lesions. Conclusion: Patients with preoperative ASCI showed excellent postoperative neurologic outcomes. Preoperative ASCI was not a risk factor for postoperative neurologic deterioration.

한국형 국제국방산업협력제도 도입시 방산협력국가 수요확산 예측 연구 (Forecasting the Diffusion of Participating Countries with the Introduction of the "International Defense Industry Cooperation Program of Korea")

  • 남명렬;강석중
    • 한국정보통신학회논문지
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    • 제25권9호
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    • pp.1234-1243
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    • 2021
  • 본 연구에서는 한국 방산분야에서 정부분야 경쟁력 향상을 위하여 미국의 FMS 제도를 모델로 하여 한국형 G to G 방위산업협력을 위한 국제국방산업협력제도 도입 시, 국방산업협력국가 확산이 어떻게 이루어질 것인지를 Bass 모델을 통해 예측한다. 이를 위해 미국의 FMS에 참여한 국가 데이터를 기반으로 수요국가 확산을 설명할 수 있는 확산계수와 모방계수를 추정하였다. 또한 이 계수들에 대하여 미국과 한국의 정부분야 경쟁력 차이와 종합적인 방산 경쟁력 차이를 적용하여 한국의 상황을 고려한 확산 패턴을 예측하였고, 조기에 확산을 이룰 수 있는 방안을 제시한다. 한국은 국제방산시장에서 모방구매자들에게 상대적인 우위를 점할 수 있을 것으로 보이며, 확산을 조기화하기 위해서는 Medium-High급 무기체계에서의 경쟁력을 High급까지 확장시켜야 하며, 미국의 FMS에서 정부가 주도하지 않는 절충교역 분야인 산업협력을 포함한 대안 제공을 강화하여야 한다.

셀룰러 오토마톤 법을 이용한 콘크리트의 염화물이온 확산현상의 해석적 연구 (An Analytical Study of Chloride Ion Diffusion in Concrete via Cellular Automaton Method)

  • 김정진;석원균
    • 한국건축시공학회지
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    • 제24권5호
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    • pp.541-552
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    • 2024
  • 본 연구에서는 콘크리트 내부의 복잡한 공극 구조를 고려하여 콘크리트에서 발생되는 열화 정도를 예측하는데, 콘크리트 내부에서의 모세관 작용 및 공극 분포에 의해 발생하는 기체와 액체 계면에서의 압력 저하를 구동력으로 한 수분 이동과 공극률 및 확산계수가 염화물이온의 침투 거동에 미치는 영향을 검토하여 Cellular Automaton Method(이하, CAM)라는 새로운 해석모델을 구축하였다. 이를 통해 40% 이하의 공극률을 가진 콘크리트 조직 내 수분 이동과 공극률 40% 이상에서의 수분 이동 현상을 검토하였으며, 수분이 침투한 영역에 한해서 확산계수에 따른 염화물이온의 확산 현상과 Finite Element Method(이하, FEM)의 확산해석 결과를 비교 분석한 결과, FEM과 CAM 해석결과 값의 최대 편차가 0.989%로, 두 모델이 상당히 일치함이 확인되어, 실제의 염해 환경에서 콘크리트 내 염화물이온 확산 과정을 시뮬레이션하기 위해서는 CAM이 적합할 것으로 사료된다.

Clinical Analysis Comparing Efficacy between a Distal Filter Protection Device and Proximal Balloon Occlusion Device during Carotid Artery Stenting

  • Lee, Jong Hyeok;Sohn, Hee Eon;Chung, Seung Young;Park, Moon Sun;Kim, Seong Min;Lee, Do Sung
    • Journal of Korean Neurosurgical Society
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    • 제58권4호
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    • pp.316-320
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    • 2015
  • Objective : The main concern during transfemoral carotid artery stenting (CAS) is preventing cerebral embolus dislodgement. We compared clinical outcomes and intraprocedural embolization rates of CAS using a distal filter protection device or proximal balloon occlusion device. Methods : From January 2011 to March 2015, a series of 58 patients with symptomatic or asymptomatic internal carotid artery stenosis ${\geq}70%$ were treated with CAS with embolic protection device in single center. All patients underwent post-CAS diffusion-weighted magnetic resonance imaging (DW-MRI) to detect new ischemic lesions. We compared clinical outcomes and postprocedural embolization rates. Results : CAS was performed in all 61 patients. Distal filter protection success rate was 96.6% (28/29), whose mean age was 70.9 years, and mean stenosis was 81%. Their preprocedural infarction rate was 39% (11/28). Subsequent DW-MRI revealed 96 new ischemic lesions in 71% (20/28) patients. In contrast, the proximal balloon occlusion device success rate was 93.8% (30/32), whose mean age was 68.8 years and mean stenosis was 86%. Preprocedure infarction rate was 47% (14/30). DW-MRI revealed 45 new ischemic lesions in 57% (17/30) patients. Compared with distal filter protection device, proximal balloon occlusion device resulted in fewer ischemic lesions per patient (p=0.028). In each group, type of stent during CAS had no significant effect on number of periprocedural embolisms. Only 2 neurologic events occurred in the successfully treated patients (one from each group). Conclusion : Transfemoral CAS with proximal balloon occlusion device achieves good results. Compared with distal filter protection, proximal balloon occlusion might be more effective in reducing cerebral embolism during CAS.

Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Cerebral Venous Thrombosis : A Meta-Analysis

  • Lv, Bin;Jing, Feng;Tian, Cheng-lin;Liu, Jian-chao;Wang, Jun;Cao, Xiang-yu;Liu, Xin-feng;Yu, Sheng-yuan
    • Journal of Korean Neurosurgical Society
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    • 제64권3호
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    • pp.418-426
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    • 2021
  • Objective : A role of diffusion-weighted imaging (DWI) in the diagnosis of cerebral venous thrombosis (CVT) is not well-understood. This study evaluates the effectiveness of DWI in the diagnosis of CVT. Methods : Literature search was conducted in electronic databases for the identification of studies which reported the outcomes of patients subjected to DWI for CVT diagnosis. Random-effects meta-analyses were performed to achieve overall estimates of important diagnostic efficiency indices including hyperintense signal rate, the sensitivity and specificity of DWI in diagnosing CVT, and the apparent diffusion coefficient (ADC) of DWI signal areas and surrounding tissue. Results : Nineteen studies (443 patients with 856 CVTs; age 40 years [95% confidence interval (CI), 33 to 43]; 28% males [95% CI, 18 to 38]; symptom onset to DWI time 4.6 days [95% CI, 2.3 to 6.9]) were included. Hyperintense signals on DWI were detected in 40% (95% CI, 26 to 55) of the cases. The sensitivity of DWI for detecting CVT was 22% (95% CI, 11 to 34) but specificity was 98% (95% CI, 95 to 100). ADC values were quite heterogenous in DWI signal areas. However, generally the ADC values were lower in DWI signal areas than in surrounding normal areas (mean difference-0.33×10-3 ㎟/s [95% CI, -0.44 to -0.23]; p<0.00001). Conclusion : DWI has a low sensitivity in detecting CVT and thus has a high risk of missing many CVT cases. However, because of its high specificity, it may have supporting and exploratory roles in CVT diagnosis.